Floresp Nasal Spray (Fluticasone Propionate 27.5mcg): Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or persistent nosebleeds
- Pain or swelling around the eyes or cheeks
- Vision changes or eye pain
- Difficulty breathing or swelling of the face, lips, or throat
- Signs of infection such as fever, severe headache, or rash
- No improvement after 2-3 weeks of use
If experiencing severe symptoms, call emergency services immediately.
What is ibinase nasal spray used for?
This medicine is a nasal spray containing fluticasone propionate, a corticosteroid used to treat allergic rhinitis and nasal polyps. It reduces nasal inflammation and relieves sneezing, runny nose, and congestion. It is used once or twice daily as prescribed.
- Generic Name: Fluticasone Propionate (27.5mcg)
- Manufacturer: Indiabulls pharmaceutical ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ibinase nasal spray के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लूटिकासोन प्रोपियोनेट नामक स्टेरॉयड की नाक स्प्रे है। इसका उपयोग एलर्जिक राइनाइटिस (नाक की एलर्जी) और नाक के पॉलीप्स के इलाज के लिए किया जाता है। यह नाक में सूजन को कम करती है और छींक, बहती नाक, खुजली और नाक बंद होने से राहत देती है। यह दवा 4 साल से बड़े बच्चों और वयस्कों के लिए है। इसे डॉक्टर के बताए अनुसार ही इस्तेमाल करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में नाक में जलन, सूखापन, खुजली, नाक से खून आना, सिरदर्द और गले में खराश शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर नाक से लगातार खून आए, आंखों में दर्द या धुंधलापन हो, या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा का इस्तेमाल डॉक्टर के बताए अनुसार ही करें। ज्यादा मात्रा में या लंबे समय तक बिना सलाह के इस्तेमाल न करें। स्प्रे करने से पहले नाक साफ करें और बोतल को हल्का हिलाएं। सिर को थोड़ा आगे झुकाएं और स्प्रे को नाक में डालकर धीरे से सांस लें। आंखों में स्प्रे न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। ठंडी और सूखी जगह पर स्टोर करें।
💊 ibinase nasal spray Uses & Benefits
[{"condition":"Seasonal allergic rhinitis","description":"Relieves sneezing, runny nose, itchy nose, and nasal congestion caused by pollen allergies.","evidence":"Well-established"},{"condition":"Perennial allergic rhinitis","description":"Treats year-round allergy symptoms caused by dust mites, pet dander, or mold.","evidence":"Well-established"},{"condition":"Non-allergic rhinitis","description":"May help reduce nasal inflammation and congestion in non-allergic rhinitis.","evidence":"Moderate"},{"condition":"Nasal polyps","description":"Used to shrink nasal polyps and prevent their recurrence after surgery.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Eosinophilic esophagitis","description":"Sometimes used off-label by swallowing the spray to treat inflammation in the esophagus.","evidence":"Limited"},{"condition":"Chronic rhinosinusitis","description":"May be used off-label to reduce nasal inflammation in chronic sinusitis.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Non-allergic rhinitis, Nasal polyps
📋 Drug Information
| Generic Name(s) | Fluticasone Propionate (27.5mcg) |
| Brand Name | ibinase nasal spray |
| Manufacturer | Indiabulls pharmaceutical ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Glucocorticoids |
| Route of Administration | Intranasal |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. Keep the bottle upright. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Fluticasone propionate is a synthetic corticosteroid with high affinity for the glucocorticoid receptor. When sprayed into the nose, it binds to these receptors in the nasal mucosa and reduces the production of inflammatory mediators such as histamine, prostaglandins, and leukotrienes. This leads to a decrease in the number of inflammatory cells, including mast cells, eosinophils, and lymphocytes, in the nasal lining. As a result, symptoms of allergy such as sneezing, itching, and congestion are relieved. The anti-inflammatory effect is local and does not cause immediate vasoconstriction like decongestants.
