Ibudol MR Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or slow, shallow breathing
- Seizures or convulsions
- Severe drowsiness or confusion
- Yellowing of skin or eyes, dark urine
- Severe abdominal pain or vomiting blood
- Signs of allergic reaction: rash, swelling of face, lips, or throat
- Chest pain or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is ibudol mr tablet used for?
This medicine is a combination of chlorzoxazone (a muscle relaxant) and tramadol (an opioid pain reliever) used for short-term relief of moderate to severe musculoskeletal pain with muscle spasm. It is taken orally, usually 1 tablet 2-3 times daily, and should not be used with alcohol or other CNS depressants.
- Generic Name: Chlorzoxazone (250mg) + Tramadol (50mg)
- Manufacturer: Stedman Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ibudol mr tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरज़ोक्साज़ोन और ट्रामाडोल का संयोजन है, जिसका उपयोग मांसपेशियों में ऐंठन और मध्यम से गंभीर दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह मांसपेशियों को आराम देती है और दर्द को कम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मतली, सूखा मुँह और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में सांस लेने में कठिनाई, दौरे, और यकृत की समस्या हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब और अन्य नींद लाने वाली दवाओं से बचें। गाड़ी चलाने या मशीन चलाने से बचें जब तक कि आपको पता न चल जाए कि यह दवा आप पर कैसे असर करती है। यकृत या गुर्दे की बीमारी, दौरे, या अवसादरोधी दवाओं के बारे में अपने डॉक्टर को बताएं।
💊 ibudol mr tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain with muscle spasm","description":"This medicine is used for short-term relief of moderate to severe pain associated with muscle spasm, such as acute low back pain or neck pain.","evidence":"Well-established for short-term use"},{"condition":"Post-traumatic musculoskeletal pain","description":"It may be prescribed after injuries like strains or sprains to relieve pain and associated muscle spasm.","evidence":"Commonly used, evidence from clinical practice"},{"condition":"Post-operative pain with spasm","description":"Sometimes used for short-term management of post-operative pain when muscle spasm is a component.","evidence":"Limited, individualized decision"}]
Off-label uses: [{"condition":"Chronic musculoskeletal pain","description":"Rarely used off-label for chronic pain conditions, but not recommended for long-term use due to dependence and toxicity risks.","evidence":"Limited"},{"condition":"Tension headache with muscle spasm","description":"May be used off-label for tension-type headaches associated with neck muscle spasm, but not first-line.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain with muscle spasm
Also treats: Acute low back pain, Neck pain, Post-traumatic pain
📋 Drug Information
| Generic Name(s) | Chlorzoxazone (250mg) + Tramadol (50mg) |
| Brand Name | ibudol mr tablet |
| Manufacturer | Stedman Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Chlorzoxazone is a centrally acting skeletal muscle relaxant that primarily inhibits polysynaptic reflex pathways in the spinal cord and brain, reducing muscle spasm without directly affecting the neuromuscular junction. Tramadol is a centrally acting opioid analgesic that binds to mu-opioid receptors and also inhibits the reuptake of norepinephrine and serotonin, which contributes to its analgesic effect. Together, they reduce pain and muscle spasm.
