gabarace-m tablet - Gabapentin (300mg) + Methylcobalamin (0.5mg) medicine

Alfagaba 300mg Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Race Pharmaceuticals pvt ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Gabapentin is classified as Pregnancy Category C by the FDA. There are no adequate well-controlled studies in pregnant women. This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Methylcobalamin is generally considered safe in pregnancy when used at recommended doses. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High for gabapentin in neuropathic pain; moderate for methylcobalamin in neuropathy.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden onset of severe drowsiness or difficulty breathing.
  • Swelling of the face, lips, or throat.
  • Suicidal thoughts or self-harm behavior.
  • Severe abdominal pain radiating to the back.
  • Decreased urine output or swelling in the legs.
  • Unusual bruising or bleeding.
  • Muscle pain with dark urine.
  • New or worsening seizures.

If experiencing severe symptoms, call emergency services immediately.

What is gabarace-m tablet used for?

This medicine is a combination of gabapentin and methylcobalamin used to treat neuropathic pain. Gabapentin reduces abnormal nerve signals, while methylcobalamin supports nerve repair. It is taken orally, usually once or twice daily, and should not be stopped suddenly.

  • Generic Name: Gabapentin (300mg) + Methylcobalamin (0.5mg)
  • Manufacturer: Race Pharmaceuticals pvt ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gabarace-m tablet के बारे में (Hindi Summary)

उपयोग: यह दवा गैबापेंटिन और मिथाइलकोबालामिन का संयोजन है, जिसका उपयोग न्यूरोपैथिक दर्द (नसों का दर्द) के इलाज के लिए किया जाता है। यह मधुमेह से होने वाले नसों के दर्द, दाद के बाद होने वाले दर्द, और विटामिन बी12 की कमी से जुड़े न्यूरोलॉजिकल लक्षणों में प्रभावी है। यह दवा नसों को शांत करती है और उनकी मरम्मत में मदद करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, नींद आना, थकान, और अस्थिरता शामिल हैं। कुछ लोगों को धुंधली दृष्टि, मुँह सूखना, या जी मिचलाना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई, या आत्महत्या के विचार आ सकते हैं। ऐसा होने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें, इससे withdrawal के लक्षण हो सकते हैं। शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गुर्दे की बीमारी हो तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को ठंडी और सूखी जगह पर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 gabarace-m tablet Uses & Benefits

[{"condition":"Diabetic peripheral neuropathy","description":"Helps reduce burning, tingling, and shooting pain in the feet and hands caused by nerve damage from diabetes.","evidence":"Well-established"},{"condition":"Postherpetic neuralgia","description":"Relieves persistent nerve pain that can occur after a shingles infection.","evidence":"Well-established"},{"condition":"Neuropathic pain of other origins","description":"May be used for nerve pain due to spinal cord injury, multiple sclerosis, or chemotherapy.","evidence":"Moderate"},{"condition":"Vitamin B12 deficiency with neurological symptoms","description":"Methylcobalamin component helps correct B12 deficiency and supports nerve health.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed to reduce frequency of migraines, though evidence is limited.","evidence":"Limited"},{"condition":"Restless legs syndrome","description":"May help reduce symptoms in some patients, but not a first-line treatment.","evidence":"Limited"},{"condition":"Anxiety disorders","description":"Occasionally used as an adjunct, but not approved for this purpose.","evidence":"Insufficient"}]

Primary treatment for: Neuropathic pain

Also treats: Diabetic neuropathy, Postherpetic neuralgia, Vitamin B12 deficiency, Epilepsy (adjunct), Restless legs syndrome

📋 Drug Information

Generic Name(s)Gabapentin (300mg) + Methylcobalamin (0.5mg)
Brand Namegabarace-m tablet
ManufacturerRace Pharmaceuticals pvt ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Start with a low dose and increase gradually to minimize side effects.
2
Advise patients to take the last dose at bedtime to reduce daytime drowsiness.
3
Monitor renal function regularly, especially in elderly patients.
4
Warn patients not to stop the medicine abruptly to avoid withdrawal symptoms.
5
Ask about alcohol consumption and advise complete avoidance.
6
Assess for suicidal thoughts, especially in patients with a history of depression.
7
Recommend a slow tapering schedule when discontinuing the medicine.
8
Educate patients about the importance of adhering to the prescribed schedule.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning or tingling in feet
This medicine is commonly prescribed for diabetic neuropathy.
Likely Use
✅
Shooting pain after shingles
This medicine is used for postherpetic neuralgia.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionGabapentin is absorbed from the small intestine via a saturable transport mechanism. Bioavailability decreases as the dose increases. Methylcobalamin is absorbed in the ileum with the help of intrinsic factor.
DistributionGabapentin distributes widely in the body but does not bind significantly to plasma proteins. It crosses the blood-brain barrier. Methylcobalamin is transported into tissues and stored in the liver.
Protein BindingGabapentin is less than 3% bound to plasma proteins. Methylcobalamin is approximately 20% bound to plasma proteins.
MetabolismGabapentin is not metabolized in humans and is excreted unchanged. Methylcobalamin is metabolized in the liver to active coenzyme forms.
Half-LifeGabapentin elimination half-life is approximately 5 to 7 hours in patients with normal kidney function. Methylcobalamin half-life is about 6 days.
ExcretionGabapentin is excreted unchanged in the urine. Methylcobalamin is excreted in bile and urine.
BioavailabilityGabapentin bioavailability is approximately 60% at 300 mg dose but decreases with higher doses. Methylcobalamin bioavailability is about 50% when taken orally.
Onset of ActionPain relief may begin within 1 to 2 weeks, but full effect may take 3 to 4 weeks.
Peak Plasma TimeGabapentin reaches peak plasma concentration in 2 to 3 hours. Methylcobalamin peaks in about 6 to 8 hours.
Duration of ActionThe effect of a single dose lasts about 6 to 8 hours, but pain relief is maintained with regular dosing.

