halox f cream - Halometasone (0.05% w/w) + Fusidic Acid (2% w/w) medicine

Execare-F Cream: A Complete Guide to Uses, Side Effects, and Safety

No reviews yet
🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
🤰 Pregnancy Category Not classified by FDA letter categories. Use only if clearly needed and after consulting a doctor. Topical corticosteroids should be used in the smallest amount for the shortest duration. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat, or difficulty breathing.
  • Signs of systemic corticosteroid effects such as unusual weight gain, fatigue, or high blood sugar.
  • Worsening of skin infection or spread of redness and swelling.
  • Severe burning, itching, or rash at the application site.
  • Skin thinning, easy bruising, or stretch marks appearing on treated areas.
  • Yellowing of skin or eyes, or dark urine, which may indicate liver problems.

If experiencing severe symptoms, call emergency services immediately.

What is halox f cream used for?

This medicine is a topical cream combining halometasone (a corticosteroid) and fusidic acid (an antibiotic). It is used to treat inflammatory skin conditions that are infected or at risk of infection, such as infected eczema or dermatitis. Apply a thin layer to the affected area as directed by your doctor, usually once or twice daily. Do not use for longer than prescribed.

  • Generic Name: Halometasone (0.05% w/w) + Fusidic Acid (2% w/w)
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 halox f cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें हेलोमेटासोन (एक स्टेरॉयड) और फ्यूसिडिक एसिड (एक एंटीबायोटिक) शामिल हैं। इसका उपयोग त्वचा की सूजन और बैक्टीरियल संक्रमण के इलाज के लिए किया जाता है, जैसे कि संक्रमित एक्जिमा या डर्मेटाइटिस। यह खुजली, लालिमा और सूजन को कम करता है और संक्रमण को साफ करता है। इसे डॉक्टर के निर्देशानुसार प्रभावित हिस्से पर पतली परत में लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, या लालिमा शामिल हैं। ये आमतौर पर अस्थायी होते हैं। दुर्लभ मामलों में त्वचा का पतला होना, खिंचाव के निशान, या गंभीर एलर्जी हो सकती है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस क्रीम को केवल प्रभावित त्वचा पर लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क से बचें। लगाने से पहले और बाद में हाथ धोएं। डॉक्टर के निर्देश के बिना इसे ढकें नहीं। निर्धारित अवधि से अधिक इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 halox f cream Uses & Benefits

[{"condition":"Infected eczema","description":"Reduces inflammation and treats bacterial infection in eczema lesions.","evidence":"Well-established"},{"condition":"Infected dermatitis","description":"Helps control inflammation and bacterial overgrowth in various types of dermatitis.","evidence":"Well-established"},{"condition":"Infected psoriasis","description":"May be used short-term to manage inflamed psoriatic plaques with secondary bacterial infection.","evidence":"Moderate"},{"condition":"Bacterial skin infections with inflammation","description":"Treats conditions like impetiginized eczema or infected insect bites.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Infected seborrheic dermatitis","description":"Occasionally prescribed when bacterial infection complicates seborrheic dermatitis.","evidence":"Limited"}]

Primary treatment for: Infected dermatitis

Also treats: Infected eczema, Infected psoriasis, Bacterial skin infections with inflammation

📋 Drug Information

Generic Name(s)Halometasone (0.05% w/w) + Fusidic Acid (2% w/w)
Brand Namehalox f cream
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore below 30°C. Do not freeze. Keep the tube tightly closed when not in use. Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer of this medicine only to the affected area and rub it in gently.
2
Do not use this medicine on the face, groin, or underarms unless specifically instructed by your doctor.
3
Complete the full course as prescribed, even if symptoms improve, to prevent recurrence of infection.
4
Avoid using airtight dressings over the treated area unless your doctor advises otherwise.
5
If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine.
6
Keep this medicine away from the eyes, mouth, and other mucous membranes.
7
Do not use this medicine for longer than prescribed, as prolonged use can cause skin thinning.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Red, itchy, inflamed skin with signs of infection (pus, crusting)
This medicine is commonly prescribed for infected eczema or dermatitis.
Likely Use
❌
Fungal infection (ringworm, athlete's foot)
This medicine is not effective against fungal infections and may worsen them.
Not Primary
❌
Viral infection (cold sores, chickenpox)
This medicine is contraindicated for viral skin infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionHalometasone and fusidic acid are absorbed through the skin. The extent of absorption depends on the area treated, the condition of the skin, and the duration of use. Systemic absorption is generally low with normal use but can increase with prolonged use, large areas, or broken skin.
DistributionOnce absorbed, halometasone is distributed throughout the body, primarily bound to plasma proteins. Fusidic acid also distributes into tissues, but detailed distribution data for the topical combination are not well established.
Protein BindingHalometasone is highly protein-bound (over 90%). Fusidic acid is also highly protein-bound (over 95%).
MetabolismHalometasone is metabolized in the liver, primarily by cytochrome P450 enzymes. Fusidic acid is metabolized in the liver, mainly by glucuronidation and other pathways.
Half-LifeThe elimination half-life of halometasone is not well established for topical use. Fusidic acid has a half-life of approximately 5-6 hours after systemic administration.
ExcretionMetabolites of halometasone are excreted mainly in urine and feces. Fusidic acid is excreted primarily in bile and feces, with a small amount in urine.
BioavailabilitySystemic bioavailability of halometasone and fusidic acid after topical application is low but variable, depending on skin integrity and application site.
Onset of ActionImprovement in itching and redness may be noticed within a few hours to days. Full therapeutic effect for the infection typically takes several days.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe anti-inflammatory effect lasts for several hours after application. The antibiotic effect persists as long as adequate concentrations are maintained in the skin.

How It Works

This medicine combines a corticosteroid and an antibiotic. Halometasone binds to glucocorticoid receptors in the skin, reducing the production of inflammatory chemicals and suppressing immune responses that cause redness, swelling, and itching. Fusidic acid works by inhibiting bacterial protein synthesis, specifically by blocking elongation factor G, which prevents bacteria from multiplying and helps clear the infection.

Mechanism Steps

1
Halometasone binds to glucocorticoid receptors: Halometasone enters skin cells and binds to cytoplasmic glucocorticoid receptors, forming a complex that moves into the nucleus.
2
Suppression of inflammatory genes: The complex inhibits the transcription of pro-inflammatory genes and promotes the production of anti-inflammatory proteins, reducing redness, swelling, and itching.
3
Fusidic acid inhibits bacterial protein synthesis: Fusidic acid binds to bacterial elongation factor G, preventing the translocation step in protein synthesis, which stops bacterial growth.
4
Combined effect: The anti-inflammatory action of halometasone reduces tissue damage and itching, while fusidic acid eliminates the bacterial infection, leading to faster healing.

💡 How to Take halox f cream

Strength: Cream containing halometasone 0.05% w/w and fusidic acid 2% w/w.

1Wash your hands thoroughly before and after applying the cream.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected skin and rub it in gently.
4Do not cover the area with a bandage or dressing unless your doctor tells you to.
5Avoid contact with eyes, mouth, and other mucous membranes.
6Use the cream exactly as prescribed. Do not use more or less than directed.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area once or twice daily, or as directed by your doctor. The frequency and duration of treatment depend on the condition being treated and your response to therapy. Do not use for more than 2 weeks without medical advice. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. Use in children should be limited to the smallest amount for the shortest duration, as children are more susceptible to systemic corticosteroid effects.
Elderly DosageNo specific dosage adjustments are required for elderly patients. However, use with caution and for the shortest duration possible due to increased risk of skin thinning and systemic effects.
Renal ImpairmentNo dosage adjustment is required for renal impairment when used topically. However, if systemic absorption is significant, monitor for adverse effects.
Hepatic ImpairmentNo specific dosage adjustment is required for hepatic impairment when used topically. However, use with caution due to potential hepatotoxicity of fusidic acid if absorbed systemically.
Maximum Daily DoseNot established from the available information. Use only as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of halox f cream

✅ Common Side Effects

Application site burning or stinging (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Itching (Common (1-10%))
Avoid scratching. If itching worsens, contact your doctor.
Redness or rash (Common (1-10%))
May indicate irritation. If it spreads or worsens, stop use and consult a doctor.
Dryness or flaking of skin (Uncommon (0.1-1%))
Use a gentle moisturizer if advised by your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help if you experience swelling of face, lips, throat, or difficulty breathing.
Skin thinning (atrophy) or stretch marks (Rare (<0.1%))
Report to your doctor if you notice skin thinning, easy bruising, or stretch marks. May require discontinuation.
Systemic corticosteroid effects (e.g., high blood sugar, adrenal suppression) (Rare (<0.1%))
Contact your doctor if you experience unusual fatigue, weight gain, or increased thirst. Blood tests may be needed.
Worsening of infection or superinfection (Rare (<0.1%))
If the infection spreads or new symptoms appear, stop use and consult a doctor immediately.

⚠️ Rare Side Effects

Contact dermatitis
Discontinue use and consult a doctor if you develop a new rash at the application site.
Folliculitis
Keep the area clean and consult your doctor if it persists.
Hypertrichosis (excessive hair growth)
Usually reversible after stopping the medicine. Consult your doctor if concerned.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other topical corticosteroids Major
CYP3A4 inhibitors Moderate
Diuretics Moderate
Hepatotoxic drugs Major

🚨 Major Interactions

  • Other topical corticosteroids
  • Nephrotoxic or hepatotoxic drugs

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • Diuretics

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol may worsen skin conditions; consult your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to halometasone, fusidic acid, or any component of the cream.","Viral skin infections (e.g., herpes simplex, chickenpox).","Fungal skin infections (e.g., ringworm, athlete's foot).","Tuberculous skin infections.","Acne vulgaris, rosacea, and perioral dermatitis.","Use on open wounds or broken skin.","Use in the eye or on mucous membranes."]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on the face, groin, or underarms unless directed by a doctor, as these areas are more prone to side effects.","Do not use for longer than prescribed, especially in children, as it may cause systemic effects.","Do not cover with airtight dressings unless instructed.","If irritation or allergic reaction occurs, discontinue use and consult a doctor.","Use with caution in patients with liver disease or those taking hepatotoxic drugs.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known if halometasone or fusidic acid pass into breast milk after topical use. However, systemic absorption is low. To be safe, do not apply to the breast area before breastfeeding. Consult your doctor.

💊 Overdose Management

Overdose from topical application is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and signs of systemic corticosteroid effects. Treatment is supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine only to the affected skin area and avoid contact with eyes, mouth, and other mucous membranes. Wash your hands thoroughly before and after applying, unless your hands are the treated area. Do not cover the treated area with airtight dressings unless instructed by your doctor, as this can increase absorption and side effects. Do not use this medicine for longer than prescribed, and do not use it on large areas of the body without medical advice. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to skin thinning and systemic effects of corticosteroids. Use the smallest effective amount for the shortest duration and monitor for side effects.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Topical corticosteroids should be used with caution during pregnancy, and only if the potential benefit justifies the potential risk to the fetus.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before using this medicine on or near the surgical site, as it may affect wound healing and increase the risk of infection.

🦷 Dental Procedures

No specific precautions for dental procedures. However, inform your dentist if you are using this medicine, especially if you have a history of corticosteroid use.

💚 Lifestyle Tips for Better Results

🏃
Keep your skin well moisturized with a gentle, fragrance-free moisturizer.
🥗
Avoid scratching the affected area to prevent worsening of infection.
😴
Wear loose, breathable clothing to reduce irritation.
💧
Avoid known triggers that worsen your skin condition, such as harsh soaps or allergens.
🧘
Manage stress through relaxation techniques, as stress can flare skin conditions.
🌞
Get adequate sleep to support skin healing.

🏋️ Exercise Considerations

You can continue exercising, but avoid activities that cause excessive sweating or friction on the treated area. Shower after exercise and reapply the cream if needed, as directed by your doctor.

🥗 Diet Recommendations

Include anti-inflammatory foods like fruits, vegetables, and omega-3 rich fish.
Stay well hydrated to keep skin healthy.
Limit processed foods and added sugars, which may worsen inflammation.
Consider probiotic-rich foods to support gut and skin health.

💼 Impact on Daily Work & Life

This medicine is applied to the skin and is unlikely to affect your ability to work or drive. However, if you experience any dizziness or unusual symptoms, avoid driving or operating machinery until you feel better.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms worsen, if you develop a new rash, or if you experience any serious side effects. Do not stop abruptly if you have been using it for a long time; your doctor may advise tapering to prevent rebound inflammation.

📅 Long-Term Use Effects

Prolonged use of this medicine, especially on large areas or under occlusive dressings, can lead to skin thinning, stretch marks, and systemic absorption of the corticosteroid, which may cause adrenal suppression, high blood sugar, or Cushing's syndrome. Long-term use of fusidic acid can lead to antibiotic resistance. Regular monitoring by a doctor is advised if extended use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Emollients and moisturizers

Regular use of emollients can help repair the skin barrier and reduce the need for topical steroids.

Evidence: Well-established
Antibacterial washes

May help reduce bacterial load on the skin in mild cases.

Evidence: Moderate
Phototherapy

For chronic conditions like psoriasis, phototherapy may be an alternative under medical supervision.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, if you are using this medicine on large areas or for prolonged periods, consult your doctor before receiving live vaccines, as corticosteroids can suppress the immune system.

📦 Storage Guide

✅ DO

Store below 30°C in a dry place.

❌ DON'T

Do not freeze or refrigerate.

✅ DO

Keep the tube tightly closed when not in use.

❌ DON'T

Do not transfer to another container.

✅ DO

Protect from direct sunlight and moisture.

❌ DON'T

Do not store in the bathroom.

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it below 30°C and protect it from direct sunlight. If you are crossing time zones, continue applying as prescribed; there is no need to adjust the schedule for topical creams. Keep it in your carry-on luggage if flying, as checked baggage may be exposed to extreme temperatures.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with infected eczema on her hands.
She was prescribed this medicine to apply twice daily. After 3 days, the itching and redness reduced significantly. She completed the 7-day course as directed and the infection cleared. She noted that washing her hands before application and avoiding scratching helped.
💡 Lesson: Consistent application and good hygiene are key to clearing infected eczema.
👤 A 50-year-old man with infected dermatitis on his leg.
He used the cream as prescribed for 10 days. The infection resolved, but he developed mild skin thinning at the site. His doctor advised him to stop the cream and use a moisturizer. The thinning improved over time.
💡 Lesson: Prolonged use can cause skin thinning; always follow the prescribed duration and report any skin changes to your doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice reduced itching and redness within a few days. The infection usually clears within 1-2 weeks. If no improvement after 7 days, consult your doctor.

Q: Can I use this cream on my face?

A: It is not recommended for use on the face unless specifically prescribed by your doctor, as facial skin is more sensitive and prone to side effects.

Q: Is it safe to use during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed, in the smallest amount for the shortest duration.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this cream on my face?
  • How long can I safely use this cream?
  • Will it leave a scar?
  • Can I use it if I am pregnant?
  • Does it interact with other skin products?
  • What if I forget to apply a dose?

🔄 Substitutes for halox f cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This cream can be used for any skin infection.
    Fact: It is only for bacterial infections and inflammatory conditions. It does not treat fungal or viral infections.
  • Myth: More cream means faster healing.
    Fact: Applying more than prescribed can increase side effects without improving results.
  • Myth: It is safe to use indefinitely.
    Fact: Prolonged use can cause skin thinning and other side effects. Use only as prescribed.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Halometasone 0.05% + Fusidic acid 2%","potency":"Potent corticosteroid","use":"Infected inflammatory skin conditions"},{"medicine":"Hydrocortisone + Fusidic Acid","composition":"Hydrocortisone 1% + Fusidic acid 2%","potency":"Mild corticosteroid","use":"Mild infected dermatitis"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory