inclo p 100mg/200mg tablet - Aceclofenac (100mg) + Paracetamol (200mg) medicine

Inclo P 100mg/200mg Tablet: Complete Information

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🏭 Invomed Cotab Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, NSAIDs like Aceclofenac are generally avoided during pregnancy, especially in the third trimester, due to risk of premature closure of ductus arteriosus and other complications. Paracetamol is generally considered safe in pregnancy when used at recommended doses for short periods. Consult your doctor before using this medicine. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is inclo p 100mg/200mg tablet used for?

This medicine is a combination of Aceclofenac and Paracetamol used for relief of pain and inflammation in conditions like arthritis, musculoskeletal injuries, and dental pain. It works by reducing prostaglandins that cause pain and swelling. Take it with food to avoid stomach upset and do not exceed the prescribed dose.

  • Generic Name: Aceclofenac (100mg) + Paracetamol (200mg)
  • Manufacturer: Invomed Cotab Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 inclo p 100mg/200mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटामिनोफेन और एसिक्लोफेनैक का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह गठिया, मांसपेशियों में खिंचाव, दांत दर्द और मासिक धर्म के दर्द में प्रभावी है। इसे भोजन के साथ लें ताकि पेट में जलन न हो।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, एलर्जी प्रतिक्रिया, लिवर और किडनी की समस्या हो सकती है। यदि कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन के साथ लें। शराब का सेवन न करें। यदि आपको पेट अल्सर, किडनी, लिवर या हृदय रोग है तो डॉक्टर को बताएं। गर्भवती महिलाएं बिना डॉक्टर की सलाह के इसका सेवन न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 inclo p 100mg/200mg tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Provides relief from pain due to sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of mild to moderate post-operative pain.","evidence":"Moderate"},{"condition":"Dental pain","description":"Effective for relieving dental pain and inflammation after dental procedures.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Fever","description":"Paracetamol component may reduce fever, but this combination is not primarily indicated for fever alone.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation associated with musculoskeletal conditions.

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal pain, Dental pain, Dysmenorrhea

📋 Drug Information

Generic Name(s)Aceclofenac (100mg) + Paracetamol (200mg)
Brand Nameinclo p 100mg/200mg tablet
ManufacturerInvomed Cotab Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the recommended dose or duration without consulting your doctor.
3
Avoid alcohol while taking this medicine to prevent liver and stomach problems.
4
If you have a history of stomach ulcers, kidney, liver, or heart disease, inform your doctor before taking this medicine.
5
Do not take other pain relievers or NSAIDs concurrently without medical advice.
6
Consult your doctor if pain persists beyond 7 days or worsens.
7
Report any unusual bleeding, bruising, or signs of infection immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Dental pain
This medicine can relieve dental pain and inflammation.
Likely Use
✅
Menstrual cramps
This medicine can relieve menstrual pain.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAceclofenac is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 1.5 to 2 hours. Paracetamol is also rapidly absorbed from the gastrointestinal tract, with peak levels within 30 to 60 minutes. Food may delay absorption slightly but does not significantly affect the extent of absorption.
DistributionAceclofenac is highly protein-bound (greater than 99%) and distributes well into synovial fluid. Paracetamol distributes widely throughout body tissues, with a volume of distribution of about 0.9 L/kg.
Protein BindingAceclofenac: >99% bound to plasma proteins. Paracetamol: approximately 10-25% bound to plasma proteins.
MetabolismAceclofenac is metabolized in the liver primarily by CYP2C9 to inactive metabolites. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeAceclofenac: approximately 4 hours. Paracetamol: 2 to 3 hours.
ExcretionAceclofenac metabolites are excreted mainly in urine and bile. Paracetamol metabolites are excreted in urine.
BioavailabilityAceclofenac: approximately 80-100%. Paracetamol: approximately 80-90%.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimeAceclofenac: 1.5 to 2 hours. Paracetamol: 0.5 to 1 hour.
Duration of ActionApproximately 4 to 6 hours, necessitating dosing every 6 to 8 hours as needed.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, resulting in analgesia and antipyresis. Together, they provide effective relief from pain and inflammation.

Mechanism Steps

1
Inhibition of COX enzymes: Aceclofenac inhibits cyclooxygenase enzymes, reducing prostaglandin production.
2
Reduced inflammation: Decreased prostaglandins lead to less vasodilation, edema, and pain sensitization.
3
Central analgesia: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis and modulate pain perception.
4
Antipyretic effect: Paracetamol acts on the hypothalamus to reduce fever by promoting heat loss.

💡 How to Take inclo p 100mg/200mg tablet

Strength: Tablet containing Aceclofenac 100 mg and Paracetamol 200 mg.

