Alocet-M Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or severe wheezing that does not improve with a rescue inhaler
- Swelling of the face, lips, tongue, or throat
- Severe skin rash with blisters or peeling
- Yellowing of the skin or eyes
- Severe abdominal pain or persistent vomiting
- Unusual mood changes, agitation, or suicidal thoughts
- Fast or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is histrin-m tablet used for?
This medicine is a combination syrup of levocetirizine and montelukast used to treat allergic rhinitis and mild asthma. It reduces sneezing, runny nose, itchy eyes, and airway inflammation. It is taken once daily as prescribed by a doctor.
- Generic Name: Levocetirizine (NA) + Montelukast (NA)
- Manufacturer: Unisarsh Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 histrin-m tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एलर्जी से होने वाली नाक की समस्या (एलर्जिक राइनाइटिस) और हल्के दमे (अस्थमा) के इलाज के लिए दी जाती है। यह छींक, नाक बहना, आंखों में खुजली और नाक बंद होने जैसे लक्षणों को कम करती है। यह सूजन और एलर्जी पैदा करने वाले पदार्थों को शरीर में काम करने से रोकती है। इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, मुंह सूखना, सिरदर्द, गले में खराश और पेट में हल्की तकलीफ शामिल हैं। कुछ मरीजों में बेचैनी, चिड़चिड़ापन या नींद में गड़बड़ी भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, या त्वचा पर गंभीर दाने दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से डोज न बढ़ाएं या कम न करें। इस दवा से नींद आ सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें। शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अगर आपको लीवर या किडनी की बीमारी है, या आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। इसे दमे के तीव्र दौरे के लिए न इस्तेमाल करें।
💊 histrin-m tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion caused by seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Mild persistent asthma","description":"Helps control airway inflammation and reduces the frequency of asthma symptoms when used with other treatments.","evidence":"Well-established"},{"condition":"Exercise-induced bronchoconstriction","description":"May reduce narrowing of airways triggered by physical activity in some patients.","evidence":"Moderate"},{"condition":"Chronic urticaria","description":"Levocetirizine component helps relieve itching and hives in some patients.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Sleep-related breathing disorders in children","description":"Sometimes prescribed off-label for mild sleep-disordered breathing associated with allergic rhinitis.","evidence":"Limited"},{"condition":"Eosinophilic bronchitis","description":"Rarely used off-label to reduce airway inflammation in selected patients.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Mild persistent asthma, Exercise-induced bronchoconstriction, Chronic urticaria
📋 Drug Information
| Generic Name(s) | Levocetirizine (NA) + Montelukast (NA) |
| Brand Name | histrin-m tablet |
| Manufacturer | Unisarsh Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from direct sunlight and moisture. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Levocetirizine selectively blocks histamine H1 receptors, preventing histamine from causing sneezing, itching, runny nose, and watery eyes. Montelukast selectively blocks cysteinyl leukotriene receptors, reducing leukotriene-mediated airway inflammation, mucus secretion, and bronchoconstriction. Together, they address both immediate allergic symptoms and underlying airway inflammation.
