Acrub Gel: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
- Severe skin rash or blistering
- Signs of systemic NSAID effects (black stools, vomiting blood, severe abdominal pain)
- Decreased urine output or swelling in legs
- Chest pain or shortness of breath
- Yellowing of skin or eyes (jaundice)
If experiencing severe symptoms, call emergency services immediately.
What is hifenac gel used for?
This medicine is a topical gel containing aceclofenac 1.5% w/w, an NSAID used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and soft tissue injuries. It works by inhibiting COX enzymes and reducing prostaglandins. Apply a thin layer to the affected area 2-3 times daily, or as directed by your doctor.
- Generic Name: Aceclofenac (1.5% w/w)
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hifenac gel के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटोक्लोफेनाक 1.5% w/w जेल है, जिसका उपयोग जोड़ों के दर्द, सूजन और मांसपेशियों की समस्याओं जैसे ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस, और मोच में आराम के लिए किया जाता है। यह जेल त्वचा पर लगाने से प्रभावित हिस्से में दर्द और सूजन कम करती है। इसे दिन में 2-3 बार पतली परत में लगाएं या डॉक्टर के निर्देशानुसार।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में त्वचा पर जलन, लालिमा, खुजली या हल्की जलन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर गंभीर रैश हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल त्वचा पर लगाएं, आंखों, म्यूकस मेम्ब्रेन या खुले घावों पर न लगाएं। लगाने के बाद हाथ धो लें, जब तक कि हाथ ही इलाज वाला हिस्सा न हो। इलाज वाले हिस्से को पट्टी या गर्म पैड से न ढकें। धूप में जाने से बचें क्योंकि इससे त्वचा में जलन हो सकती है। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 hifenac gel Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis when applied topically over the affected joint.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Provides local symptomatic relief of pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling in joints affected by rheumatoid arthritis, as an adjunct to systemic therapy.","evidence":"Moderate"},{"condition":"Ankylosing spondylitis","description":"Helps reduce pain and stiffness in the spine and sacroiliac joints when applied over the affected areas.","evidence":"Limited"},{"condition":"Soft tissue injuries","description":"Used for symptomatic relief of pain and inflammation in sprains, strains, and sports injuries.","evidence":"Moderate"},{"condition":"Localized musculoskeletal pain","description":"Provides targeted relief for conditions such as tendinitis, bursitis, and low back pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for prevention of migraines, but evidence is limited and not recommended as first-line.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"Topical application over the lower abdomen may be used off-label for menstrual pain, but oral NSAIDs are preferred.","evidence":"Limited"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Soft tissue injuries, Localized musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Aceclofenac (1.5% w/w) |
| Brand Name | hifenac gel |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the tube tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the cyclooxygenase (COX) enzymes, primarily COX-2, which are responsible for converting arachidonic acid into prostaglandins. Prostaglandins are mediators of pain, inflammation, and fever. By blocking their production in the applied area, aceclofenac reduces local pain and swelling. Aceclofenac also inhibits the release of lysosomal enzymes and may affect other inflammatory mediators, contributing to its anti-inflammatory and analgesic effects. When applied topically, it penetrates the skin and reaches the underlying inflamed tissues, providing localized relief with minimal systemic absorption.
Mechanism Steps
💡 How to Take hifenac gel
Strength: Aceclofenac 1.5% w/w gel
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area 2 to 3 times daily, or as directed by your doctor. The dose and frequency may vary depending on the condition being treated and your response to therapy. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to the side effects of NSAIDs. Use with caution and follow the doctor's advice. No specific dose adjustment is required for topical use, but prolonged use should be monitored. |
| Renal Impairment | No dose adjustment is required for topical aceclofenac in mild to moderate renal impairment. However, use with caution in severe renal impairment and consult a doctor. |
| Hepatic Impairment | No dose adjustment is required for topical aceclofenac in mild to moderate hepatic impairment. Use with caution in severe hepatic impairment and consult a doctor. |
| Maximum Daily Dose | The maximum recommended daily dose for topical aceclofenac is not established from available information. Follow your doctor's prescription. Do not exceed the recommended application frequency. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hifenac gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| Lithium | Moderate | |
| Aspirin | Moderate | |
| Clopidogrel | Moderate | |
| Topical corticosteroids | Minor |
🚨 Major Interactions
- Oral NSAIDs (e.g., ibuprofen, naproxen)
- Anticoagulants (e.g., warfarin)
- Methotrexate
⚡ Moderate Interactions
- Antihypertensives (e.g., ACE inhibitors, diuretics)
- Corticosteroids
- Lithium
🍷 Alcohol Interaction
No specific interaction between alcohol and topical aceclofenac has been established. However, alcohol may increase the risk of gastrointestinal bleeding if aceclofenac is absorbed systemically. It is advisable to limit alcohol consumption while using this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to aceclofenac or any component of the gel","History of asthma, urticaria, or allergic reactions after taking aspirin or other NSAIDs","Application to broken, infected, or inflamed skin","Use in children under 14 years (unless prescribed)","Third trimester of pregnancy","Severe renal or hepatic impairment"]
⚠️ Warnings & Precautions
["For external use only. Do not ingest.","Avoid contact with eyes, mucous membranes, and open wounds.","Do not apply to large areas of skin or use for prolonged periods without medical advice.","Avoid sun exposure to treated areas due to risk of photosensitivity.","Wash hands after application unless hands are the treated area.","Do not use airtight dressings over the treated area.","Consult a doctor if symptoms persist or worsen after 7 days.","Use with caution in elderly patients and those with renal or hepatic impairment.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether aceclofenac is excreted in human milk after topical application. However, systemic absorption is low. Consult a doctor before using this medicine while breastfeeding. Avoid applying to the breast area to prevent infant exposure.
