idoxine powder - Cadexomer Iodine (1000mg) medicine

Idoxine Powder: Complete Guide To Uses, Side Effects, And Safety

No reviews yet
🏭 Franco-Indian Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate to well-established for chronic wounds.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, or throat, difficulty breathing, or widespread rash.
  • Signs of iodine toxicity: metallic taste, increased salivation, headache, or gastrointestinal upset.
  • Symptoms of thyroid dysfunction: rapid heartbeat, unexplained weight loss or gain, fatigue, or anxiety.
  • Severe skin irritation, blistering, or worsening of the wound.
  • No improvement in wound healing after 1-2 weeks of use.
  • Fever or chills, which may indicate a systemic infection.

If experiencing severe symptoms, call emergency services immediately.

What is idoxine powder used for?

This medicine is a topical antiseptic powder containing Cadexomer Iodine. It is used to treat chronic wounds, ulcers, and infected skin lesions by killing bacteria and absorbing wound fluid. Apply as directed by your doctor.

  • Generic Name: Cadexomer Iodine (1000mg)
  • Manufacturer: Franco-Indian Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 idoxine powder के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल एंटीसेप्टिक पाउडर है जिसमें कैडेक्सोमर आयोडीन सक्रिय तत्व है। इसका उपयोग पुराने घावों, अल्सर, और संक्रमित त्वचा के घावों के इलाज के लिए किया जाता है। यह घाव से तरल पदार्थ सोखता है और धीरे-धीरे आयोडीन छोड़ता है जो बैक्टीरिया, फंगस और वायरस को मारता है। यह घाव की बदबू कम करने और घाव भरने में मदद करता है। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, अस्थायी दाग, और त्वचा में लालिमा शामिल हैं। कभी-कभी खुजली या दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सूजन, या सांस लेने में कठिनाई हो सकती है। लंबे समय तक बड़े घावों पर उपयोग से थायरॉइड की समस्या हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को बताएं यदि आपको आयोडीन से एलर्जी है, थायरॉइड की समस्या है, या आप गर्भवती या स्तनपान करा रही हैं। इस दवा को केवल प्रभावित क्षेत्र पर ही लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क से बचें। बड़े घावों पर बिना डॉक्टर की सलाह के लंबे समय तक उपयोग न करें। बच्चों की पहुंच से दूर रखें। एक्सपायरी डेट के बाद उपयोग न करें। गंभीर जलन, सूजन या सांस लेने में कठिनाई होने पर तुरंत डॉक्टर से मिलें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 idoxine powder Uses & Benefits

[{"condition":"Chronic wounds (pressure ulcers, venous leg ulcers, diabetic foot ulcers)","description":"This medicine helps to clean the wound, reduce bacterial load, and control odour, promoting a healthy healing environment.","evidence":"Well-established"},{"condition":"Infected traumatic wounds","description":"It provides broad-spectrum antimicrobial action to prevent or treat infection in minor to moderate wounds.","evidence":"Well-established"},{"condition":"Fungal skin infections","description":"The iodine component is effective against various fungi, helping to resolve superficial fungal infections.","evidence":"Moderate"},{"condition":"Burn wounds (superficial)","description":"It can be used to prevent infection in superficial burns under medical supervision.","evidence":"Limited"}]

Off-label uses: [{"condition":"Infected eczema","description":"Sometimes used off-label to manage secondary bacterial infection in eczema lesions.","evidence":"Limited"},{"condition":"Onychomycosis (nail fungus)","description":"Rarely used off-label for fungal nail infections, but evidence is insufficient.","evidence":"Insufficient"}]

Primary treatment for: Chronic wounds and infected skin lesions

Also treats: Diabetic foot ulcers, Venous leg ulcers, Pressure ulcers, Infected traumatic wounds