Mechanism Steps
💡 How to Take histrin-m tablet
Strength: Each 5 mL of syrup contains levocetirizine 2.5 mg and montelukast 4 mg, or as specified on the product label.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 mL to 10 mL of syrup once daily, preferably in the evening, or as directed by your doctor. The exact dose depends on the indication, severity of symptoms, and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the drowsiness caused by this medicine. Your doctor may start with a lower dose and monitor you closely. Dose must be individualized by a qualified clinician based on kidney and liver function. |
| Renal Impairment | Levocetirizine dose may need to be reduced in patients with kidney disease. Consult your doctor for dose adjustment based on your kidney function. |
| Hepatic Impairment | No specific dose adjustment is established for mild to moderate liver disease. In severe liver disease, use with caution and only under specialist supervision. |
| Maximum Daily Dose | The maximum daily dose should not exceed the dose prescribed by your doctor. Do not take more than 10 mL of this syrup in 24 hours unless specifically instructed by your clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of histrin-m tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| CNS depressants | Major | |
| Strong CYP3A4 inducers | Major | |
| Sedating antihistamines | Moderate | |
| Gemfibrozil | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- CNS depressants (e.g., benzodiazepines, opioids, alcohol)
- Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)
⚡ Moderate Interactions
- Sedating antihistamines (e.g., diphenhydramine, hydroxyzine)
- Gemfibrozil
🍷 Alcohol Interaction
Alcohol can increase drowsiness and dizziness caused by this medicine. It is best to avoid alcohol while taking this medicine, especially before driving or operating machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to levocetirizine, montelukast, or any component of this medicine","Severe liver disease without specialist supervision","Children below the age recommended by the prescribing clinician"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness. Avoid driving or operating heavy machinery until you know how it affects you.","Do not use this medicine to treat an acute asthma attack. Always keep a rescue inhaler available if prescribed.","Neuropsychiatric events have been reported with montelukast. Contact your doctor if you notice mood or behavior changes.","Inform your doctor if you have liver or kidney disease.","Do not share this medicine with others, even if they have similar symptoms.","Keep out of reach of children."]
🤱 Lactation Safety
Levocetirizine and montelukast may pass into breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
If you suspect an overdose, contact your doctor or visit the nearest emergency department immediately. Symptoms of overdose may include severe drowsiness, restlessness, or stomach upset. Do not try to induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose on your own. This medicine may cause drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. Inform your doctor if you have liver or kidney problems, or if you are pregnant, planning pregnancy, or breastfeeding. Do not use this medicine for an acute asthma attack; it is not a rescue inhaler. Keep all follow-up appointments so your doctor can monitor your response and adjust treatment if needed. Store this medicine in its original container, away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to drowsiness and dizziness. Use with caution and monitor kidney function.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy while taking this medicine. The safety of this combination in pregnancy is not well established.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medicines used during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth, which can affect dental health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise may trigger asthma symptoms in some patients. Use your rescue inhaler as prescribed before exercise if advised by your doctor. Avoid exercising in cold, dry air or high pollen environments.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also affect concentration, so take precautions at work.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately. Your doctor will decide whether to stop or change the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may require periodic monitoring of liver function and kidney function. Montelukast has been associated with rare neuropsychiatric events, so mood and behavior should be monitored. Do not use for longer than prescribed without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing exposure to allergens can help control symptoms.
Evidence: Well-establishedCan help relieve nasal congestion.
Evidence: ModerateAllergy shots may provide long-term relief for some patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interfere with vaccines. However, consult your doctor about the timing of vaccinations if you are unwell.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If you are traveling across time zones, take your dose at the usual time in your new time zone. Check customs regulations for carrying prescription medicines. Keep enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Levocetirizine starts relieving allergy symptoms within 1 hour, while montelukast may take several days to show full benefit for asthma.
A: Yes, taking it in the evening is often recommended to reduce daytime drowsiness.
A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.
A: Do not stop this medicine without consulting your doctor, especially if you are taking it for asthma.
🤔 Common Patient Concerns
🔄 Substitutes for histrin-m tablet
View AllAlternative brands with exact same active ingredient:
-
rem cc lm syrupKarnataka Antibiotics & Pharmaceuticals Ltd ₹32.81 61.1% CHEAPER
-
montello syrupAbaris Healthcare ₹40.89 51.5% CHEAPER
-
ibikast l kid syrupIndiabulls pharmaceutical ltd ₹43.13 48.9% CHEAPER
-
nulify tablet dtGold Line ₹46.88 44.4% CHEAPER
-
lemoleb syrupLeben Life Sciences Pvt Ltd ₹54.45 35.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any cough and cold.
Fact: This medicine is specifically for allergic conditions and asthma. It is not a general cough and cold remedy. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine is a prescription product and should only be taken under medical supervision. - Myth: This medicine can replace a rescue inhaler during an asthma attack.
Fact: This medicine is not a rescue inhaler and should not be used to treat an acute asthma attack.
🔄 Alternative Options
Generic Alternatives
- Levocetirizine + Montelukast syrup
Brand Alternatives
- Alocet-M Syrup