Diplowax Lotion: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat, or difficulty breathing.
- Severe burning, blistering, or peeling of the skin.
- Signs of adrenal suppression: extreme tiredness, weakness, dizziness, nausea, or weight loss.
- Ringing in the ears, dizziness, or nausea (possible salicylate toxicity).
- Increased pain, warmth, swelling, or pus at the application site (sign of infection).
- Yellowing of the skin or eyes (jaundice).
- Unusual weight gain, round face, or increased thirst (signs of Cushing's syndrome).
If experiencing severe symptoms, call emergency services immediately.
What is i salic cp lotion used for?
This medicine is a prescription lotion containing clobetasol 0.05% and salicylic acid 2%. It is used to treat thick, scaly, inflamed skin conditions like psoriasis and severe eczema. Apply a thin film to the affected area once or twice daily for up to 2 weeks, or as directed by your doctor.
- Generic Name: Clobetasol (0.05% w/v) + Salicylic Acid (2% w/v)
- Manufacturer: MRHM Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 i salic cp lotion के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल लोशन है जिसमें क्लोबेटासोल 0.05% और सैलिसिलिक एसिड 2% होता है। इसका उपयोग सोरायसिस, गंभीर एक्जिमा और अन्य सूजन वाली त्वचा की बीमारियों के इलाज के लिए किया जाता है। यह खुजली, लालिमा और पपड़ी को कम करने में मदद करता है। इसे डॉक्टर के निर्देशानुसार ही लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, सूखापन और लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है और खिंचाव के निशान पड़ सकते हैं। दुर्लभ मामलों में एलर्जी, चक्कर आना या कान में आवाज हो सकती है। कोई भी गंभीर लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल त्वचा पर ही लगाएं। आंखों, मुंह और नाक से दूर रखें। चेहरे, बगल और जांघ के जोड़ पर बिना डॉक्टर की सलाह के न लगाएं। 2 सप्ताह से अधिक लगातार उपयोग न करें। बच्चों को 12 साल से कम उम्र में न लगाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को आग से दूर रखें क्योंकि यह ज्वलनशील है।
💊 i salic cp lotion Uses & Benefits
[{"condition":"Plaque psoriasis","description":"Helps to reduce thick scaling, redness, and inflammation of psoriatic plaques.","evidence":"Well-established"},{"condition":"Severe eczema (atopic dermatitis)","description":"Provides relief from intense itching, redness, and scaling in flare-ups.","evidence":"Well-established"},{"condition":"Lichen simplex chronicus","description":"Reduces thickened, leathery skin caused by chronic rubbing and scratching.","evidence":"Moderate"},{"condition":"Seborrheic dermatitis of the scalp","description":"Helps control scaling and inflammation on the scalp.","evidence":"Moderate"},{"condition":"Discoid lupus erythematosus","description":"Used for localized skin lesions to reduce inflammation and scaling.","evidence":"Limited"}]
Off-label uses: [{"condition":"Alopecia areata","description":"Sometimes used on the scalp to reduce inflammation and promote hair regrowth.","evidence":"Limited"},{"condition":"Vitiligo","description":"Occasionally used to reduce inflammation in active vitiligo patches.","evidence":"Limited"},{"condition":"Hypertrophic scars and keloids","description":"May help soften and flatten raised scars when used under medical supervision.","evidence":"Limited"}]
Primary treatment for: Plaque psoriasis
Also treats: Severe eczema, Lichen simplex chronicus, Seborrheic dermatitis, Discoid lupus erythematosus
📋 Drug Information
| Generic Name(s) | Clobetasol (0.05% w/v) + Salicylic Acid (2% w/v) |
| Brand Name | i salic cp lotion |
| Manufacturer | MRHM Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature, below 30°C. Do not freeze. Keep the bottle tightly closed. Protect from direct sunlight and heat. Keep away from open flames. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a superpotent corticosteroid with a keratolytic agent. Clobetasol binds to glucocorticoid receptors inside skin cells, which leads to a decrease in the production of inflammatory chemicals such as prostaglandins and leukotrienes. This reduces redness, swelling, itching, and the rapid turnover of skin cells seen in psoriasis. Salicylic acid works by breaking down the bonds between dead skin cells, which helps to soften and remove thick scales. This allows the clobetasol to penetrate better into the skin and also directly reduces scaling. The combination is more effective for thick, scaly lesions than either ingredient alone.