📋 Drug Information

Generic Name(s)Cadexomer Iodine (1000mg)
Brand Nameidoxine powder
ManufacturerFranco-Indian Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C) in a dry place. Keep the container tightly closed. Protect from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always clean the wound thoroughly before applying this medicine to ensure maximum effectiveness.
2
Apply a thin, even layer of the powder to the wound; a thick layer is not necessary and may cause irritation.
3
Use a sterile applicator or wear gloves when applying to prevent contamination.
4
Monitor the wound for signs of improvement; if no improvement is seen within 1-2 weeks, consult your doctor.
5
Avoid using this medicine on large wounds or for prolonged periods without medical supervision to prevent iodine absorption.
6
Inform your doctor if you have a history of thyroid problems before using this medicine.
7
Keep the wound covered with an appropriate dressing as advised by your healthcare provider.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic wound or ulcer
This medicine is commonly prescribed for this.
Likely Use
✅
Infected skin lesion
This medicine helps to treat infection.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not used for headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption of iodine from this medicine is minimal when applied to intact skin or small wounds. However, significant absorption can occur when used on large wounds, burns, or mucous membranes, or with prolonged use. The extent of absorption depends on the wound size, duration of use, and the condition of the skin.
DistributionAbsorbed iodine is distributed throughout the body, primarily to the thyroid gland, but also to other tissues such as the salivary glands, gastric mucosa, and kidneys. Iodine does not cross the blood-brain barrier significantly but can cross the placenta and be excreted in breast milk.
Protein BindingNot established from the available information.
MetabolismIodine is not metabolized in the conventional sense. In the body, it is reduced to iodide, which is then utilized by the thyroid gland or excreted.
Half-LifeNot established from the available information.
ExcretionAbsorbed iodine is primarily excreted by the kidneys in the urine. Small amounts may also be excreted in faeces, sweat, and saliva.
BioavailabilityNot established from the available information.
Onset of ActionThe antimicrobial action of this medicine begins upon contact with the wound, as iodine is released from the cadexomer matrix. The onset is rapid, typically within minutes to hours.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe antimicrobial effect lasts as long as iodine is being released from the cadexomer beads, which depends on the amount of exudate and the frequency of application. Typically, the effect lasts for several hours, and the dressing is changed as directed by a healthcare professional.

How It Works

This medicine works through the combined action of cadexomer, a modified starch polymer, and iodine. When applied to a wound, the cadexomer beads absorb exudate and fluid, swelling to form a gel. As the beads absorb fluid, they slowly release iodine in a controlled manner. The released iodine penetrates microbial cell walls and disrupts protein synthesis, nucleic acid function, and cell membrane integrity, leading to the death of bacteria, fungi, and viruses. This sustained release provides a continuous antimicrobial effect while minimizing systemic iodine absorption. The absorption of exudate also helps to clean the wound bed and reduce odour.

Mechanism Steps

1
Application and fluid absorption: The powder is applied to the wound, where the cadexomer beads absorb wound exudate and fluid.
2
Gel formation: As the beads absorb fluid, they swell and form a gel, creating a moist environment that supports healing.
3
Controlled iodine release: The swelling beads gradually release iodine in a sustained manner, providing continuous antimicrobial activity.
4
Microbial killing: The released iodine penetrates microbial cells, disrupting essential cellular processes and leading to cell death.
5
Wound debridement and odour control: The absorption of exudate and debris helps to clean the wound and reduce odour, promoting a healthy healing environment.

💡 How to Take idoxine powder

Strength: Powder containing 1000 mg Cadexomer Iodine per gram.

1Wash your hands thoroughly before and after applying this medicine.
2Clean the wound gently with sterile saline or as directed by your healthcare provider.
3Pat the area dry with a sterile gauze.
4Apply a thin layer of the powder to the affected area using a clean applicator or gloves.
5Cover the wound with a suitable dressing if advised by your doctor.
6Do not rub the powder into the skin.
7Dispose of used applicators and gloves properly.
8Wash your hands again after application.

Dosage Information

Adult DosageThe usual adult dose of this medicine is to apply a thin layer of powder to the affected area once or twice daily, or as directed by your healthcare provider. The exact frequency and duration depend on the type, size, and severity of the wound, as well as your overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of iodine, especially if they have thyroid or kidney problems. Use with caution and under medical supervision. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. However, use with caution in patients with severe renal impairment due to potential systemic absorption of iodine. Consult your doctor.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and consult your doctor.
Maximum Daily DoseNot established from the available information. Use as directed by your healthcare provider.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of idoxine powder

