Ivabrad OD 15mg Tablet (Ivabradine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fainting or severe dizziness
- Very slow pulse (less than 50 beats per minute)
- Chest pain that is new or worsening
- Shortness of breath or swelling in legs
- Irregular or rapid heartbeat
- Yellowing of skin or eyes
- Severe allergic reaction (rash, swelling, difficulty breathing)
If experiencing severe symptoms, call emergency services immediately.
What is inapure er 15 tablet used for?
This medicine contains Ivabradine 15 mg, which is used to treat stable angina and chronic heart failure by lowering heart rate. It is taken orally, usually twice daily, and must be prescribed by a doctor.
- Generic Name: Ivabradine (15mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 inapure er 15 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा इवाब्राडीन 15 मिलीग्राम टैबलेट है, जिसका उपयोग स्थिर एंजाइना (दिल की धमनियों में रक्त प्रवाह कम होने के कारण सीने में दर्द) और कुछ प्रकार के दिल की विफलता के इलाज के लिए किया जाता है। यह दिल की धड़कन को धीमा करके दिल पर दबाव कम करती है। यह दवा केवल डॉक्टर के पर्चे पर ही ली जानी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में दृष्टि में चमक (फॉस्फीन), धुंधली दृष्टि, सिरदर्द, चक्कर आना और दिल की धड़कन धीमी होना शामिल हैं। गंभीर दुष्प्रभावों में बहुत धीमी हृदय गति, हृदय रुकावट, और दिल की विफलता का बिगड़ना शामिल है। यदि आपको बेहोशी, अत्यधिक थकान, या दृष्टि में लगातार बदलाव महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप डोज न बदलें और न ही दवा बंद करें। इस दवा के साथ अंगूर और अंगूर का जूस न लें। यदि आपको गुर्दे या यकृत की समस्या है, तो डॉक्टर को बताएं। गाड़ी चलाते या मशीन चलाते समय सावधानी बरतें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 inapure er 15 tablet Uses & Benefits
[{"condition":"Stable angina pectoris","description":"Used to reduce the frequency of angina attacks in adults who cannot tolerate or are not adequately controlled by beta-blockers.","evidence":"Well-established"},{"condition":"Chronic heart failure","description":"Used in selected patients with chronic heart failure to reduce heart rate and lower the risk of hospitalisation.","evidence":"Well-established"},{"condition":"Inappropriate sinus tachycardia","description":"Sometimes used off-label to control abnormally fast heart rate originating from the sinus node.","evidence":"Limited"}]
Off-label uses: [{"condition":"Inappropriate sinus tachycardia","description":"May be prescribed off-label to reduce heart rate in patients with this condition.","evidence":"Limited"},{"condition":"Postural orthostatic tachycardia syndrome (POTS)","description":"Occasionally used off-label to manage heart rate in POTS, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Stable angina pectoris
Also treats: Chronic heart failure, Inappropriate sinus tachycardia
📋 Drug Information
| Generic Name(s) | Ivabradine (15mg) |
| Brand Name | inapure er 15 tablet |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | I F sodium channel (sinoatrial node) current blockers |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine selectively inhibits the funny current (If) in the sinoatrial node of the heart. The funny current is a mixed sodium-potassium inward current that helps generate the spontaneous electrical activity of the heart's pacemaker. By blocking this current, the medicine slows the rate at which the sinoatrial node fires, thereby reducing heart rate. This effect is use-dependent, meaning it works more when the heart rate is high. Unlike beta-blockers, it does not affect blood pressure, myocardial contractility, or coronary vasodilation.
