Glycomet-GP 2 Tablet PR: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Rapid breathing, muscle pain, extreme tiredness, or stomach pain with nausea and vomiting (possible lactic acidosis)
- Confusion, seizures, or loss of consciousness (severe hypoglycemia)
- Yellowing of skin or eyes, dark urine, or right upper abdominal pain (liver problems)
- Unusual tiredness, pale skin, or yellowing of eyes (hemolytic anemia)
- Rash, itching, swelling of face, lips, or throat, or difficulty breathing (allergic reaction)
- Severe abdominal pain radiating to the back (pancreatitis)
- Decreased urine output or swelling in legs (kidney problems)
If experiencing severe symptoms, call emergency services immediately.
What is genericart glimepiride+metformin+pioglitazone 2mg/500mg/15mg tablet sr used for?
This medicine is a combination of Glimepiride 2 mg and Metformin 500 mg used to treat type 2 diabetes. It lowers blood sugar by increasing insulin release and improving insulin sensitivity. Take it with meals as prescribed. Do not skip meals. Avoid alcohol. Monitor blood sugar regularly.
- Generic Name: Glimepiride (2mg) + Metformin (500mg)
- Manufacturer: Swast Aushadhi Seva Generic Medicine Store
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 genericart glimepiride+metformin+pioglitazone 2mg/500mg/15mg tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा ग्लाइमेपिराइड 2 मिलीग्राम और मेटफॉर्मिन 500 मिलीग्राम का संयोजन है, जिसका उपयोग टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए किया जाता है। यह रक्त शर्करा को नियंत्रित करने में मदद करती है जब अकेले आहार, व्यायाम और एक दवा से पर्याप्त नियंत्रण नहीं हो पाता। ग्लाइमेपिराइड अग्न्याशय से इंसुलिन निकालने को बढ़ावा देता है, जबकि मेटफॉर्मिन लीवर में ग्लूकोज बनने को कम करता है और शरीर की इंसुलिन के प्रति संवेदनशीलता बढ़ाता है। यह दवा डॉक्टर के पर्चे पर ही लेनी चाहिए। इसे भोजन के साथ लें। शराब से बचें। नियमित रूप से ब्लड शुगर की जांच करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में कम रक्त शर्करा (हाइपोग्लाइसीमिया), जी मिचलाना, दस्त, पेट में असहजता, मुंह में धातु जैसा स्वाद और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में लैक्टिक एसिडोसिस (दुर्लभ लेकिन जानलेवा), गंभीर हाइपोग्लाइसीमिया, एलर्जी प्रतिक्रियाएं और रक्त विकार शामिल हैं। यदि आपको तेज सांस लेने में कठिनाई, मांसपेशियों में दर्द, अत्यधिक थकान, या पेट दर्द के साथ उल्टी हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें ताकि पेट की परेशानी और कम रक्त शर्करा का खतरा कम हो। दवा लेते समय भोजन न छोड़ें। कम रक्त शर्करा के लक्षणों के लिए तुरंत काम करने वाली शर्करा जैसे ग्लूकोज टैबलेट या कैंडी साथ रखें। शराब से बचें क्योंकि इससे लैक्टिक एसिडोसिस और हाइपोग्लाइसीमिया का खतरा बढ़ सकता है। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। बिना डॉक्टर की सलाह के दवा की खुराक न बदलें। नियमित रूप से ब्लड शुगर की जांच करें।
💊 genericart glimepiride+metformin+pioglitazone 2mg/500mg/15mg tablet sr Uses & Benefits
[{"condition":"Type 2 diabetes mellitus","description":"Used as an add-on therapy to diet and exercise to improve glycemic control in adults whose blood sugar is not controlled with metformin alone or other single agents.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Type 2 diabetes mellitus
📋 Drug Information
| Generic Name(s) | Glimepiride (2mg) + Metformin (500mg) |
| Brand Name | genericart glimepiride+metformin+pioglitazone 2mg/500mg/15mg tablet sr |
| Manufacturer | Swast Aushadhi Seva Generic Medicine Store |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Glimepiride binds to sulfonylurea receptors on pancreatic beta cells, causing closure of ATP-sensitive potassium channels, membrane depolarization, calcium influx, and increased insulin secretion. Metformin decreases hepatic glucose production by inhibiting gluconeogenesis, reduces intestinal glucose absorption, and improves peripheral insulin sensitivity by increasing glucose uptake in skeletal muscle and fat. The combination addresses both insulin deficiency and insulin resistance.
