Agmacof Syrup: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in sputum or vomit
- Severe abdominal pain or persistent vomiting
- Difficulty breathing or chest pain
- Swelling of face, lips, or throat
- Confusion, extreme weakness, or irregular heartbeat
- Decreased urine output or signs of dehydration
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is hacodryl syrup used for?
This medicine is an expectorant cough syrup containing ammonium chloride and sodium citrate. It helps loosen thick mucus and relieve productive cough. It is usually taken orally every 4 to 6 hours, but the dose must be individualized by a doctor.
- Generic Name: Ammonium Chloride (138mg) + Sodium Citrate (57.03mg)
- Manufacturer: Habitare Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hacodryl syrup के बारे में (Hindi Summary)
उपयोग: यह दवा एक कफ सिरप है जिसमें अमोनियम क्लोराइड और सोडियम सिट्रेट होता है। यह गाढ़े बलगम को पतला करके खांसी के साथ बलगम निकालने में मदद करती है। इसका उपयोग सर्दी, ब्रोंकाइटिस और श्वसन संक्रमण के कारण होने वाली बलगम वाली खांसी में किया जाता है। यह दवा केवल उन्हीं लोगों के लिए है जिन्हें बलगम वाली खांसी है, सूखी खांसी के लिए नहीं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में असहजता, दस्त, नींद आना और सिरदर्द शामिल हैं। कभी-कभी मुंह में धातु जैसा स्वाद, प्यास लगना और बार-बार पेशाब आना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन अगर सांस लेने में तकलीफ, चेहरे पर सूजन, या बहुत ज्यादा कमजोरी महसूस हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। ज्यादा मात्रा में न लें क्योंकि इससे पेट में जलन और शरीर में एसिड-बेस असंतुलन हो सकता है। दवा लेने के साथ भरपूर पानी पिएं। खाली पेट दवा न लें। अगर खांसी 7 दिन से ज्यादा रहे तो डॉक्टर से सलाह लें। गर्भवती और स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इसका इस्तेमाल न करें।
💊 hacodryl syrup Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps loosen and thin bronchial secretions, making it easier to cough out phlegm.","evidence":"Traditionally used; supportive evidence"},{"condition":"Common cold with chest congestion","description":"Provides symptomatic relief by reducing mucus viscosity and soothing the throat.","evidence":"Traditionally used; supportive evidence"},{"condition":"Acute bronchitis","description":"Used as an adjunct to help clear mucus from the airways in acute bronchitis.","evidence":"Limited evidence"},{"condition":"Upper respiratory tract infections with cough","description":"May help relieve cough associated with excess mucus in the throat and chest.","evidence":"Traditionally used; supportive evidence"}]
Off-label uses: [{"condition":"Metabolic alkalosis (historical use)","description":"Ammonium chloride has been used historically to correct metabolic alkalosis, but this is a specialized hospital use and not applicable to this cough syrup.","evidence":"Limited; not for self-medication"}]
Primary treatment for: Productive cough
Also treats: Common cold, Acute bronchitis, Upper respiratory tract infection
📋 Drug Information
| Generic Name(s) | Ammonium Chloride (138mg) + Sodium Citrate (57.03mg) |
| Brand Name | hacodryl syrup |
| Manufacturer | Habitare Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Do not refrigerate unless specified on the label. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Ammonium chloride acts as an expectorant by irritating the gastric mucosa, which reflexively stimulates the bronchial glands to secrete more respiratory tract fluid. This increased fluid helps dilute and thin thick mucus, making it easier to cough up. Sodium citrate acts as a mild mucolytic and demulcent; it helps break down mucus by reducing its viscosity and also soothes irritated throat tissues. Together, they improve the clearance of mucus from the airways and provide symptomatic relief from productive cough.
Mechanism Steps
💡 How to Take hacodryl syrup
Strength: Each 5 mL of syrup contains Ammonium Chloride 138 mg and Sodium Citrate 57.03 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 to 10 mL taken orally every 4 to 6 hours, not exceeding 4 doses in 24 hours. However, the exact dose and frequency depend on the severity of the cough, the patient's age, kidney and liver function, and other medical conditions. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate beyond the recommended duration. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially electrolyte imbalance and drowsiness. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose adjustment may be required based on renal function. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose adjustment may be required based on hepatic function. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose for adults is generally 40 mL of this syrup in 24 hours, but this must be confirmed by a qualified clinician. Do not exceed the dose recommended by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hacodryl syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Diuretics | Major | |
| Corticosteroids | Major | |
| MAOIs | Major | |
| Antacids | Moderate | |
| Aspirin | Moderate | |
| Lithium | Moderate | |
| Tetracycline | Minor | |
| Fluoroquinolones | Minor |
🚨 Major Interactions
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- Corticosteroids
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Antacids
- Aspirin
- Lithium
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach irritation, nausea, and drowsiness when taken with this medicine. It is advisable to avoid alcohol while using this product.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe kidney disease","Severe liver disease","Metabolic acidosis","Hypersensitivity to ammonium chloride, sodium citrate, or any component of this medicine","Patients on a low-salt diet","Children below the age recommended by the doctor"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Use with caution in patients with heart disease, kidney disease, or liver disease.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor if cough persists for more than 7 days or is accompanied by fever, rash, or persistent headache.","Do not use for a dry, non-productive cough.","Keep out of reach of children.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, metabolic acidosis, electrolyte imbalance, and dehydration. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and may include monitoring of electrolytes, fluids, and acid-base balance. Do not induce vomiting unless advised by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly in the dose and for the duration advised by your doctor. Do not exceed the recommended dose because ammonium chloride can cause stomach irritation and acid-base imbalance. Drink plenty of water while taking this medicine to help loosen mucus and prevent dehydration. Avoid taking it on an empty stomach if it causes nausea. Do not use this medicine for a dry cough or for more than a few days without medical advice. If you have kidney disease, liver disease, heart disease, or are on a low-salt diet, inform your doctor before using this medicine. Pregnant and breastfeeding women should consult a doctor before use. Keep this medicine out of the reach of children. Do not drive or operate heavy machinery if you feel drowsy or dizzy after taking it.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and electrolyte imbalance. They should use it with caution and under medical supervision. Dose adjustment may be needed based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy is not well established. Your doctor may recommend alternative treatments.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before using this medicine. It may interact with other medications or affect recovery. Do not self-medicate.
🦷 Dental Procedures
This medicine may cause dry mouth or altered taste. Inform your dentist if you are taking this medicine before any dental procedure. It is generally safe to continue, but follow your doctor's advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you have a productive cough, as it may worsen breathlessness. Light activity like walking is fine if you feel up to it. Consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is best to rest at home while you have an active cough to prevent spreading infection to others.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if your cough does not improve within 7 days, if it worsens, or if you develop fever, rash, or difficulty breathing. Do not stop prescribed antibiotics or other medicines without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of ammonium chloride can lead to metabolic acidosis, electrolyte imbalance, and increased stomach irritation. If your cough persists for more than 7 days, consult a doctor to determine the underlying cause. Regular monitoring of electrolytes and kidney function may be needed if used for extended periods under medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Inhaling steam can help loosen mucus and relieve chest congestion.
Evidence: Traditionally used; supportive evidenceHelps clear nasal passages and reduce postnasal drip.
Evidence: Well-establishedSoothes the throat and may reduce cough frequency.
Evidence: Some evidence💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are unwell with a fever, it is best to postpone vaccination until you recover. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place away from direct sunlight during travel. If you are traveling across time zones, continue taking the medicine at the same intervals as prescribed, but consult your doctor if you are unsure. Do not leave it in a hot car or checked luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The expectorant effect usually begins within 30 to 60 minutes, but you may need a few doses to notice significant relief.
A: Yes, it is best taken with food or a snack to reduce stomach upset.
A: Pediatric dosing is not established. Consult a pediatrician before giving this medicine to a child.
A: If you remember within half the dosing interval, take it. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Consult your doctor before using this medicine during pregnancy. The safety is not well established.
🤔 Common Patient Concerns
🔄 Substitutes for hacodryl syrup
View AllAlternative brands with exact same active ingredient:
-
respidil syrupOverseas Healthcare Pvt Ltd ₹31.00 65.2% CHEAPER
-
cascahist syrupCasca Remedies Pvt Ltd ₹32.00 64% CHEAPER
-
colzer syrupColumbus Biotech ₹45.00 49.4% CHEAPER
-
bentoril syrupBindlysh Biotec Ltd ₹47.00 47.2% CHEAPER
-
belcof syrupGreen Cross Remedies ₹47.70 46.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This syrup can cure any type of cough.
Fact: This medicine is only for productive cough with thick mucus. It is not effective for dry cough or cough due to asthma. - Myth: More syrup means faster relief.
Fact: Taking more than the recommended dose can cause serious side effects like metabolic acidosis and stomach irritation. - Myth: It is safe to take this syrup for weeks.
Fact: This medicine is for short-term use. Prolonged use can cause electrolyte imbalance. Consult a doctor if cough persists beyond 7 days.
🔄 Alternative Options
Generic Alternatives
- Ammonium chloride + sodium citrate syrup (generic)