✅ Common Side Effects

Mild burning or stinging at application site (Common (5-10%))
This usually resolves on its own. If it persists or worsens, consult your doctor.
Temporary skin staining (Common (5-10%))
Staining is temporary and will fade. Avoid applying to clothing or fabrics as it may stain.
Local irritation or redness (Common (5-10%))
If irritation is severe or persists, stop use and consult your doctor.
Itching (Uncommon (1-5%))
If itching is bothersome, consult your doctor. Avoid scratching the treated area.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, or throat, difficulty breathing, or a widespread rash.
Thyroid dysfunction (hyperthyroidism or hypothyroidism) (Rare (<0.1%))
Prolonged use on large wounds may affect thyroid function. Consult your doctor if you experience symptoms such as rapid heartbeat, weight changes, or fatigue.
Iodine toxicity (Rare (<0.1%))
Symptoms include metallic taste, increased salivation, headache, and gastrointestinal upset. Seek medical attention if these occur.

⚠️ Rare Side Effects

Contact dermatitis
Discontinue use and consult a doctor if you develop a rash, blistering, or severe redness.
Systemic iodine absorption leading to metabolic acidosis
Seek immediate medical attention if you experience confusion, rapid breathing, or extreme fatigue.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Lithium Major
Antithyroid agents Major
Hydrogen peroxide Moderate
Silver sulfadiazine Moderate
Topical corticosteroids Minor

🚨 Major Interactions

  • Lithium
  • Antithyroid agents (e.g., methimazole, propylthiouracil)

⚡ Moderate Interactions

  • Hydrogen peroxide
  • Silver sulfadiazine

🍷 Alcohol Interaction

No known interaction between this medicine and alcohol. However, alcohol may impair wound healing and should be avoided while recovering from a wound.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to iodine or any component of the medicine","Hyperthyroidism or other thyroid disorders","Use on large open wounds without medical supervision","Use in patients with a history of thyroid disease","Use on mucous membranes or eyes"]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes, mouth, and other mucous membranes.","Do not use on large wounds or for prolonged periods without medical advice.","Use with caution in patients with renal impairment.","Use with caution in pregnant and breastfeeding women.","Keep out of reach of children.","Do not use if the packaging is damaged or expired.","Discontinue use if severe irritation or allergic reaction occurs."]

🤱 Lactation Safety

Iodine is excreted in breast milk. Use with caution during breastfeeding, especially on large wounds or for prolonged periods. Consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of iodine overdose may include abdominal pain, nausea, vomiting, metallic taste, and in severe cases, thyroid dysfunction. Treatment is supportive and symptomatic. Contact a poison control center or emergency department if ingestion is suspected.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are allergic to iodine, have thyroid problems, or are pregnant or breastfeeding. Apply this medicine only to the affected area as directed by your healthcare provider. Do not use it on large wounds or for prolonged periods without medical supervision. Avoid contact with eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not cover the wound with airtight dressings unless instructed. Keep this medicine out of reach of children. Do not use this medicine after the expiry date. If you experience severe irritation, swelling, or difficulty breathing, stop use and seek immediate medical help. Always wash your hands before and after applying this medicine. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to iodine absorption and its effects on thyroid function. Use with caution and monitor thyroid function if used on large wounds or for prolonged periods.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Use with caution, especially on large wounds or for prolonged periods.

🏥 Post-Surgery Considerations

This medicine may be used on surgical wounds under medical supervision. Follow your surgeon's instructions for wound care. Do not apply to surgical incisions without approval.

🦷 Dental Procedures

This medicine is for topical skin use only and is not intended for dental procedures. If you have a dental procedure, inform your dentist about any medications you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the wound clean and dry to promote healing.
🥗
Eat a balanced diet rich in protein and vitamins to support wound healing.
😴
Avoid smoking, as it impairs blood flow and delays healing.
💧
Manage underlying conditions like diabetes and hypertension.
🧘
Elevate the affected limb if advised to reduce swelling.
🌞
Avoid putting pressure on the wound area.

🏋️ Exercise Considerations

Avoid strenuous exercise that may put pressure on the wound or cause it to reopen. Gentle movement and walking may be beneficial for circulation, but consult your doctor before starting any exercise routine.

🥗 Diet Recommendations

Include protein-rich foods like eggs, fish, and legumes.
Eat fruits and vegetables rich in vitamin C and zinc.
Stay well hydrated.
Limit sugary and processed foods.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or discomfort, avoid these activities until you feel better. You can continue your normal daily activities as tolerated, but avoid activities that may contaminate or injure the wound.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if you experience severe irritation, allergic reaction, or if the wound shows no improvement after 1-2 weeks. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Prolonged use of this medicine on large wounds may lead to systemic absorption of iodine, which can affect thyroid function. Regular monitoring of thyroid function is advised if used extensively. Other long-term effects are rare. Always follow your doctor's instructions regarding duration of use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Povidone-iodine solution

Another topical antiseptic that can be used for wound cleaning.

Evidence: Well-established
Silver sulfadiazine cream

Used for burn wounds and infected skin lesions.

Evidence: Well-established
Honey-based dressings

Natural antimicrobial dressings that can promote wound healing.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction between this medicine and vaccines. However, if you have a wound infection, consult your doctor about the timing of vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep the container tightly closed

❌ DON'T

Do not use if the powder is discoloured or clumped

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from direct sunlight and moisture. If you are traveling across time zones, continue your regular application schedule as directed by your doctor. Do not leave the medicine in a hot car or checked luggage. If you have a wound that requires dressing changes, pack enough supplies for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man with a diabetic foot ulcer
He was prescribed this medicine for a non-healing diabetic foot ulcer. After using it as directed for three weeks, the wound showed significant reduction in size and odour. He also maintained good blood sugar control and kept his foot clean and dry.
💡 Lesson: Consistent application and proper wound care are key to healing. Managing underlying conditions like diabetes is equally important.
👤 A 45-year-old woman with a venous leg ulcer
She had a chronic leg ulcer that had not healed for months. Her doctor recommended this medicine along with compression therapy. Within four weeks, the ulcer began to granulate and eventually healed. She experienced mild stinging initially, which subsided with continued use.
💡 Lesson: Combining this medicine with compression therapy can enhance healing of venous ulcers. Mild side effects often diminish over time.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working upon contact with the wound. You may notice improvement in wound appearance and odour within a few days. Complete healing may take weeks depending on the wound type and your overall health.

Q: Can I use this medicine on burns?

A: It can be used on superficial burns under medical supervision. Do not use on deep or large burns without consulting a doctor.

Q: Is it safe for diabetics?

A: Yes, it is commonly used for diabetic foot ulcers. However, you must keep your blood sugar under control and follow your doctor's advice.

Q: Can I use it during pregnancy?

A: Use with caution during pregnancy, especially on large wounds or for prolonged periods. Consult your doctor before use.

Q: What should I do if I miss a dose?

A: Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • Will it stain my clothes?
  • Can I use it on my child?
  • How often should I change the dressing?
  • Can I take a bath with this medicine on?
  • What if I accidentally swallow it?

🔄 Substitutes for idoxine powder

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Idoxine powder can be used on any wound without medical advice.
    Fact: It should only be used on wounds as directed by a healthcare professional, especially for large or deep wounds.
  • Myth: Idoxine powder is safe for people with thyroid problems.
    Fact: People with thyroid disorders should avoid this medicine unless specifically advised by their doctor.
  • Myth: Idoxine powder works instantly.
    Fact: It provides sustained antimicrobial action, but wound healing takes time. Improvement may be seen over days to weeks.

🔄 Alternative Options

Generic Alternatives

  • Cadexomer Iodine Powder

Brand Alternatives

  • Idoxine Powder

📊 Comparison with Similar Medicines

[{"medicine":"Cadexomer Iodine Powder","active_ingredient":"Cadexomer Iodine","route":"Topical","main_use":"Chronic wounds","key_difference":"Sustained release of iodine, absorbs exudate"},{"medicine":"Povidone-Iodine Powder","active_ingredient":"Povidone-Iodine","route":"Topical","main_use":"Antiseptic for minor wounds","key_difference":"Immediate release, no exudate absorption"},{"medicine":"Silver Sulfadiazine Cream","active_ingredient":"Silver Sulfadiazine","route":"Topical","main_use":"Burn wounds","key_difference":"Silver-based antimicrobial, different spectrum"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory