gmac m2 tablet er - Glimepiride (2mg) + Metformin (500mg) medicine

Gmac M2 Tablet ER

4.6 (17 reviews)
๐Ÿญ Macsys LifeSciences ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is gmac m2 tablet er used for?

Gmac M2 Tablet ER is a combination medicine containing Glimepiride and Metformin, used to improve blood sugar control in adults with type 2 diabetes mellitus. It helps the body use insulin more effectively and reduces glucose production in the liver.

  • Generic Name: Glimepiride (2mg) + Metformin (500mg)
  • Manufacturer: Macsys LifeSciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š gmac m2 tablet er Uses & Benefits

Detailed medical information is being added to our database.

๐Ÿ“‹ Drug Information

Generic Name(s)Glimepiride (2mg) + Metformin (500mg)
Brand Namegmac m2 tablet er
ManufacturerMacsys LifeSciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassInformation pending
Route of AdministrationOral
StorageRoom temperature (15-30ยฐC), away from moisture
Shelf LifeAs per manufacturer

๐Ÿ’ก How to Take gmac m2 tablet er

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of gmac m2 tablet er

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Hypoglycemia (low blood sugar)
  • Headache
  • Weight gain

๐Ÿšจ Serious Side Effects

  • Lactic acidosis (symptoms: muscle pain, trouble breathing, stomach pain)
  • Severe allergic reaction (rash, itching, swelling)
  • Liver problems (yellowing skin/eyes, dark urine)

โš ๏ธ Rare Side Effects

  • Vitamin B12 deficiency (with long-term use)
  • Blood disorders (decreased platelets/white blood cells)

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Insulin Major Increased risk of hypoglycemia
Corticosteroids Moderate Reduced hypoglycemic effect
Cimetidine Minor Increased metformin levels

๐Ÿšจ Major Interactions

  • Insulin
  • Other sulfonylureas
  • Alcohol

โšก Moderate Interactions

  • Corticosteroids (e.g., prednisone)
  • Diuretics (e.g., furosemide)
  • Beta-blockers (e.g., propranolol)

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Ranolazine
  • Topiramate

๐Ÿฝ๏ธ Food Interactions

Take this medicine with meals to reduce gastrointestinal side effects like nausea and diarrhea. Avoid high-sugar foods as they can counteract the medicine's effects. Consistent carbohydrate intake helps maintain stable blood sugar levels.

๐Ÿท Alcohol Interaction

Alcohol can increase the risk of lactic acidosis and hypoglycemia. It is strongly advised to avoid alcohol while taking Gmac M2 Tablet ER. If you drink, limit intake and monitor blood sugar closely, but it's safest to abstain.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
High
Heart
Low

๐Ÿšซ Contraindications

Do not use Gmac M2 Tablet ER if you have severe kidney disease (eGFR < 30 mL/min), metabolic acidosis (including lactic acidosis), severe liver disease, or a history of allergic reaction to Glimepiride, Metformin, or sulfonylureas. It is also contraindicated in patients with type 1 diabetes or diabetic ketoacidosis.

โš ๏ธ Warnings & Precautions

This medicine can cause lactic acidosis, a rare but serious condition, especially in patients with kidney impairment, liver disease, or those who consume alcohol excessively. Symptoms include muscle pain, difficulty breathing, stomach pain, and feeling very weak. Stop taking and seek immediate medical help if these occur. Also, monitor blood sugar levels to avoid hypoglycemia, especially when skipping meals or exercising more than usual.

๐Ÿ’Š Overdose Management

Overdose may cause severe hypoglycemia (low blood sugar) or lactic acidosis. Symptoms of hypoglycemia include sweating, shakiness, confusion, and rapid heartbeat. If conscious, consume sugar or glucose tablets. If unconscious, seek emergency medical help immediately. Lactic acidosis requires urgent hospital treatment.

โฐ Missed Dose

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose to make up for a missed one.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 11, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 11, 2026

Effective and reliable. Worked as expected.

Verified User Jul 11, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 11, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 11, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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