injek 10mg injection - Phytomenadione (10mg) medicine

Injek 10mg Injection (Phytomenadione): Complete Medicine Guide

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🏭 Neon Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or shortness of breath
  • Swelling of the face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Chest pain or tightness
  • Rapid heartbeat or palpitations
  • Severe allergic rash or hives
  • Bleeding that does not stop after treatment

If experiencing severe symptoms, call emergency services immediately.

What is injek 10mg injection used for?

This medicine is a vitamin K1 injection used to treat and prevent bleeding caused by vitamin K deficiency or warfarin overdose. It works by helping the liver produce clotting factors. It is given by a healthcare professional and is essential for newborns to prevent serious bleeding.

  • Generic Name: Phytomenadione (10mg)
  • Manufacturer: Neon Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 injek 10mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा फाइटोमेनाडियोन (विटामिन K1) का इंजेक्शन है, जिसका उपयोग विटामिन K की कमी या वारफेरिन जैसी दवाओं के कारण होने वाले रक्तस्राव को रोकने और इलाज करने के लिए किया जाता है। यह शरीर में रक्त का थक्का बनाने वाले प्रोटीन को सक्रिय करने में मदद करती है। यह नवजात शिशुओं में रक्तस्राव की बीमारी को रोकने के लिए भी दी जाती है। यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा इंजेक्शन के रूप में दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, सूजन या लालिमा शामिल है, जो आमतौर पर कुछ दिनों में ठीक हो जाती है। कुछ लोगों को हल्की रैश, खुजली या चकत्ते हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी की प्रतिक्रिया जैसे सांस लेने में कठिनाई, चेहरे या गले में सूजन, या रक्तचाप में अचानक गिरावट हो सकती है। अगर ऐसा कुछ हो तो तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। अगर आपको विटामिन K या किसी अन्य दवा से एलर्जी है, तो डॉक्टर को बताएं। अपनी सभी दवाओं के बारे में डॉक्टर को जानकारी दें, खासकर खून पतला करने वाली दवाओं के बारे में। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इंजेक्शन के बाद चक्कर आने पर वाहन न चलाएं। शराब का सेवन न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 injek 10mg injection Uses & Benefits

[{"condition":"Warfarin overdose","description":"This medicine is used to reverse excessive anticoagulation caused by warfarin, helping to restore normal clotting and stop bleeding.","evidence":"Well-established"},{"condition":"Vitamin K deficiency bleeding","description":"It treats bleeding due to low vitamin K levels, which can occur in malabsorption, biliary obstruction, or prolonged antibiotic use.","evidence":"Well-established"},{"condition":"Hemorrhagic disease of the newborn","description":"This medicine is given to newborns to prevent and treat vitamin K deficiency bleeding, a serious condition that can cause intracranial hemorrhage.","evidence":"Well-established"},{"condition":"Prevention of bleeding in patients with malabsorption","description":"Patients with conditions like cystic fibrosis or celiac disease may not absorb enough vitamin K and may need this medicine to prevent bleeding.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Prevention of bleeding in patients on long-term antibiotics","description":"Sometimes prescribed off-label when broad-spectrum antibiotics disrupt gut flora that normally produce vitamin K.","evidence":"Limited"}]

Primary treatment for: Vitamin K deficiency bleeding

Also treats: Warfarin overdose, Hemorrhagic disease of the newborn, Malabsorption syndromes, Biliary obstruction

