ictrol 150mg tablet - Lacosamide (150mg) medicine

Emsilac 150mg Tablet: Complete Medicine Guide

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🏭 Intas Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Thoughts of self-harm or suicide
  • Irregular or slow heartbeat
  • Severe allergic reaction with swelling of face, lips, or throat
  • Sudden rash, blisters, or peeling skin
  • Yellowing of skin or eyes
  • Severe dizziness or fainting
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is ictrol 150mg tablet used for?

This medicine is an antiepileptic drug used to treat partial-onset seizures and primary generalized tonic-clonic seizures in adults and children 4 years and older. It works by stabilizing neuronal membranes and reducing abnormal electrical activity in the brain.

  • Generic Name: Lacosamide (150mg)
  • Manufacturer: Intas Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ictrol 150mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लैकोसामाइड नामक एंटीपाइलेप्टिक दवा है, जिसका उपयोग आंशिक-शुरुआत दौरे (फोकल दौरे) और प्राथमिक सामान्यीकृत टॉनिक-क्लोनिक दौरे के इलाज के लिए किया जाता है। यह मस्तिष्क में असामान्य विद्युत गतिविधि को कम करके दौरे को नियंत्रित करने में मदद करती है। यह दवा 4 वर्ष और उससे अधिक उम्र के बच्चों और वयस्कों में उपयोग की जा सकती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, मतली, उल्टी, धुंधली दृष्टि, थकान और संतुलन की समस्या शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन आत्मघाती विचार, गंभीर एलर्जी प्रतिक्रिया, और हृदय ताल में बदलाव हो सकते हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे दौरे बढ़ सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। शराब का सेवन न करें। अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 ictrol 150mg tablet Uses & Benefits

[{"condition":"Partial-onset seizures (focal seizures)","description":"This medicine is indicated as monotherapy or adjunctive therapy for the treatment of partial-onset seizures in adults and children aged 4 years and older.","evidence":"Well-established"},{"condition":"Primary generalized tonic-clonic seizures","description":"This medicine is indicated as adjunctive therapy for primary generalized tonic-clonic seizures in adults and children aged 4 years and older.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes prescribed off-label for neuropathic pain, though evidence is limited.","evidence":"Limited"},{"condition":"Status epilepticus","description":"May be used off-label in the management of status epilepticus, but not a first-line agent.","evidence":"Limited"}]

Primary treatment for: Epilepsy

Also treats: Partial-onset seizures, Primary generalized tonic-clonic seizures

📋 Drug Information

Generic Name(s)Lacosamide (150mg)
Brand Nameictrol 150mg tablet
ManufacturerIntas Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSodium channel modulators (AED)
Route of AdministrationOral
StorageStore at room temperature between 20°C and 25°C (68°F to 77°F). Keep in a dry place away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same times each day to maintain steady blood levels.
2
Do not stop this medicine suddenly without consulting your doctor, as it can trigger seizures.
3
Avoid driving or operating heavy machinery until you know how this medicine affects you.
4
Inform your doctor if you have a history of heart problems, as this medicine can affect heart rhythm.
5
Report any changes in mood, especially thoughts of self-harm, to your doctor immediately.
6
Keep all follow-up appointments and get regular blood tests as advised.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Partial-onset seizures
This medicine is commonly prescribed for this.
Likely Use
✅
Primary generalized tonic-clonic seizures
This medicine is indicated for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and completely absorbed after oral administration. Food does not affect the rate or extent of absorption.
DistributionThis medicine distributes into body tissues, with a volume of distribution of approximately 0.6 L/kg.
Protein BindingLess than 15% of this medicine is bound to plasma proteins.
MetabolismThis medicine is metabolized in the liver, primarily by CYP2C19, CYP3A4, and CYP2C9 enzymes.
Half-LifeThe elimination half-life of this medicine is approximately 13 hours.
ExcretionThis medicine is excreted primarily in the urine (approximately 95%), with about 40% as unchanged drug and the rest as metabolites.
BioavailabilityThe oral bioavailability of this medicine is approximately 100%.
Onset of ActionThe onset of anticonvulsant action is not immediate; it may take several days to weeks to achieve full therapeutic effect.
Peak Plasma TimePeak plasma concentrations of this medicine are reached 1 to 4 hours after oral administration.
Duration of ActionThe duration of action of this medicine is approximately 12 hours, corresponding to its twice-daily dosing schedule.

