Glykind-M Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Rapid breathing, muscle pain, extreme tiredness, or stomach pain (possible lactic acidosis)
- Severe hypoglycemia with confusion, unconsciousness, or seizures
- Severe abdominal pain radiating to the back with nausea and vomiting (possible pancreatitis)
- Swelling of face, lips, tongue, or throat, or difficulty breathing (allergic reaction)
- Yellowing of skin or eyes, dark urine, or severe fatigue (liver problems)
- Decreased urine output or swelling in legs (kidney problems)
If experiencing severe symptoms, call emergency services immediately.
What is glicaday-m tablet used for?
This medicine is a combination of gliclazide and metformin used to treat type 2 diabetes. It lowers blood sugar by increasing insulin release and improving insulin sensitivity. It should be taken with meals and requires regular monitoring.
- Generic Name: Gliclazide (80mg) + Metformin (500mg)
- Manufacturer: Care Formulation Labs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 glicaday-m tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। इसमें ग्लिक्लाजाइड और मेटफॉर्मिन दो दवाएं होती हैं जो मिलकर ब्लड शुगर को कंट्रोल करती हैं। ग्लिक्लाजाइड पैंक्रियाज से इंसुलिन निकालने में मदद करती है और मेटफॉर्मिन शरीर में इंसुलिन के असर को बढ़ाती है। यह दवा उन लोगों के लिए है जिनका शुगर सिर्फ डाइट और एक दवा से कंट्रोल नहीं हो रहा। इसे खाने के साथ लेना चाहिए।
साइड इफेक्ट्स: आम साइड इफेक्ट्स में शुगर कम होना (हाइपोग्लाइसीमिया), जी मिचलाना, दस्त, पेट में गड़बड़ी और मुंह में धातु जैसा स्वाद शामिल हैं। गंभीर साइड इफेक्ट्स में लैक्टिक एसिडोसिस, गंभीर हाइपोग्लाइसीमिया, पैंक्रियाटाइटिस और एलर्जी शामिल हैं। अगर सांस तेज चले, मांसपेशियों में दर्द, अत्यधिक थकान या पेट में तेज दर्द हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा खाने के साथ लें। खाना न छोड़ें। ब्लड शुगर नियमित रूप से जांचें। शराब न पिएं क्योंकि इससे लैक्टिक एसिडोसिस और शुगर कम होने का खतरा बढ़ता है। किडनी या लिवर की बीमारी हो तो डॉक्टर को बताएं। कोई भी नई दवा शुरू करने से पहले डॉक्टर से सलाह लें। शुगर कम होने पर तुरंत ग्लूकोज या मिठाई लें।
💊 glicaday-m tablet Uses & Benefits
- [{"condition":"Type 2 diabetes mellitus","description":"Used as an add-on therapy in adults whose blood sugar is not controlled by diet, exercise, and a single oral antidiabetic drug.
- It helps lower fasting and post-meal blood glucose levels.","evidence":"Well-established"},{"condition":"Type 2 diabetes with insulin resistance","description":"The metformin component improves insulin sensitivity, while gliclazide increases insulin secretion, making this combination useful in patients with both defects.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Polycystic ovary syndrome (PCOS)","description":"Metformin alone is sometimes used off-label in PCOS to improve insulin resistance and menstrual regularity, but the combination with gliclazide is not standard for this use.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Insulin resistance, Metabolic syndrome
📋 Drug Information
| Generic Name(s) | Gliclazide (80mg) + Metformin (500mg) |
| Brand Name | glicaday-m tablet |
| Manufacturer | Care Formulation Labs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. Guidelines generally recommend metformin as first-line therapy for type 2 diabetes, with sulfonylureas as add-on options. |
| ICMR Guideline | Not established from the available information. ICMR guidelines for type 2 diabetes recommend individualized therapy, with metformin as initial therapy and sulfonylureas as add-on if needed. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Gliclazide binds to sulfonylurea receptors on pancreatic beta cells, closing ATP-sensitive potassium channels, which leads to membrane depolarization, calcium influx, and increased insulin release. Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and enhances peripheral insulin sensitivity by activating AMP-activated protein kinase (AMPK). The combined effect lowers blood glucose levels through both insulin secretion and improved insulin action.
Mechanism Steps
💡 How to Take glicaday-m tablet
Strength: Each tablet contains Gliclazide 80 mg and Metformin 500 mg.
Dosage Information
| Adult Dosage | The usual starting dose is one tablet taken once or twice daily with meals, depending on your blood sugar levels and kidney function. Your doctor may adjust the dose gradually to achieve target glucose control. The maximum daily dose should not exceed what your doctor prescribes. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially the risk of hypoglycemia and lactic acidosis. Doses should be started low and increased cautiously based on kidney function and blood glucose monitoring. |
| Renal Impairment | This medicine is contraindicated in severe kidney impairment (eGFR <30 mL/min/1.73 m²). In mild to moderate kidney impairment, dose adjustments and close monitoring are required. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose adjustment may be necessary, and regular monitoring of liver function is advised. Avoid in severe liver disease. |
| Maximum Daily Dose | The maximum daily dose is determined by your doctor based on your condition and kidney function. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of glicaday-m tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Iodinated contrast media | Major | |
| Beta-blockers | Moderate | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| ACE inhibitors | Moderate | |
| Cimetidine | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Alcohol
- Iodinated contrast media
- Other sulfonylureas or insulin
⚡ Moderate Interactions
- Beta-blockers
- Diuretics (thiazides, loop)
- Corticosteroids
- ACE inhibitors
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it increases the risk of lactic acidosis and can cause dangerous drops in blood sugar. It may also worsen stomach upset and liver problems.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe kidney impairment (eGFR
⚠️ Warnings & Precautions
["Risk of lactic acidosis with metformin, especially in patients with kidney impairment, liver disease, or conditions causing tissue hypoxia.","Hypoglycemia risk is higher with gliclazide, especially in elderly, malnourished, or those with kidney or liver impairment.","Temporarily discontinue before surgery or iodinated contrast procedures as advised.","Avoid excessive alcohol intake.","Monitor kidney function regularly.","Use with caution in patients with adrenal or pituitary insufficiency.","May cause vitamin B12 deficiency with long-term use."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose can cause severe hypoglycemia and lactic acidosis. Symptoms include shakiness, sweating, confusion, rapid breathing, and stomach pain. If overdose is suspected, seek emergency medical care immediately. Treatment is supportive and may include glucose administration and dialysis for metformin accumulation.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is less than half the dosing interval away. If more than half the interval has passed, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine with meals to lower the chance of stomach upset and low blood sugar. Do not skip meals while on this medicine. Check your blood sugar regularly as advised by your doctor. Avoid alcohol because it can increase the risk of lactic acidosis and hypoglycemia. Tell your doctor if you have kidney or liver problems, or if you are scheduled for surgery or an imaging test with contrast dye. Do not start or stop any other medicine without consulting your doctor. Carry a source of fast-acting sugar, such as glucose tablets or candy, to treat low blood sugar. Wear a medical alert card or bracelet stating you have diabetes and are taking this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia and lactic acidosis. Doses should be started low and increased cautiously. Regular monitoring of kidney function and blood sugar is essential. Avoid skipping meals.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. This medicine is generally not recommended during pregnancy; insulin is the preferred treatment. Your doctor will adjust your therapy.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily stopped before surgery or procedures involving contrast dye. Follow your doctor's instructions carefully. Blood sugar monitoring is crucial during the perioperative period.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. Dental procedures can affect your blood sugar and eating habits. You may need to adjust your medication timing on the day of the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar. Check your blood sugar before exercising and carry a fast-acting sugar source. Avoid strenuous exercise if your blood sugar is very low or very high. Consult your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause low blood sugar, which can affect your ability to drive or operate machinery. Be cautious until you know how it affects you. Carry a sugar source and inform your colleagues about your condition. Regular meals and monitoring can help you manage your work routine safely.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your blood sugar is well controlled and your doctor advises stopping, follow their guidance. Stopping suddenly can cause blood sugar to rise.
📅 Long-Term Use Effects
Long-term use may lead to vitamin B12 deficiency due to metformin, requiring periodic monitoring. Kidney function should be checked regularly. The risk of hypoglycemia persists, especially in elderly patients. Cardiovascular outcomes are generally favorable with gliclazide. Regular follow-up with your doctor is essential to adjust therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Lifestyle modifications are the foundation of diabetes management and can help reduce medication needs.
Evidence: Well-establishedDPP-4 inhibitors, SGLT2 inhibitors, or GLP-1 receptor agonists may be alternatives based on individual needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
People with diabetes should stay up to date with recommended vaccines, including influenza, pneumococcal, and hepatitis B vaccines. Consult your doctor about the best timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If traveling across time zones, consult your doctor about adjusting the timing of doses. Store at room temperature and avoid direct sunlight. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few hours, but the full effect on HbA1c may take 2-3 months of consistent use.
A: It depends on the severity of kidney disease. Your doctor will check your kidney function and may adjust the dose or choose a different medicine.
A: Symptoms include shakiness, sweating, confusion, rapid heartbeat, and hunger. Treat promptly with fast-acting sugar.
🤔 Common Patient Concerns
🔄 Substitutes for glicaday-m tablet
View AllAlternative brands with exact same active ingredient:
-
bioformin 80mg/500mg tabletBiogenetic Pharmaceuticals ₹7.03 85.5% CHEAPER
-
bioformin plus 80 mg/500 mg tabletBiological E Ltd ₹10.29 78.8% CHEAPER
-
micromol p tabletSouthshourne Corporation India ₹11.25 76.9% CHEAPER
-
metbetic g tabletCadila Pharmaceuticals Ltd ₹13.29 72.7% CHEAPER
-
cyzide m 80mg/500mg tabletCyper Drugs & Pharmaceuticals Pvt Ltd ₹15.19 68.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps control blood sugar but does not cure diabetes. It must be continued along with diet and exercise. - Myth: You can stop taking this medicine once your sugar levels are normal.
Fact: Stopping without medical advice can cause blood sugar to rise again. Always consult your doctor before stopping. - Myth: This medicine is safe for everyone with diabetes.
Fact: It is not suitable for people with type 1 diabetes, severe kidney or liver disease, or certain other conditions.
🔄 Alternative Options
Generic Alternatives
- Gliclazide 80 mg + Metformin 500 mg tablet (generic)
Brand Alternatives
- Glykind-M Tablet
- Diamicron LM
- Glimestar-M
- Ziglim-M
- Gliclazide Metformin Tablet