📋 Drug Information

Generic Name(s)Phytomenadione (10mg)
Brand Nameinjek 10mg injection
ManufacturerNeon Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassVitamins
Route of AdministrationParenteral (intramuscular or intravenous injection)
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization recommends vitamin K prophylaxis for all newborns to prevent vitamin K deficiency bleeding. This medicine is on the WHO Model List of Essential Medicines.
ICMR GuidelineThe Indian Council of Medical Research recommends vitamin K prophylaxis for newborns as per national guidelines. Consult local guidelines for specific recommendations.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this medicine slowly intravenously to avoid anaphylactoid reactions.
2
Monitor INR closely when using this medicine to reverse warfarin; effects may take 6-12 hours.
3
For newborns, give a single intramuscular dose of 0.5-1 mg as per guidelines.
4
Avoid intramuscular injection in patients on anticoagulants due to risk of hematoma.
5
Keep epinephrine and resuscitation equipment ready when administering intravenous phytomenadione.
6
Educate patients on the signs of allergic reactions and when to seek help.
7
Use the smallest effective dose to minimize risk of adverse effects.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Unexplained bleeding or bruising
This medicine is used to treat bleeding due to vitamin K deficiency.
Likely Use
High INR on warfarin
This medicine is used to reverse warfarin overdose.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered by injection, so absorption is not required. It is directly introduced into the bloodstream or muscle tissue, ensuring rapid availability.
DistributionAfter injection, phytomenadione is transported in the blood bound to lipoproteins and is taken up primarily by the liver, where it exerts its effects.
Protein BindingPhytomenadione is highly bound to plasma lipoproteins.
MetabolismThis medicine is metabolized in the liver to more polar metabolites, including phytomenadione epoxide, which can be reduced back to the active form.
Half-LifeThe elimination half-life of phytomenadione is approximately 1 to 2 hours, but its biological effect lasts longer due to the time required for clotting factor synthesis.
ExcretionMetabolites of this medicine are excreted mainly in bile and urine.
BioavailabilityBioavailability is not applicable for injectable administration, as it is directly delivered into the systemic circulation.
Onset of ActionThe onset of action depends on the route of administration and the severity of deficiency. When given intravenously, effects on bleeding may begin within 1 to 2 hours, but correction of INR may take 6 to 12 hours.
Peak Plasma TimePeak plasma concentration is reached within 1 to 2 hours after intramuscular injection.
Duration of ActionThe duration of action of this medicine is typically 12 to 24 hours, but the clinical effect may last longer as clotting factors are replenished.

How It Works

This medicine provides a synthetic form of vitamin K1, which is essential for the gamma-carboxylation of glutamate residues in clotting factors II, VII, IX, and X, as well as proteins C and S. This carboxylation is necessary for these factors to bind calcium and become functionally active in the coagulation cascade. By supplying vitamin K1, this medicine restores the liver's ability to produce active clotting factors, thereby correcting bleeding tendencies caused by vitamin K deficiency or warfarin therapy.

Mechanism Steps

1
Provision of vitamin K1: This medicine delivers phytomenadione, a fat-soluble vitamin that is taken up by the liver.
2
Activation of vitamin K-dependent carboxylase: In the liver, phytomenadione is reduced to its active form, which serves as a cofactor for the enzyme gamma-glutamyl carboxylase.
3
Gamma-carboxylation of clotting factors: The active vitamin K enables the carboxylation of glutamate residues on clotting factors II, VII, IX, and X, allowing them to bind calcium.
4
Restoration of coagulation: The newly carboxylated clotting factors become functional, leading to improved clot formation and cessation of bleeding.

💡 How to Take injek 10mg injection

Strength: Injection: 10 mg per vial (or as specified by the manufacturer).

1This medicine is given by a healthcare professional as an intramuscular or intravenous injection.
2Do not attempt to self-administer this injection.
3For intramuscular injection, the site is usually the upper outer quadrant of the buttock or the deltoid muscle.
4For intravenous injection, it is given slowly over 1 to 2 minutes to avoid adverse reactions.
5After injection, remain under observation for at least 15 to 30 minutes to monitor for allergic reactions.
6Follow your doctor's instructions for follow-up blood tests to monitor clotting.

Dosage Information

Adult DosageThe dose of this medicine is individualized by a qualified clinician based on the indication, severity of deficiency, and patient's clinical status. For warfarin reversal, typical doses range from 1 mg to 10 mg given intravenously or intramuscularly, depending on the INR. For vitamin K deficiency bleeding, doses may range from 5 mg to 10 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. For newborns, a single intramuscular dose of 0.5 mg to 1 mg is commonly given to prevent vitamin K deficiency bleeding, but this must be determined by a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose should be individualized by a clinician based on clinical response and renal/hepatic function.
Renal ImpairmentNo dose adjustment is typically required for renal impairment. However, consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with severe liver disease, the effectiveness of this medicine may be reduced. Dose should be individualized by a clinician.
Maximum Daily DoseThe maximum daily dose is determined by the treating clinician based on the indication. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No specific food interactions
Normal diet
This medicine is given by injection and does not interact with food directly.

