indamet 80 capsule - Indacaterol (150mcg) + Mometasone (80mcg) medicine

Indamet 80 Capsule: Complete Medicine Guide

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🏭 Glenmark Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for asthma maintenance in adults and adolescents.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden worsening of breathing or wheezing immediately after inhaling this medicine
  • Swelling of the face, lips, tongue, or throat
  • Severe chest pain or palpitations
  • High fever with difficulty breathing
  • Coughing up blood or blood-tinged sputum
  • Signs of oral fungal infection such as white patches in the mouth
  • Unusual fatigue, muscle weakness, or dizziness

If experiencing severe symptoms, call emergency services immediately.

What is indamet 80 capsule used for?

This medicine is a once-daily inhaled combination of indacaterol and mometasone used for long-term maintenance treatment of asthma in adults and adolescents. It works by opening the airways and reducing inflammation. It is not a rescue inhaler and should not be used for sudden breathing problems.

  • Generic Name: Indacaterol (150mcg) + Mometasone (80mcg)
  • Manufacturer: Glenmark Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 indamet 80 capsule के बारे में (Hindi Summary)

उपयोग: यह दवा इंडैकाटेरोल और मोमेटासोन का संयोजन है, जिसका उपयोग अस्थमा के दीर्घकालिक उपचार के लिए किया जाता है। यह श्वसन मार्ग की सूजन को कम करती है और सांस की नली को खोलती है, जिससे सांस लेने में आसानी होती है। यह दवा अचानक होने वाले अस्थमा के दौरे के लिए नहीं है। इसे रोज एक बार निर्धारित समय पर लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में गले में खराश, सिरदर्द, खांसी, आवाज में भारीपन और मुंह में फंगल संक्रमण शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन सांस लेने में अचानक कठिनाई, चेहरे या गले में सूजन, या दिल की धड़कन तेज होना हो सकता है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने के बाद मुंह को पानी से अच्छी तरह धोएं ताकि मुंह में फंगल संक्रमण न हो। कैप्सूल को निगलें नहीं, इसे इनहेलर के माध्यम से ही लें। अचानक अस्थमा के दौरे के लिए इस दवा का उपयोग न करें; राहत के लिए अलग रेस्क्यू इनहेलर पास रखें। डॉक्टर की सलाह के बिना इस दवा को अचानक बंद न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 indamet 80 capsule Uses & Benefits

[{"condition":"Asthma maintenance in adults and adolescents","description":"Used as a long-term controller therapy to improve lung function and reduce asthma symptoms in patients not adequately controlled on inhaled corticosteroids alone or with other controllers.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD) maintenance","description":"May be used for maintenance treatment of airflow obstruction in selected patients with COPD, although this specific combination and strength is primarily studied in asthma.","evidence":"Limited"}]

Off-label uses: [{"condition":"Exercise-induced bronchoconstriction","description":"Sometimes prescribed off-label for prevention of exercise-induced breathing difficulty, but not a standard first-line use.","evidence":"Limited"}]

Primary treatment for: Asthma

Also treats: Chronic obstructive pulmonary disease (COPD)

