Azlore P 4mg/325mg Tablet: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe skin rash with blisters or peeling
If experiencing severe symptoms, call emergency services immediately.
What is glad p 4mg/325mg tablet used for?
This medicine is a combination of lornoxicam and paracetamol used for short-term relief of moderate to severe pain and inflammation. It works by reducing prostaglandins that cause pain and swelling. Take it with food, avoid alcohol, and do not exceed the prescribed dose.
- Generic Name: Lornoxicam (4mg) + Paracetamol (325mg)
- Manufacturer: Gladcare Formulations Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 glad p 4mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लोर्नोक्सिकैम और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर दर्द और सूजन के अल्पकालिक उपचार के लिए किया जाता है। यह जोड़ों के दर्द, मांसपेशियों के दर्द, दांत दर्द, मासिक धर्म के दर्द, और सर्जरी के बाद के दर्द में राहत देती है। यह दवा सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे भोजन के साथ लें और शराब से बचें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, एलर्जी प्रतिक्रिया, लीवर या किडनी की समस्या शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन या दूध के साथ लें ताकि पेट की जलन कम हो। निर्धारित खुराक से अधिक न लें। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और लीवर की समस्या का खतरा बढ़ सकता है। यदि आपको पेट के अल्सर, किडनी या लीवर की बीमारी, हृदय रोग, या अस्थमा है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 glad p 4mg/325mg tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as muscle strains, sprains, and back pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain following surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from moderate to severe toothache and pain after dental procedures.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces pain and improves joint mobility in osteoarthritis of the knee, hip, and hand.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps manage pain and inflammation associated with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Fever","description":"Paracetamol component may reduce fever, but this combination is not primarily indicated for fever alone.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Dysmenorrhea, Post-operative pain, Dental pain
📋 Drug Information
| Generic Name(s) | Lornoxicam (4mg) + Paracetamol (325mg) |
| Brand Name | glad p 4mg/325mg tablet |
| Manufacturer | Gladcare Formulations Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Lornoxicam is a non-steroidal anti-inflammatory drug that reversibly inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, leading to decreased production of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesic and antipyretic effects without significant anti-inflammatory action. Together, they provide enhanced pain relief through different pathways.
Mechanism Steps
💡 How to Take glad p 4mg/325mg tablet
Strength: Each tablet contains lornoxicam 4 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally one to two times daily, depending on the severity of pain and the prescribing doctor's instructions. The maximum recommended daily dose is two tablets in 24 hours. This medicine should be taken with food or milk to reduce stomach upset. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose or duration of treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration possible. Consult a doctor for dose adjustments. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose reduction may be necessary. Consult a doctor for individualized dosing. Avoid use in severe kidney disease. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose reduction may be necessary. Avoid use in severe liver disease. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is two tablets (lornoxicam 8 mg + paracetamol 650 mg) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of glad p 4mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Fluconazole | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- ACE inhibitors and ARBs
- Diuretics
- SSRIs
- CYP2C9 inhibitors (e.g., fluconazole)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver damage, especially when combined with paracetamol and NSAIDs. It can also worsen drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to lornoxicam, paracetamol, or any other NSAID","Active or history of peptic ulcer or gastrointestinal bleeding","Severe liver disease or severe kidney disease","Severe heart failure","Third trimester of pregnancy","Children under 18 years of age (safety not established)","Concurrent use with other NSAIDs","History of asthma, urticaria, or allergic reaction after taking aspirin or other NSAIDs"]
⚠️ Warnings & Precautions
["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration of treatment.","Use with caution in the elderly due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma.","Do not drive or operate machinery if you experience dizziness or drowsiness.","Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.","Do not take other pain relievers or NSAIDs without consulting your doctor.","Stop taking this medicine and seek medical attention if you experience signs of allergic reaction or gastrointestinal bleeding."]
🤱 Lactation Safety
Not established from the available information. Lornoxicam may pass into breast milk. Paracetamol is considered safe during breastfeeding when used at recommended doses. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe nausea, vomiting, abdominal pain, drowsiness, and potentially liver damage (from paracetamol) and kidney damage (from lornoxicam). Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be given if within 1-2 hours of ingestion. N-acetylcysteine is the antidote for paracetamol overdose and should be administered as soon as possible. Monitor liver and kidney function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine with food or milk to reduce the risk of stomach upset. Do not exceed the prescribed dose or duration of treatment. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver problems. Do not take other pain relievers or NSAIDs without consulting your doctor, as this can increase the risk of side effects. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration possible. Monitor kidney and liver function regularly. Consult a doctor for dose adjustments.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy if you are taking this medicine. NSAIDs may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Paracetamol is considered safe when used at recommended doses.
🏥 Post-Surgery Considerations
This medicine may be prescribed for post-operative pain. Follow your surgeon's instructions carefully. Inform your surgeon if you have a history of stomach ulcers, kidney or liver disease, or bleeding disorders.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding during dental work. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may worsen pain while taking this medicine. Listen to your body and rest if you feel dizzy or drowsy. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Inform your employer if you need to take this medicine during work hours.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, allergic reactions, or if your pain does not improve within 7 days. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney problems, liver damage, and cardiovascular events. Regular monitoring of liver and kidney function is recommended. Use the lowest effective dose for the shortest duration possible. Consult your doctor if you need to take this medicine for more than a few days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help relieve localized pain and inflammation.
Evidence: ModerateMay help reduce pain in some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccination timing while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep enough supply for your trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: No, it should be taken with food or milk to reduce the risk of stomach upset and bleeding.
A: Do not take other painkillers or NSAIDs without consulting your doctor, as it may increase the risk of side effects.
A: This medicine is usually prescribed for short-term use. Do not take it for longer than recommended without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for glad p 4mg/325mg tablet
View AllAlternative brands with exact same active ingredient:
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norsant 4mg/325mg tabletPleasant Pharmaceuticals Pvt Ltd ₹40.50 33.5% CHEAPER
-
raplor p tabletZyphar's Pharmaceuticals Pvt Ltd ₹42.19 30.8% CHEAPER
-
lorshil sp tabletPrashil Life Sciences Pvt Ltd ₹45.00 26.2% CHEAPER
-
l ber p 4mg/325mg tabletCuber Lifesciences ₹55.00 9.7% CHEAPER
-
lorworm p 4mg/325mg tabletCadwell Pharma Private Limited ₹56.25 7.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food or milk to reduce the risk of stomach upset and bleeding. - Myth: More tablets mean faster pain relief.
Fact: Taking more than the prescribed dose increases the risk of serious side effects without providing better pain relief. - Myth: It is safe to take this medicine with alcohol.
Fact: Alcohol increases the risk of stomach bleeding and liver damage when taken with this medicine. - Myth: This medicine can be used for long-term pain management without monitoring.
Fact: Long-term use requires regular monitoring of liver and kidney function and should be under a doctor's supervision.
🔄 Alternative Options
Generic Alternatives
- Lornoxicam + Paracetamol
Brand Alternatives
- Azlore P 4mg/325mg Tablet