Mechanism Steps
💡 How to Take i salic cp lotion
Strength: Lotion containing clobetasol 0.05% w/v and salicylic acid 2% w/v.
Dosage Information
| Adult Dosage | Apply a thin film of this medicine to the affected area once or twice daily, or as directed by your doctor. The usual duration of treatment is up to 2 weeks. Do not use more than 50 grams per week. Dose must be individualized by a qualified clinician based on the condition being treated, the area of skin involved, and your response to therapy. Do not use on the face, groin, or underarms unless specifically instructed. Wash your hands after applying, unless your hands are the treated area. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 12 years of age due to the risk of systemic absorption and adrenal suppression. |
| Elderly Dosage | Elderly patients may be more susceptible to the side effects of topical corticosteroids, especially skin thinning and systemic absorption. Use the smallest effective amount for the shortest duration. Consult your doctor for individualized dosing. |
| Renal Impairment | No specific dose adjustment is established for topical use. However, if you have severe kidney disease, use with caution and consult your doctor, as salicylic acid is excreted by the kidneys. |
| Hepatic Impairment | No specific dose adjustment is established for topical use. However, if you have severe liver disease, use with caution and consult your doctor, as both ingredients are metabolized in the liver. |
| Maximum Daily Dose | Do not exceed 50 grams of lotion per week. The maximum daily dose depends on the concentration and area treated, but generally should not exceed 7 grams per day. Always follow your doctor's prescription. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of i salic cp lotion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Prednisone | Major | |
| Methotrexate | Moderate | |
| Insulin | Moderate | |
| Furosemide | Moderate | |
| Tretinoin | Minor | |
| Tacrolimus | Minor |
🚨 Major Interactions
- Other topical corticosteroids
- Oral corticosteroids (e.g., prednisone)
- Anticoagulants (e.g., warfarin)
⚡ Moderate Interactions
- Methotrexate
- Insulin or oral antidiabetics
- Diuretics (e.g., furosemide)
🍷 Alcohol Interaction
No direct interaction is expected from topical use. However, if this medicine is absorbed significantly, alcohol may increase the risk of stomach irritation. It is best to avoid excessive alcohol while using this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to clobetasol, salicylic acid, or any ingredient in the lotion","Untreated bacterial, fungal, or viral skin infections (e.g., impetigo, ringworm, herpes)","Acne vulgaris, rosacea, or perioral dermatitis","Use on the face, groin, or underarms unless specifically directed by a doctor","Use in children under 12 years of age unless prescribed by a doctor","Use on open wounds or broken skin"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas of the body or for longer than 2 weeks without medical advice.","Do not use under airtight dressings unless instructed by a doctor.","Flammable: keep away from fire or flame.","If you are pregnant or breastfeeding, consult your doctor before use.","Do not use on children under 12 years without medical advice.","If symptoms do not improve after 2 weeks, stop and consult a doctor.","Do not use for any condition other than the one prescribed.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether clobetasol or salicylic acid passes into breast milk in significant amounts after topical use. To be safe, do not apply this medicine to the breast area, and avoid applying it to large areas while breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose from topical application is unlikely. If the lotion is accidentally swallowed, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, dizziness, ringing in the ears, and in severe cases, adrenal suppression. Treatment is supportive and symptomatic. Contact a poison control center or emergency room right away.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine exactly as prescribed by your doctor. Wash your hands before and after applying it, unless your hands are the treated area. Clean and dry the affected skin gently before applying a thin film of the lotion. Do not cover the treated area with tight dressings, plastic wraps, or bandages unless your doctor tells you to, because this can increase absorption and side effects. Avoid getting the lotion in your eyes, mouth, nose, or on your genitals. If it accidentally gets into these areas, rinse with plenty of water. Do not use this medicine on the face, underarms, or groin unless specifically instructed. Do not use it for more than the recommended duration, usually no longer than two weeks without a break. Do not use it on children under 12 years of age unless a doctor prescribes it. Keep the lotion away from open flames because it contains alcohol and is flammable. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not share this medicine with anyone else, even if they have the same symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to skin thinning and systemic side effects from topical corticosteroids. Use the smallest effective amount for the shortest duration. Monitor for signs of adrenal suppression, high blood sugar, and high blood pressure. Consult your doctor regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Topical corticosteroids should be used during pregnancy only if clearly needed. Use the smallest amount for the shortest time, and avoid applying to large areas.
🏥 Post-Surgery Considerations
If you have recently had surgery, do not apply this medicine to surgical wounds or broken skin unless your surgeon specifically instructs you to. It can interfere with wound healing and increase the risk of infection.
🦷 Dental Procedures
This medicine is applied to the skin and is not expected to affect dental procedures. However, inform your dentist about all medicines you are using, especially if you are taking oral steroids or anticoagulants.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while using this medicine. However, if you have open sores or severe skin irritation, avoid activities that cause excessive sweating or friction on the affected areas. Swimming in chlorinated pools may irritate the skin; rinse off with fresh water afterward and apply a moisturizer.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied to the skin and is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or ringing in the ears (rare side effects), avoid driving or operating heavy machinery until you feel normal. The lotion may leave a slight residue on clothing; allow it to dry before dressing.
🛑 When to Stop This Medicine
Stop using this medicine after the prescribed duration, usually no more than 2 weeks, unless your doctor tells you otherwise. If your symptoms do not improve within 2 weeks, or if they worsen, stop and consult your doctor. Do not stop abruptly if you have been using it for a long time without consulting your doctor, as this may cause a flare-up.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to skin thinning, stretch marks, visible blood vessels, and increased risk of skin infections. It can also cause systemic effects such as adrenal suppression, high blood sugar, and high blood pressure if absorbed in significant amounts. To minimize these risks, use the smallest effective amount for the shortest duration, and take breaks between courses. Regular follow-up with your doctor is recommended if you need repeated courses.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Regular use of moisturizers helps soothe dry, scaly skin and reduce itching.
Evidence: Well-establishedControlled exposure to ultraviolet light can help control psoriasis and eczema.
Evidence: Well-establishedCoal tar can reduce scaling and inflammation, often used as an alternative or adjunct.
Evidence: ModerateFor severe psoriasis, injectable biologics target specific immune pathways.
Evidence: Well-established for severe disease💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction between this topical medicine and vaccines is established. However, if you are using this medicine over large areas or for a long time, it may suppress your immune system slightly. Consult your doctor before receiving any live vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in the original container with the cap tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and heat
❌ DON'T
Do not store in the bathroom cabinet or near a stove
✅ DO
Keep away from open flames
❌ DON'T
Do not puncture or incinerate the container
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and heat. If you are traveling across time zones, continue applying it as prescribed; there is no need to adjust the schedule for topical medicines. Do not leave it in a hot car.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice reduced itching and redness within a few days, but significant improvement in scaling and plaque thickness usually takes 1 to 2 weeks of regular use.
A: No, unless your doctor specifically tells you to. The skin on the face is thin and more likely to absorb the medicine, increasing the risk of side effects like thinning and stretch marks.
A: If you remember within a few hours, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
A: This medicine is generally not recommended for children under 12 years of age unless prescribed by a doctor, because children are more susceptible to systemic absorption and side effects.
A: Consult your doctor before use. Do not apply it to the breast area, and avoid using it on large areas while breastfeeding.
🤔 Common Patient Concerns
🔄 Substitutes for i salic cp lotion
View AllAlternative brands with exact same active ingredient:
-
diplowax lotionLeeford Healthcare Ltd ₹60.00 60.7% CHEAPER
-
jasalic lotionAja Life ₹70.31 54% CHEAPER
-
plecikoid s lotionPretium Pharmaceuticals ₹90.00 41.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any skin rash.
Fact: This medicine is a superpotent steroid and should only be used for specific conditions prescribed by a doctor. Using it for the wrong rash can worsen conditions like acne or fungal infections. - Myth: More medicine means faster healing.
Fact: Applying more than prescribed increases the risk of side effects like skin thinning and systemic absorption. Always use a thin film as directed. - Myth: It is safe to use on the face.
Fact: This medicine should not be used on the face unless specifically directed by a doctor, because facial skin is thin and more prone to side effects. - Myth: You can stop using it as soon as the skin looks better.
Fact: Stopping suddenly may cause a flare-up. Follow your doctor's instructions on how long to use it and how to taper off if needed.
🔄 Alternative Options
Generic Alternatives
- Clobetasol propionate 0.05% + Salicylic acid 2% lotion (generic)
Brand Alternatives
- Diplowax Lotion