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled dose
→ Contact your healthcare provider for instructions.
💡 Do not self-administer an extra dose.

⚠️ Side Effects of injek 10mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress to the area. Consult your doctor if pain persists or worsens.
Injection site swelling or redness (Common (5-10%))
Usually resolves on its own. Keep the area clean and avoid scratching.
Mild rash (Uncommon (1-5%))
Inform your doctor if the rash spreads or is accompanied by other symptoms.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical attention immediately if you experience difficulty breathing, swelling of the face or throat, or a sudden drop in blood pressure.
Severe allergic reaction (Rare (<0.1%))
Call for emergency help if you notice hives, itching, or swelling beyond the injection site.
Cardiac arrest (Very rare (<0.01%))
This can occur if the injection is given too rapidly intravenously. It is managed by healthcare professionals.

⚠️ Rare Side Effects

Dizziness
Sit or lie down until the feeling passes. Avoid driving or operating machinery.
Sweating
Stay hydrated and inform your doctor if it persists.
Chest tightness
Seek immediate medical attention.
Metallic taste
Usually temporary. Inform your doctor if it bothers you.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Cephalosporins Moderate
Cholestyramine Moderate

🚨 Major Interactions

  • Warfarin

⚡ Moderate Interactions

  • Antibiotics (e.g., cephalosporins)
  • Bile acid sequestrants (e.g., cholestyramine)

🍷 Alcohol Interaction

Alcohol may impair liver function and reduce the effectiveness of this medicine. It is advisable to avoid alcohol while receiving treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to phytomenadione or any component of the injection.","Severe liver disease with impaired bile secretion, as this may reduce the effectiveness of the medicine."]

⚠️ Warnings & Precautions

["This medicine should be given only by a healthcare professional.","Intravenous administration should be done slowly to avoid anaphylactoid reactions.","Use with caution in patients with known allergies to vitamin K.","Monitor INR closely when used to reverse warfarin effects.","Avoid intramuscular injection in patients with bleeding disorders or on anticoagulants, as it may cause hematoma.","Inform your doctor if you are pregnant or breastfeeding.","Do not use if the solution is discolored or contains particles."]

🤱 Lactation Safety

This medicine is considered safe during breastfeeding. It is not known to pass into breast milk in significant amounts, but consult your doctor before use.

💊 Overdose Management

Overdose of this medicine is unlikely to cause serious harm because it is a vitamin. However, excessive doses may lead to transient hypercoagulability or allergic reactions. Treatment is supportive and symptomatic. In case of accidental overdose, contact a healthcare professional immediately.

⏰ Missed Dose

This medicine is usually given as a single dose or as directed by your doctor. If you miss a scheduled dose, contact your healthcare provider for instructions. Do not self-administer an extra dose.

Additional Safety Advice

General Safety

This medicine must be given by a healthcare professional only. Do not attempt to self-administer this injection. Inform your doctor if you are allergic to vitamin K or any other medicines. Tell your doctor about all medicines you are taking, especially blood thinners like warfarin, because this medicine can reverse their effects. If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor before receiving this medicine. Avoid alcohol while receiving treatment, as it may affect liver function and clotting. Do not drive or operate heavy machinery immediately after the injection if you feel dizzy or unwell. Keep all follow-up appointments so your doctor can monitor your response to treatment.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced liver function, which can affect the response to this medicine. Doses should be individualized, and monitoring of INR is recommended.

🤰 Pregnancy Planning (TTC)

This medicine is safe to use during pregnancy when clinically indicated. If you are planning pregnancy and have a bleeding disorder or are on warfarin, consult your doctor to optimize treatment.

🏥 Post-Surgery Considerations

This medicine may be used after surgery to reverse anticoagulation or treat bleeding. Follow your surgeon's instructions regarding activity and monitoring.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine, especially if you are on anticoagulants. It may affect bleeding during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a balanced diet rich in vitamin K to support overall health.
🥗
Avoid excessive alcohol consumption to protect liver function.
😴
Follow up regularly with your doctor for monitoring.
💧
Inform all healthcare providers about your use of this medicine.
🧘
Practice good hygiene to prevent infections that could complicate bleeding disorders.