Mechanism Steps
💡 How to Take ibinase nasal spray
Strength: Nasal spray, 27.5 mcg per spray
Dosage Information
| Adult Dosage | The usual adult dose for allergic rhinitis is 1 to 2 sprays (27.5 mcg per spray) in each nostril once daily, or as prescribed. For nasal polyps, the dose may be 1 to 2 sprays in each nostril once or twice daily. The dose must be individualized by a qualified clinician based on indication, age, and response to treatment. Do not exceed the recommended dose. |
| Pediatric Dosage | For children aged 4 to 11 years with allergic rhinitis, the usual dose is 1 spray (27.5 mcg) in each nostril once daily. For children 12 years and older, the adult dose may be used. Pediatric dosing is not established for children under 4 years. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients. However, use with caution and monitor for side effects. |
| Renal Impairment | No dose adjustment is required for patients with renal impairment. |
| Hepatic Impairment | Use with caution in patients with severe hepatic impairment as systemic exposure may increase. No specific dose adjustment is established. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 sprays in each nostril once daily (total 110 mcg per day) for adults. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ibinase nasal spray
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Ritonavir | Major | |
| Prednisone | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
⚡ Moderate Interactions
- Other corticosteroids (oral, inhaled, topical)
🍷 Alcohol Interaction
Alcohol is not known to interact directly with this medicine. However, alcohol can worsen nasal congestion and may dry out the nasal passages. It is advisable to limit alcohol intake while using this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to fluticasone propionate or any component of the formulation","Untreated nasal infections (e.g., herpes simplex)","Recent nasal surgery or trauma until healing occurs","Children under 4 years of age for allergic rhinitis (safety not established)"]
⚠️ Warnings & Precautions
["Do not use for acute asthma attacks or breathing problems.","Avoid contact with eyes. If contact occurs, rinse thoroughly with water.","Use with caution in patients with active or latent tuberculosis, or untreated fungal, bacterial, or viral infections.","Long-term use may cause systemic corticosteroid effects, especially at high doses.","In children, growth should be monitored regularly.","If symptoms do not improve after 2-3 weeks, consult your doctor.","Do not share this medicine with others."]
🤱 Lactation Safety
It is not known whether fluticasone propionate passes into breast milk in significant amounts. However, systemic absorption is low, so it is unlikely to harm a nursing infant. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with intranasal fluticasone propionate is unlikely due to low systemic absorption. If large amounts are ingested or sprayed, seek medical attention. Symptoms of overdose may include signs of hypercortisolism. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Use this medicine exactly as prescribed. Do not use more often or for longer than recommended. Before using, gently shake the bottle and prime it if it is new or has not been used for a week. Blow your nose gently to clear the nostrils. Tilt your head slightly forward and insert the nozzle into one nostril, aiming away from the center of the nose. Breathe in gently through the nose and spray. Do not sniff hard, as this may cause the medicine to go down your throat. Avoid spraying into the eyes or mouth. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine if you have a nasal infection or after nasal surgery without your doctor's advice. Keep out of reach of children. Store at room temperature, away from direct sunlight and moisture. Do not freeze. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to systemic effects of corticosteroids. Use with caution and monitor for side effects such as increased eye pressure and bone loss.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It is generally considered safe in pregnancy when used as directed, but your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Do not use this medicine immediately after nasal surgery without your doctor's approval. It may interfere with healing. Follow your surgeon's instructions.
🦷 Dental Procedures
No specific precautions are needed for dental procedures. However, inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions are needed while using this medicine. However, if you experience dizziness or headache, avoid strenuous activities until you feel better.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. It is not sedating. You can continue your normal work and daily activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor, especially if you have been using it for a long time. If you experience serious side effects, contact your doctor immediately. Your doctor may taper the dose gradually if needed.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when used as prescribed. However, high doses or prolonged use may lead to systemic corticosteroid effects such as adrenal suppression, growth retardation in children, and increased eye pressure. Regular monitoring by a doctor is recommended for long-term users.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help clear allergens and moisturize nasal passages.
Evidence: Well-establishedAlternative for allergic rhinitis if corticosteroids are not suitable.
Evidence: Well-establishedLong-term treatment that can reduce allergy symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are on high doses for a long time, consult your doctor before receiving live vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in your carry-on luggage to avoid extreme temperatures. If traveling across time zones, continue your regular dosing schedule. Check customs regulations for prescription medicines in your destination country. Keep the bottle upright and protect it from direct sunlight.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some relief may be noticed within 12 hours, but full effect usually takes 1 to 2 weeks of regular use.
A: No, this medicine is for allergic rhinitis and nasal polyps, not for colds or infections.
A: It is approved for children 4 years and older for allergic rhinitis. Consult a pediatrician for younger children.
A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for ibinase nasal spray
View AllAlternative brands with exact same active ingredient:
-
morspre 27.5mcg nasal dropsPrecept Pharma Ltd ₹253.13 11.5% CHEAPER
-
furaspray 27.5mcg nasal sprayCipla Ltd ₹254.07 11.1% CHEAPER
-
flutirest 27.5mcg nasal sprayCentaur Pharmaceuticals Pvt Ltd ₹271.75 5% CHEAPER
-
filson 27.5mcg nasal sprayBiochemix Health Care Pvt. Ltd. ₹280.31 2% CHEAPER
-
flavson 27.5mcg nasal sprayNovaMed Pharmaceuticals Pvt Ltd ₹280.31 2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine works immediately.
Fact: It may take several days to weeks for full effect. - Myth: It is addictive.
Fact: This medicine is not addictive. - Myth: It can be used for any nasal congestion.
Fact: It is specifically for allergic rhinitis and nasal polyps, not for infections.
🔄 Alternative Options
Generic Alternatives
- Fluticasone propionate nasal spray (generic)
Brand Alternatives
- Floresp nasal spray