allsef 1.5gm Injection (Cefuroxime 1.5g): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat or difficulty breathing after the injection
- Sudden severe rash, blistering, or peeling of the skin
- Severe, watery, or bloody diarrhoea during or after treatment
- Seizure, confusion, or unusual drowsiness
- Unusual bruising, bleeding, or a persistent sore throat with fever
- Passing very little urine or swelling of the legs and face
- Yellowing of the skin or eyes with dark urine
If experiencing severe symptoms, call emergency services immediately.
What is hoxi 1.5gm injection used for?
This medicine is a 1.5 gram injectable antibiotic containing cefuroxime. It is given by a doctor or nurse into a vein or muscle to treat moderate to severe bacterial infections such as pneumonia, urinary tract infection, skin infection, bone infection, and meningitis, and to prevent infection before some surgeries. It works by breaking down the bacterial cell wall so that the bacteria die. It is not used for viral illnesses and must be prescribed and given by a qualified clinician.
- Generic Name: Cefuroxime (1.5gm)
- Manufacturer: Stenhill Labs
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hoxi 1.5gm injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्यूरोक्सिम नामक एंटीबायोटिक का 1.5 ग्राम इंजेक्शन है, जिसे डॉक्टर या नर्स द्वारा नस या मांसपेशी में लगाया जाता है। यह निमोनिया, मूत्र मार्ग का संक्रमण, त्वचा और मांसपेशियों का संक्रमण, हड्डी और जोड़ का संक्रमण, मेनिनजाइटिस और गोनोरिया जैसे गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए दी जाती है। कुछ ऑपरेशन से पहले संक्रमण रोकने के लिए भी यह इंजेक्शन लगाया जाता है। यह वायरस से होने वाली बीमारियों जैसे सर्दी-जुकाम या फ्लू पर असर नहीं करती। यह दवा केवल डॉक्टर की सलाह और निगरानी में ही लगवानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, लालिमा या सूजन, दस्त, जी मिचलाना, उल्टी, पेट में असहजता, सिरदर्द और चक्कर आना शामिल हैं। कभी-कभी खुजली, चकत्ते, मुँह या योनि में फंगल संक्रमण और लिवर एंजाइम का अस्थायी बढ़ना देखा जाता है। गंभीर लेकिन दुर्लभ मामलों में तेज एलर्जी, त्वचा पर फफोले, गंभीर दस्त, दौरे और खून की कोशिकाओं की कमी हो सकती है। साँस लेने में कठिनाई, चेहरे या गले में सूजन हो तो तुरंत आपातकालीन मदद लें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा ही लगाई जानी चाहिए, इसे घर पर खुद न लगवाएँ। पहली खुराक से पहले अपनी सभी एलर्जी, खासकर पेनिसिलिन या सेफलोस्पोरिन से एलर्जी के बारे में डॉक्टर को बताएँ। अगर आपको किडनी या लिवर की बीमारी, दौरे की समस्या या आंतों की सूजन वाली बीमारी है तो जरूर बताएँ। आराम महसूस होने पर भी पूरा कोर्स पूरा करें, क्योंकि बीच में रोकने से संक्रमण लौट सकता है और बैक्टीरिया में प्रतिरोध बढ़ सकता है। इलाज के दौरान शराब न पिएँ। नई खुजली, चकत्ते, साँस लेने में तकलीफ, गंभीर दस्त या असामान्य नील पड़ने पर तुरंत डॉक्टर को बताएँ।
💊 hoxi 1.5gm injection Uses & Benefits
[{"condition":"Community-acquired pneumonia","description":"Used for moderate to severe bacterial pneumonia when parenteral therapy is required.","evidence":"Well-established"},{"condition":"Complicated urinary tract infection","description":"Treats kidney and bladder infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infection","description":"Used for cellulitis, wound infections, and abscesses needing injectable antibiotics.","evidence":"Well-established"},{"condition":"Bone and joint infection","description":"Given for osteomyelitis and septic arthritis as part of a longer treatment plan.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Used in hospital settings for meningitis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Gonorrhoea","description":"Used as an alternative regimen for uncomplicated gonococcal infection.","evidence":"Established"},{"condition":"Surgical prophylaxis","description":"Given before certain surgeries to reduce the risk of postoperative infection.","evidence":"Well-established"},{"condition":"Septicaemia","description":"Used in hospitalised patients with bloodstream infection caused by susceptible bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used for early disseminated Lyme disease when other options are unsuitable.","evidence":"Limited"},{"condition":"Peritonitis related to dialysis","description":"Occasionally used in selected patients with peritoneal dialysis-associated infection.","evidence":"Limited"}]
Primary treatment for: Bacterial infections caused by susceptible organisms
Also treats: Community-acquired pneumonia, Complicated urinary tract infection, Skin and soft tissue infection, Bone and joint infection, Bacterial meningitis, Gonorrhoea, Septicaemia
📋 Drug Information
| Generic Name(s) | Cefuroxime (1.5gm) |
| Brand Name | hoxi 1.5gm injection |
| Manufacturer | Stenhill Labs |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 2nd generation |
| Route of Administration | Parenteral, given by intravenous infusion over about 30 minutes or by deep intramuscular injection into a large muscle |
| Storage | Store the dry powder below 25 degrees Celsius in a dry place, protected from light. Once reconstituted, the solution should be used as directed by the pharmacist, usually within a few hours if kept at room temperature or within 24 hours if refrigerated. Do not freeze the prepared solution. |
| Shelf Life | The shelf life of the dry powder is usually 24 months from the date of manufacture when stored as directed. The prepared solution must be used within the time stated by the pharmacist. |
| WHO Guideline | Not established from the available information for this specific product. Antibiotic choice should follow local hospital or national treatment guidelines. |
| ICMR Guideline | Not established from the available information for this specific product. Prescribers should follow the current Indian Council of Medical Research antimicrobial use guidance and local resistance patterns. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a bactericidal cephalosporin antibiotic. It binds to specific penicillin-binding proteins located inside the bacterial cell wall and blocks the final step of peptidoglycan cross-linking. Without a properly cross-linked cell wall, the bacterium cannot maintain its shape or withstand internal osmotic pressure, so it bursts and dies. Because human cells do not have a peptidoglycan wall, the action is selective for bacteria.
Mechanism Steps
💡 How to Take hoxi 1.5gm injection
Strength: Sterile powder for injection containing cefuroxime 1.5 g, to be reconstituted before parenteral use.
Dosage Information
| Adult Dosage | The adult dose of this medicine is individualised by a qualified clinician based on the site and severity of infection, the likely organism, body weight, and kidney function. Typical adult schedules range from 750 mg to 1.5 g given every 6 to 8 hours by intravenous or intramuscular injection, with higher total daily doses used for severe infections such as meningitis. For surgical prophylaxis, a single dose is usually given shortly before the operation. Dose must be individualised by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific product. Doses in children are weight-based and must be calculated and prescribed by a paediatrician. Consult a paediatrician. |
| Elderly Dosage | Older adults usually receive the same dose as other adults, but kidney function declines with age and this medicine is removed by the kidneys. The clinician should check kidney function before and during treatment and reduce the dose or extend the interval if needed. |
| Renal Impairment | In kidney impairment the dose or the dosing interval must be adjusted according to the estimated glomerular filtration rate. Patients on haemodialysis need an extra dose after each dialysis session because the drug is removed by the filter. Dose must be individualised by a qualified clinician based on renal function. |
| Hepatic Impairment | Mild to moderate liver disease does not usually require a dose change because this medicine is not significantly metabolised by the liver. In severe liver disease with kidney involvement, the clinician should monitor the patient closely and adjust the dose if needed. |
| Maximum Daily Dose | The maximum daily dose is not fixed for all patients and depends on the infection and kidney function. In adults with normal kidneys, total daily doses up to about 6 g have been used for severe infections under specialist supervision. Dose must be individualised by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hoxi 1.5gm injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | |
| Furosemide | Major | |
| Warfarin | Major | |
| Chloramphenicol | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Moderate | |
| Urine glucose tests | Minor | |
| Direct Coombs test | Minor | |
| Methotrexate | Moderate |
🚨 Major Interactions
- Aminoglycoside antibiotics such as gentamicin
- Loop diuretics such as furosemide
- Warfarin
- Chloramphenicol
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
- Antacids and acid-reducing medicines
🍷 Alcohol Interaction
Alcohol does not directly change the blood level of this medicine, but it can worsen nausea, vomiting, dizziness, and dehydration while the body is fighting an infection. It is best to avoid alcohol until the course is finished and you feel fully well.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to cefuroxime or any other cephalosporin antibiotic","Previous serious immediate allergic reaction to a penicillin antibiotic","Use of the medicine for a viral illness such as the common cold or influenza","Not to be mixed in the same syringe or infusion line with aminoglycosides"]
⚠️ Warnings & Precautions
["Tell the clinical team about any allergy to penicillin or cephalosporin before the first dose.","The dose must be reduced in people with poor kidney function to avoid seizures and other toxic effects.","Prolonged use can lead to overgrowth of resistant organisms, including Candida and Clostridioides difficile.","A false-positive Coombs test and false urine sugar results can occur during treatment.","This medicine is given only by a healthcare professional and must not be self-administered.","Stop the injection and seek emergency care at the first sign of a severe allergic reaction."]