How It Works

This medicine selectively enhances the slow inactivation of voltage-gated sodium channels, leading to stabilization of neuronal membranes and inhibition of repetitive neuronal firing. This action reduces the spread of seizure activity in the brain.

Mechanism Steps

1
Binding to sodium channels: This medicine binds to voltage-gated sodium channels in their slow-inactivated state.
2
Enhancement of slow inactivation: It stabilizes the slow-inactivated state, preventing the channels from returning to the resting state quickly.
3
Reduced neuronal firing: This reduces the frequency of repetitive neuronal firing, which helps control seizures.

💡 How to Take ictrol 150mg tablet

Strength: 150 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You may take it with or without food.
4Take it at the same times each day to maintain consistent blood levels.
5Do not crush, chew, or break the tablet unless instructed by your doctor.

Dosage Information

Adult DosageThe recommended initial dose of this medicine is 50 mg twice daily, which may be increased to 100 mg twice daily after one week, and further to 200 mg twice daily if needed. The maximum recommended dose is 400 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Start with a lower dose and titrate slowly.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance less than 30 mL/min), the maximum dose should be reduced by 25%. In patients with end-stage renal disease, this medicine should be used with caution.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, no dose adjustment is needed. In severe hepatic impairment, use with caution and consider dose reduction.
Maximum Daily Dose400 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
No restriction
Food does not affect the absorption of this medicine.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ictrol 150mg tablet

✅ Common Side Effects

Dizziness (Common (10-30%))
Avoid driving or operating machinery until you know how this medicine affects you. If dizziness persists, consult your doctor.
Headache (Common (10-20%))
Usually resolves on its own. If severe or persistent, consult your doctor.
Nausea (Common (5-15%))
Take with food to reduce nausea. If it continues, talk to your doctor.
Vomiting (Common (5-10%))
Stay hydrated. If vomiting is severe or persistent, contact your doctor.
Double vision (Common (5-15%))
Avoid driving if affected. Report to your doctor if it persists.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.

🚨 Serious Side Effects

Suicidal thoughts or behavior (Uncommon (<1%))
Seek immediate medical help if you experience any thoughts of self-harm.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical attention if you have swelling of the face, lips, tongue, or throat, or difficulty breathing.
Heart rhythm changes (PR interval prolongation) (Uncommon (<1%))
Report any fainting, dizziness, or irregular heartbeat to your doctor immediately.
Stevens-Johnson syndrome (Rare (<0.1%))
Seek immediate medical attention if you develop a rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Agranulocytosis
Report any signs of infection such as fever, sore throat, or mouth ulcers to your doctor promptly.
Hepatitis
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Carbamazepine Major
Lamotrigine Major
Pregabalin Major
Ketoconazole Moderate
Ritonavir Moderate
Omeprazole Moderate
Diazepam Moderate
Morphine Moderate
Oral contraceptives Minor

🚨 Major Interactions

  • Drugs that prolong PR interval (e.g., carbamazepine, lamotrigine, pregabalin)
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • CYP2C19 inhibitors (e.g., omeprazole)
  • CNS depressants (e.g., benzodiazepines, opioids)

🍷 Alcohol Interaction

Alcohol may increase the central nervous system depressant effects of this medicine, leading to increased drowsiness, dizziness, and impaired coordination. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to lacosamide or any component of the formulation","Second- or third-degree heart block without a pacemaker"]

⚠️ Warnings & Precautions

["Suicidal thoughts and behavior: Monitor patients for depression, suicidal thoughts, or unusual changes in mood or behavior.","Heart rhythm abnormalities: This medicine may cause PR interval prolongation. Use with caution in patients with cardiac conduction issues.","Dizziness and ataxia: May impair ability to drive or operate machinery.","Withdrawal of antiepileptic drugs: Do not stop abruptly to avoid precipitating seizures.","Multi-organ hypersensitivity: Rarely, this medicine can cause a serious multi-organ hypersensitivity reaction."]

🤱 Lactation Safety

This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

💊 Overdose Management

There is no specific antidote for overdose with this medicine. In case of overdose, immediate medical attention is required. Treatment should be symptomatic and supportive. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice, as stopping suddenly can cause seizures. Avoid driving or operating heavy machinery until you know how this medicine affects you, because it can cause dizziness and drowsiness. Inform your doctor if you have a history of heart problems, kidney or liver disease, or depression. Do not drink alcohol while taking this medicine, as it can increase drowsiness and dizziness. Keep all follow-up appointments and report any new or worsening symptoms promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and balance problems. Dose adjustment based on renal function is often necessary. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before conception. This medicine should be used during pregnancy only if clearly needed. Effective contraception is recommended for women of childbearing potential.

