ibu m tablet - Ibuprofen (325mg) + Paracetamol (400mg) medicine

Ibu M Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Alpic Remedies Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, NSAIDs like ibuprofen are generally avoided in the third trimester due to risk of premature closure of the ductus arteriosus and other complications. Paracetamol is considered relatively safe during pregnancy when used at recommended doses. Consult your doctor before taking this medicine during pregnancy. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term use.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is ibu m tablet used for?

This medicine is a combination of ibuprofen and paracetamol used for short-term relief of mild to moderate pain and fever. It works by reducing pain and inflammation. Take it with food and do not exceed 3 tablets in 24 hours.

  • Generic Name: Ibuprofen (325mg) + Paracetamol (400mg)
  • Manufacturer: Alpic Remedies Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ibu m tablet के बारे में (Hindi Summary)

उपयोग: यह दवा इबुप्रोफेन और पैरासिटामोल का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार से राहत के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मांसपेशियों में दर्द, पीठ दर्द, मासिक धर्म में होने वाले दर्द और बुखार में प्रभावी है। यह दवा सूजन को भी कम करती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, दस्त, चक्कर आना और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में अल्सर, रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, आंखों या त्वचा का पीलापन, पेशाब में कमी, चेहरे या गले में सूजन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें और निर्देशित अवधि से अधिक समय तक उपयोग न करें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की क्षति का खतरा बढ़ सकता है। पैरासिटामोल या अन्य NSAIDs वाली दवाओं को बिना डॉक्टर की सलाह के न लें। यदि आपको पेट में अल्सर, गुर्दे या यकृत की बीमारी, हृदय रोग या अस्थमा है तो डॉक्टर को बताएं। गर्भावस्था के तीसरे तिमाही में इस दवा का उपयोग न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 ibu m tablet Uses & Benefits

[{"condition":"Mild to moderate pain","description":"This medicine provides relief from various types of acute pain such as headache, toothache, muscle ache, back pain, and menstrual cramps.","evidence":"Well-established"},{"condition":"Fever","description":"The paracetamol component helps reduce fever, while ibuprofen also contributes to lowering body temperature.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Short-term use may help relieve pain and improve joint mobility in osteoarthritis, but long-term use should be avoided due to NSAID risks.","evidence":"Established for short-term use"},{"condition":"Dental pain","description":"Effective for relieving pain after dental procedures or from dental infections.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"May be used for short-term management of mild to moderate post-surgical pain under medical supervision.","evidence":"Established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not as a first-line treatment.","evidence":"Limited"},{"condition":"Sore throat","description":"Can be used off-label for symptomatic relief of sore throat pain.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Headache, Dental pain, Menstrual cramps, Muscle aches, Back pain, Osteoarthritis

📋 Drug Information

Generic Name(s)Ibuprofen (325mg) + Paracetamol (400mg)
Brand Nameibu m tablet
ManufacturerAlpic Remedies Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to minimize stomach irritation.
2
Do not exceed the maximum daily dose of 3 tablets in 24 hours.
3
Avoid alcohol completely while taking this medicine to prevent liver damage and stomach bleeding.
4
If you are taking blood thinners like warfarin, inform your doctor before using this medicine.
5
Do not use this medicine for more than 3 days for fever or 10 days for pain without medical advice.
6
Stay well hydrated throughout the day to support kidney function.
7
Report any signs of unusual bleeding, bruising, or persistent stomach pain to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Headache
This medicine is commonly used for headache relief.
Likely Use
✅
Fever
This medicine helps reduce fever.
Likely Use
✅
Muscle pain
This medicine is effective for muscle aches.
Likely Use
❌
Chest pain
Chest pain requires immediate medical attention and is not treated with this medicine.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionIbuprofen is rapidly absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations occurring within 1 to 2 hours. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract, with peak plasma levels within 0.5 to 2 hours. Food may delay the absorption of both drugs but does not significantly reduce the extent of absorption.
DistributionIbuprofen is highly bound to plasma proteins and distributes into synovial fluid, cerebrospinal fluid, and breast milk. Paracetamol distributes widely into most body tissues, with a volume of distribution of about 0.9 L/kg. Both drugs cross the placenta.
Protein BindingIbuprofen is approximately 99% bound to plasma proteins, primarily albumin. Paracetamol is only about 10-25% bound to plasma proteins.
MetabolismIbuprofen is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP2C9, to inactive metabolites. Paracetamol is metabolized in the liver primarily by glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of ibuprofen is approximately 2 hours. The elimination half-life of paracetamol is about 2 to 3 hours.
ExcretionIbuprofen metabolites are excreted primarily in the urine. Paracetamol metabolites are also excreted in the urine, with about 90% of the dose eliminated within 24 hours.
BioavailabilityThe oral bioavailability of ibuprofen is approximately 80-90%. Paracetamol has an oral bioavailability of about 80-100%.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimeIbuprofen peak plasma concentration occurs at 1-2 hours; paracetamol peak plasma concentration occurs at 0.5-2 hours.
Duration of ActionThe analgesic and antipyretic effects last for approximately 4 to 6 hours.