🤱 Lactation Safety
Cefuroxime passes into breast milk in small amounts. It is usually considered compatible with breastfeeding, but watch the baby for diarrhoea, thrush, or rash and speak to a doctor if these occur.
💊 Overdose Management
An overdose of this medicine can cause brain-related effects such as confusion, twitching, or seizures, especially in people with kidney disease. Treatment is supportive and includes stopping the medicine, maintaining the airway, and giving fluids. In severe cases, haemodialysis can remove cefuroxime from the blood. There is no specific antidote, so anyone with suspected overdose needs immediate hospital care.
⏰ Missed Dose
Because this medicine is given by a healthcare professional, a missed dose is managed by the clinical team. If you miss a scheduled appointment for your injection, contact the clinic or hospital as soon as possible to arrange the next dose. Do not try to catch up by taking extra doses, and do not change the schedule on your own.
Additional Safety Advice
This medicine must only be given by a doctor or nurse and never self-administered at home. Tell your doctor about every allergy you have, especially to penicillin or other cephalosporins, before the first dose. Inform the clinical team if you have kidney disease, liver disease, a seizure disorder, or inflammatory bowel disease. Complete the full course prescribed even if you feel better after a few doses, because stopping early can allow the infection to return and encourage resistance. Do not drink alcohol during treatment as it can worsen nausea and dizziness. Report any new rash, swelling, breathing difficulty, severe diarrhoea, or unusual bruising immediately. Keep all follow-up appointments so that your response to treatment and kidney function can be checked.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function, so the dose and interval of this medicine may need adjustment. They are also more prone to confusion, falls, and dehydration during infection. Monitor fluid intake, watch for dizziness, and report any new confusion or reduced urine output. Regular review of all other medicines is important to avoid interactions.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive or think you may be pregnant, tell your doctor before receiving this medicine. Cefuroxime is generally considered acceptable in pregnancy when needed for a bacterial infection, but the decision should be made by your obstetrician or treating clinician after weighing the benefits and risks. Do not delay treatment for a serious infection because of pregnancy.
🏥 Post-Surgery Considerations
This medicine is often used before, during, or after surgery to prevent or treat infection. After surgery, keep the wound clean and dry, follow your surgeon's dressing advice, and report increasing pain, redness, swelling, or discharge. Complete the full course prescribed and attend all follow-up visits so that healing and kidney function can be checked.
🦷 Dental Procedures
Tell your dentist if you are receiving this medicine or have recently finished a course. For most dental procedures, no change to your antibiotic is needed, but if you have a heart condition that requires prophylaxis, your dentist and doctor will decide the right antibiotic. Do not take leftover antibiotics for a toothache without a proper dental assessment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While you are receiving this medicine for an active infection, you should rest and avoid strenuous exercise. Gentle walking is fine once your fever has settled and you feel stronger. If you have a bone or joint infection, follow the advice of your orthopaedic team about movement and physiotherapy. Stop any activity that causes chest pain, breathlessness, or severe fatigue and tell your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
You may feel tired, dizzy, or unwell during treatment, so avoid driving or operating heavy machinery until you feel fully alert. Most people need a few days of rest, especially if they are in hospital. Office work may be possible once the fever settles, but follow your doctor's advice. If your job involves heavy physical work or exposure to infection, discuss a safe return date with your clinician.
🛑 When to Stop This Medicine
This medicine is stopped by your doctor when the infection has responded, when the course is complete, or if a serious side effect such as a severe allergic reaction occurs. Never stop the course on your own just because you feel better, because the infection may return and resistance can develop. If you develop a rash, breathing difficulty, severe diarrhoea, or any other worrying symptom, tell the clinical team immediately so that they can decide whether to stop the medicine.
