idcold tablet - Caffeine (16mg) + Chlorpheniramine Maleate (2mg) medicine

Fraryl Tablet: Complete Medicine Guide

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🏭 Paridhi Remedies 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, tongue, or throat
  • Irregular or fast heartbeat
  • Severe dizziness or fainting
  • Hallucinations or confusion
  • Inability to urinate
  • Yellowing of skin or eyes
  • Severe abdominal pain

If experiencing severe symptoms, call emergency services immediately.

What is idcold tablet used for?

This medicine is a combination of caffeine and chlorpheniramine maleate used to relieve allergy and cold symptoms such as sneezing, runny nose, and itchy eyes. It works by blocking histamine and reducing drowsiness.

  • Generic Name: Caffeine (16mg) + Chlorpheniramine Maleate (2mg)
  • Manufacturer: Paridhi Remedies
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 idcold tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी के लक्षणों जैसे छींक, नाक बहना, आंखों में खुजली और पानी आना, और नाक बंद होने में राहत देती है। यह कैफीन और क्लोरफेनिरामाइन मेलिएट का संयोजन है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, जी मिचलाना और बेचैनी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, अनियमित दिल की धड़कन, भ्रम या पेशाब रोकने में कठिनाई हो सकती है।

सुरक्षा सलाह: दवा की खुराक से अधिक न लें। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, वाहन न चलाएं। शराब से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 idcold tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides temporary relief of cold symptoms such as sneezing, runny nose, and watery eyes.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps reduce itching and hives due to allergic reactions.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Insomnia due to mild sedation","description":"Sometimes used off-label for its sedative effects, but caffeine may counteract this.","evidence":"Limited"},{"condition":"Motion sickness","description":"Occasionally used for motion sickness due to antihistamine effects.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Urticaria

📋 Drug Information

Generic Name(s)Caffeine (16mg) + Chlorpheniramine Maleate (2mg)
Brand Nameidcold tablet
ManufacturerParidhi Remedies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk if it upsets your stomach.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine as it can increase drowsiness.
4
Limit caffeine intake from other sources to avoid nervousness and insomnia.
5
Consult your doctor if symptoms persist beyond 7 days or worsen.
6
Do not use this medicine for longer than directed without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing
This medicine is commonly prescribed for this.
Likely Use
✅
Runny nose
This medicine helps reduce nasal secretions.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Itchy eyes
This medicine relieves allergic eye symptoms.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine is well absorbed from the gastrointestinal tract, with peak plasma levels occurring within 2 to 3 hours. Caffeine is rapidly absorbed, reaching peak plasma concentrations within 30 to 60 minutes.
DistributionChlorpheniramine is widely distributed in body tissues and crosses the blood-brain barrier. Caffeine also distributes throughout body fluids and crosses the placenta and blood-brain barrier.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Caffeine is about 25% bound to plasma proteins.
MetabolismChlorpheniramine is metabolized in the liver primarily by CYP2D6 and CYP3A4. Caffeine is metabolized in the liver by CYP1A2 to paraxanthine, theobromine, and theophylline.
Half-LifeChlorpheniramine half-life is approximately 12 to 43 hours. Caffeine half-life is about 3 to 7 hours.
ExcretionChlorpheniramine and its metabolites are excreted mainly in urine. Caffeine metabolites are excreted in urine.
BioavailabilityChlorpheniramine oral bioavailability is about 25 to 50%. Caffeine oral bioavailability is nearly 100%.
Onset of ActionChlorpheniramine effects begin within 30 to 60 minutes. Caffeine effects begin within 15 to 30 minutes.
Peak Plasma TimeChlorpheniramine peak plasma time is 2 to 3 hours. Caffeine peak plasma time is 30 to 60 minutes.
Duration of ActionChlorpheniramine effects last 4 to 6 hours. Caffeine effects last 3 to 5 hours.

How It Works

Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing allergic responses. Caffeine is a central nervous system stimulant that antagonizes adenosine receptors, increasing alertness and counteracting sedation.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine binds to H1 receptors on smooth muscle and blood vessels, preventing histamine from causing vasodilation, increased permeability, and itching.
2
Anticholinergic action: Chlorpheniramine also blocks muscarinic acetylcholine receptors, reducing secretions such as runny nose and tearing.
3
Adenosine receptor antagonism: Caffeine blocks adenosine receptors in the brain, leading to increased neuronal firing and release of neurotransmitters like dopamine and norepinephrine, promoting alertness.
4
Counteraction of sedation: The stimulant effect of caffeine helps offset the drowsiness caused by chlorpheniramine, improving daytime functioning.