Mechanism Steps
💡 How to Take genericart glimepiride+metformin+pioglitazone 2mg/500mg/15mg tablet sr
Strength: Tablet containing Glimepiride 2 mg and Metformin 500 mg.
Dosage Information
| Adult Dosage | The usual starting dose is one tablet once daily with a meal, but the exact dose and frequency must be individualized by a qualified clinician based on your blood sugar levels, kidney function, liver function, and other medications. Do not self-adjust the dose. Your doctor may increase the dose gradually based on your response and tolerance. The maximum recommended dose is generally 2 mg glimepiride and 1000 mg metformin twice daily, but this may vary. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are at increased risk of hypoglycemia and lactic acidosis. Start with a lower dose and titrate slowly based on renal function and blood sugar levels. Regular monitoring of kidney function is essential. |
| Renal Impairment | Dose adjustment is required in renal impairment. Metformin is contraindicated if eGFR is below 30 mL/min/1.73 m². For eGFR 30-45, metformin should be used with caution and dose reduction may be needed. Glimepiride should be used with caution. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Use with caution in mild to moderate hepatic impairment. Metformin is contraindicated in severe hepatic impairment. Dose adjustment may be needed. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is generally 4 mg glimepiride and 2000 mg metformin, but this must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of genericart glimepiride+metformin+pioglitazone 2mg/500mg/15mg tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Contrast media | Major | |
| Diuretics | Major | |
| Beta-blockers | Moderate | |
| ACE inhibitors | Moderate | |
| Corticosteroids | Moderate | |
| Thiazide diuretics | Moderate | |
| NSAIDs | Minor | |
| MAO inhibitors | Minor | |
| Cationic drugs | Moderate |
🚨 Major Interactions
- Alcohol
- Contrast media (iodinated)
- Diuretics
- Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin)
⚡ Moderate Interactions
- Beta-blockers
- ACE inhibitors
- Corticosteroids
- Thiazide diuretics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it increases the risk of lactic acidosis and can cause severe hypoglycemia. It may also worsen liver function and interfere with blood sugar control.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Risk of lactic acidosis: rare but serious; seek immediate medical help if symptoms occur.","Risk of hypoglycemia: especially with skipped meals, alcohol, or excessive exercise.","Renal function should be assessed before and during treatment.","Avoid alcohol consumption.","Temporarily discontinue before surgery or contrast procedures as advised.","May cause vitamin B12 deficiency with long-term use; monitor levels.","Elderly patients are at higher risk of hypoglycemia and lactic acidosis.","Not recommended for use in children.","Use with caution in patients with heart failure, liver disease, or adrenal insufficiency."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause severe hypoglycemia and lactic acidosis. Symptoms include confusion, seizures, rapid breathing, and stomach pain. Seek immediate medical attention. Treatment includes supportive care, glucose administration for hypoglycemia, and hemodialysis for metformin overdose if indicated.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine with meals to reduce stomach upset and lower the risk of hypoglycemia. Do not skip meals while on this medicine. Carry a fast-acting sugar source like glucose tablets or candy to treat low blood sugar. Avoid alcohol as it can increase the risk of lactic acidosis and hypoglycemia. Inform your doctor about all other medicines, especially those for blood pressure, heart, and infections. Do not change the dose without consulting your doctor. Monitor your blood sugar regularly as advised. Report any persistent nausea, muscle pain, or difficulty breathing immediately. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia and lactic acidosis. Start with a lower dose and titrate slowly. Monitor kidney function regularly. Be alert for symptoms of low blood sugar, which may be atypical in the elderly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. This medicine is not recommended during pregnancy. Insulin is generally preferred for managing diabetes during pregnancy. Your doctor will adjust your treatment plan.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily discontinued before surgery due to the risk of lactic acidosis and hypoglycemia. Your doctor will provide specific instructions. Monitor blood sugar closely after surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. Dental procedures can affect blood sugar levels. You may need to adjust your medication or meal timing. Monitor blood sugar before and after the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar. Check your blood sugar before and after exercise, especially if you are on this medicine. Carry a fast-acting sugar source. Avoid intense exercise if your blood sugar is very low or very high. Stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause low blood sugar, which can affect your ability to drive or operate machinery. Be cautious until you know how it affects you. Take regular breaks and snacks if your work is physically demanding. Inform your employer about your condition and treatment.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects like lactic acidosis or severe hypoglycemia, seek immediate medical help. Your doctor may adjust the dose or switch to a different medicine based on your condition.
