Eurepa 2 Tablet (Repaglinide 2 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Confusion, seizures, or loss of consciousness
- Severe shakiness, sweating, or palpitations that do not improve after eating sugar
- Rash, swelling of the face or throat, or difficulty breathing
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain
- Unusual bruising or bleeding
- Persistent vomiting or inability to eat
- Blood sugar readings that are very high or very low despite following the prescription
If experiencing severe symptoms, call emergency services immediately.
What is hirepa 2mg tablet used for?
This medicine contains Repaglinide 2 mg, an oral antidiabetic tablet used to control blood sugar in adults with type 2 diabetes. It is taken 15 to 30 minutes before each main meal to lower post-meal blood sugar spikes. It can cause low blood sugar, so meals should not be skipped.
- Generic Name: Repaglinide (2mg)
- Manufacturer: Healing Pharma India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hirepa 2mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज वाले वयस्कों में ब्लड शुगर को कंट्रोल करने के लिए इस्तेमाल की जाती है। इसमें रेपाग्लिनाइड 2 मिलीग्राम होता है, जो खाने के बाद ब्लड शुगर बढ़ने को कम करता है। इसे आमतौर पर हर मुख्य भोजन से 15 से 30 मिनट पहले लिया जाता है। यह दवा शरीर में इंसुलिन बनने में मदद करती है। इसे डॉक्टर की सलाह के बिना शुरू या बंद न करें।
साइड इफेक्ट्स: इस दवा के आम साइड इफेक्ट्स में लो ब्लड शुगर (हाइपोग्लाइसीमिया), वजन बढ़ना, सिरदर्द, जी मिचलाना और जुकाम जैसे लक्षण शामिल हैं। अगर आप खाना स्किप करते हैं या शराब पीते हैं तो लो ब्लड शुगर का खतरा बढ़ जाता है। लो ब्लड शुगर के लक्षण जैसे कंपकंपी, पसीना, चक्कर आना और कमजोरी महसूस होने पर तुरंत मीठा खाएं और डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर हर मुख्य भोजन से 15 से 30 मिनट पहले। अगर आप कोई भोजन नहीं कर रहे हैं तो उस समय की दवा न लें। लो ब्लड शुगर से बचने के लिए हमेशा ग्लूकोज या मीठी चीज साथ रखें। शराब न पिएं। अपनी ब्लड शुगर नियमित रूप से जांचें। अन्य दवाओं के बारे में डॉक्टर को बताएं। बिना सलाह दवा बंद या शुरू न करें।
💊 hirepa 2mg tablet Uses & Benefits
- [{"condition":"Type 2 diabetes mellitus","description":"This medicine is used to improve blood sugar control in adults with type 2 diabetes when diet and exercise alone are not enough.
- It lowers post-meal blood sugar spikes by increasing insulin release from the pancreas.","evidence":"Well-established"},{"condition":"Type 2 diabetes with metformin","description":"This medicine may be combined with metformin when a single medicine does not achieve target blood sugar levels.
- The combination targets both fasting and post-meal glucose.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gestational diabetes","description":"Sometimes considered off-label in pregnancy when insulin is not suitable, but safety data are limited and specialist supervision is required.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Obesity, Dyslipidemia, Hypertension
📋 Drug Information
| Generic Name(s) | Repaglinide (2mg) |
| Brand Name | hirepa 2mg tablet |
| Manufacturer | Healing Pharma India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Meglitinides (Insulin Secretogogues) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a meglitinide that closes ATP-sensitive potassium channels in the membrane of pancreatic beta cells. This closure causes depolarization of the beta cell membrane, which opens voltage-gated calcium channels. The resulting calcium influx triggers the release of insulin from stored granules. Because the drug binds to a site distinct from sulfonylureas and has a rapid onset and short duration, it mainly enhances insulin secretion during meals, helping to reduce post-meal blood sugar spikes.
Mechanism Steps
💡 How to Take hirepa 2mg tablet
Strength: Repaglinide 2 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine is 0.5 mg to 2 mg taken orally within 15 to 30 minutes before each main meal, depending on blood sugar levels and other medicines. The dose may be adjusted by your doctor based on your response. The maximum recommended single dose is 4 mg with meals, and the total daily dose should not exceed 16 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and other medicines being taken. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood sugar-lowering effects of this medicine. Start with a lower dose and monitor blood sugar closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney impairment. The dose may need to be reduced, and blood sugar should be monitored closely. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | This medicine is not recommended in patients with severe liver disease. In mild to moderate liver impairment, use with caution and monitor blood sugar and liver function. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | 16 mg per day, divided with meals. Individual doses should not exceed 4 mg per meal. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hirepa 2mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gemfibrozil | Major | |
| Clopidogrel | Major | |
| Insulin | Major | |
| Sulfonylureas | Major | |
| Ketoconazole | Moderate | |
| Clarithromycin | Moderate | |
| Rifampicin | Moderate | |
| Carbamazepine | Moderate | |
| Beta-blockers | Moderate | |
| NSAIDs | Minor |
🚨 Major Interactions
- Gemfibrozil
- Clopidogrel
- Other antidiabetic medicines (insulin, sulfonylureas, metformin)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
- Beta-blockers
🍷 Alcohol Interaction
Alcohol can increase the risk of hypoglycemia when taken with this medicine. It may also cause flushing, nausea, and rapid heartbeat. It is best to avoid alcohol or limit it strictly and only with your doctor's approval.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to Repaglinide or any component of the tablet","Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe liver disease","Concurrent use of gemfibrozil","Pregnancy and breastfeeding unless specifically advised by a specialist"]
⚠️ Warnings & Precautions
["This medicine can cause hypoglycemia, especially if meals are skipped or delayed.","Always take this medicine before meals as prescribed.","Avoid alcohol while taking this medicine.","Tell your doctor about all other medicines you take, especially gemfibrozil and clopidogrel.","Use with caution in elderly patients and those with kidney or liver problems.","Do not drive or operate machinery if you experience symptoms of low blood sugar.","This medicine is not for type 1 diabetes or diabetic ketoacidosis.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
It is not known whether Repaglinide passes into breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor.
💊 Overdose Management
Overdose of this medicine can cause severe hypoglycemia. Symptoms include confusion, seizures, and loss of consciousness. If overdose is suspected, seek emergency medical care immediately. Treatment may include oral glucose if the patient is conscious, or intravenous glucose and close monitoring in a hospital setting.
⏰ Missed Dose
If you miss a dose before a meal, take it as soon as you remember if you are still going to eat that meal. If you have already eaten or if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed, usually within 15 to 30 minutes before each main meal. Do not take it if you are skipping a meal, because the risk of low blood sugar increases. Always carry a source of fast-acting sugar such as glucose tablets, candy, or fruit juice to treat hypoglycemia. Check your blood sugar regularly as advised by your doctor. Avoid alcohol because it can cause unpredictable drops in blood sugar. Tell your doctor about all other medicines, especially gemfibrozil, clopidogrel, and blood pressure medicines. Do not drive or operate heavy machinery if you feel dizzy or shaky from low blood sugar. Keep all follow-up appointments for blood sugar, kidney, and liver monitoring. Do not start, stop, or change the dose without consulting your clinician.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood sugar-lowering effects of this medicine and may have a higher risk of hypoglycemia. Start with a lower dose and monitor blood sugar closely. Also consider kidney and liver function, which may decline with age. Dose must be individualized by a qualified clinician.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. This medicine is not recommended during pregnancy unless specifically advised by a specialist. Your doctor may switch you to insulin or another suitable treatment. Good blood sugar control before and during pregnancy is important for both mother and baby.
🏥 Post-Surgery Considerations
After surgery, blood sugar levels can be unstable. Inform your surgeon and anesthesiologist that you take this medicine. Your doctor may adjust the dose or temporarily switch to insulin. Do not take this medicine without medical advice if you are not eating normally after surgery.
🦷 Dental Procedures
Inform your dentist that you take this medicine. If a dental procedure requires you to skip a meal, skip the dose for that meal to avoid low blood sugar. Check your blood sugar before and after the procedure, and carry fast-acting sugar.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is good for diabetes control, but it can lower blood sugar. Check your blood sugar before and after exercise, and carry fast-acting sugar. Avoid intense exercise if your blood sugar is low or if you feel unwell. Consult your doctor before starting a new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause low blood sugar, which may affect your ability to drive or operate machinery. Do not drive if you feel shaky, dizzy, or confused. Inform your employer about your diabetes and the medicine you take if your job involves safety-sensitive tasks. With proper meal timing and monitoring, most people can continue their normal daily activities.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. If you experience severe side effects, persistent low blood sugar, or other health changes, contact your doctor. Your doctor may adjust the dose, switch to another medicine, or stop it based on your condition. Always follow medical advice before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to weight gain and repeated episodes of low blood sugar if meals are irregular. It does not cure diabetes, so it must be continued along with diet, exercise, and regular monitoring. Periodic checks of blood sugar, HbA1c, kidney function, and liver function are important. Your doctor may adjust or change the medicine over time based on your diabetes control and overall health.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A personalized diet plan can help control blood sugar and may reduce the need for higher doses of medicine.
Evidence: Well-establishedExercise improves insulin sensitivity and helps control blood sugar along with medicine.
Evidence: Well-establishedMetformin, sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors, or insulin may be considered based on your condition.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
People with diabetes should stay up to date with recommended vaccines, including influenza and pneumococcal vaccines, as advised by their doctor. There is no specific interaction between this medicine and vaccines, but blood sugar should be monitored around the time of vaccination, especially if you feel unwell.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage so it stays at room temperature and is not exposed to extreme heat or cold. If you are traveling across time zones, discuss with your doctor how to adjust the timing of doses around meals. Carry fast-acting sugar and a glucose meter if possible. Check customs rules for carrying prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 15 to 30 minutes after you take it and its effect lasts about 4 to 6 hours, covering the post-meal period.
A: No. You should skip the dose if you are not eating that meal, because taking it without food increases the risk of low blood sugar.
A: Yes, it is often combined with metformin when a single medicine does not control blood sugar well. Your doctor will adjust the doses and monitor your blood sugar.
A: These are signs of low blood sugar. Check your blood sugar if possible and eat or drink something sweet immediately. If symptoms do not improve, seek medical help.
A: Safety in pregnancy is not well established. It should be used only if clearly needed and under specialist supervision.
🤔 Common Patient Concerns
🔄 Substitutes for hirepa 2mg tablet
View AllAlternative brands with exact same active ingredient:
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regan 2mg tabletSun Pharmaceutical Industries Ltd ₹75.01 67.4% CHEAPER
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rapilin 2mg tabletSun Pharmaceutical Industries Ltd ₹84.36 63.3% CHEAPER
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Repomine 2mg TabletShinto Organics (P) Limited ₹132.19 42.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps control blood sugar but does not cure diabetes. It must be continued along with diet, exercise, and regular monitoring. - Myth: I can skip meals if I take this medicine.
Fact: Skipping meals while taking this medicine increases the risk of low blood sugar. Always take it before a meal. - Myth: This medicine is the same as insulin.
Fact: This medicine is an oral tablet that stimulates the pancreas to release insulin. It is not insulin itself.
🔄 Alternative Options
Generic Alternatives
- Repaglinide 2 mg tablet
Brand Alternatives
- Eurepa 2 Tablet