💊 Overdose Management
Overdose with topical aceclofenac is unlikely due to low systemic absorption. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, abdominal pain, and drowsiness. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
For safe use of this medicine, apply it only to intact skin and avoid contact with eyes, mucous membranes, or open wounds. Wash your hands thoroughly after application unless the hands are the treated area. Do not cover the treated area with airtight dressings or heat pads, as this may increase absorption and the risk of side effects. Avoid sun exposure to treated skin, as aceclofenac can cause photosensitivity. Do not use this medicine for more than the recommended duration without medical advice. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not use it on children under 14 years of age unless prescribed by a doctor. If symptoms persist or worsen after 7 days of use, stop and consult a healthcare professional.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of NSAIDs, including skin reactions and systemic effects if absorbed. Use with caution and follow the doctor's advice. Regular monitoring of renal and hepatic function may be advisable if used long-term.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. Topical aceclofenac should be used during pregnancy only if clearly needed. Avoid use in the third trimester due to potential risk of premature closure of the ductus arteriosus.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your surgeon. It may help with post-operative pain and inflammation, but ensure the surgical wound is fully closed before applying. Avoid applying to broken skin or incisions.
🦷 Dental Procedures
This medicine is not typically used for dental pain. If you have dental procedures, inform your dentist about all medications you are using. For dental pain, consult your dentist for appropriate treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While using this medicine, you can continue with your regular exercise routine as tolerated. However, avoid strenuous activities that may worsen your condition. If you experience increased pain or swelling, rest the affected area and consult your doctor. Low-impact exercises like walking, swimming, and stretching are generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness (rare), avoid these activities. You can continue your normal work routine, but take breaks to rest the affected area if needed.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your symptoms do not improve after 7 days, if they worsen, or if you experience any severe side effects such as skin rash, allergic reactions, or signs of systemic NSAID effects. Do not stop prescribed treatment without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is generally not recommended without medical supervision. Prolonged application over large areas may increase systemic absorption and the risk of NSAID-related side effects such as gastrointestinal, renal, or cardiovascular issues. Regular monitoring by a doctor is advised if long-term use is necessary. Skin reactions may also occur with prolonged use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and inflammation.
Evidence: ModerateMay provide pain relief for some individuals with musculoskeletal pain.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine. However, consult your doctor if you have any concerns.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription to avoid issues at customs. Store it in a cool, dry place away from direct sunlight. If traveling to a hot climate, keep it in a cool bag. There are no specific time zone adjustments needed for topical application, but maintain your regular schedule as much as possible.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 30 to 60 minutes after application. However, the full anti-inflammatory effect may take a few days of regular use.
A: This medicine is not recommended for use on the face unless specifically prescribed by a doctor. Avoid contact with eyes and mucous membranes.
A: This medicine is not recommended for children under 14 years of age unless prescribed by a doctor. Consult a pediatrician for appropriate pain relief options.
A: Using this medicine with oral NSAIDs may increase the risk of side effects. Consult your doctor before combining them.
A: If you develop a rash or severe skin irritation, stop using this medicine and consult a doctor. Mild irritation may resolve on its own, but persistent symptoms need medical attention.
🤔 Common Patient Concerns
🔄 Substitutes for hifenac gel
View AllAlternative brands with exact same active ingredient:
-
starnac gelInvision Medi Sciences Pvt Ltd ₹45.45 57.8% CHEAPER
-
gag pr gelMoraceae Pharmaceuticals Pvt Ltd ₹50.00 53.6% CHEAPER
-
Naid GelWinsome Laboratories Pvt Ltd ₹50.38 53.3% CHEAPER
-
nusaid 1.5% gelMolekule India Pvt Ltd ₹66.96 37.9% CHEAPER
-
acrub gelPsychotropics India Ltd ₹82.00 23.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any type of pain.
Fact: This medicine is specifically for localized musculoskeletal pain and inflammation. It is not effective for headaches, fever, or internal pain. - Myth: More gel means faster relief.
Fact: Applying more than the recommended amount does not speed up relief and may increase the risk of side effects. Use a thin layer as directed. - Myth: This medicine is completely safe because it is topical.
Fact: While topical NSAIDs have fewer systemic side effects, they can still cause skin reactions and, rarely, systemic effects if used excessively.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 1.5% w/w gel
Brand Alternatives
- Acrub Gel
- Aceclo Gel
- Hifenac Gel
- Zerodol Gel
- Aceproxyvon Gel