Aviron 50mg Injection: Comprehensive Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or wheezing
- Swelling of the face, lips, tongue, or throat
- Severe chest pain or tightness
- Sudden drop in blood pressure with fainting
- Severe rash or hives
- High fever with chills
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is i plus 50mg injection used for?
This medicine is an intravenous iron preparation used to treat iron deficiency anaemia when oral iron is not effective or tolerated. It works by replenishing iron stores, which are essential for haemoglobin production.
- Generic Name: Iron Sucrose (50mg)
- Manufacturer: Bayberry Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 i plus 50mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा आयरन सुक्रोज इंजेक्शन है, जिसका उपयोग आयरन की कमी से होने वाले एनीमिया के इलाज के लिए किया जाता है, खासकर उन रोगियों में जिन्हें मुंह से ली जाने वाली आयरन दवाएं प्रभावी नहीं लगतीं या सहन नहीं होतीं। यह दवा गुर्दे की बीमारी, डायलिसिस, भारी मासिक धर्म, या पाचन तंत्र की समस्याओं वाले रोगियों के लिए उपयोगी है। यह शरीर में आयरन के भंडार को फिर से भरने में मदद करती है, जिससे हीमोग्लोबिन का उत्पादन बढ़ता है और एनीमिया में सुधार होता है। यह दवा केवल डॉक्टर की देखरेख में अस्पताल या क्लिनिक में दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, सिरदर्द, चक्कर आना, और इंजेक्शन की जगह पर दर्द या सूजन शामिल हैं। कुछ मामलों में रक्तचाप में गिरावट, तेज धड़कन, या एलर्जी की प्रतिक्रिया हो सकती है। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है लेकिन तत्काल चिकित्सा की आवश्यकता होती है। अगर आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर चकत्ते दिखें, तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। इससे पहले कि आपको यह दवा दी जाए, अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों, एलर्जी, गर्भावस्था, या स्तनपान के बारे में बताएं। यदि आपको आयरन की अधिकता या लीवर की गंभीर बीमारी है, तो यह दवा न लें। इंजेक्शन के दौरान किसी भी असामान्य लक्षण को तुरंत बताएं। इंजेक्शन के बाद कम से कम 30 मिनट तक निगरानी में रहें। ड्राइविंग या मशीन चलाने से बचें जब तक आप जान न लें कि यह दवा आपको कैसे प्रभावित करती है। नियमित रक्त परीक्षण करवाएं।
💊 i plus 50mg injection Uses & Benefits
[{"condition":"Iron deficiency anaemia in chronic kidney disease","description":"Used to replenish iron stores in patients with chronic kidney disease, including those on dialysis, who often have impaired iron absorption.","evidence":"Well-established"},{"condition":"Iron deficiency anaemia in pregnancy","description":"Administered when oral iron is ineffective or not tolerated, to correct maternal anaemia and support fetal development.","evidence":"Well-established"},{"condition":"Postpartum iron deficiency anaemia","description":"Used to treat significant blood loss during childbirth when oral iron is insufficient or not tolerated.","evidence":"Well-established"},{"condition":"Iron deficiency anaemia due to gastrointestinal disorders","description":"Prescribed for patients with conditions like inflammatory bowel disease or celiac disease that impair oral iron absorption.","evidence":"Well-established"},{"condition":"Preoperative iron deficiency anaemia","description":"Given before surgery to optimize haemoglobin levels and reduce the need for blood transfusions.","evidence":"Established"}]
Off-label uses: [{"condition":"Restless legs syndrome","description":"Sometimes used off-label for patients with iron deficiency and restless legs syndrome who do not respond to oral iron.","evidence":"Limited"},{"condition":"Chemotherapy-induced anaemia","description":"Occasionally used to manage anaemia in cancer patients undergoing chemotherapy, though erythropoiesis-stimulating agents are more common.","evidence":"Limited"}]
Primary treatment for: Iron deficiency anaemia
Also treats: Chronic kidney disease, Inflammatory bowel disease, Celiac disease, Heavy menstrual bleeding, Postpartum haemorrhage
📋 Drug Information
| Generic Name(s) | Iron Sucrose (50mg) |
| Brand Name | i plus 50mg injection |
| Manufacturer | Bayberry Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Haemopoetic agents |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store at room temperature (15-30°C). Do not freeze. Keep in the original container to protect from light. |
| Shelf Life | Typically 2 years from the date of manufacture, but refer to the product label for the exact expiry date. |