How It Works

This medicine combines two active ingredients with different mechanisms. Ibuprofen is a non-selective cyclooxygenase (COX) inhibitor that reversibly blocks both COX-1 and COX-2 enzymes, reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol's mechanism is not fully understood, but it is believed to act primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, leading to pain relief and fever reduction. The combination provides additive analgesic and antipyretic effects.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: Ibuprofen reversibly inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: This leads to decreased levels of prostaglandins, which are responsible for pain, inflammation, and fever.
3
Central analgesic action of paracetamol: Paracetamol acts mainly in the brain and spinal cord to inhibit prostaglandin synthesis and modulate pain perception.
4
Additive analgesic and antipyretic effect: The combined actions of ibuprofen and paracetamol result in enhanced pain relief and fever reduction compared to either alone.

💡 How to Take ibu m tablet

Strength: Ibuprofen 325 mg + Paracetamol 400 mg immediate-release tablet.

1Take this medicine by mouth with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole. Do not crush or chew.
4Follow the prescribed dose and duration.
5Do not take more than 3 tablets in 24 hours.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 6 to 8 hours as needed for pain or fever. Do not exceed 3 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not take for more than 3 days for fever or 10 days for pain without consulting a doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration possible. Consult a doctor for appropriate dosing.
Renal ImpairmentUse with caution in patients with kidney disease. Dose reduction may be necessary. Consult a doctor for appropriate dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction may be necessary. Consult a doctor for appropriate dosing.
Maximum Daily DoseThe maximum daily dose is 3 tablets in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or milk
Reduces stomach upset and irritation.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver damage.
Caffeine
Limit excessive intake
May increase nervousness and insomnia.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ibu m tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Stomach pain (Common (5-10%))
Take with food or milk. Avoid alcohol. If pain is severe or persistent, seek medical advice.
Heartburn (Common (5-10%))
Take with food. Avoid lying down immediately after taking. Consult doctor if it continues.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how this medicine affects you.
Headache (Uncommon (1-5%))
Usually resolves on its own. If persistent, consult your doctor.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.
Stomach ulcer (Rare (<0.1%))
Report persistent stomach pain, indigestion, or nausea to your doctor immediately.
Liver damage (Rare (<0.1%))
Seek medical help if you experience yellowing of skin or eyes, dark urine, or severe fatigue.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor.
Severe allergic reaction (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, fever, and sensitivity to light.
Blood disorders
Report unusual bruising or bleeding, sore throat, or fever to your doctor.
Pancreatitis
Seek medical help if you have severe abdominal pain radiating to the back, with nausea and vomiting.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Methotrexate Major
ACE inhibitors Major
Diuretics Major
Corticosteroids Moderate
SSRIs Moderate
Lithium Moderate
Phenytoin Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., aspirin, naproxen)
  • Methotrexate
  • ACE inhibitors and ARBs
  • Diuretics

⚡ Moderate Interactions

  • Corticosteroids
  • SSRIs
  • Lithium
  • Phenytoin

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver damage, especially with paracetamol. It can also increase drowsiness and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney disease","Severe liver disease","Aspirin-sensitive asthma or allergic reaction to NSAIDs","Third trimester of pregnancy","Children under 12 years of age"]

⚠️ Warnings & Precautions

["Take with food or milk to reduce stomach upset.","Do not exceed the recommended dose or duration of treatment.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of side effects.","Consult your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma.","Do not use this medicine for more than 3 days for fever or 10 days for pain without medical advice.","Stop use and consult a doctor if pain or fever worsens or persists.","Keep out of reach of children."]

