inmide 1.5mg tablet sr - Indapamide (1.5mg) medicine

Divret Tablet PR (Indapamide 1.5mg): Complete Medicine Guide

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🏭 East West Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use during pregnancy only if clearly needed and after consulting your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and edema.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Irregular heartbeat or palpitations
  • Muscle cramps or weakness
  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing
  • Severe abdominal pain with nausea and vomiting
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is inmide 1.5mg tablet sr used for?

This medicine contains Indapamide 1.5mg, a thiazide-like diuretic used to treat high blood pressure and fluid retention. It works by helping the kidneys remove excess salt and water, and by relaxing blood vessels. It is usually taken once daily in the morning.

  • Generic Name: Indapamide (1.5mg)
  • Manufacturer: East West Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 inmide 1.5mg tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा इंडापामाइड 1.5mg से बनी है और मुख्य रूप से उच्च रक्तचाप (हाई ब्लड प्रेशर) और शरीर में पानी के जमाव (सूजन) के इलाज के लिए इस्तेमाल की जाती है। यह किडनी को अतिरिक्त नमक और पानी बाहर निकालने में मदद करती है, जिससे रक्तचाप कम होता है और सूजन कम होती है। यह दवा आमतौर पर दिन में एक बार सुबह लेने की सलाह दी जाती है। इसे डॉक्टर की सलाह के बिना बंद या शुरू न करें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, सिरदर्द, कमजोरी और बार-बार पेशाब आना शामिल हैं। कुछ लोगों में पोटैशियम या सोडियम की कमी हो सकती है, जिससे मांसपेशियों में ऐंठन, भ्रम या दिल की धड़कन अनियमित हो सकती है। अगर आपको चेहरे, होंठ या जीभ में सूजन, सांस लेने में कठिनाई, या गंभीर दाने दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर किडनी या लिवर की बीमारी, डायबिटीज, गाउट या ल्यूपस। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। इस दवा के साथ शराब न लें। पर्याप्त पानी पिएं। डॉक्टर समय-समय पर खून की जांच करने की सलाह दे सकते हैं। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के यह दवा न लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 inmide 1.5mg tablet sr Uses & Benefits

[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure, reducing the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"},{"condition":"Edema","description":"It helps relieve fluid retention (edema) associated with heart failure, liver cirrhosis, or kidney disease.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Calcium nephrolithiasis","description":"Sometimes prescribed off-label to reduce calcium excretion in people with recurrent calcium kidney stones.","evidence":"Limited"},{"condition":"Diabetes insipidus","description":"Rarely used off-label to reduce urine output in nephrogenic diabetes insipidus.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Edema due to heart failure, Edema due to liver cirrhosis, Edema due to kidney disease

📋 Drug Information

Generic Name(s)Indapamide (1.5mg)
Brand Nameinmide 1.5mg tablet sr
ManufacturerEast West Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassLow-ceiling Diuretics (Inhibitors of Na+Cl symport)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine in the morning to avoid frequent urination at night.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Stay hydrated, but avoid excessive fluid intake unless advised.
4
Include potassium-rich foods like bananas, oranges, and spinach in your diet, as this medicine can lower potassium levels.
5
Avoid alcohol as it can increase dizziness and low blood pressure.
6
Do not stop this medicine suddenly without consulting your doctor, as it can cause rebound hypertension.
7
Report any muscle cramps, weakness, or irregular heartbeat to your doctor promptly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Swelling in legs or abdomen
This medicine helps reduce fluid retention.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and completely absorbed from the gastrointestinal tract after oral administration. The bioavailability is approximately 93%. Food may slightly delay the absorption but does not significantly affect the extent of absorption.
DistributionThis medicine is widely distributed in the body. It is highly bound to plasma proteins and has a large volume of distribution. It crosses the placental barrier and is excreted in breast milk.
Protein BindingApproximately 71-79% of this medicine is bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, although the specific isoenzymes are not fully characterized. The metabolites are largely inactive.
Half-LifeThe elimination half-life of this medicine is approximately 14-18 hours.
ExcretionThis medicine and its metabolites are primarily excreted by the kidneys. About 60-70% of an oral dose is excreted in the urine, and a smaller amount is excreted in the feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 93%.
Onset of ActionThe diuretic effect of this medicine begins within 1-2 hours after oral administration. The antihypertensive effect may take several days to weeks to fully develop.
Peak Plasma TimePeak plasma concentrations of this medicine are reached approximately 1-2 hours after oral administration.
Duration of ActionThe diuretic effect of this medicine lasts for about 24-36 hours. The antihypertensive effect persists with once-daily dosing.