How It Works

Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, substance P, and noradrenaline, which are involved in pain signaling. Methylcobalamin is a coenzyme that supports methionine synthase, which is essential for myelin synthesis and nerve cell maintenance. Together, they help reduce abnormal nerve firing and promote nerve repair.

Mechanism Steps

1
Binding to calcium channels: Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels on presynaptic neurons.
2
Reduced neurotransmitter release: This binding decreases calcium influx and reduces the release of pain-related neurotransmitters like glutamate and substance P.
3
Stabilization of nerve membranes: The overall effect is stabilization of hyperexcitable nerve membranes, leading to reduced pain signals.
4
Nerve repair support: Methylcobalamin provides methyl groups for myelin synthesis and supports repair of damaged nerve sheaths.

💡 How to Take gabarace-m tablet

Strength: Each tablet contains Gabapentin 300 mg and Methylcobalamin 0.5 mg.

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Do not crush, chew, or break the tablet.
4Take it at the same time each day to maintain consistent levels.
5If it upsets your stomach, take it with a meal or snack.
6Do not stop taking this medicine suddenly without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, or as directed by your physician. The dose may be gradually increased based on your response and tolerability. For neuropathic pain, the starting dose is often 300 mg of gabapentin once daily, which may be increased to 300 mg twice daily or three times daily. The maximum recommended dose is 3600 mg per day of gabapentin in divided doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced renal function. Start with a low dose and titrate slowly. Monitor for dizziness, drowsiness, and falls. Dose must be individualized by a qualified clinician based on renal function.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance 30-59 mL/min, the dose may be reduced to 200-700 mg twice daily. For creatinine clearance 15-29 mL/min, 200-700 mg once daily. For creatinine clearance <15 mL/min, 100-300 mg once daily. Consult your doctor for precise dosing.
Hepatic ImpairmentNo dose adjustment is needed for hepatic impairment as gabapentin is not metabolized by the liver. However, monitor for side effects.
Maximum Daily DoseThe maximum daily dose of gabapentin is 3600 mg. The maximum daily dose of methylcobalamin is 1500 mcg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and dizziness.
Caffeine
Limit
May increase jitteriness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of gabarace-m tablet

✅ Common Side Effects

Dizziness (Common (10-20%))
Avoid driving or operating machinery until you know how it affects you. If persistent, consult your doctor.
Drowsiness (Common (10-20%))
Take the medicine at bedtime if it makes you sleepy. Avoid alcohol.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, talk to your doctor.
Unsteadiness (Common (5-10%))
Use caution when walking or climbing stairs. Report if it worsens.
Nausea (Uncommon (1-5%))
Take with food to reduce nausea. If it continues, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help if you experience rash, itching, swelling of face or throat, or difficulty breathing.
Suicidal thoughts or behavior (Rare (<0.1%))
Contact your doctor immediately if you have thoughts of harming yourself.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical attention if you develop a painful rash with blisters or peeling skin.
Kidney failure (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor promptly.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bruising or bleeding to your doctor.
Pancreatitis
Seek medical attention if you have severe abdominal pain that radiates to your back.
Rhabdomyolysis
Report muscle pain, weakness, or dark urine immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Morphine Major
Hydrocodone Major
Antacids Moderate
Cimetidine Moderate
Oral contraceptives Moderate
Naproxen Minor
Chlorpromazine Minor
Alcohol Major

🚨 Major Interactions

  • Morphine
  • Hydrocodone

⚡ Moderate Interactions

  • Antacids (aluminum/magnesium)
  • Cimetidine
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol increases the sedative effects of gabapentin and can lead to severe drowsiness, dizziness, and impaired coordination. Avoid alcohol completely while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to gabapentin or methylcobalamin.","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["May cause dizziness and drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not stop this medicine abruptly as it can cause withdrawal symptoms.","Use with caution in elderly patients due to increased risk of falls.","May increase risk of suicidal thoughts; monitor mood closely.","Can cause peripheral edema; report swelling to your doctor.","May impair fertility in some men; discuss with your doctor if planning pregnancy.","Avoid alcohol while taking this medicine.","Inform your doctor if you have kidney disease, as dose adjustment is needed."]