Mechanism Steps
💡 How to Take inapure er 15 tablet
Strength: Ivabradine 15 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual starting dose is 5 mg twice daily, which may be increased to 7.5 mg twice daily after 3-4 weeks based on heart rate and symptoms. The maximum dose is 7.5 mg twice daily. For patients with heart failure, the starting dose is 5 mg twice daily, adjusted according to heart rate. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but they may be more sensitive to heart rate-lowering effects. Start with a lower dose and monitor closely. |
| Renal Impairment | No dose adjustment is needed for mild to moderate renal impairment. In severe renal impairment (creatinine clearance <15 mL/min), use with caution and monitor closely. |
| Hepatic Impairment | No dose adjustment is needed for mild hepatic impairment. In moderate hepatic impairment, use with caution. In severe hepatic impairment, contraindicated. |
| Maximum Daily Dose | 15 mg per day (7.5 mg twice daily). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of inapure er 15 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Rifampicin | Major | |
| Beta-blockers | Major | |
| Digoxin | Moderate | |
| Diltiazem | Moderate | |
| Verapamil | Moderate | |
| Amiodarone | Major | |
| Grapefruit juice | Minor | |
| St. John's wort | Major |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir)
- Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, St. John's wort)
- Other heart-rate-lowering drugs (e.g., beta-blockers, digoxin, amiodarone)
⚡ Moderate Interactions
- Moderate CYP3A4 inhibitors (e.g., diltiazem, verapamil, grapefruit juice)
- QT-prolonging drugs (e.g., sotalol, quinidine, some antipsychotics)
🍷 Alcohol Interaction
Alcohol may worsen dizziness and low blood pressure. It is advisable to avoid or limit alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia (heart rate
⚠️ Warnings & Precautions
["Do not stop this medicine suddenly without consulting your doctor.","Avoid grapefruit and grapefruit juice.","Use caution when driving or operating machinery until you know how this medicine affects you.","Inform your doctor if you have kidney or liver problems.","Tell your doctor about all other medicines you are taking, especially those that affect heart rate or CYP3A4.","This medicine is not for use in children unless prescribed by a specialist.","Elderly patients may be more sensitive to heart rate-lowering effects."]
🤱 Lactation Safety
Not established from the available information. Ivabradine may pass into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe bradycardia, hypotension, and dizziness. Seek immediate medical attention. Treatment is supportive and may include intravenous fluids, atropine, or temporary pacing if needed. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop it on your own, as sudden stopping can worsen angina or heart failure. Avoid grapefruit and grapefruit juice while taking this medicine, as it can increase the amount of medicine in your body. Inform your doctor if you have kidney or liver problems, low blood pressure, or a history of heart rhythm disorders. Use caution while driving or operating machinery, especially when you start treatment, because this medicine can cause temporary visual symptoms or dizziness. Do not take this medicine if you are pregnant or planning pregnancy without consulting your doctor. Keep all follow-up appointments for heart rate, blood pressure, and ECG monitoring.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to heart rate-lowering effects. Start with a lower dose and monitor heart rate and blood pressure closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. This medicine is not recommended during pregnancy unless clearly needed. Effective contraception should be discussed.
🏥 Post-Surgery Considerations
Inform your surgeon and anaesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery as advised by your doctor.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are usually needed, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until your doctor says it is safe. Start with light activities and gradually increase. Stop immediately if you experience chest pain, dizziness, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or visual symptoms, especially when you start treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most patients can continue their normal activities with caution.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects like severe bradycardia, fainting, or allergic reactions, seek immediate medical attention and follow your doctor's advice on stopping.
📅 Long-Term Use Effects
Long-term use may require regular monitoring of heart rate, blood pressure, and ECG. Some patients may develop tolerance or worsening of heart failure. Periodic review of liver and kidney function is advised. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another class of heart rate-lowering medicines commonly used for angina and heart failure.
Evidence: Well-establishedCan be used for angina if beta-blockers are not suitable.
Evidence: Well-establishedDiet, exercise, and stress management can complement medical therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting dosing times. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Heart rate reduction begins within 1-2 hours, but full benefits for angina may take a few weeks.
A: No, do not stop without consulting your doctor. Stopping suddenly can worsen your condition.
A: Take it as soon as you remember if less than half the dosing interval has passed. Otherwise, skip it and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for inapure er 15 tablet
View AllAlternative brands with exact same active ingredient:
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irban od 15 tablet prGlenmark Pharmaceuticals Ltd ₹281.25 30.2% CHEAPER
-
ivapace 15mg tablet srCorona Remedies Pvt Ltd ₹281.25 30.2% CHEAPER
-
ivaniche 15mg tabletAlniche Life Sciences Pvt Ltd ₹450.00 11.6% COSTLIER
-
ivabrad od 15mg tabletLupin Ltd ₹494.70 22.7% COSTLIER
-
ivabeat od 15mg tablet erCipla Ltd ₹543.75 34.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of chest pain.
Fact: It is specifically for stable angina and certain heart failure cases, not for all chest pain. - Myth: This medicine can be stopped once symptoms improve.
Fact: It should not be stopped without consulting your doctor, as it can worsen your condition. - Myth: This medicine is a blood thinner.
Fact: It is not a blood thinner; it works by lowering heart rate.
🔄 Alternative Options
Generic Alternatives
- Ivabradine 15 mg tablet
Brand Alternatives
- Ivabrad OD 15mg Tablet