Ibuprofen + Paracetamol Oral Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is ibupol oral suspension used for?
This medicine is a combination of ibuprofen and paracetamol used for relief of mild to moderate pain and fever. It works by reducing inflammation and acting on the brain to relieve pain and fever. Take it with food to avoid stomach upset and do not exceed the recommended dose.
- Generic Name: Ibuprofen (100mg/5ml) + Paracetamol (125mg/5ml)
- Manufacturer: Dwarkesh Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ibupol oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा इबुप्रोफेन और पैरासिटामोल का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मांसपेशियों में दर्द, मासिक धर्म में ऐंठन, और सर्दी-जुकाम से जुड़े बुखार में राहत देती है। यह सूजन को भी कम करती है, इसलिए गठिया जैसी स्थितियों में भी उपयोगी है।
साइड इफेक्ट्स: आम दुष्प्रभावों में पेट दर्द, जलन, मतली, उल्टी और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या और एलर्जी प्रतिक्रियाएं हो सकती हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खाली पेट न लें, भोजन या दूध के साथ लें। शराब का सेवन न करें। यदि आपको पेट अल्सर, गुर्दे या लीवर की बीमारी, या हृदय की समस्या है, तो डॉक्टर को बताएं। बिना सलाह के 3 दिन से अधिक बुखार या 10 दिन से अधिक दर्द के लिए न लें।
💊 ibupol oral suspension Uses & Benefits
[{"condition":"Mild to moderate pain","description":"Relieves pain such as headache, toothache, muscle ache, and menstrual cramps.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever associated with colds, flu, or other infections.","evidence":"Well-established"},{"condition":"Inflammatory conditions","description":"Reduces pain and inflammation in conditions like arthritis, bursitis, and tendonitis.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used to relieve migraine pain, though not a first-line treatment.","evidence":"Limited"},{"condition":"Post-operative pain","description":"May be used for short-term pain relief after surgery, but only under medical supervision.","evidence":"Limited"}]
Primary treatment for: Pain and fever
Also treats: Headache, Toothache, Muscle ache, Menstrual cramps, Arthritis, Cold and flu symptoms
📋 Drug Information
| Generic Name(s) | Ibuprofen (100mg/5ml) + Paracetamol (125mg/5ml) |
| Brand Name | ibupol oral suspension |
| Manufacturer | Dwarkesh Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the bottle tightly closed. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Ibuprofen works by inhibiting the cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins, substances that cause pain, inflammation, and fever. By blocking COX, ibuprofen reduces these symptoms. Paracetamol, on the other hand, acts primarily in the central nervous system to relieve pain and reduce fever, though its exact mechanism is not fully understood. It may also inhibit prostaglandin synthesis in the brain. Together, they provide synergistic pain relief and fever reduction.
Mechanism Steps
💡 How to Take ibupol oral suspension
Strength: Each 5 ml of oral suspension contains ibuprofen 100 mg and paracetamol 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 5-10 ml of the suspension every 4-6 hours as needed for pain or fever. Do not exceed 40 ml in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on the child's age and weight. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction may be necessary. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be necessary. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | For adults, the maximum daily dose is 40 ml of the suspension (providing 800 mg ibuprofen and 1000 mg paracetamol). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ibupol oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| ACE inhibitors | Major | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| Methotrexate | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Corticosteroids
- ACE inhibitors and ARBs
⚡ Moderate Interactions
- Diuretics
- Lithium
- Methotrexate
- SSRIs
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver damage, especially with paracetamol. It can also worsen the side effects of ibuprofen.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ibuprofen, paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic reaction after taking aspirin or other NSAIDs.","Active or history of recurrent peptic ulcer or gastrointestinal bleeding.","Severe heart failure, severe kidney impairment, or severe liver impairment.","Third trimester of pregnancy.","Children under 12 years of age (unless directed by a doctor)."]
⚠️ Warnings & Precautions
["Take with food or milk to reduce stomach upset.","Do not exceed the recommended dose or duration of treatment.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of side effects.","Consult your doctor if you have a history of stomach ulcers, kidney disease, liver disease, or heart problems.","Do not use for more than 3 days for fever or 10 days for pain without medical advice.","Keep out of reach of children."]
🤱 Lactation Safety
Ibuprofen and paracetamol are excreted in breast milk in small amounts. They are generally considered compatible with breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose can cause severe liver damage, especially from paracetamol, and gastrointestinal bleeding, kidney failure, and other complications from ibuprofen. If you suspect an overdose, seek emergency medical attention immediately. Treatment may include activated charcoal, gastric lavage, and administration of acetylcysteine for paracetamol toxicity. Supportive care and monitoring of vital organs are essential.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine, as it can increase the risk of stomach bleeding. If you have a history of stomach ulcers, kidney disease, liver disease, or heart problems, inform your doctor before taking this medicine. Do not use this medicine for more than 3 days for fever or 10 days for pain without consulting a doctor. Keep out of reach of children. Store at room temperature, away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like ibuprofen may affect ovulation and are generally avoided in the third trimester. Paracetamol is considered safer but should be used as directed.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your surgeon. It may increase the risk of bleeding and interfere with healing. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding during and after the procedure. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can continue light to moderate exercise as tolerated. However, if you experience dizziness or fatigue, avoid strenuous activities. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue your daily activities, but take precautions if you feel unwell.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve after 3 days for fever or 10 days for pain, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and cardiovascular events. Regular monitoring of kidney and liver function is recommended. Use the lowest effective dose for the shortest duration possible. Consult your doctor if you need to use it for more than 10 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help relieve localized pain and inflammation.
Evidence: Well-establishedStress reduction techniques like deep breathing can help manage pain.
Evidence: Some evidence💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination, as fever may be a reason to postpone vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription in case of customs checks. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Do not leave it in a hot car or checked luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to 1 hour after taking it.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.
A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing.
A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as it may increase the risk of side effects.
A: Common side effects include stomach pain, heartburn, nausea, and dizziness. Serious side effects like gastrointestinal bleeding and kidney problems are rare but require immediate medical attention.
🤔 Common Patient Concerns
🔄 Substitutes for ibupol oral suspension
View AllAlternative brands with exact same active ingredient:
-
combikind oral suspensionInnovative Pharmaceuticals ₹20.50 98.8% COSTLIER
-
combitag oral suspensionIkon Remedies Pvt Ltd ₹24.95 142% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: It is safe to take this medicine on an empty stomach.
Fact: Taking it on an empty stomach can increase the risk of stomach upset and bleeding. Always take it with food or milk. - Myth: More medicine means faster relief.
Fact: Taking more than the recommended dose can lead to serious side effects like liver damage and stomach bleeding. Stick to the prescribed dose. - Myth: It can be taken for any type of pain.
Fact: This medicine is effective for mild to moderate pain and fever. For severe pain or specific conditions, consult a doctor for appropriate treatment.
🔄 Alternative Options
Generic Alternatives
- Ibuprofen + Paracetamol oral suspension
Brand Alternatives
- Ibugesic Plus Oral Suspension
- Combiflam Oral Suspension
- Brufen Plus Oral Suspension