🤱 Lactation Safety

Gabapentin is excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless the benefit outweighs the risk. Methylcobalamin is safe in breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, double vision, slurred speech, and diarrhea. In case of overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases with renal failure.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop suddenly without medical advice, as this can cause withdrawal symptoms such as anxiety, insomnia, and sweating. Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. Inform your doctor if you have kidney problems, as the dose may need adjustment. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep all follow-up appointments and get regular blood tests if advised. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of dizziness, drowsiness, and falls. Dose adjustment is often needed based on renal function. Monitor closely for confusion and unsteadiness.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Gabapentin may harm the fetus. Effective contraception should be used during treatment. Methylcobalamin is generally safe.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine, as it may interact with anesthetic agents and increase sedation. It may also affect pain management after surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may interact with local anesthetics or sedatives used during dental procedures. It may also cause dry mouth, which can affect dental health.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce nerve stress.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice good posture to prevent nerve compression.
💧
Include foods rich in vitamin B12 like eggs, fish, and dairy.
🧘
Get adequate sleep to support nerve health.
🌞
Manage stress through meditation or yoga.

🏋️ Exercise Considerations

Avoid high-impact exercises that may worsen nerve pain. Start slowly and gradually increase activity. If you experience dizziness or unsteadiness, avoid activities that require balance until you know how the medicine affects you.

🥗 Diet Recommendations

Include omega-3 rich foods like flaxseeds and walnuts.
Reduce processed and sugary foods.
Stay well hydrated.
Eat a balanced diet rich in B vitamins.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness and dizziness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also affect concentration, so take breaks if needed. Inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your condition improves, your doctor may gradually reduce the dose. Abrupt discontinuation can cause withdrawal symptoms such as anxiety, insomnia, and sweating.

📅 Long-Term Use Effects

Long-term use of gabapentin may lead to tolerance, dependence, and withdrawal symptoms upon discontinuation. Regular monitoring of kidney function and vitamin B12 levels is advised. Some patients may experience memory problems or difficulty concentrating. Periodic review of the need for continued therapy is recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Acupuncture

May help reduce neuropathic pain in some patients.

Evidence: Moderate
Transcutaneous electrical nerve stimulation (TENS)

May provide symptomatic relief for nerve pain.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor if you are scheduled to receive any live vaccines, as gabapentin may affect immune response in rare cases.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. If you are crossing time zones, adjust your dosing schedule gradually to avoid missed doses. Store it in a cool, dry place away from direct sunlight. Check customs regulations for controlled substances before traveling internationally. Always carry enough supply for the entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with diabetic neuropathy
He had been suffering from burning pain in both feet for over a year. His doctor prescribed this medicine. After 3 weeks, he noticed a significant reduction in pain and improved sleep. He experienced mild dizziness initially, which subsided after a few days. He was advised to avoid alcohol and to take the medicine regularly.
💡 Lesson: Consistent use and patience are key; benefits may take a few weeks to appear.
👤 A 62-year-old woman with postherpetic neuralgia
After a bout of shingles, she developed severe shooting pain in her chest. She was started on this medicine. The pain gradually decreased over a month. She had some drowsiness, so she took the medicine at night. She was monitored for kidney function and did well.
💡 Lesson: Taking the medicine at bedtime can help manage drowsiness, and regular monitoring is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: It may take 1 to 2 weeks to notice improvement, but full effects may take 3 to 4 weeks.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop suddenly. Consult your doctor for a tapering schedule.

Q: Is it safe to take with other painkillers?

A: Consult your doctor before combining with other painkillers, as interactions may occur.

Q: Does it cause weight gain?

A: Weight gain is not a common side effect, but some people may experience increased appetite.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for gabarace-m tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a simple painkiller like paracetamol.
    Fact: This medicine is not a simple painkiller; it works on nerve signals and is specifically for neuropathic pain.
  • Myth: You can stop this medicine as soon as you feel better.
    Fact: Stopping suddenly can cause withdrawal symptoms. Always taper off under medical supervision.
  • Myth: This medicine is addictive.
    Fact: Gabapentin has a low potential for abuse but can cause dependence. It should be used only as prescribed.
  • Myth: It is safe to drink alcohol while taking this medicine.
    Fact: Alcohol increases drowsiness and dizziness and should be avoided.

🔄 Alternative Options

Generic Alternatives

  • Gabapentin 300 mg + Methylcobalamin 0.5 mg tablet (generic)

Brand Alternatives

  • Gabapin 300 mg tablet
  • Gabantin 300 mg tablet
  • Nurokind-G 300 mg tablet
  • Maxgalin 300 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Alfagaba 300mg","composition":"Gabapentin 300mg + Methylcobalamin 0.5mg","uses":"Neuropathic pain","onset":"1-2 weeks"},{"medicine":"Pregabalin + Methylcobalamin","composition":"Pregabalin 75mg + Methylcobalamin 750mcg","uses":"Neuropathic pain","onset":"1-2 weeks"},{"medicine":"Duloxetine","composition":"Duloxetine 30mg","uses":"Neuropathic pain, depression","onset":"2-4 weeks"}]

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