🏥 Post-Surgery Considerations

After surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rhythm. Your dose may need adjustment during the perioperative period.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain anesthetics or sedatives. Your dentist may need to take precautions.

💚 Lifestyle Tips for Better Results

🏃
Get adequate sleep, as sleep deprivation can trigger seizures.
🥗
Manage stress through relaxation techniques like yoga or meditation.
😴
Avoid alcohol and recreational drugs.
💧
Maintain a regular meal schedule.
🧘
Wear a medical alert bracelet indicating you have epilepsy.
🌞
Keep a seizure diary to track frequency and triggers.

🏋️ Exercise Considerations

Exercise is generally safe, but avoid activities that could be dangerous if you experience dizziness or seizures, such as swimming alone or high-altitude climbing. Consult your doctor before starting a new exercise regimen.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Stay well hydrated.
Limit caffeine and alcohol intake.
Consider a ketogenic diet only under medical supervision.

💼 Impact on Daily Work & Life

This medicine may cause dizziness and drowsiness, which can affect your ability to drive or operate machinery. It is important to assess your individual response before engaging in such activities. Most people can continue their normal work with appropriate precautions.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or your seizures are well-controlled, your doctor may consider gradually tapering the dose. Abrupt discontinuation can lead to withdrawal seizures.

📅 Long-Term Use Effects

Long-term use of this medicine may require regular monitoring of kidney and liver function, as well as heart rhythm. Some patients may experience tolerance or reduced efficacy over time. It is important to have periodic evaluations to ensure the medicine remains safe and effective.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ketogenic diet

A high-fat, low-carbohydrate diet that may help reduce seizures in some patients, especially children.

Evidence: Well-established for certain types of epilepsy
Vagus nerve stimulation

A device implanted under the skin that sends electrical impulses to the vagus nerve to reduce seizures.

Evidence: Well-established for refractory epilepsy
Epilepsy surgery

Surgical removal of the brain area causing seizures, considered for some patients with focal seizures.

Evidence: Well-established for selected patients

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine, especially live vaccines, as your immune response may vary.

📦 Storage Guide

✅ DO

Store at room temperature (20-25°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting dosing times. Check local customs regulations for controlled substances.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with partial-onset seizures
She had been struggling with frequent seizures despite taking other medications. Her doctor prescribed this medicine as add-on therapy. After a few weeks, her seizure frequency reduced significantly. She experienced mild dizziness initially, which improved over time. She emphasizes the importance of taking the medicine regularly and avoiding alcohol.
💡 Lesson: Consistent adherence to this medicine can lead to better seizure control, and side effects often diminish with time.
👤 A 50-year-old man with primary generalized tonic-clonic seizures
He started this medicine after his previous medication caused intolerable side effects. He found this medicine effective in controlling his seizures. He had to adjust the dose gradually under his doctor's supervision. He advises others to never skip doses and to communicate openly with their doctor about any side effects.
💡 Lesson: Gradual dose titration and regular communication with the healthcare provider are key to successful treatment with this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within a few hours, but full therapeutic effect may take several weeks. Your doctor will adjust the dose gradually.

Q: Can I stop taking this medicine if I feel better?

A: No, you should never stop this medicine without consulting your doctor. Stopping suddenly can cause seizures to return.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol and activities requiring alertness until you know how this medicine affects you. Also, avoid missing doses.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ictrol 150mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure epilepsy permanently.
    Fact: This medicine helps control seizures but does not cure epilepsy. It must be taken regularly as prescribed.
  • Myth: You can stop taking this medicine once seizures are controlled.
    Fact: Stopping this medicine suddenly can cause seizures to return. Always consult your doctor before making any changes.

🔄 Alternative Options

Generic Alternatives

  • Lacosamide

Brand Alternatives

  • Emsilac 150mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Emsilac 150mg Tablet","class":"Antiepileptic","primary_use":"Partial-onset seizures","route":"Oral"},{"medicine":"Carbamazepine","class":"Antiepileptic","primary_use":"Partial-onset seizures","route":"Oral"},{"medicine":"Lamotrigine","class":"Antiepileptic","primary_use":"Partial-onset seizures","route":"Oral"}]

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