📋 Drug Information

Generic Name(s)Indacaterol (150mcg) + Mometasone (80mcg)
Brand Nameindamet 80 capsule
ManufacturerGlenmark Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationInhalation
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place. Keep the capsules in the original blister pack or container and only remove immediately before use. Do not refrigerate or freeze. Keep away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture, or as indicated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Inhale this medicine at the same time every day to maintain consistent lung protection.
2
Always rinse your mouth with water after each inhalation to prevent oral thrush and hoarseness.
3
Keep a short-acting rescue inhaler with you at all times for sudden breathing difficulty.
4
Do not stop this medicine abruptly without consulting your doctor, even if you feel better.
5
Inform your doctor if you have diabetes, heart disease, or thyroid problems before starting this medicine.
6
Use a spacer device if recommended by your doctor to improve drug delivery to the lungs.
7
Regularly clean your inhaler device as per the manufacturer's instructions to ensure proper functioning.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic asthma symptoms
This medicine is commonly prescribed for long-term asthma control.
Likely Use
❌
Sudden asthma attack
This medicine is not a rescue inhaler and should not be used for acute attacks.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter oral inhalation, indacaterol is rapidly absorbed into the bloodstream, with peak plasma concentrations typically reached within 15 minutes to 1 hour. Mometasone is absorbed from the lungs with low systemic bioavailability due to poor gastrointestinal absorption of the swallowed portion. Exact absorption parameters are not established from the available information for this specific fixed-dose combination.
DistributionIndacaterol is highly bound to plasma proteins and has a large volume of distribution, indicating extensive tissue distribution. Mometasone also has a large volume of distribution and is highly protein-bound. Specific distribution data for this combination product are not established from the available information.
Protein BindingIndacaterol is approximately 95% bound to plasma proteins. Mometasone is approximately 98% to 99% bound to plasma proteins. These values are based on data for the individual components.
MetabolismIndacaterol is primarily metabolized in the liver by CYP3A4 and UGT1A1 enzymes. Mometasone undergoes extensive first-pass metabolism in the liver, mainly by CYP3A4. The exact metabolic profile of the fixed-dose combination is not established from the available information.
Half-LifeThe effective half-life of indacaterol is approximately 40 to 56 hours, supporting once-daily dosing. The elimination half-life of mometasone is approximately 5 to 6 hours when given intravenously, but the inhaled formulation has a longer local residence time. Specific half-life data for this combination product are not established from the available information.
ExcretionIndacaterol is excreted mainly in the feces, with a smaller portion in the urine. Mometasone and its metabolites are excreted primarily in the bile and feces, with some renal excretion. Specific excretion data for this combination product are not established from the available information.
BioavailabilityThe absolute bioavailability of inhaled indacaterol is approximately 43% to 45%. The systemic bioavailability of inhaled mometasone is low, approximately 1% or less due to poor oral absorption. Specific bioavailability data for this fixed-dose combination are not established from the available information.
Onset of ActionBronchodilation from indacaterol begins within 5 minutes after inhalation, with a noticeable effect within 15 minutes. The anti-inflammatory effect of mometasone develops gradually over days to weeks.
Peak Plasma TimePeak plasma concentration of indacaterol is reached approximately 15 minutes to 1 hour after inhalation. Peak plasma concentration of mometasone is reached within 1 to 2 hours. Specific data for this combination product are not established from the available information.
Duration of ActionThe bronchodilator effect of indacaterol lasts approximately 24 hours, allowing once-daily dosing. The anti-inflammatory effect of mometasone is maintained with regular daily use.

How It Works

This medicine combines two active ingredients with complementary actions. Indacaterol is a long-acting beta-2 adrenergic agonist that selectively stimulates beta-2 receptors in the smooth muscle of the airways, leading to relaxation and bronchodilation. Mometasone is a synthetic corticosteroid that binds to glucocorticoid receptors inside cells, reducing the production of inflammatory mediators and suppressing the recruitment of inflammatory cells in the airways. The combined effect is sustained airway opening and reduced inflammation, which helps prevent asthma symptoms and exacerbations.

Mechanism Steps

1
Indacaterol binds beta-2 receptors: Indacaterol selectively binds to beta-2 adrenergic receptors on airway smooth muscle cells, triggering a signaling cascade that increases cyclic AMP levels.
2
Airway smooth muscle relaxation: The rise in cyclic AMP causes the smooth muscle to relax, which widens the airways and makes breathing easier for up to 24 hours.
3
Mometasone enters cells and binds glucocorticoid receptors: Mometasone diffuses into airway cells and binds to cytoplasmic glucocorticoid receptors, forming a complex that moves into the nucleus.
4
Suppression of inflammatory gene expression: The mometasone-receptor complex inhibits the transcription of pro-inflammatory genes and increases the production of anti-inflammatory proteins, reducing airway inflammation.
5
Combined clinical effect: The simultaneous bronchodilation from indacaterol and anti-inflammatory action of mometasone lead to better asthma control, fewer symptoms, and reduced exacerbations.

💡 How to Take indamet 80 capsule

Strength: Dry powder inhaler capsule containing indacaterol 150 mcg and mometasone 80 mcg.

1Wash and dry your hands before handling the inhaler and capsules.
2Remove one capsule from the blister pack just before use; do not swallow the capsule.
3Open the inhaler device according to the manufacturer's instructions and place the capsule in the capsule chamber.
4Close the device and press the piercing button once to puncture the capsule.
5Breathe out fully away from the inhaler to empty your lungs.
6Place the mouthpiece in your mouth, seal your lips around it, and inhale deeply and steadily.
7Hold your breath for about 5 to 10 seconds, then exhale slowly.
8Remove the capsule and check if it is empty; if powder remains, repeat the inhalation.
9Rinse your mouth with water and spit it out without swallowing to prevent oral thrush.
10Close the inhaler and store it in a dry place.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one inhalation once daily, preferably at the same time each day. The dose must be individualized by a qualified clinician based on the patient's asthma severity, response to treatment, and other medical conditions. Do not exceed the recommended dose. This medicine is for maintenance therapy only and should not be used for acute symptoms.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients based on age alone. However, elderly patients may be more susceptible to cardiovascular effects and should be monitored closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is recommended for patients with renal impairment. However, use with caution in severe renal impairment as data are limited.
Hepatic ImpairmentNo specific dose adjustment is recommended for patients with mild to moderate hepatic impairment. In severe hepatic impairment, use with caution as systemic exposure may be increased. Dose must be individualized by a qualified clinician.
Maximum Daily DoseOne inhalation of indacaterol 150 mcg and mometasone 80 mcg once daily. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Grapefruit juice
Avoid
May increase drug levels by inhibiting CYP3A4.
Any food
No specific timing restriction
This medicine is inhaled and does not interact with food directly.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of indamet 80 capsule

✅ Common Side Effects

Nasopharyngitis (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.
Throat irritation (Common (1-5%))
Rinse mouth after inhalation. Consult doctor if it continues.
Cough (Common (1-5%))
Usually temporary. If cough worsens, contact your doctor.
Hoarseness of voice (Common (1-5%))
Rinse mouth and throat after each dose. Consult doctor if it persists.

