Fycompa 6mg Tablet (Perampanel): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- New or worsening aggression, hostility, or anger
- Thoughts of self-harm or suicide
- Severe dizziness or fainting
- Falls or difficulty with balance
- Rash, blisters, or peeling skin
- Yellowing of the skin or eyes, dark urine, or abdominal pain
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Seizures that become more frequent or severe
If experiencing severe symptoms, call emergency services immediately.
What is hetram 6mg tablet used for?
This medicine is a prescription anticonvulsant used as add-on therapy for partial-onset seizures and primary generalized tonic-clonic seizures in patients 12 years and older. It works by blocking AMPA receptors in the brain to reduce seizure activity.
- Generic Name: Perampanel (6mg)
- Manufacturer: Hetero Healthcare Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hetram 6mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पेराम्पैनेल नामक सक्रिय तत्व से बनी है और यह मिर्गी (एपिलेप्सी) के इलाज में उपयोग की जाती है। यह आंशिक दौरे (पार्शियल सीज़र्स) और प्राइमरी जनरलाइज़्ड टॉनिक-क्लोनिक दौरे के लिए अन्य दवाओं के साथ मिलाकर दी जाती है। यह दवा 12 वर्ष और उससे अधिक उम्र के मरीज़ों के लिए है। यह मस्तिष्क में ग्लूटामेट नामक रसायन के प्रभाव को रोककर दौरों को कम करती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, नींद आना, थकान, चिड़चिड़ापन, मतली, सिरदर्द और चलने में परेशानी शामिल हैं। ये प्रभाव आमतौर पर दवा शुरू करने या खुराक बढ़ाने पर अधिक होते हैं और धीरे-धीरे कम हो जाते हैं। गंभीर दुष्प्रभावों में आक्रामकता, शत्रुता, आत्महत्या के विचार, गंभीर चक्कर आना और गिरना शामिल हैं। यदि आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेते समय वाहन चलाने या मशीनरी चलाने से बचें क्योंकि यह नींद और चक्कर ला सकती है। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। इस दवा को अचानक बंद न करें, इससे दौरे फिर से शुरू हो सकते हैं। दवा को डॉक्टर के बताए अनुसार ही लें। यदि आपको मूड में बदलाव, आक्रामकता या आत्महत्या के विचार आएं तो तुरंत डॉक्टर को बताएं।
💊 hetram 6mg tablet Uses & Benefits
[{"condition":"Partial-onset seizures with or without secondary generalization","description":"Used as adjunctive therapy in patients 12 years and older with epilepsy who have not achieved adequate seizure control with other antiepileptic drugs.","evidence":"Well-established"},{"condition":"Primary generalized tonic-clonic seizures","description":"Used as adjunctive therapy in patients 12 years and older with idiopathic generalized epilepsy.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Refractory status epilepticus","description":"Sometimes used off-label in hospital settings for refractory status epilepticus, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Epilepsy
Also treats: Partial-onset seizures, Primary generalized tonic-clonic seizures
📋 Drug Information
| Generic Name(s) | Perampanel (6mg) |
| Brand Name | hetram 6mg tablet |
| Manufacturer | Hetero Healthcare Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | AMPA glutamate receptor antagonist |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep in a dry place away from moisture and heat. Keep out of reach of children. |
| Shelf Life | Not established from the available information. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a selective non-competitive antagonist of the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) subtype of glutamate receptors in the brain. By blocking these receptors, it reduces the excitatory neurotransmission that contributes to seizure generation and spread. This action helps stabilize neuronal activity and decrease the frequency of seizures.
Mechanism Steps
💡 How to Take hetram 6mg tablet
Strength: This medicine is available as a 6 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults and adolescents 12 years and older is 2 mg once daily at bedtime. The dose may be increased by 2 mg increments no more frequently than every 2 weeks, based on clinical response and tolerability, up to a maximum of 12 mg once daily. For patients taking enzyme-inducing antiepileptic drugs, the starting dose may be 4 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, drowsiness, and falls. Dose should be titrated slowly and carefully. No specific dose adjustment is recommended based solely on age, but individualization is necessary. |
| Renal Impairment | No dose adjustment is required for patients with mild to moderate renal impairment. This medicine should be used with caution in patients with severe renal impairment. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | For patients with mild or moderate hepatic impairment, the dose should be titrated slowly and carefully. The maximum recommended dose is 6 mg once daily for patients with mild or moderate hepatic impairment. This medicine is contraindicated in patients with severe hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 12 mg once daily for patients without hepatic impairment and not taking enzyme-inducing antiepileptic drugs. For patients with mild or moderate hepatic impairment, the maximum dose is 6 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hetram 6mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Carbamazepine | Major | |
| Phenytoin | Major | |
| Rifampin | Major | |
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Alcohol | Major | |
| Oral contraceptives | Moderate | |
| Valproate | Moderate | |
| Lamotrigine | Moderate | |
| Benzodiazepines | Moderate |
🚨 Major Interactions
- Strong CYP3A4 inducers (e.g., carbamazepine, phenytoin, rifampin)
- Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- Alcohol
⚡ Moderate Interactions
- Oral contraceptives
- Other antiepileptic drugs (e.g., valproate, lamotrigine)
- Sedatives and hypnotics (e.g., benzodiazepines, zolpidem)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase the central nervous system depressant effects, leading to increased drowsiness, dizziness, and impaired coordination. This can increase the risk of falls and accidents.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to perampanel or any component of the formulation","Severe hepatic impairment","Severe renal impairment"]
⚠️ Warnings & Precautions
["This medicine can cause serious psychiatric side effects, including aggression, hostility, and suicidal thoughts. Monitor patients closely for mood changes.","This medicine can cause dizziness, drowsiness, and gait disturbances. Patients should not drive or operate machinery until they know how it affects them.","This medicine should not be stopped abruptly because this can cause withdrawal seizures. Taper gradually under medical supervision.","This medicine may increase the risk of falls, especially in elderly patients.","This medicine may decrease the effectiveness of oral contraceptives. Women should use additional non-hormonal contraception.","This medicine should be used with caution in patients with liver or kidney impairment.","This medicine may cause severe skin reactions. Discontinue and seek medical attention if a rash develops."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human breast milk. Because many drugs are excreted in human milk, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Consult your doctor before breastfeeding.
💊 Overdose Management
There is limited experience with overdose of this medicine. In case of overdose, immediate medical attention is required. Treatment should be symptomatic and supportive. Gastric lavage may be considered if the overdose is recent. There is no specific antidote. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
This medicine can cause significant drowsiness and dizziness, so do not drive or operate machinery until you know how it affects you. Avoid alcohol because it can increase drowsiness and dizziness. Do not stop taking this medicine suddenly, as this can cause withdrawal seizures. Always take this medicine exactly as prescribed by your doctor. Inform your doctor about all other medicines you are taking, especially those that affect liver enzymes. If you experience mood changes, aggression, or thoughts of self-harm, contact your doctor immediately. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, particularly dizziness, drowsiness, and falls. Dose should be titrated slowly and carefully. Regular monitoring for balance and cognitive function is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before conception. This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Effective contraception is recommended for women of childbearing potential. Your doctor may adjust the dose or switch to another medicine.
🏥 Post-Surgery Considerations
After surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and increase the risk of central nervous system depression. Your doctor may need to adjust the dose or monitor you closely.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with sedatives or anesthetics used during dental work. Your dentist may need to take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness and drowsiness, which may affect your balance and coordination. Avoid activities that require alertness, such as swimming alone, cycling, or operating heavy machinery, until you know how the medicine affects you. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and difficulty concentrating, which may affect your ability to work, especially if your job requires alertness or operating machinery. Discuss with your employer about any necessary accommodations. Avoid driving until you know how the medicine affects you.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Abrupt discontinuation can cause withdrawal seizures. Your doctor will gradually taper the dose if it needs to be stopped. If you experience serious side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with continued seizure control, but it requires regular monitoring for side effects such as mood changes, dizziness, and gait disturbances. Liver and kidney function should be monitored periodically. Do not stop the medicine without consulting your doctor, as abrupt withdrawal can cause seizures.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A high-fat, low-carbohydrate diet that may help reduce seizures in some patients with epilepsy, especially children.
Evidence: Well-established for certain types of epilepsyA device implanted under the skin that sends electrical impulses to the vagus nerve to reduce seizures.
Evidence: Well-established for refractory epilepsySurgical removal of the brain area causing seizures, considered for some patients with refractory epilepsy.
Evidence: Well-established for selected patients💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine, especially live vaccines, while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, consult your doctor about adjusting the dosing schedule. Store at room temperature and avoid extreme heat or cold. Check customs regulations for controlled substances before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take several weeks to reach its full effect. Dose is usually increased gradually over 2 to 4 weeks. You may notice a reduction in seizure frequency within the first few weeks, but it may take longer for some patients.
A: Yes, this medicine is often used as add-on therapy with other antiepileptic drugs. However, some drugs can affect its levels, so your doctor may need to adjust the dose.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be avoided because it can increase drowsiness, dizziness, and impair coordination, increasing the risk of falls and accidents.
A: There are limited data on its use in pregnancy. It should be used only if the potential benefit justifies the potential risk to the fetus. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for hetram 6mg tablet
View AllAlternative brands with exact same active ingredient:
-
ampanel 6 tabletSun Pharmaceutical Industries Ltd ₹215.63 4.5% COSTLIER
-
percompa 6mg tabletLinux Laboratories ₹222.37 7.8% COSTLIER
-
perampa 6mg tabletIntas Pharmaceuticals Ltd ₹245.40 19% COSTLIER
-
torpanel 6 tabletTorrent Pharmaceuticals Ltd ₹247.60 20% COSTLIER
-
perampil 6mg tabletAlkem Laboratories Ltd ₹340.30 65% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure epilepsy.
Fact: This medicine does not cure epilepsy; it helps control seizures when taken regularly as prescribed. - Myth: This medicine is safe to stop suddenly once seizures are controlled.
Fact: Stopping this medicine suddenly can cause withdrawal seizures. It must be tapered gradually under medical supervision. - Myth: This medicine is a first-line treatment for all seizures.
Fact: This medicine is usually used as add-on therapy when other antiepileptic drugs have not provided adequate seizure control.