🏋️ Exercise Considerations

Avoid activities that may cause injury or bleeding, especially if you have a bleeding disorder. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include vitamin K-rich foods like leafy greens, broccoli, and Brussels sprouts.
Maintain consistent vitamin K intake if on warfarin.
Stay well hydrated.
Limit alcohol consumption.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or allergic reactions. Avoid driving or operating heavy machinery immediately after injection until you know how it affects you. Most people can resume normal activities after the effect wears off.

🛑 When to Stop This Medicine

This medicine is usually given as a single dose or short course. Do not stop or change the regimen without consulting your doctor. If you experience severe side effects, seek medical attention immediately.

📅 Long-Term Use Effects

Long-term effects of this medicine are not a concern when used appropriately, as it is a vitamin. However, repeated use may be necessary in chronic malabsorption conditions. Monitoring of clotting parameters and underlying conditions is recommended. There is no known toxicity from long-term use at recommended doses.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral vitamin K supplements

May be used for mild deficiency but is less effective in acute bleeding.

Evidence: Well-established
Fresh frozen plasma (FFP) or prothrombin complex concentrate (PCC)

Used for urgent reversal of anticoagulation when vitamin K alone is insufficient.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about your medication before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Protect from light

❌ DON'T

Do not use if solution is discolored or contains particles

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label intact. Keep a copy of your prescription and a letter from your doctor explaining the need for the injection. Store it at room temperature and protect it from light. If traveling across time zones, consult your doctor about timing of doses. Declare it at customs if required. Always carry it in your hand luggage if flying, and inform security personnel that it is a prescribed medicine.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 65-year-old man on warfarin for atrial fibrillation
He was brought to the emergency room with severe nosebleeds and bruising. His INR was dangerously high at 8.5. He received an injection of this medicine, and within 12 hours his INR dropped to 2.5, and the bleeding stopped. He was advised to continue warfarin at a lower dose with regular monitoring.
💡 Lesson: This medicine effectively reverses warfarin overdose, but close monitoring and dose adjustment of warfarin are essential.
👤 A newborn baby born at home without vitamin K prophylaxis
The baby developed bleeding from the umbilical stump and was diagnosed with vitamin K deficiency bleeding. A single intramuscular injection of this medicine stopped the bleeding within hours. The baby recovered fully and was discharged with advice for future prophylaxis.
💡 Lesson: Vitamin K prophylaxis at birth is crucial to prevent serious bleeding in newborns.

💬 Questions Patients Often Ask

Q: How long does it take for this medicine to work?

A: When given intravenously, effects on bleeding may begin within 1-2 hours, but full correction of clotting may take 6-12 hours.

Q: Can I receive this medicine if I am pregnant?

A: This medicine is considered safe in pregnancy when clinically indicated. It is routinely given to newborns. Consult your doctor for individualized advice.

Q: What are the storage requirements for this medicine?

A: Store at room temperature (15-30°C), protect from light, and do not freeze. Keep in the original container.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can this medicine be given at home?
  • How long does the effect last?
  • Is it safe for pregnant women?
  • What if I miss a dose?
  • Can I take alcohol after this injection?
  • Does it interact with other medicines?

🔄 Substitutes for injek 10mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken orally for the same effect.
    Fact: This medicine is formulated for injection. Oral vitamin K is available but may not be as effective in acute bleeding.
  • Myth: This medicine is only for newborns.
    Fact: It is used in adults as well, especially for warfarin reversal and vitamin K deficiency.
  • Myth: This medicine can be self-administered at home.
    Fact: It must be given by a healthcare professional due to the risk of allergic reactions.

🔄 Alternative Options

Generic Alternatives

  • Phytomenadione injection

Brand Alternatives

  • Injek 10mg Injection

📊 Comparison with Similar Medicines

[{"feature":"Route","this_medicine":"Parenteral (IM/IV)","oral_vitamin_k":"Oral"},{"feature":"Onset","this_medicine":"Rapid (1-2 hours)","oral_vitamin_k":"Slower (4-6 hours)"},{"feature":"Use in acute bleeding","this_medicine":"Preferred","oral_vitamin_k":"Less effective"}]

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