Exinol 2 Tablet (Perampanel 2mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Thoughts of harming yourself or suicide
- Severe aggression or violent behaviour
- Rash, blisters, or peeling skin
- Yellowing of eyes or skin
- Severe dizziness with fainting or falls
- Seizures that do not stop or come in clusters
- Difficulty breathing or swelling of face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is hetram 2mg tablet used for?
This medicine is an anti-seizure medicine containing Perampanel 2 mg. It is used as an add-on treatment for partial-onset seizures and primary generalized tonic-clonic seizures in epilepsy patients. It works by blocking AMPA receptors in the brain to reduce abnormal electrical activity.
- Generic Name: Perampanel (2mg)
- Manufacturer: Hetero Healthcare Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hetram 2mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पेराम्पैनेल 2 मिलीग्राम की बनी है और मिर्गी के दौरे के इलाज में इस्तेमाल होती है। यह उन मरीजों के लिए दी जाती है जिनके दौरे अन्य दवाओं से पूरी तरह काबू में नहीं आते। यह दवा दिमाग में एएमपीए रिसेप्टर को ब्लॉक करके दौरे की गतिविधि को कम करती है। इसे आमतौर पर रात को सोने से पहले लिया जाता है। इस दवा को डॉक्टर की सलाह के बिना शुरू या बंद नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, नींद आना, थकान, चिड़चिड़ापन, गुस्सा आना, चलने में परेशानी और वजन बढ़ना शामिल हैं। कुछ लोगों को जी मिचलाना, उल्टी, सिरदर्द या धुंधला दिखाई देना भी हो सकता है। गंभीर दुष्प्रभाव कम होते हैं लेकिन आत्महत्या के विचार, गंभीर त्वचा प्रतिक्रिया या अत्यधिक चक्कर आना हो सकता है। अगर कोई भी दुष्प्रभाव गंभीर या लगातार बना रहे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें क्योंकि इससे दौरे बढ़ सकते हैं। इस दवा के साथ शराब बिल्कुल न पिएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी न चलाएं। अगर आपको मूड में बदलाव, गुस्सा या खुद को नुकसान पहुंचाने के विचार आएं तो तुरंत डॉक्टर को बताएं। गर्भवती महिलाएं या गर्भधारण की योजना बना रही महिलाएं डॉक्टर से सलाह लें।
💊 hetram 2mg tablet Uses & Benefits
[{"condition":"Partial-onset seizures (focal-onset seizures)","description":"Used as an add-on treatment in patients with epilepsy who have not achieved adequate seizure control with other anti-seizure medicines.","evidence":"Well-established"},{"condition":"Primary generalized tonic-clonic seizures","description":"Used as an add-on treatment in patients with idiopathic generalized epilepsy who continue to have generalized tonic-clonic seizures.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Refractory status epilepticus","description":"Sometimes used in hospital settings for emergency control of prolonged seizures when standard treatments fail.","evidence":"Limited"},{"condition":"Lennox-Gastaut syndrome","description":"Occasionally prescribed as an add-on therapy in this severe childhood epilepsy syndrome.","evidence":"Limited"}]
Primary treatment for: Epilepsy
Also treats: Partial-onset seizures, Primary generalized tonic-clonic seizures
📋 Drug Information
| Generic Name(s) | Perampanel (2mg) |
| Brand Name | hetram 2mg tablet |
| Manufacturer | Hetero Healthcare Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | AMPA glutamate receptor antagonist |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep in the original container, tightly closed. Protect from light and moisture. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively blocking AMPA receptors in the brain. AMPA receptors are a type of glutamate receptor that play a key role in the rapid transmission of excitatory signals between nerve cells. In epilepsy, excessive glutamate activity can lead to uncontrolled electrical discharges that cause seizures. By blocking these receptors, this medicine reduces the spread of abnormal electrical activity and helps to stabilise brain signalling. This action is different from many other anti-seizure medicines, which is why it can be effective when added to other treatments.
Mechanism Steps
💡 How to Take hetram 2mg tablet
Strength: 2 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults is 2 mg once daily at bedtime. The dose may be increased gradually by 2 mg at weekly intervals, depending on response and tolerability, up to a maximum of 12 mg once daily. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. The dose should be increased slowly and with caution. Close monitoring is recommended. |
| Renal Impairment | No dose adjustment is needed for mild to moderate kidney impairment. In severe kidney impairment, use with caution and consult your doctor for dose adjustment. |
| Hepatic Impairment | For mild to moderate liver impairment, the dose should be increased slowly and with caution. This medicine is contraindicated in severe liver impairment. |
| Maximum Daily Dose | 12 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hetram 2mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Carbamazepine | Major | |
| Phenytoin | Major | |
| Rifampicin | Major | |
| Oral contraceptives | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Carbamazepine
- Phenytoin
- Rifampicin
⚡ Moderate Interactions
- Oral contraceptives
- Alcohol
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Alcohol can increase the sedative effects, dizziness, and drowsiness caused by this medicine. It can also lower the seizure threshold, which may increase the risk of seizures. Combining alcohol with this medicine can impair judgment and coordination, making driving or operating machinery dangerous.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to Perampanel or any ingredient in the tablet","Severe liver impairment","Severe kidney impairment","Pregnancy unless clearly needed","Breastfeeding"]
⚠️ Warnings & Precautions
["May cause dizziness and drowsiness; avoid driving or operating machinery until you know how it affects you.","May cause mood changes, aggression, or suicidal thoughts; inform your doctor if these occur.","Do not stop this medicine suddenly as it may cause withdrawal seizures.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of falls.","Inform your doctor if you have liver or kidney problems.","This medicine may reduce the effectiveness of oral contraceptives."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor. Consult your doctor to discuss the risks and benefits.
💊 Overdose Management
Overdose of this medicine may cause severe dizziness, drowsiness, confusion, and loss of consciousness. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Contact your local poison control centre or go to the nearest emergency room.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
This medicine must only be taken exactly as prescribed by a qualified doctor. The dose should never be increased, decreased, or stopped suddenly without medical advice, because abrupt withdrawal can cause seizures to worsen. Alcohol should be avoided completely while taking this medicine, as it can increase dizziness, drowsiness, and the risk of seizures. People taking this medicine should not drive or operate heavy machinery until they know how it affects them. This medicine can cause mood changes, aggression, or thoughts of self-harm, so family members should be informed to watch for these signs. Women who are pregnant or planning pregnancy should discuss the risks and benefits with their doctor before continuing this medicine. Regular follow-up visits are important to monitor seizure control, side effects, and liver function. This medicine should be stored safely out of the reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, drowsiness, and falls. The dose should be increased slowly and with caution. Regular monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before starting or continuing this medicine. Effective contraception is recommended while taking this medicine. Your doctor will discuss the risks and benefits of continuing treatment during pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon and anaesthesiologist that you are taking this medicine before any surgery. Do not stop the medicine without medical advice. Your doctor may adjust the dose or timing around the surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine may interact with certain anaesthetics or sedatives used during dental work. Your dentist may need to adjust the treatment plan.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine, but caution is needed if you experience dizziness or drowsiness. Avoid swimming, cycling, or using heavy gym equipment alone until you know how the medicine affects you. Inform your exercise partner or trainer about your condition.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause dizziness and drowsiness, which may affect your ability to drive or operate machinery. It is important to avoid these activities until you know how the medicine affects you. Inform your employer about your condition if your job involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as suicidal thoughts, severe rash, or liver problems, seek immediate medical attention. Your doctor will decide if and when to stop the medicine, usually by gradually reducing the dose.
📅 Long-Term Use Effects
Long-term use of this medicine may be necessary for seizure control. Regular monitoring of liver function, kidney function, and mood is recommended. Some patients may experience weight gain or persistent drowsiness. The dose may need adjustment over time. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A high-fat, low-carbohydrate diet that may help reduce seizures in some patients, especially children.
Evidence: Well-established for certain types of epilepsyA device implanted under the skin that sends electrical signals to the vagus nerve to reduce seizures.
Evidence: Well-established for refractory epilepsySurgical removal of the brain area causing seizures, considered in certain cases.
Evidence: Well-established for selected patients💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine, especially live vaccines, while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. If crossing time zones, consult your doctor about adjusting the timing of your dose. Store it at room temperature and protect it from moisture. Check customs regulations for carrying prescription medicines to your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but its full anti-seizure effect may take several weeks to become apparent as the dose is gradually increased.
A: No, you should never stop this medicine suddenly. Stopping it abruptly can cause seizures to return or worsen. Always consult your doctor before making any changes.
A: This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor immediately if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for hetram 2mg tablet
View AllAlternative brands with exact same active ingredient:
-
perampil 2mg tabletAlkem Laboratories Ltd ₹60.00 33.3% CHEAPER
-
percompa 2mg tabletLinux Laboratories ₹97.00 7.8% COSTLIER
-
perampa 2mg tabletIntas Pharmaceuticals Ltd ₹121.60 35.1% COSTLIER
-
torpanel 2 tabletTorrent Pharmaceuticals Ltd ₹135.00 50% COSTLIER
-
exinol 2 tabletAlteus Biogenics Pvt Ltd ₹140.63 56.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure epilepsy permanently.
Fact: This medicine helps control seizures but does not cure epilepsy. It must be taken regularly as prescribed. - Myth: This medicine can be stopped once seizures are controlled.
Fact: Stopping this medicine suddenly can cause seizures to return or worsen. Always consult your doctor before stopping. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be avoided completely while taking this medicine as it increases sedation and seizure risk.
🔄 Alternative Options
Generic Alternatives
- Perampanel 2 mg tablet
Brand Alternatives
- Fycompa 2 mg tablet