imnit 60mg tablet - Isosorbide Mononitrate (60mg) medicine

Imdur 60mg Tablet PR: Comprehensive Medicine Guide

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🏭 Dr Reddy's Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for angina prevention.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain that does not go away with rest or usual medication
  • Fainting or loss of consciousness
  • Bluish discoloration of lips, skin, or nails
  • Severe dizziness or lightheadedness
  • Sudden swelling of face, lips, or throat
  • Rapid or irregular heartbeat
  • Shortness of breath

If experiencing severe symptoms, call emergency services immediately.

What is imnit 60mg tablet used for?

This medicine is a nitrate used to prevent angina attacks. It works by relaxing blood vessels to improve blood flow to the heart. It is not for immediate relief of an acute attack.

  • Generic Name: Isosorbide Mononitrate (60mg)
  • Manufacturer: Dr Reddy's Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 imnit 60mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एंजाइना (सीने में दर्द) के हमलों को रोकने के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर हृदय तक रक्त का प्रवाह बढ़ाती है और हृदय पर दबाव कम करती है। यह दवा तीव्र एंजाइना हमले के तत्काल उपचार के लिए नहीं है।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा और मतली शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर निम्न रक्तचाप, बेहोशी और मेथेमोग्लोबिनेमिया शामिल हो सकते हैं। यदि आपको असामान्य लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें। शराब से बचें। सिल्डेनाफिल जैसी दवाओं के साथ इसका सेवन न करें। उठते-बैठते समय धीरे-धीरे उठें ताकि चक्कर न आएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 imnit 60mg tablet Uses & Benefits

[{"condition":"Prevention of angina pectoris","description":"This medicine is used for long-term prevention of angina attacks in patients with coronary artery disease.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"It helps reduce the frequency and severity of angina episodes when used regularly.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Heart failure with preserved ejection fraction","description":"Sometimes used off-label to reduce symptoms, but evidence is limited.","evidence":"Limited"},{"condition":"Esophageal spasm","description":"Occasionally used off-label to relieve esophageal spasm, but this is not a standard use.","evidence":"Limited"}]

Primary treatment for: Angina pectoris

Also treats: Coronary artery disease, Chronic stable angina

📋 Drug Information

Generic Name(s)Isosorbide Mononitrate (60mg)
Brand Nameimnit 60mg tablet
ManufacturerDr Reddy's Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassNO Donors
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent levels.
2
Do not use this medicine for immediate relief of an acute angina attack; use a fast-acting nitrate instead.
3
Inform your doctor if you experience frequent headaches, as the dose may need adjustment.
4
Avoid alcohol while taking this medicine to prevent severe dizziness and low blood pressure.
5
Do not stop this medicine suddenly without consulting your doctor, as it can worsen angina.
6
Keep a record of your angina attacks and share it with your doctor at each visit.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chest pain (angina)
This medicine is commonly prescribed to prevent angina attacks.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
Headache is a side effect, not a reason to use this medicine.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. The extended-release formulation provides a slow release of the drug over several hours.
DistributionIsosorbide mononitrate is widely distributed in the body. It has a volume of distribution of approximately 0.6 L/kg.
Protein BindingLess than 5% of isosorbide mononitrate is bound to plasma proteins.
MetabolismIsosorbide mononitrate is metabolized in the liver, primarily by denitration. It does not undergo significant first-pass metabolism.
Half-LifeThe elimination half-life of isosorbide mononitrate is approximately 5 hours.
ExcretionThis medicine is excreted mainly by the kidneys as metabolites. About 2% is excreted unchanged in urine.
BioavailabilityThe oral bioavailability of isosorbide mononitrate is nearly 100% because it avoids first-pass metabolism.
Onset of ActionThe onset of action for angina prevention is usually within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached in about 1 to 2 hours after oral administration of the immediate-release form. For the extended-release form, peak levels occur later.
Duration of ActionThe duration of action is approximately 12 to 24 hours depending on the formulation and dose.