Mechanism Steps
💡 How to Take ibudol mr tablet
Strength: Tablet containing Chlorzoxazone 250 mg and Tramadol 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily, or as directed by your doctor. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not exceed the prescribed dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and respiratory depression. Use with caution and lower initial doses may be considered. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, tramadol clearance is reduced. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, chlorzoxazone and tramadol metabolism may be reduced. Dose adjustment or avoidance may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 tablets (750 mg chlorzoxazone and 150 mg tramadol) per day, but the exact maximum must be determined by your doctor based on your condition. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ibudol mr tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| CNS depressants | Major | |
| SSRIs/SNRIs | Major | |
| Warfarin | Moderate | |
| CYP2D6 inhibitors | Moderate | |
| CYP3A4 inducers | Moderate | |
| CYP3A4 inhibitors | Moderate | |
| Anticholinergics | Minor | |
| Antihypertensives | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- MAO inhibitors
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- SSRIs, SNRIs, tricyclic antidepressants
- Warfarin
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of respiratory depression, seizures, and liver toxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to chlorzoxazone, tramadol, or any component of the formulation","Severe liver disease","Severe kidney disease","Uncontrolled epilepsy","Concurrent use of MAO inhibitors","Acute alcohol intoxication","Children under 12 years of age","Pregnancy (unless clearly needed)","Breastfeeding"]
⚠️ Warnings & Precautions
["May cause drowsiness and dizziness; avoid driving or operating machinery until you know how it affects you.","Do not consume alcohol or other CNS depressants.","Use with caution in patients with a history of seizures.","May cause respiratory depression; use with caution in patients with respiratory disease.","Can cause dependence and withdrawal; use for the shortest duration possible.","May increase the risk of serotonin syndrome when used with serotonergic drugs.","Rare cases of severe liver toxicity have been reported with chlorzoxazone.","Do not stop abruptly after prolonged use; taper under medical supervision."]
🤱 Lactation Safety
Tramadol is excreted in breast milk and may cause serious adverse reactions in the nursing infant, including sedation and respiratory depression. Chlorzoxazone is also excreted in breast milk. Breastfeeding is not recommended while taking this medicine.
💊 Overdose Management
Overdose may cause severe drowsiness, respiratory depression, seizures, and cardiac arrest. Seek emergency medical attention immediately. Treatment is supportive and may include naloxone for opioid effects, but naloxone may not fully reverse tramadol toxicity. Monitor vital signs and provide symptomatic care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Avoid alcohol and other central nervous system depressants because they can increase drowsiness and the risk of respiratory depression. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have liver or kidney disease, a history of seizures, or if you are taking antidepressants, antipsychotics, or other pain medicines. Do not stop this medicine suddenly without consulting your doctor, as withdrawal symptoms may occur. Keep this medicine out of reach of children and store it in a cool, dry place.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of this medicine, especially drowsiness, dizziness, and respiratory depression. Lower doses may be required, and close monitoring is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy unless clearly needed and prescribed by a doctor. Tramadol may cause harm to the unborn baby. Discuss with your doctor for alternative pain management.
🏥 Post-Surgery Considerations
This medicine may be used for short-term post-operative pain with muscle spasm, but it should be prescribed by a surgeon or anesthesiologist. It can increase the risk of respiratory depression, especially when combined with other sedatives.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may interact with anesthetics and other medications used during dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that require alertness while taking this medicine, as it can cause drowsiness and dizziness. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. Avoid these activities until you know how the medicine affects you. Inform your employer if your job involves such tasks.
🛑 When to Stop This Medicine
Stop this medicine and consult your doctor immediately if you experience serious side effects such as difficulty breathing, seizures, severe skin rash, or yellowing of eyes or skin. Do not stop abruptly after prolonged use without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to dependence, tolerance, and withdrawal symptoms. It may also increase the risk of liver toxicity, respiratory depression, and serotonin syndrome. Regular monitoring of liver and kidney function is advised. Use for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and muscle spasm.
Evidence: Well-establishedMay help relieve muscle spasm and pain.
Evidence: Commonly usedMay provide pain relief for some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccination timing while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from light and moisture. If traveling across time zones, adjust dosing times gradually under medical advice. Check customs regulations for controlled substances before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking it.
A: Yes, taking it with food can help reduce stomach upset.
A: No, this medicine can cause drowsiness and dizziness. Avoid driving or operating machinery until you know how it affects you.
A: Do not stop suddenly after prolonged use as it can cause withdrawal symptoms. Consult your doctor for a tapering schedule.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: This medicine is intended for short-term use only. Long-term use can lead to dependence, liver toxicity, and other serious side effects. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol increases the risk of severe drowsiness, respiratory depression, and liver damage. It should be avoided completely. - Myth: This medicine can be taken without a prescription.
Fact: This is a prescription-only medicine and must be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Chlorzoxazone 250 mg + Tramadol 50 mg tablet (generic)
Brand Alternatives
- Ibudol MR Tablet