1Take the tablet orally with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed dosing schedule.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally two to three times daily, preferably after meals. The maximum daily dose should not exceed three tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use the lowest effective dose for the shortest duration. Monitor kidney function and for signs of bleeding.
Renal ImpairmentUse with caution in patients with mild to moderate renal impairment. Avoid in severe renal impairment (creatinine clearance <30 mL/min). Dose adjustment may be required. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. Avoid in severe hepatic impairment. Dose adjustment may be required. Consult your doctor.
Maximum Daily DoseThe maximum daily dose is 3 tablets (300 mg Aceclofenac + 600 mg Paracetamol) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver damage.
Caffeine
Limit
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of inclo p 100mg/200mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated. If severe or persistent, seek medical advice.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If pain worsens, contact your doctor.
Indigestion (Common (5-10%))
Take with meals. Antacids may help, but consult your doctor first.
Headache (Common (5-10%))
Rest and stay hydrated. If headache persists, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Report persistent stomach pain or indigestion to your doctor immediately.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.
Liver toxicity (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor.
Cardiovascular events (heart attack, stroke) (Rare (<0.1%))
Seek immediate care for chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Blood disorders (e.g., agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor.
Severe skin reactions (e.g., Stevens-Johnson syndrome)
Seek immediate medical attention for rash, blisters, or peeling skin.
Aseptic meningitis
Seek medical care for severe headache, stiff neck, and fever.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors/ARBs Major
Diuretics Major
SSRIs Moderate
Anticonvulsants Moderate
Probenecid Moderate

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids
  • Methotrexate
  • Lithium
  • ACE inhibitors and ARBs
  • Diuretics

⚡ Moderate Interactions

  • Antihypertensives (e.g., beta-blockers, calcium channel blockers)
  • SSRIs
  • Anticonvulsants (e.g., phenytoin, carbamazepine)
  • Probenecid

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity, especially with paracetamol. It can also enhance drowsiness and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Aceclofenac, Paracetamol, or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney impairment (e.g., creatinine clearance

⚠️ Warnings & Precautions

["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Do not exceed recommended dose or duration.","Use with caution in elderly patients.","Monitor for signs of gastrointestinal bleeding.","Use with caution in patients with cardiovascular risk factors.","Consult doctor before use in patients with kidney or liver disease.","Do not use concurrently with other NSAIDs.","May cause dizziness; avoid driving if affected.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Aceclofenac and Paracetamol are excreted in breast milk in small amounts. Paracetamol is generally considered safe during breastfeeding. Aceclofenac should be used with caution as its effects on the nursing infant are not well established. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding due to Aceclofenac. Symptoms of overdose include nausea, vomiting, abdominal pain, drowsiness, and confusion. Seek immediate medical attention. Treatment includes gastric lavage, activated charcoal, and administration of N-acetylcysteine for paracetamol toxicity. Supportive care for NSAID toxicity may be required.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine, as it can increase the risk of gastrointestinal bleeding and liver damage. Do not use this medicine for more than 7 days without consulting your doctor. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma, inform your doctor before taking this medicine. Do not take other pain relievers or NSAIDs concurrently without medical advice. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are generally avoided during pregnancy.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but consult your surgeon before taking it, especially if you are on blood thinners or have kidney problems.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Avoid smoking and limit alcohol.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain while taking this medicine. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Eat plenty of fruits and vegetables

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset; take with food.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or if your pain does not improve within 7 days. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is advised. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot/cold therapy

May help reduce pain and inflammation.

Evidence: Moderate
Acupuncture

Some evidence for pain relief in chronic conditions.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, if you are scheduled for vaccination, inform your doctor about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old retired teacher with rheumatoid arthritis
Used this medicine for flare-ups. Experienced relief within an hour but also mild nausea. Learned to take it after meals and to avoid alcohol. Regular monitoring of kidney function was advised.
💡 Lesson: Taking with food and monitoring for side effects are key to safe use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as it may increase the risk of side effects.

Q: Can I take it during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy, especially in the third trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: Inclo P is a steroid.
    Fact: Inclo P is a combination of an NSAID and paracetamol, not a steroid.
  • Myth: Inclo P can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset.
  • Myth: Inclo P is safe to take with other painkillers.
    Fact: Taking it with other NSAIDs can increase the risk of side effects. Consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 100 mg + Paracetamol 200 mg tablet (various manufacturers)

Brand Alternatives

  • Inclo P 100mg/200mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Inclo P 100mg/200mg","composition":"Aceclofenac 100 mg + Paracetamol 200 mg","onset":"30-60 minutes","duration":"4-6 hours","common_side_effects":"Nausea, stomach pain, dizziness"},{"medicine":"Aceclofenac 100 mg + Paracetamol 325 mg","composition":"Aceclofenac 100 mg + Paracetamol 325 mg","onset":"30-60 minutes","duration":"4-6 hours","common_side_effects":"Nausea, stomach pain, dizziness"},{"medicine":"Diclofenac 50 mg + Paracetamol 325 mg","composition":"Diclofenac 50 mg + Paracetamol 325 mg","onset":"30-60 minutes","duration":"4-6 hours","common_side_effects":"Nausea, stomach pain, dizziness"}]

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