📅 Long-Term Use Effects
This medicine is usually given for a short, defined course, so long-term effects are uncommon. Prolonged or repeated use can lead to antibiotic resistance, fungal overgrowth such as oral or vaginal thrush, and Clostridioides difficile diarrhoea. Rarely, blood counts and liver enzymes can change during long courses. If treatment lasts more than a few days, your doctor may check your kidney function, liver function, and blood counts, and will review whether the medicine can be stopped or switched to an oral option.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Once you are stable and able to take tablets, your doctor may switch you to an oral antibiotic to complete treatment.
Evidence: Well-establishedDepending on the organism and your allergy history, a different antibiotic such as ceftriaxone or amoxicillin-clavulanate may be chosen.
Evidence: Well-establishedRest, fluids, fever control, and good nutrition support recovery alongside antibiotics.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and routine vaccines. If you are due for a vaccine, tell the nurse that you are receiving this antibiotic. Live vaccines are generally avoided during severe illness, but this is a decision for your doctor. Antibiotics do not replace vaccination, and keeping your routine immunisations up to date helps prevent some bacterial infections.
📦 Storage Guide
✅ DO
Store the dry powder below 25 degrees Celsius in a dry place
❌ DON'T
Do not store it in a hot or damp place such as a bathroom
✅ DO
Keep the vial in its original carton, protected from light
❌ DON'T
Do not remove the label or transfer the powder to an unmarked container
✅ DO
Use the reconstituted solution within the time advised by the pharmacist
❌ DON'T
Do not freeze the prepared solution
✅ DO
Check the expiry date before use
❌ DON'T
Do not use the medicine if the powder looks discoloured or the vial is damaged
✈️ Traveling with This Medicine
This medicine is given by a healthcare professional, so travel planning should be discussed with your treating doctor. If you need treatment while travelling, carry a copy of your prescription and a letter from your doctor explaining the diagnosis, the medicine, and the dose. Keep the medicine in its original packaging with the pharmacy label visible. The dry powder should be stored below 25 degrees Celsius, away from direct sunlight and heat, and it should not be frozen. If you are flying, keep the prescription in your hand luggage and declare the medicine at security if asked. Do not carry reconstituted solution for long periods; it should be prepared and used as directed by a pharmacist. If you are crossing time zones, ask your doctor how to adjust the dosing schedule.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Bacterial killing starts within about 30 to 60 minutes of an intravenous dose, but you will usually notice improvement in fever, pain, and general wellbeing within 24 to 72 hours. Your doctor will review you during this time.
A: No. This medicine is given by a doctor or nurse in a clinic or hospital because it needs to be prepared and injected correctly and because reactions must be managed promptly.
A: Cefuroxime is generally considered acceptable in pregnancy when a bacterial infection needs treatment and the benefit outweighs the risk. Your obstetrician will decide whether it is right for you.
A: It is best to avoid alcohol during treatment because it can worsen nausea, dizziness, and dehydration while your body is fighting the infection.
A: Contact the clinic or hospital as soon as possible. Do not try to give the injection yourself and do not double the next dose.
A: Yes, it can interact with medicines such as aminoglycosides, furosemide, warfarin, and probenecid. Always give your doctor a full list of everything you take.
🤔 Common Patient Concerns
🔄 Substitutes for hoxi 1.5gm injection
View AllAlternative brands with exact same active ingredient:
-
engel 1.5gm injectionBlue Cross Laboratories Ltd ₹70.31 68.8% CHEAPER
-
bacticef s 1.5gm injectionPrayas Pharmaceuticals ₹104.64 53.5% CHEAPER
-
barcef s 1.5gm injectionOrganic Laboratories ₹110.99 50.7% CHEAPER
-
Travexel 1.5gm InjectionGold Line ₹128.91 42.7% CHEAPER
-
cefuxime 1.5gm injectionNectar Biopharma Pvt Limited ₹168.75 25% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any fever.
Fact: This medicine only works against susceptible bacteria. It does not treat viral fevers such as the common cold or influenza. - Myth: Injections always work better than tablets.
Fact: Injections are used when a person is very unwell, cannot take oral medicine, or needs high drug levels quickly. Many infections can be treated with oral antibiotics. - Myth: You can stop the injection once you feel better.
Fact: Stopping early can allow the infection to return and can encourage antibiotic resistance. Always complete the course advised by your doctor. - Myth: This medicine is safe for everyone with a penicillin allergy.
Fact: Some people with penicillin allergy can also react to cephalosporins. Always tell your doctor about any antibiotic allergy before treatment.
🔄 Alternative Options
Generic Alternatives
- Cefuroxime injection 1.5 g
Brand Alternatives
- allsef 1.5gm injection