How It Works

This medicine works primarily by inhibiting the reabsorption of sodium and chloride in the distal convoluted tubule of the kidney. This action increases the excretion of sodium, chloride, and water, leading to diuresis and a reduction in blood volume. Additionally, it causes vasodilation by opening potassium channels, which directly relaxes blood vessels. These combined effects lower blood pressure and reduce edema.

Mechanism Steps

1
Inhibition of sodium reabsorption: This medicine inhibits the sodium-chloride symporter in the distal convoluted tubule, reducing sodium reabsorption.
2
Increased diuresis: The increased sodium and chloride in the urine draw water with them, leading to increased urine production.
3
Vasodilation: This medicine opens potassium channels in vascular smooth muscle, causing relaxation and widening of blood vessels.
4
Blood pressure reduction: The combined effects of reduced blood volume and vasodilation lead to a decrease in blood pressure.

💡 How to Take inmide 1.5mg tablet sr

Strength: This medicine is available as a 1.5 mg immediate-release tablet.

1Take this medicine orally with a glass of water.
2Take it at the same time each day, preferably in the morning.
3You can take it with or without food, but taking it with food may reduce stomach upset.
4Swallow the tablet whole; do not crush or chew.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 1.5 mg taken orally once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and kidney function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and electrolyte imbalances. Start with a low dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with mild to moderate renal impairment, no dose adjustment is usually needed. However, in severe renal impairment (creatinine clearance <30 mL/min), this medicine is contraindicated. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, use with caution. In severe hepatic impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 1.5 mg. Higher doses do not provide additional antihypertensive benefit but increase the risk of side effects.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Potassium-rich foods (bananas, oranges, spinach)
Include in diet
Helps prevent potassium loss caused by the medicine.
High-sodium foods
Limit
Excess sodium can counteract the blood pressure lowering effect.
Alcohol
Avoid
Increases dizziness and low blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of inmide 1.5mg tablet sr

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid driving if dizzy. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Rest and stay hydrated. Consult doctor if severe or persistent.
Weakness (Common (5-10%))
Ensure adequate rest and hydration. Report to doctor if it interferes with daily activities.
Increased urination (Common (5-10%))
Take the medicine in the morning to avoid nighttime urination. Consult doctor if excessive.

🚨 Serious Side Effects

Severe electrolyte imbalance (e.g., hypokalemia, hyponatremia) (Uncommon (0.1-1%))
Seek immediate medical attention if you experience muscle cramps, confusion, irregular heartbeat, or extreme fatigue.
Allergic reaction (angioedema, anaphylaxis) (Rare (<0.1%))
Seek emergency help if you notice swelling of face, lips, tongue, or throat, difficulty breathing, or severe rash.
Pancreatitis (Rare (<0.1%))
Seek immediate medical attention if you have severe abdominal pain that radiates to your back, with nausea and vomiting.
Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) (Rare (<0.1%))
Stop the medicine and seek emergency care if you develop a painful rash with blisters, peeling skin, or sores in the mouth.

⚠️ Rare Side Effects

Liver damage (hepatotoxicity)
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Acute myopia and angle-closure glaucoma
Seek immediate ophthalmological care if you experience sudden eye pain, blurred vision, or seeing halos around lights.
Blood dyscrasias (e.g., leukopenia, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor promptly.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Lithium Major
NSAIDs Moderate
Corticosteroids Major
Digoxin Moderate
Oral antidiabetic drugs Moderate
Cholestyramine Minor
Calcium supplements Minor
Other antihypertensives Major
Alcohol Moderate
Licorice Minor

🚨 Major Interactions

  • Lithium
  • Other antihypertensive drugs
  • Corticosteroids

⚡ Moderate Interactions

  • NSAIDs
  • Digoxin
  • Oral antidiabetic drugs

🍷 Alcohol Interaction

Alcohol may increase the blood pressure lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid alcohol or limit its consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to indapamide or other sulfonamide-derived drugs","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["This medicine may cause electrolyte imbalances. Regular monitoring of blood electrolytes is recommended.","It can cause dizziness and low blood pressure. Avoid driving or operating machinery until you know how it affects you.","It may worsen glucose tolerance and increase blood sugar levels in diabetic patients.","It can increase uric acid levels and precipitate gout attacks.","It may cause photosensitivity reactions. Avoid excessive sun exposure and use sunscreen.","It can cause acute angle-closure glaucoma. Seek immediate medical attention if you experience eye pain or blurred vision.","It may cause severe skin reactions. Stop the medicine and seek medical help if you develop a rash."]