| WHO Guideline | The World Health Organization recommends intravenous iron for the treatment of iron deficiency anaemia in specific populations, such as pregnant women and patients with chronic kidney disease, when oral iron is not effective or tolerated. |
| ICMR Guideline | The Indian Council of Medical Research recommends intravenous iron for the management of iron deficiency anaemia in pregnancy and chronic kidney disease, following appropriate diagnosis and monitoring. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by delivering iron directly into the bloodstream, where it is taken up by the reticuloendothelial system, primarily in the liver, spleen, and bone marrow. The iron is then gradually released from the iron sucrose complex and binds to transferrin, a transport protein that carries iron to the bone marrow and other tissues. In the bone marrow, iron is incorporated into haemoglobin, the oxygen-carrying pigment of red blood cells. This process helps to replenish depleted iron stores and supports the production of healthy red blood cells, thereby correcting anaemia. The iron sucrose complex is designed to minimize the release of free iron, reducing the risk of oxidative stress and toxicity.
Mechanism Steps
💡 How to Take i plus 50mg injection
Strength: Iron Sucrose (50mg) injection
Dosage Information
| Adult Dosage | The dosage of this medicine is individualized by a qualified clinician based on the patient's iron deficit, body weight, and clinical condition. It is administered as an intravenous infusion, often in doses ranging from 100 mg to 300 mg per session, up to a maximum cumulative dose calculated from the iron deficit. The infusion rate should not exceed 20 mg iron per minute. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustments based on renal and hepatic function. Use with caution and monitor closely. |
| Renal Impairment | No specific dose adjustment is required for renal impairment, but use with caution in severe renal impairment and monitor closely. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary based on liver function. |
| Maximum Daily Dose | The maximum daily dose is determined by the patient's iron deficit and should not exceed the calculated total iron requirement. Typically, a single infusion should not exceed 300 mg of iron sucrose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of i plus 50mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Oral iron supplements | Major | |
| Dimercaprol | Major | |
| Chloramphenicol | Moderate | |
| Vitamin C | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Oral iron supplements
- Dimercaprol
⚡ Moderate Interactions
- Chloramphenicol
- Vitamin C (ascorbic acid)
🍷 Alcohol Interaction
Alcohol may increase the risk of gastrointestinal bleeding and can worsen anaemia. It is advisable to avoid alcohol while receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to iron sucrose or any component of the formulation","Iron overload or haemochromatosis","Anaemia not caused by iron deficiency","Severe liver disease","Active infections"]
⚠️ Warnings & Precautions
["Administer only in a setting with immediate access to emergency medical care.","Monitor patients for at least 30 minutes after infusion for signs of hypersensitivity.","Use with caution in patients with a history of allergies or asthma.","Avoid in patients with iron overload unless specifically indicated.","Do not use in patients with active infections.","Use with caution in elderly patients and those with renal or hepatic impairment.","Regular monitoring of iron levels is essential to prevent overload."]
🤱 Lactation Safety
Iron sucrose is excreted in breast milk in small amounts, but it is generally considered safe during breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine can lead to iron overload, which may cause nausea, vomiting, abdominal pain, and potentially serious organ damage. Treatment includes immediate discontinuation of the infusion, supportive care, and possibly chelation therapy with deferoxamine. Seek emergency medical attention if overdose is suspected.
⏰ Missed Dose
This medicine is administered by a healthcare professional, so missed doses are unlikely. If you miss a scheduled appointment for your infusion, contact your doctor to reschedule as soon as possible. Do not attempt to self-administer.