How It Works

This medicine works by releasing nitric oxide in the body. Nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic GMP levels in smooth muscle cells. This leads to relaxation of vascular smooth muscle, especially in veins. The result is dilation of blood vessels, reduced preload and afterload on the heart, and improved blood flow to the heart muscle. This helps prevent angina attacks.

Mechanism Steps

1
Release of nitric oxide: This medicine is metabolized in the body to release nitric oxide, a powerful vasodilator.
2
Activation of guanylate cyclase: Nitric oxide activates the enzyme guanylate cyclase in smooth muscle cells.
3
Increase in cyclic GMP: Activation of guanylate cyclase leads to increased levels of cyclic GMP.
4
Smooth muscle relaxation: Increased cyclic GMP causes relaxation of vascular smooth muscle, leading to vasodilation.
5
Reduced cardiac workload: Vasodilation reduces preload and afterload, decreasing the heart's oxygen demand and helping prevent angina.

💡 How to Take imnit 60mg tablet

Strength: This medicine is available as a 60 mg extended-release tablet.

1Take this medicine by mouth with a glass of water.
2Swallow the tablet whole; do not crush, chew, or break it.
3Take it at the same time each day.
4Follow your doctor's instructions about whether to take it with or without food.
5Do not stop taking this medicine suddenly without talking to your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 30 mg to 60 mg once daily, but the exact dose depends on the indication and patient response. Your doctor will individualize the dose based on your condition, age, and other factors. Do not change the dose without consulting your doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. Use with caution and monitor.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and monitor.
Maximum Daily DoseThe maximum recommended daily dose is 120 mg, but this should be determined by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit juice
Avoid
May increase drug levels and side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of imnit 60mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult your doctor if it persists or is severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid driving if dizzy.
Flushing (Common (1-5%))
Usually harmless. Consult doctor if bothersome.
Nausea (Common (1-5%))
Take with food if it upsets your stomach.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you feel faint, have blurred vision, or cold clammy skin.
Syncope (Rare (<0.1%))
Lie down and call for help if you faint or feel like you might faint.
Methemoglobinemia (Very rare (<0.01%))
Seek emergency care if you have bluish lips, skin, or nails, shortness of breath, or confusion.

⚠️ Rare Side Effects

Allergic reactions
Seek immediate medical help if you develop rash, itching, swelling, or difficulty breathing.
Exfoliative dermatitis
Consult a doctor if you notice peeling or blistering skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Sildenafil Major
Tadalafil Major
Vardenafil Major
Riociguat Major
Alcohol Moderate
Beta-blockers Moderate
Calcium channel blockers Moderate
Diuretics Moderate
NSAIDs Minor
Grapefruit juice Minor

🚨 Major Interactions

  • Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
  • Riociguat

⚡ Moderate Interactions

  • Alcohol
  • Antihypertensives (e.g., beta-blockers, calcium channel blockers)
  • Diuretics

🍷 Alcohol Interaction

Alcohol can increase the blood pressure-lowering effect of this medicine and lead to severe dizziness, fainting, and low blood pressure. It is best to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to isosorbide mononitrate or other nitrates","Concomitant use with phosphodiesterase-5 inhibitors","Severe hypotension","Increased intracranial pressure","Severe anemia","Constrictive pericarditis","Hypertrophic obstructive cardiomyopathy"]