🤱 Lactation Safety

This medicine is excreted in breast milk. It is not recommended during breastfeeding as it may cause serious adverse effects in the nursing infant. Consult your doctor for alternative treatments.

💊 Overdose Management

Overdose of this medicine can cause excessive diuresis, leading to dehydration, electrolyte imbalances, and hypotension. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic, including fluid and electrolyte replacement. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor about all your medical conditions, especially kidney or liver disease, diabetes, gout, or lupus. Tell your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, as this medicine can interact with many substances. Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Stay well hydrated, but do not drink excessive amounts of water unless advised. Your doctor may recommend regular blood tests to monitor your kidney function, electrolyte levels, and blood sugar. Do not use this medicine if you are pregnant or planning to become pregnant without consulting your doctor. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose; never double the dose. Keep this medicine out of reach of children and store it as directed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the effects of this medicine, especially dizziness, electrolyte imbalances, and kidney function changes. Start with a low dose and monitor closely. Regular blood tests are recommended.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery to avoid electrolyte imbalances and low blood pressure during the procedure.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or dizziness. Maintain good oral hygiene and stay hydrated during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking, swimming, or cycling.
😴
Reduce salt intake to enhance the blood pressure lowering effect.
💧
Limit alcohol and avoid smoking.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep to support overall health.

🏋️ Exercise Considerations

This medicine can cause dizziness and low blood pressure, especially when standing up quickly. Avoid strenuous exercise initially until you know how the medicine affects you. Stay hydrated during exercise. If you feel dizzy or weak, stop and rest.

🥗 Diet Recommendations

Include potassium-rich foods like bananas, oranges, and spinach.
Reduce sodium intake by avoiding processed and canned foods.
Eat a balanced diet rich in fruits, vegetables, and whole grains.
Limit caffeine and alcohol.
Stay well hydrated unless advised otherwise.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or lightheadedness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause increased urination, so plan your work schedule accordingly. Most people can continue their normal activities with some adjustments.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects like allergic reactions, severe dizziness, or irregular heartbeat, seek immediate medical attention. Your doctor may adjust the dose or switch to a different medicine if needed.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to electrolyte imbalances, increased blood sugar, and increased uric acid levels. Regular monitoring of blood tests is recommended. It may also reduce kidney function over time, especially in patients with pre-existing kidney disease. Periodic review with your doctor is essential to adjust the dose and monitor for side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and weight loss can help control blood pressure and reduce the need for medication.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, ARBs, calcium channel blockers, or beta-blockers may be used as alternatives or in combination.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, continue taking your dose at the same local time as usual, but consult your doctor if you are unsure. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with high blood pressure
He was prescribed this medicine 1.5 mg once daily. After a few weeks, his blood pressure improved significantly. He experienced mild dizziness initially but it subsided. He now takes it regularly in the morning and monitors his blood pressure at home.
💡 Lesson: Consistent daily dosing and regular monitoring help achieve good blood pressure control.
👤 A 62-year-old woman with heart failure and leg swelling
She started this medicine to reduce edema. Her swelling decreased, but she developed muscle cramps due to low potassium. Her doctor adjusted her diet and added a potassium supplement. She now feels much better.
💡 Lesson: Regular blood tests to monitor electrolytes are important while taking this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The diuretic effect starts within 1-2 hours, but the full blood pressure lowering effect may take several weeks.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you remember within 12 hours, take it. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe to take this medicine during pregnancy?

A: It is not recommended during pregnancy. Consult your doctor for alternative treatments.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, do not stop without consulting your doctor. Stopping suddenly can cause blood pressure to rise again.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for inmide 1.5mg tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure high blood pressure permanently.
    Fact: This medicine controls high blood pressure but does not cure it. You may need to take it long-term.
  • Myth: You can stop taking this medicine once your blood pressure is normal.
    Fact: Stopping suddenly can cause blood pressure to rise again. Always consult your doctor before stopping.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with certain conditions like severe kidney or liver disease, or during pregnancy.

🔄 Alternative Options

Generic Alternatives

  • Indapamide 1.5mg Tablet

Brand Alternatives

  • Divret Tablet PR

📊 Comparison with Similar Medicines

[{"medicine":"Indapamide","class":"Thiazide-like diuretic","duration":"24-36 hours","common_uses":"Hypertension, edema"},{"medicine":"Hydrochlorothiazide","class":"Thiazide diuretic","duration":"6-12 hours","common_uses":"Hypertension, edema"},{"medicine":"Chlorthalidone","class":"Thiazide-like diuretic","duration":"24-72 hours","common_uses":"Hypertension, edema"}]

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