Dimip 50mg Tablet (Imipramine): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Seizures
- Suicidal thoughts or behavior
- Yellowing of skin or eyes
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Confusion or hallucinations
If experiencing severe symptoms, call emergency services immediately.
What is imipres 50mg tablet used for?
Imipramine is a tricyclic antidepressant used to treat depression, panic disorder, and bedwetting in children. It works by increasing serotonin and norepinephrine in the brain. It is available as a 50mg tablet and is taken orally. Common side effects include dry mouth, constipation, and drowsiness. It should not be stopped abruptly.
- Generic Name: Imipramine (50mg)
- Manufacturer: Ryon Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 imipres 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा इमिप्रामाइन नामक तत्व से बनी है, जो एक ट्राइसाइक्लिक एंटीडिप्रेसेंट है। इसका उपयोग अवसाद (डिप्रेशन), पैनिक डिसऑर्डर, और बच्चों में बेडवेटिंग के इलाज के लिए किया जाता है। यह मस्तिष्क में सेरोटोनिन और नॉरएपिनेफ्रिन के स्तर को बढ़ाकर मूड को बेहतर बनाती है। यह 50 मिलीग्राम की गोली के रूप में उपलब्ध है और मुंह से ली जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुंह सूखना, कब्ज, धुंधली दृष्टि, नींद आना, चक्कर आना और वजन बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन, गंभीर निम्न रक्तचाप, दौरे और एलर्जी प्रतिक्रियाएं हो सकती हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अचानक बंद न करें, इससे withdrawal symptoms हो सकते हैं। शराब और अन्य नींद लाने वाली दवाओं से बचें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं, विशेष रूप से MAO inhibitors। बच्चों की पहुंच से दूर रखें।
💊 imipres 50mg tablet Uses & Benefits
[{"condition":"Major depressive disorder","description":"This medicine is used to treat symptoms of depression such as persistent sadness, loss of interest, and fatigue.","evidence":"Well-established"},{"condition":"Panic disorder","description":"It can help reduce the frequency and severity of panic attacks.","evidence":"Moderate"},{"condition":"Chronic pain","description":"Sometimes prescribed for neuropathic pain and other chronic pain conditions.","evidence":"Limited"},{"condition":"Nocturnal enuresis (bedwetting) in children","description":"May be used short-term to treat bedwetting in children over 6 years old.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes used to prevent migraines, though not FDA-approved for this purpose.","evidence":"Limited"},{"condition":"Attention deficit hyperactivity disorder (ADHD)","description":"Rarely used as an alternative when other treatments fail.","evidence":"Limited"}]
Primary treatment for: Major depressive disorder
Also treats: Panic disorder, Nocturnal enuresis, Chronic pain
📋 Drug Information
| Generic Name(s) | Imipramine (50mg) |
| Brand Name | imipres 50mg tablet |
| Manufacturer | Ryon Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Tricyclic antidepressants |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Imipramine works by inhibiting the reuptake of serotonin and norepinephrine in the brain, increasing their availability in the synaptic cleft. This leads to enhanced neurotransmission and improvement in mood. It also has anticholinergic, antihistaminic, and alpha-adrenergic blocking effects, which contribute to its side effect profile.
Mechanism Steps
💡 How to Take imipres 50mg tablet
Strength: 50mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose for depression is 25-50 mg once daily, gradually increased to 100-150 mg per day in divided doses. For panic disorder, doses may be lower. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to side effects. Start with lower doses (e.g., 10-25 mg at bedtime) and titrate slowly. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in renal impairment. Dose adjustment may be necessary. Consult a clinician. |
| Hepatic Impairment | Use with caution in hepatic impairment. Dose reduction may be required. Consult a clinician. |
| Maximum Daily Dose | Up to 150 mg per day for outpatients; up to 300 mg per day for inpatients under close supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of imipres 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| CYP2D6 inhibitors | Major | |
| Anticholinergics | Moderate | |
| CNS depressants | Moderate | |
| Sympathomimetics | Minor |
🚨 Major Interactions
- MAO inhibitors
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., benztropine, diphenhydramine)
- CNS depressants (e.g., alcohol, benzodiazepines)
🍷 Alcohol Interaction
Alcohol increases the sedative effects of imipramine and may worsen depression. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to imipramine or other tricyclic antidepressants","Concurrent use of MAO inhibitors","Acute recovery phase after myocardial infarction","Uncontrolled glaucoma","Urinary retention","Severe liver disease"]
⚠️ Warnings & Precautions
["May increase suicidal thoughts in children, adolescents, and young adults.","Do not stop abruptly; taper gradually to avoid withdrawal.","Use with caution in patients with seizures, hyperthyroidism, or cardiovascular disease.","May impair ability to drive or operate machinery.","Avoid alcohol and other CNS depressants."]