⚠️ Warnings & Precautions

["Do not use for acute angina attacks; use a fast-acting nitrate for immediate relief.","Tolerance to the effects can develop with continuous use; a nitrate-free interval is often recommended.","Avoid abrupt discontinuation as it may worsen angina.","Use with caution in patients with low blood pressure or dehydration.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose can cause severe hypotension, headache, dizziness, and methemoglobinemia. Seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, vasopressors, and methylene blue for methemoglobinemia.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly because this can worsen angina. Avoid alcohol because it can increase dizziness and low blood pressure. Do not take erectile dysfunction medicines such as sildenafil, tadalafil, or vardenafil while using this medicine. Rise slowly from sitting or lying positions to prevent dizziness. Keep a record of your angina attacks and inform your doctor if they become more frequent or severe. Store this medicine at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. They should start with a lower dose and be monitored closely for dizziness and falls.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with medications used during surgery and affect blood pressure. Your doctor may advise temporary discontinuation.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dizziness or low blood pressure during dental procedures. Your dentist may take precautions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the workload on your heart.
🥗
Engage in regular physical activity as advised by your doctor.
😴
Avoid smoking and limit alcohol consumption.
💧
Eat a heart-healthy diet rich in fruits, vegetables, and whole grains.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep to support heart health.

🏋️ Exercise Considerations

Regular exercise is beneficial for heart health, but avoid strenuous activities that trigger angina. Consult your doctor before starting any new exercise program. If you experience chest pain during exercise, stop immediately and rest.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed and high-fat foods.
Limit salt to help control blood pressure.
Stay well hydrated unless advised otherwise.
Avoid excessive caffeine, which can trigger palpitations.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or lightheadedness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities, but take precautions when rising from sitting or lying positions.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Abrupt discontinuation can worsen angina. Your doctor may adjust or stop the medicine based on your condition and response to treatment.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, where the medicine becomes less effective. To prevent this, doctors often recommend a nitrate-free interval of 10 to 12 hours each day. Regular monitoring of blood pressure and angina symptoms is important. Do not stop the medicine without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Heart-healthy diet, exercise, and stress management can complement medicine.

Evidence: Well-established
Other antianginal medicines

Beta-blockers, calcium channel blockers, or ranolazine may be alternatives or add-ons.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Keep enough supply for your trip and carry it in your hand luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with chronic stable angina
He was prescribed this medicine to prevent angina attacks. After starting treatment, he noticed fewer episodes of chest pain during his morning walks. He experienced mild headaches initially, which improved after a few days. He learned to take the medicine at the same time every day and avoided alcohol.
💡 Lesson: Consistent daily use and avoiding alcohol help control angina effectively.
👤 A 65-year-old woman with a history of heart disease
She was started on this medicine after experiencing frequent angina. She was advised not to take her erectile dysfunction medicine (which her husband used) and to rise slowly from bed to avoid dizziness. She found that keeping a diary of her angina attacks helped her doctor adjust her treatment.
💡 Lesson: Knowing and avoiding dangerous interactions and monitoring symptoms improves safety and outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 30 to 60 minutes, but its full preventive effect may take a few days to develop.

Q: Can I take this medicine if I have diabetes?

A: Yes, but inform your doctor about all your medicines and conditions. Your doctor will decide if it is safe for you.

Q: What should I do if I experience a headache?

A: Headache is common when starting this medicine. It often improves with continued use. If it is severe or persistent, consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for imnit 60mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for immediate relief of an angina attack.
    Fact: This medicine is for prevention only. For immediate relief, use a fast-acting nitrate as prescribed.
  • Myth: It is safe to take erectile dysfunction medicines with this medicine.
    Fact: Combining this medicine with erectile dysfunction medicines can cause dangerous low blood pressure and is contraindicated.

🔄 Alternative Options

Generic Alternatives

  • Isosorbide mononitrate 60 mg extended-release tablets

Brand Alternatives

  • Imdur 60 mg tablet PR

📊 Comparison with Similar Medicines

[{"medicine":"Isosorbide mononitrate","class":"Nitrate","primary_use":"Prevention of angina","route":"Oral"},{"medicine":"Isosorbide dinitrate","class":"Nitrate","primary_use":"Prevention and treatment of angina","route":"Oral, sublingual"},{"medicine":"Nitroglycerin","class":"Nitrate","primary_use":"Acute angina relief","route":"Sublingual, transdermal, intravenous"}]

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