Heparel 100IU Injection: Hepatitis B Vaccine for Prevention
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or wheezing after the injection
- Swelling of the face, lips, tongue, or throat
- A sudden drop in blood pressure or fainting
- A widespread rash with itching or hives
- High fever that does not settle
- Severe pain or swelling at the injection site that spreads
- Weakness, tingling, or difficulty walking after vaccination
If experiencing severe symptoms, call emergency services immediately.
What is hebexglob 100iu injection used for?
This medicine is a hepatitis B vaccine given as an injection to prevent hepatitis B infection. It works by helping the body make protective antibodies. It is given in a series of doses, usually three, and is safe for children and adults.
- Generic Name: Hepatitis B Vaccine (rDNA) (100IU)
- Manufacturer: Fusion Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hebexglob 100iu injection के बारे में (Hindi Summary)
उपयोग: यह दवा हेपेटाइटिस बी वायरस से होने वाले संक्रमण को रोकने के लिए दी जाती है। यह एक टीका है जो शरीर में वायरस के खिलाफ सुरक्षात्मक एंटीबॉडी बनाता है। यह नवजात शिशुओं, बच्चों, स्वास्थ्य कर्मचारियों, डायलिसिस रोगियों और उन लोगों को दी जाती है जिन्हें संक्रमण का खतरा अधिक होता है। यह इंजेक्शन के रूप में ऊपरी बांह या जांघ की मांसपेशी में लगाया जाता है। यह टीका पहले से मौजूद हेपेटाइटिस बी संक्रमण का इलाज नहीं करता।
साइड इफेक्ट्स: इस दवा के अधिकांश लोगों में कोई गंभीर दुष्प्रभाव नहीं होता। कुछ लोगों को इंजेक्शन वाली जगह पर दर्द, लालिमा या सूजन हो सकती है। हल्का बुखार, सिरदर्द, थकान और बेचैनी भी हो सकती है। ये आमतौर पर एक-दो दिन में ठीक हो जाते हैं। बहुत कम मामलों में गंभीर एलर्जी प्रतिक्रिया हो सकती है, जिसमें सांस लेने में कठिनाई, चेहरे या गले में सूजन हो सकती है। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह टीका केवल प्रशिक्षित स्वास्थ्य कर्मचारी द्वारा ही लगाया जाना चाहिए। अगर आपको पहले किसी टीके या यीस्ट से एलर्जी हुई है तो डॉक्टर को बताएं। तेज बुखार होने पर टीका लगवाने से पहले डॉक्टर से सलाह लें। गर्भवती महिलाएं डॉक्टर से चर्चा करके ही यह टीका लगवाएं। यह टीका हेपेटाइटिस ए, हेपेटाइटिस सी या अन्य लिवर संक्रमण से नहीं बचाता, इसलिए सुरक्षित आदतें अपनाएं। टीकाकरण का रिकॉर्ड संभालकर रखें।
💊 hebexglob 100iu injection Uses & Benefits
[{"condition":"Prevention of hepatitis B infection","description":"This medicine is given to prevent hepatitis B virus infection in children, adolescents, and adults who are at risk.","evidence":"Well-established"},{"condition":"Prevention of mother-to-child transmission of hepatitis B","description":"Newborns born to hepatitis B positive mothers receive this vaccine soon after birth, often with hepatitis B immunoglobulin, to reduce the risk of infection.","evidence":"Well-established"},{"condition":"Prevention of hepatitis B in healthcare workers","description":"Healthcare workers and laboratory staff who may come into contact with blood or body fluids are routinely vaccinated.","evidence":"Well-established"},{"condition":"Prevention of hepatitis B in dialysis and transplant patients","description":"People with kidney failure on dialysis or those awaiting organ transplant are at higher risk and are advised to complete the vaccination schedule.","evidence":"Well-established"},{"condition":"Prevention of hepatitis B in people with high-risk behaviours","description":"People who inject drugs, men who have sex with men, and people with multiple sexual partners are advised to receive this vaccine.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of hepatitis D infection","description":"Hepatitis D virus can only infect people who already have hepatitis B, so hepatitis B vaccination indirectly helps prevent hepatitis D.","evidence":"Well-established"}]
Primary treatment for: Hepatitis B infection (prevention)
Also treats: Hepatitis D infection (prevention), Liver cirrhosis due to hepatitis B (prevention), Hepatocellular carcinoma due to hepatitis B (prevention)
📋 Drug Information
| Generic Name(s) | Hepatitis B Vaccine (rDNA) (100IU) |
| Brand Name | hebexglob 100iu injection |
| Manufacturer | Fusion Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VACCINES |
| Action Class | Subunit (Purified antigen) |
| Route of Administration | Parenteral (intramuscular injection) |
| Storage | Store this medicine in a refrigerator at 2°C to 8°C. Do not freeze. Keep it in the original packaging to protect it from light. Do not use if it has been frozen. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | The World Health Organization recommends hepatitis B vaccination for all infants as part of routine immunisation, including a birth dose within 24 hours where possible. It also recommends vaccination for people at high risk of infection. |
| ICMR Guideline | The Indian Council of Medical Research and national immunisation guidelines recommend hepatitis B vaccination for all infants and for high-risk groups, including healthcare workers and people with chronic liver disease. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains hepatitis B surface antigen produced by recombinant DNA technology. After injection, the antigen is taken up by immune cells, which process it and present it to helper T cells. This activates B cells to produce specific antibodies against the hepatitis B surface antigen. The body also forms memory B and T cells, so that if the real hepatitis B virus enters the body later, the immune system can respond quickly and prevent infection. The vaccine does not contain live virus, so it cannot cause hepatitis B infection.
Mechanism Steps
💡 How to Take hebexglob 100iu injection
Strength: Injection containing hepatitis B vaccine (rDNA) 100 IU per dose.
Dosage Information
| Adult Dosage | For adults, this medicine is usually given as a 1 mL intramuscular injection into the deltoid muscle of the upper arm. The standard schedule is three doses: the first dose at a chosen date, the second dose one month later, and the third dose six months after the first. Some accelerated schedules may be used for travellers or people needing rapid protection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | For children and newborns, this medicine is given as an intramuscular injection, usually into the thigh in infants. The dose and schedule depend on the child's age and risk factors. Newborns born to hepatitis B positive mothers should receive the first dose within 24 hours of birth, along with hepatitis B immunoglobulin if available. Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults can receive this medicine using the same schedule as younger adults. The immune response may be slightly lower in older people, but vaccination is still recommended for those at risk. Dose must be individualized by a qualified clinician. |
| Renal Impairment | People with kidney disease, including those on dialysis, can receive this medicine. The dose and schedule are the same as for adults, but antibody levels should be checked because the response may be lower. Additional doses may be needed. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | People with liver disease can receive this medicine. No dose adjustment is required for liver disease. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | Not applicable. This vaccine is given as a single injection per visit, not as a daily dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hebexglob 100iu injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Immunosuppressants | Moderate | |
| Chemotherapy | Moderate |
⚡ Moderate Interactions
- Immunosuppressants (for example, high-dose corticosteroids, ciclosporin, tacrolimus)
- Antineoplastic chemotherapy
🍷 Alcohol Interaction
Alcohol does not directly interact with this medicine. However, heavy alcohol use can weaken the immune system and may reduce the body's response to the vaccine. It is advisable to avoid heavy drinking around the time of vaccination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe allergic reaction to a previous dose of this vaccine or to any of its components","Known severe allergy to yeast","Acute severe febrile illness (vaccination should be postponed until recovery)"]
⚠️ Warnings & Precautions
["This vaccine must be given by a trained healthcare professional only.","Epinephrine and emergency equipment must be available in case of anaphylaxis.","People with a bleeding disorder or those on blood thinners should be vaccinated with caution to reduce the risk of bleeding at the injection site.","People with a weakened immune system may not develop full protection and may need additional doses.","This vaccine does not protect against hepatitis A, hepatitis C, or other liver infections.","Do not use this vaccine if the vial or syringe appears damaged or the liquid is discoloured.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
This medicine is not expected to harm a breastfed baby because the vaccine antigen is not passed into breast milk in a harmful form. Breastfeeding women can receive this vaccine if it is indicated.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given as a single injection by a healthcare professional. If more than the recommended dose is given accidentally, watch for signs of allergic reaction and treat symptomatically. There is no specific antidote.
⏰ Missed Dose
If you miss a scheduled dose of this vaccine, contact your doctor or vaccination centre as soon as possible to arrange the next dose. Do not restart the entire schedule from the beginning. The vaccination course should be completed according to the recommended schedule.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional in a setting where emergency equipment is available. Tell your doctor if you have ever had an allergic reaction to a vaccine, yeast, or any medicine. Inform your doctor if you have a high fever, a bleeding disorder, a weakened immune system, or if you are taking blood-thinning medicines. Pregnant women should discuss the benefits and risks with their doctor before receiving this vaccine. This vaccine does not protect against hepatitis A, hepatitis C, or other liver infections, so continue to follow safe practices such as using condoms and not sharing needles. Keep a record of your vaccination dates and bring it to every visit. Do not self-administer this injection at home.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults can receive this vaccine safely. The immune response may be slightly lower than in younger people, but vaccination is still recommended for those at risk. No dose adjustment is needed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, you can receive this vaccine if you are at risk of hepatitis B infection. Discuss the timing with your doctor. There is no need to delay pregnancy after receiving this vaccine.
🏥 Post-Surgery Considerations
This vaccine can be given after surgery if needed. Inform your surgeon and anaesthetist about your vaccination status. There are no specific restrictions related to surgery.
🦷 Dental Procedures
There are no specific restrictions for dental procedures after receiving this vaccine. Inform your dentist about your vaccination status if relevant.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There is no specific exercise restriction after receiving this vaccine. If you feel tired or have a mild fever, you may wish to rest for a day. You can resume your normal exercise routine as soon as you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This vaccine does not usually affect your ability to work or drive. Some people may feel mild tiredness or headache for a day, which may make driving or operating machinery slightly less comfortable. If you feel unwell, rest until you feel better.
🛑 When to Stop This Medicine
You should complete the full vaccination schedule as advised by your doctor. Do not stop the schedule on your own. If you experience a severe allergic reaction or another serious side effect, seek immediate medical attention and discuss with your doctor whether further doses should be given.
📅 Long-Term Use Effects
Long-term use of this vaccine is not applicable because it is given as a short series of injections. The long-term benefit is protection against hepatitis B infection, which can prevent chronic liver disease and liver cancer. In healthy people, protection lasts for many years. People with weakened immune systems may need additional doses or periodic antibody testing. No serious long-term side effects have been established from the available information.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
This provides immediate but short-term protection and is often given together with the vaccine after exposure, such as in newborns of infected mothers.
Evidence: Well-establishedThis vaccine protects against both hepatitis A and hepatitis B in a single product.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine is itself a vaccine. It can be given at the same time as other routine vaccines, but at different injection sites. Live vaccines can be given at the same time or at least four weeks apart. If you are planning to receive other vaccines, inform your doctor so that the schedule can be planned properly.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze the vaccine
✅ DO
Keep in the original packaging
❌ DON'T
Do not transfer to another container
✅ DO
Protect from light
❌ DON'T
Do not leave in direct sunlight
✅ DO
Check the expiry date before use
❌ DON'T
Do not use if the liquid is discoloured or contains particles
✈️ Traveling with This Medicine
If you are travelling, carry this vaccine in its original packaging with a prescription or vaccination record. It must be stored in a refrigerator at 2°C to 8°C, so use a cool box or vaccine carrier during travel. Avoid freezing the vaccine. If you need to complete a vaccination schedule while abroad, carry your vaccination card so that the next dose can be given on time. Check the entry requirements of your destination country, as some countries require proof of hepatitis B vaccination for certain travellers or workers.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Protective antibodies usually begin to appear within two to four weeks after the first dose, but full protection is achieved only after completing the recommended series of doses.
A: Available evidence does not suggest an increased risk of birth defects. However, you should discuss the benefits and risks with your doctor before receiving this vaccine.
A: Contact your doctor or vaccination centre as soon as possible to arrange the next dose. Do not restart the entire schedule from the beginning.
A: Alcohol does not directly interact with this vaccine, but heavy drinking can weaken the immune response. It is best to avoid heavy alcohol use around the time of vaccination.
A: Protection after a complete course is long-lasting and is believed to last for many years, possibly lifelong, in healthy people. People with weakened immunity may need booster doses.
🤔 Common Patient Concerns
🔄 Substitutes for hebexglob 100iu injection
View AllAlternative brands with exact same active ingredient:
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hepaglob 100iu injectionSun Pharmaceutical Industries Ltd ₹840.00 87.9% CHEAPER
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heparel 100iu injectionReliance Life Sciences ₹6,000.00 13.9% CHEAPER
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samhep 100iu injectionSamarth Life Sciences Pvt Ltd ₹6,900.00 1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Hepatitis B vaccine can cause hepatitis B.
Fact: This vaccine does not contain live virus, so it cannot cause hepatitis B infection. - Myth: Hepatitis B vaccine is only for children.
Fact: Adults, especially healthcare workers and people at high risk, also need this vaccine. - Myth: Once you get the first dose, you are fully protected.
Fact: Full protection usually requires completion of the recommended series of doses. - Myth: Hepatitis B vaccine causes infertility.
Fact: There is no evidence that this vaccine causes infertility.
🔄 Alternative Options
Generic Alternatives
- Hepatitis B Vaccine (rDNA) 100 IU injection
Brand Alternatives
- Heparel 100IU Injection