🤱 Lactation Safety
Imipramine is excreted in breast milk. Consult your doctor before breastfeeding; monitoring of infant for sedation and feeding difficulties is recommended.
💊 Overdose Management
Imipramine overdose is life-threatening. Symptoms include irregular heartbeat, severe hypotension, seizures, and coma. Seek emergency medical care immediately. Treatment is supportive and may include sodium bicarbonate for cardiac toxicity.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not stop suddenly as it may cause withdrawal symptoms. Avoid alcohol and other central nervous system depressants. Use caution when driving or operating machinery until you know how this medicine affects you. Inform your doctor about all other medications you are taking, especially MAO inhibitors, as dangerous interactions can occur. This medicine may increase suicidal thoughts in young adults; close monitoring is required. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to anticholinergic and cardiac effects. Start with low doses and monitor closely for confusion, falls, and arrhythmias.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor to discuss risks and benefits. Imipramine may be continued if necessary, but monitoring is required.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine. It may interact with anesthetic agents and affect blood pressure and heart rhythm.
🦷 Dental Procedures
Dry mouth from this medicine may increase risk of dental caries. Inform your dentist and maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise may help improve mood, but avoid strenuous activities if you experience dizziness or drowsiness. Stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and impair concentration. Avoid driving or operating heavy machinery until you know how it affects you. Discuss work accommodations if needed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or need to discontinue, your doctor will guide you through a gradual taper.
📅 Long-Term Use Effects
Long-term use may require periodic monitoring of blood counts, liver function, and ECG. Weight gain and dental problems due to dry mouth may occur. Regular follow-up is essential to adjust dosage and manage side effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be as effective as medication for mild to moderate depression.
Evidence: Well-establishedHas antidepressant effects and improves overall well-being.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. Consult your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. If traveling across time zones, adjust dosing schedule gradually under medical advice. Store in a cool, dry place away from direct sunlight. Check customs regulations for controlled substances before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It may take 2 to 4 weeks for full antidepressant effects. Some side effects may occur earlier.
A: No, stopping abruptly can cause withdrawal symptoms and relapse. Consult your doctor before stopping.
A: Consult your doctor. Imipramine may be used if benefits outweigh risks, but close monitoring is needed.
🤔 Common Patient Concerns
🔄 Substitutes for imipres 50mg tablet
View AllAlternative brands with exact same active ingredient:
-
pim 50mg tabletAan Pharma Pvt Ltd ₹14.06 21.1% CHEAPER
-
zemidep 50mg tabletLia Life Sciences Pvt Ltd ₹14.06 21.1% CHEAPER
-
min 50mg tabletHaryana Formulations Pvt Ltd ₹15.94 10.5% CHEAPER
-
antipres 50mg tabletPsycormedies ₹16.34 8.3% CHEAPER
-
dimip 50mg tabletD D Pharmaceuticals ₹17.81 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Imipramine is addictive.
Fact: Imipramine is not addictive, but it can cause withdrawal symptoms if stopped abruptly. It should be tapered gradually. - Myth: You can stop taking imipramine once you feel better.
Fact: You should continue taking it as prescribed to prevent relapse. Stopping suddenly can cause withdrawal and return of symptoms.
🔄 Alternative Options
Generic Alternatives
- Imipramine hydrochloride 50mg tablet
Brand Alternatives
- Tofranil
- Imipramine