🤱 Lactation Safety

Ibuprofen and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage, gastrointestinal bleeding, and kidney failure. Symptoms of overdose include nausea, vomiting, abdominal pain, drowsiness, and confusion. If you suspect an overdose, seek immediate medical attention or contact a poison control center. Treatment may include activated charcoal, gastric lavage, and administration of acetylcysteine for paracetamol toxicity. Supportive care and monitoring of liver and kidney function are essential.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than directed. Take each dose with a full glass of water and preferably with food or milk to reduce stomach irritation. Avoid drinking alcohol while taking this medicine because it can increase the risk of stomach bleeding and liver damage. Do not take other medicines containing paracetamol or other NSAIDs without consulting your doctor, as this can lead to overdose or increased side effects. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma, inform your doctor before taking this medicine. Do not use this medicine during the third trimester of pregnancy without medical advice. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration possible. Consult a doctor for appropriate dosing and monitoring.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like ibuprofen may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

This medicine may be used for short-term post-operative pain management under medical supervision. However, it may increase the risk of bleeding, so inform your surgeon if you are taking it before surgery.

🦷 Dental Procedures

This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and muscles.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice good posture to prevent back and neck pain.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 fatty acids in your diet.
🧘
Get adequate sleep to help your body recover.
🌞
Stay well hydrated by drinking plenty of water.

🏋️ Exercise Considerations

If you experience dizziness or fatigue while taking this medicine, avoid strenuous exercise or activities that require alertness. Listen to your body and rest if needed.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Eat plenty of fruits and vegetables.
Stay well hydrated with water and clear fluids.
Limit caffeine and alcohol consumption.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe for office work, but take breaks and stay hydrated.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your pain or fever persists beyond 3 days (for fever) or 10 days (for pain), if you experience severe side effects, or if you develop signs of gastrointestinal bleeding, liver problems, or allergic reactions.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and cardiovascular events. It should only be used for short-term relief unless otherwise directed by a doctor. Regular monitoring of kidney and liver function may be required with prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help manage chronic pain and improve mobility without medication.

Evidence: Well-established
Hot and cold therapy

Applying heat or cold packs can relieve muscle pain and inflammation.

Evidence: Established
Relaxation techniques

Deep breathing, meditation, and yoga can help reduce pain perception.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription to avoid issues at customs. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking the medicine as needed for pain or fever, but do not exceed the maximum daily dose. Keep it in your carry-on luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with severe menstrual cramps
She was prescribed this medicine for menstrual pain. She took one tablet with food when the pain started and experienced relief within 45 minutes. She made sure not to exceed 3 tablets in a day and avoided alcohol. She reported no stomach upset.
💡 Lesson: Taking the medicine with food and adhering to the maximum daily dose provides effective pain relief with minimal side effects.
👤 A 50-year-old man with dental pain after a tooth extraction
He was given this medicine for post-extraction pain. He took it as prescribed every 8 hours with meals. The pain was well controlled, and he did not experience any stomach issues. He was advised not to take additional paracetamol.
💡 Lesson: Following the prescribed schedule and avoiding additional paracetamol prevents overdose and ensures safe pain management.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take it with other NSAIDs or paracetamol-containing products without consulting your doctor, as it can increase the risk of side effects.

Q: Can I take it during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy, especially in the third trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ibu m tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe to take on an empty stomach.
    Fact: It should be taken with food or milk to reduce stomach upset.
  • Myth: This medicine can be taken for long periods without any risk.
    Fact: Long-term use can cause serious side effects like stomach bleeding and kidney problems.
  • Myth: This medicine is safe to take with other painkillers.
    Fact: Taking it with other NSAIDs or paracetamol-containing products can lead to overdose and serious side effects.

🔄 Alternative Options

Generic Alternatives

  • Ibuprofen + Paracetamol combination tablets from other manufacturers

Brand Alternatives

  • Combiflam
  • Brufen Plus
  • Ibugesic Plus
  • Flexon
  • Doloflam

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ibuprofen 325 mg + Paracetamol 400 mg","onset":"30-60 minutes","duration":"4-6 hours","prescription":true},{"medicine":"Paracetamol alone","composition":"Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","prescription":false},{"medicine":"Ibuprofen alone","composition":"Ibuprofen 400 mg","onset":"30-60 minutes","duration":"4-6 hours","prescription":false}]

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