Additional Safety Advice
This medicine must only be administered by a qualified healthcare professional in a setting equipped to handle emergencies. Before receiving this medicine, inform your doctor about all your medical conditions, especially allergies, liver problems, infections, or if you are pregnant or breastfeeding. Do not receive this medicine if you have iron overload or anaemia not caused by iron deficiency. During the infusion, report any discomfort, pain, or unusual symptoms immediately. After the infusion, remain under observation for at least 30 minutes as delayed reactions can occur. Avoid driving or operating heavy machinery until you know how this medicine affects you. Keep all follow-up appointments for blood tests to monitor your response and iron levels. Do not take oral iron supplements without consulting your doctor, as this may increase the risk of iron overload. Always inform other healthcare providers that you are receiving this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, especially cardiovascular effects. Use with caution and monitor closely. Dose adjustments may be necessary based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant and have iron deficiency anaemia, consult your doctor. This medicine can be used during pregnancy if indicated, but it is important to optimize your iron levels before conception.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to treat iron deficiency anaemia resulting from blood loss. It should be administered under medical supervision, and your doctor will determine the appropriate dose and timing.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine. There are no specific contraindications for dental procedures, but your dentist may take precautions if you have anaemia.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until your haemoglobin levels improve and you feel more energetic. Light activities like walking are generally safe. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Most people can return to normal activities after the infusion, but it is best to rest for the remainder of the day.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. The decision to stop should be based on your clinical response and iron levels. If you experience serious side effects, seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to iron overload if not monitored properly. Regular blood tests to monitor ferritin and transferrin saturation levels are essential. Iron overload can cause damage to the liver, heart, and other organs. It is important to follow your doctor's instructions and attend all monitoring appointments.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
First-line treatment for iron deficiency anaemia, but may not be effective or tolerated by some patients.
Evidence: Well-establishedIncreasing dietary iron intake can help, but may not be sufficient for severe deficiency.
Evidence: EstablishedReserved for severe, life-threatening anaemia when rapid correction is needed.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, inform your healthcare provider about your vaccination status before receiving this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
This medicine is administered in a clinical setting, so travel is not typically a concern. However, if you are traveling and need to receive this medicine, ensure you carry a copy of your prescription and medical records. The medicine should be stored at room temperature and protected from light. Check with your healthcare provider about the availability of this medicine at your destination. Always inform your doctor about your travel plans.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement in haemoglobin levels is typically seen within 1 to 2 weeks after administration, but symptomatic improvement may take longer depending on the severity of anaemia.
A: This medicine is considered safe for use during pregnancy when indicated, but should be used under medical supervision. It is often used to treat iron deficiency anaemia in pregnancy when oral iron is not effective or tolerated.
A: Concurrent use of oral iron with this medicine may increase the risk of iron overload. It should only be done under the guidance of your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for i plus 50mg injection
View AllAlternative brands with exact same active ingredient:
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haemomag 50mg injectionMagma Allianz Laboratories Ltd ₹35.63 72.7% CHEAPER
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sfe 50mg injectionRavenbhel Pharmaceuticals Pvt Ltd ₹87.97 32.5% CHEAPER
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leferon 50mg injectionMac Millon Pharmaceuticals Pvt Ltd ₹96.76 25.7% CHEAPER
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uniron s 50mg injectionUnijules Life Science Ltd ₹117.19 10.1% CHEAPER
-
herfem s 50mg injectionTorrent Pharmaceuticals Ltd ₹121.88 6.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a quick fix for all types of anaemia.
Fact: This medicine is only effective for iron deficiency anaemia and should not be used for other types of anaemia. - Myth: You can self-administer this medicine at home.
Fact: This medicine must be administered by a healthcare professional in a clinical setting due to the risk of serious allergic reactions. - Myth: This medicine has no side effects.
Fact: Like all medicines, this medicine can cause side effects, ranging from mild to serious. Monitoring is essential.
🔄 Alternative Options
Generic Alternatives
- Iron sucrose injection (generic)
Brand Alternatives
- Aviron 50mg injection