💡 How to Take idcold tablet

Strength: Tablet: Caffeine 16 mg + Chlorpheniramine Maleate 2 mg

1Take this medicine orally with a glass of water.
2It can be taken with or without food.
3If stomach upset occurs, take with food or milk.
4Do not crush, chew, or break the tablet unless instructed.
5Follow the prescribed dose and frequency exactly.

Dosage Information

Adult DosageThe usual adult dose is one tablet every 4 to 6 hours as needed, not to exceed 6 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the anticholinergic and sedative effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor.
Maximum Daily Dose6 tablets in 24 hours.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Caffeine-containing beverages
Limit
May increase stimulant side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of idcold tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-15%))
Sip water, chew sugarless gum, or use saliva substitutes. Consult dentist if persistent.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid alcohol.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.
Nervousness (Common (5-10%))
Limit caffeine intake from other sources. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help if you experience rash, itching, swelling of face, lips, tongue, or throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Contact a doctor immediately if you feel palpitations, chest pain, or shortness of breath.
Hallucinations or confusion (Rare (<0.1%))
Stop the medicine and seek medical attention if you experience hallucinations, confusion, or unusual thoughts.
Urinary retention (Rare (<0.1%))
Seek medical help if you are unable to urinate or have difficulty passing urine.

⚠️ Rare Side Effects

Blood dyscrasias (e.g., agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor immediately.
Hepatotoxicity
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Alcohol Major
Anticholinergics Major
CYP2D6 inhibitors Moderate
CYP3A4 inhibitors Moderate
Caffeine Moderate
Antacids Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Alcohol and other CNS depressants
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)

⚡ Moderate Interactions

  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
  • Caffeine-containing products

🍷 Alcohol Interaction

Alcohol increases the sedative effects of chlorpheniramine and may enhance CNS depression. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, caffeine, or any component of the formulation","Narrow-angle glaucoma","Urinary retention","Severe hypertension","Coronary artery disease","Use with MAOIs"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, prostate enlargement, or cardiovascular disease.","May cause dry mouth, constipation, and urinary retention.","Do not exceed recommended dose.","Consult a doctor if symptoms persist beyond 7 days."]

🤱 Lactation Safety

Chlorpheniramine and caffeine are excreted in breast milk. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, tachycardia, hallucinations, seizures, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Avoid alcohol and other central nervous system depressants. Consult a doctor before use if you are pregnant, breastfeeding, or have glaucoma, prostate enlargement, or heart disease. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the anticholinergic and sedative effects of chlorpheniramine. Use with caution and consider lower doses. Monitor for confusion, urinary retention, and falls.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy or are pregnant. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with anesthetics and other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Avoid known allergens such as dust, pollen, and pet dander.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Wash bedding frequently in hot water.
💧
Stay hydrated to reduce dry mouth.
🧘
Get adequate rest to support immune function.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Include vitamin C-rich foods to support immune health.
Avoid excessive caffeine from coffee, tea, and energy drinks.
Stay well hydrated.
Eat a balanced diet with plenty of fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is best to avoid these activities until you know how the medicine affects you. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if symptoms persist beyond 7 days, worsen, or if you experience severe side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, dependence, and increased risk of side effects such as cognitive impairment and anticholinergic effects. Regular review by a doctor is recommended if used for more than 7 days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Reducing exposure to allergens can help prevent symptoms.

Evidence: Well-established
Nasal saline irrigation

Can help relieve nasal congestion and rinse allergens.

Evidence: Moderate
Second-generation antihistamines

Less sedating alternatives for allergy relief.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. Consult your doctor regarding vaccination timing while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She started taking this medicine for sneezing and runny nose. She noticed relief within an hour but felt drowsy. She adjusted her dose to bedtime and found it effective without daytime sedation.
💡 Lesson: Taking this medicine at bedtime can help manage drowsiness while still relieving allergy symptoms.
👤 A 50-year-old man with common cold
He took this medicine for a cold and experienced dry mouth and mild dizziness. He stayed hydrated and avoided driving. Symptoms improved in 3 days.
💡 Lesson: Staying hydrated and avoiding driving can help manage side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking it.

Q: Can I take it at night?

A: Yes, but it may cause drowsiness. Many people take it at bedtime to help with sleep while relieving symptoms.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician before giving this medicine to children.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for idcold tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to drive after taking this medicine.
    Fact: This medicine can cause drowsiness; avoid driving until you know how it affects you.

🔄 Alternative Options

Generic Alternatives

  • Caffeine + Chlorpheniramine Maleate Tablet

Brand Alternatives

  • Fraryl Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Chlorpheniramine alone","difference":"Lacks caffeine; may cause more drowsiness."},{"medicine":"Caffeine alone","difference":"Lacks antihistamine; does not relieve allergy symptoms."}]

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