🚨 Serious Side Effects

Paradoxical bronchospasm (Rare (<0.1%))
Stop using the inhaler and seek immediate medical attention if breathing worsens after inhalation.
Immediate hypersensitivity reactions (Rare (<0.1%))
Seek emergency care if you develop rash, hives, swelling of face or throat, or difficulty breathing.
Adrenal suppression (Rare (<0.1%))
Long-term high-dose use may suppress adrenal function. Consult your doctor for monitoring if you have fatigue, weakness, or low blood pressure.
Increased blood glucose (Uncommon (0.1-1%))
Monitor blood sugar if you have diabetes. Report persistent high readings to your doctor.
Hypokalemia (Rare (<0.1%))
Report muscle weakness, cramps, or palpitations to your doctor for evaluation.

⚠️ Rare Side Effects

Cardiac arrhythmias
Seek medical attention if you experience palpitations, chest pain, or fainting.
Glaucoma or cataracts
Report eye pain, blurred vision, or halos around lights to your doctor.
Oral candidiasis
Rinse mouth after each dose. Consult doctor if white patches appear in the mouth.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Propranolol Major
Furosemide Major
Phenelzine Moderate
Amitriptyline Moderate
Theophylline Minor
Prednisone Moderate
Ritonavir Major
Clarithromycin Major
Metoprolol Major

🚨 Major Interactions

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)
  • Beta-blockers (e.g., propranolol, metoprolol)
  • Non-potassium-sparing diuretics (e.g., furosemide, hydrochlorothiazide)

⚡ Moderate Interactions

  • Monoamine oxidase inhibitors and tricyclic antidepressants
  • Other inhaled corticosteroids

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, or low blood pressure when combined with this medicine. It is advisable to limit or avoid alcohol while using this inhaler.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to indacaterol, mometasone, or any component of the formulation","Acute severe asthma attack or status asthmaticus","Use as a rescue inhaler for sudden breathing problems","Children under 12 years of age (safety and efficacy not established)"]

⚠️ Warnings & Precautions

["Do not use this medicine to treat acute asthma symptoms; a short-acting rescue inhaler should be available.","Paradoxical bronchospasm may occur and can be life-threatening; discontinue and seek medical help if it occurs.","Long-term use of inhaled corticosteroids may cause adrenal suppression, especially at high doses.","Use with caution in patients with cardiovascular disorders, seizure disorders, thyroid disease, or diabetes.","Inhaled corticosteroids may increase the risk of cataracts and glaucoma; regular eye exams are advised.","Rinse mouth after each inhalation to prevent oral fungal infections.","Do not exceed the prescribed dose; excessive use may cause serious cardiac effects."]

🤱 Lactation Safety

It is not known whether indacaterol or mometasone are excreted in human breast milk. Caution is advised when using this medicine during breastfeeding. Consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose with this inhaled medicine is unlikely due to its route of administration. If excessive doses are inhaled, symptoms may include tachycardia, tremor, headache, and hypokalemia. Treatment is supportive and symptomatic. In case of accidental ingestion of capsules, seek medical attention. Contact a poison control center or emergency department if severe symptoms occur.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always rinse your mouth with water after inhaling this medicine to reduce the risk of oral fungal infections and hoarseness. Do not swallow the capsule; it is designed to be pierced or inhaled through the device according to the manufacturer's instructions. Keep the inhaler and capsules dry and store them in the original packaging. Do not use this medicine to relieve sudden asthma attacks; keep a short-acting rescue inhaler available at all times. Inform your doctor if you have heart problems, thyroid disorders, diabetes, or a history of glaucoma or cataracts. Do not stop this medicine abruptly without medical advice, as stopping suddenly can worsen asthma control. Regular follow-up with your doctor is important to assess lung function and adjust treatment if needed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular effects of beta-2 agonists. Monitor heart rate and blood pressure regularly. Also, the risk of cataracts and glaucoma increases with long-term inhaled corticosteroid use.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss your asthma medications with your doctor. Uncontrolled asthma poses risks to both mother and baby. This medicine should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

Inform your anesthesiologist and surgeon about this medicine before surgery. Inhaled corticosteroids may need to be continued perioperatively to prevent adrenal crisis. Follow your doctor's instructions regarding dosing around surgery.

