Granry-cl Tablet: Comprehensive Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Swelling of face, lips, or throat
- Decreased urine output
- Irregular heartbeat or palpitations
- Yellowing of skin or eyes
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is granry-cl tablet used for?
This medicine is a combination of Cilnidipine and Irbesartan used to treat high blood pressure. It works by relaxing blood vessels and reducing the workload on the heart.
- Generic Name: Cilnidipine (5mg) + Irbesartan (150mg)
- Manufacturer: AAR ESS Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 granry-cl tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर और हृदय पर दबाव कम करके रक्तचाप को नियंत्रित करती है। यह उन वयस्कों के लिए है जिनका रक्तचाप एक दवा से नियंत्रित नहीं हो रहा है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, थकान और पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के अनुकूल होने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आपको बेहोशी, पेशाब में कमी, या चेहरे और गले में सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। बिना सलाह के डोज न बदलें या दवा बंद न करें। शराब से बचें क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। अचानक उठने से बचें। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और इलेक्ट्रोलाइट्स की जांच कराएं।
💊 granry-cl tablet Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Hypertension
Also treats: Chronic kidney disease, Diabetes with hypertension, Heart failure
📋 Drug Information
| Generic Name(s) | Cilnidipine (5mg) + Irbesartan (150mg) |
| Brand Name | granry-cl tablet |
| Manufacturer | AAR ESS Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Cilnidipine blocks L-type and N-type calcium channels, leading to vasodilation and reduced peripheral resistance. Irbesartan selectively blocks angiotensin II AT1 receptors, inhibiting vasoconstriction and aldosterone secretion. The combined effect lowers blood pressure more effectively than either agent alone.
Mechanism Steps
💡 How to Take granry-cl tablet
Strength: Tablet, Cilnidipine 5 mg + Irbesartan 150 mg
Dosage Information
| Adult Dosage | The usual adult dose is one tablet once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. |
| Renal Impairment | Dose adjustment may be needed in patients with severe renal impairment. Consult your doctor. |
| Hepatic Impairment | Contraindicated in severe hepatic impairment. Use with caution in mild to moderate impairment. |
| Maximum Daily Dose | One tablet daily (Cilnidipine 5 mg + Irbesartan 150 mg). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of granry-cl tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Potassium supplements | Major | |
| NSAIDs | Major | |
| Diuretics | Moderate | |
| CYP3A4 inhibitors | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Potassium supplements
- NSAIDs
⚡ Moderate Interactions
- Diuretics
- CYP3A4 inhibitors
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect and increase dizziness. It is advisable to avoid or limit alcohol consumption.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Severe hepatic impairment","Biliary obstructive disorders","Hypersensitivity to any component","Concomitant use with aliskiren in patients with diabetes"]
⚠️ Warnings & Precautions
["Avoid in pregnancy and breastfeeding.","Use with caution in elderly and those with kidney or liver disease.","Monitor potassium levels regularly.","Avoid sudden discontinuation.","May cause dizziness; avoid driving until you know how it affects you."]
🤱 Lactation Safety
Not recommended. Consult your doctor for alternative options.
💊 Overdose Management
Overdose may cause severe hypotension and electrolyte imbalance. Seek immediate medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop or change the dose without consulting your doctor. Avoid alcohol as it can increase dizziness and low blood pressure. Stand up slowly to prevent dizziness. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Regular monitoring of blood pressure, kidney function, and electrolytes is important. Keep all follow-up appointments.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to blood pressure lowering effects. Start with a lower dose and monitor closely for dizziness and falls.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine before surgery. It may need to be temporarily stopped.
🦷 Dental Procedures
Inform your dentist about this medicine. It may cause dry mouth or dizziness during dental procedures. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is encouraged, but avoid sudden strenuous activities that may cause dizziness. Stay hydrated and monitor your blood pressure before and after exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when you start treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with caution.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored. Regular check-ups of blood pressure, kidney function, and electrolytes are recommended. It may reduce the risk of cardiovascular events. Do not stop without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help lower blood pressure and complement medication.
Evidence: Well-establishedACE inhibitors, beta-blockers, or diuretics may be alternatives based on individual needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry your medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage. Store at room temperature and avoid extreme temperatures. If crossing time zones, consult your doctor about adjusting the timing. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1-2 hours, but full effects may take a few weeks.
A: No, hypertension is a chronic condition. Stopping medication can cause blood pressure to rise again. Consult your doctor before making any changes.
A: If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: Hypertension is a chronic condition. Stopping medication can cause blood pressure to rise again. Always consult your doctor before stopping. - Myth: This medicine causes kidney damage.
Fact: When used as prescribed, it can actually protect the kidneys. Regular monitoring is important.
🔄 Alternative Options
Generic Alternatives
- Cilnidipine + Irbesartan generic tablets