📅 Long-Term Use Effects
Long-term use may lead to vitamin B12 deficiency, which can cause anemia and nerve damage. Regular monitoring of vitamin B12 levels is recommended. Kidney function should be checked at least annually. The risk of lactic acidosis increases with prolonged use, especially in patients with kidney or liver disease. Blood sugar control should be reassessed periodically, and the dose may need adjustment over time.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are the cornerstone of diabetes management and can reduce the need for medication.
Evidence: Well-establishedDPP-4 inhibitors, SGLT2 inhibitors, or GLP-1 receptor agonists may be alternatives based on individual needs.
Evidence: Well-establishedMay be needed if oral agents fail to control blood sugar.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
People with diabetes are at higher risk of infections. Ensure you are up to date with vaccinations, including influenza, pneumococcal, and hepatitis B vaccines. Consult your doctor about the best timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If traveling across time zones, consult your doctor about adjusting the timing of doses. Store at room temperature and avoid direct sunlight. Carry enough supply for the entire trip plus extra. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few hours, but it may take several weeks to see the full effect on HbA1c. Your doctor will monitor your progress.
A: It depends on the severity of kidney disease. Metformin is contraindicated in severe renal impairment. Your doctor will check your kidney function and adjust the dose or choose a different medicine.
A: Take 15 grams of fast-acting sugar (e.g., 3-4 glucose tablets, 1/2 cup juice). Wait 15 minutes and recheck. If still low, repeat. Seek medical help if symptoms persist.
A: No, do not stop without consulting your doctor. Your sugar is normal because of the medicine. Stopping suddenly can cause high blood sugar and complications.
🤔 Common Patient Concerns
🔄 Substitutes for genericart glimepiride+metformin+pioglitazone 2mg/500mg/15mg tablet sr
View AllAlternative brands with exact same active ingredient:
-
metpride 2 mg/500 mg tabletAlkem Laboratories Ltd ₹8.12 93.9% CHEAPER
-
glynet-m2 tabletZeelab Pharmacy Pvt Ltd ₹9.38 92.9% CHEAPER
-
glimpil mf 2 mg/500 mg tabletPsychotropics India Ltd ₹18.75 85.8% CHEAPER
-
davapride mf 2mg/500mg tablet srDavaindia Generic Pharmacy ₹20.00 84.9% CHEAPER
-
drmet g drmet g2 tablet srDR Best pharmaceuticals Pvt Ltd ₹20.63 84.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without food.
Fact: It should be taken with meals to reduce stomach upset and risk of low blood sugar. - Myth: This medicine can cure diabetes permanently.
Fact: It helps control blood sugar but does not cure diabetes. Lifestyle changes and ongoing treatment are needed. - Myth: If I feel fine, I can stop taking this medicine.
Fact: Stopping without medical advice can cause blood sugar to rise and lead to complications. - Myth: This medicine is safe for everyone with diabetes.
Fact: It is not for type 1 diabetes, severe kidney or liver disease, or during pregnancy without medical advice.
🔄 Alternative Options
Generic Alternatives
- Glimepiride + Metformin combination tablets from other manufacturers
Brand Alternatives
- Glycomet-GP 2 Tablet PR