🦷 Dental Procedures

Inhaled corticosteroids can increase the risk of oral candidiasis. Inform your dentist about this medicine before dental procedures. Rinsing with water after inhalation helps prevent oral fungal infections.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your breathing.
🥗
Avoid known asthma triggers such as dust, smoke, and pollen.
😴
Practice breathing exercises like pursed-lip breathing to improve lung function.
💧
Get regular physical activity as tolerated to improve cardiovascular health.
🧘
Ensure adequate sleep and manage stress to reduce asthma flare-ups.
🌞
Stay up to date with vaccinations, including influenza and COVID-19.

🏋️ Exercise Considerations

Exercise is generally encouraged, but if you experience exercise-induced bronchoconstriction, use your rescue inhaler as prescribed before exercising. Warm up gradually and avoid exercising in cold, dry air or high pollution areas.

🥗 Diet Recommendations

Include plenty of fruits and vegetables rich in antioxidants.
Choose whole grains and lean proteins.
Limit processed foods and added sugars.
Stay well hydrated to keep airways moist.
Avoid foods that trigger acid reflux, as it can worsen asthma.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremor in some patients. Avoid driving or operating heavy machinery until you know how it affects you. Most patients can continue their daily activities with improved breathing.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as paradoxical bronchospasm or severe allergic reactions, stop immediately and seek medical help. Your doctor may adjust or discontinue the medicine based on your response and side effects.

📅 Long-Term Use Effects

Long-term use of this medicine may be associated with adrenal suppression, increased risk of cataracts and glaucoma, and reduced bone mineral density. Regular monitoring of lung function, eye health, and adrenal function is recommended. Do not stop the medicine without medical advice, as stopping suddenly can worsen asthma control.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Reducing exposure to asthma triggers can complement medical therapy.

Evidence: Well-established
Immunotherapy

Allergy shots may help reduce asthma symptoms in allergic patients.

Evidence: Moderate
Breathing exercises

Techniques like Buteyko breathing may improve symptom control.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Inhaled corticosteroids may slightly increase the risk of respiratory infections. Ensure you are up to date with influenza and pneumococcal vaccinations as advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep capsules in the original blister pack until use

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight and moisture

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid extreme temperatures in checked baggage. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the same interval as at home, or consult your doctor for adjustment. Check customs regulations for carrying prescription inhalers.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with moderate persistent asthma
She was prescribed this medicine once daily after her asthma was not controlled with a lower-dose inhaled steroid. Within four weeks, her nighttime awakenings decreased, and she could exercise without wheezing. She learned to rinse her mouth after each dose and kept her rescue inhaler handy.
💡 Lesson: Consistent daily use and proper inhalation technique are key to achieving asthma control with this medicine.
👤 A 50-year-old man with a history of diabetes and asthma
He started this medicine and noticed mild increases in his blood sugar levels. His doctor monitored his glucose closely and adjusted his diabetes medication. His asthma symptoms improved significantly, and he remained on the inhaler with regular follow-up.
💡 Lesson: Patients with diabetes should monitor blood sugar closely when using this medicine, as inhaled corticosteroids can affect glucose levels.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The bronchodilator effect starts within minutes, but the full anti-inflammatory benefits may take several days to weeks of regular use.

Q: Can I use this medicine during an asthma attack?

A: No, this medicine is for maintenance only. Use a short-acting rescue inhaler for sudden symptoms.

Q: Is it safe to use this medicine during pregnancy?

A: Consult your doctor. The benefits of asthma control must be weighed against potential risks to the fetus.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if less than 12 hours have passed. If more than 12 hours, skip it and continue your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood sugar levels?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can be used as a rescue inhaler for sudden asthma attacks.
    Fact: This medicine is a maintenance therapy and should not be used for acute symptoms. A short-acting rescue inhaler is needed for sudden attacks.
  • Myth: Inhaled steroids are dangerous and should be avoided.
    Fact: Inhaled corticosteroids are safe and effective for controlling airway inflammation when used as prescribed. They are the cornerstone of asthma management.
  • Myth: Once symptoms improve, the medicine can be stopped.
    Fact: Asthma is a chronic condition. Stopping this medicine without medical advice can lead to worsening symptoms and exacerbations.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Indacaterol + Mometasone)","class":"LABA + ICS","frequency":"Once daily","primary_use":"Asthma maintenance"},{"medicine":"Mometasone + Formoterol","class":"ICS + LABA","frequency":"Twice daily","primary_use":"Asthma maintenance"},{"medicine":"Budesonide + Formoterol","class":"ICS + LABA","frequency":"Twice daily or as needed","primary_use":"Asthma and COPD"}]

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