fubac cream - Beclometasone (0.025% w/w) + Gentamicin (0.1% w/w) medicine

Derminol Cream: Complete Guide to Uses, Side Effects, and Safety

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🏭 Karnataka Antibiotics & Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: rash, itching, swelling, dizziness, trouble breathing.
  • Signs of kidney damage: decreased urine output, swelling in legs or ankles.
  • Signs of hearing loss: ringing in ears, difficulty hearing.
  • Severe skin reactions: blistering, peeling, or open sores.
  • Signs of systemic infection: fever, chills, rapid heartbeat.
  • No improvement after 1 week of use.
  • New or worsening skin infection.

If experiencing severe symptoms, call emergency services immediately.

What is fubac cream used for?

This medicine is a topical cream containing beclometasone (a steroid) and gentamicin (an antibiotic). It is used to treat inflamed skin conditions that are infected or at risk of infection. Apply a thin layer to the affected area as directed by your doctor, usually 1-2 times daily. Do not use for more than 2 weeks without medical advice.

  • Generic Name: Beclometasone (0.025% w/w) + Gentamicin (0.1% w/w)
  • Manufacturer: Karnataka Antibiotics & Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 fubac cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें बेक्लोमेथासोन (एक स्टेरॉयड) और जेंटामाइसिन (एक एंटीबायोटिक) शामिल हैं। इसका उपयोग त्वचा की सूजन और संक्रमण वाली स्थितियों जैसे संक्रमित एक्जिमा, डर्मेटाइटिस, कीड़े के काटने आदि के इलाज के लिए किया जाता है। यह सूजन, खुजली और लालिमा को कम करता है और बैक्टीरिया को मारता है। इसे डॉक्टर के निर्देशानुसार प्रभावित हिस्से पर पतली परत में लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, या लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं। कभी-कभी एलर्जी भी हो सकती है। अगर कोई गंभीर प्रतिक्रिया हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस क्रीम को केवल बाहरी उपयोग के लिए ही लगाएं। आंखों, नाक, मुंह और जननांगों पर न लगाएं। डॉक्टर की सलाह के बिना चेहरे, बगल या जांघों पर न लगाएं। लंबे समय तक इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों में डॉक्टर की सलाह के बिना इस्तेमाल न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 fubac cream Uses & Benefits

[{"condition":"Infected eczema","description":"Used to reduce inflammation and treat bacterial infection in eczema lesions.","evidence":"Well-established"},{"condition":"Infected dermatitis","description":"Helps control inflammation and infection in contact or atopic dermatitis.","evidence":"Well-established"},{"condition":"Infected insect bites","description":"Reduces swelling, itching, and prevents infection from scratching.","evidence":"Commonly used"},{"condition":"Infected minor skin injuries","description":"Used on small cuts, scrapes, or abrasions that show signs of infection.","evidence":"Commonly used"}]

Off-label uses: [{"condition":"Psoriasis with secondary infection","description":"Sometimes used short-term to manage infected psoriatic plaques.","evidence":"Limited"},{"condition":"Seborrheic dermatitis with infection","description":"May be used when bacterial infection complicates seborrheic dermatitis.","evidence":"Limited"}]

Primary treatment for: Infected dermatitis

Also treats: Infected eczema, Infected insect bites, Infected minor skin injuries

📋 Drug Information

Generic Name(s)Beclometasone (0.025% w/w) + Gentamicin (0.1% w/w)
Brand Namefubac cream
ManufacturerKarnataka Antibiotics & Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore below 25°C in a cool, dry place. Do not freeze. Keep the tube tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer only to the affected area and avoid normal skin.
2
Do not use for more than 2 weeks without consulting your doctor.
3
Wash your hands before and after application to prevent spreading infection.
4
Avoid using on the face, groin, or underarms unless specifically prescribed.
5
If symptoms do not improve within 1 week, consult your doctor.
6
Do not cover the treated area with tight bandages unless instructed.
7
Report any signs of skin thinning, stretch marks, or new infections.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Infected eczema
This medicine is commonly prescribed for this.
Likely Use
✅
Infected insect bite
This medicine can be used for infected insect bites.
Likely Use
❌
Acne
This medicine is not for acne and may worsen it.
Not Primary
❌
Fungal infection
This medicine is not effective against fungal infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBeclometasone dipropionate is absorbed through intact skin, especially when applied to inflamed or damaged skin or under occlusive dressings. Gentamicin is poorly absorbed through intact skin but can be absorbed through broken skin or wounds.
DistributionNot established from the available information.
Protein BindingBeclometasone: about 87% bound to plasma proteins. Gentamicin: less than 30% bound to plasma proteins.
MetabolismBeclometasone is metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4. Gentamicin is not metabolized and is excreted unchanged.
Half-LifeBeclometasone: approximately 15 hours (for the active metabolite beclometasone-17-monopropionate). Gentamicin: 2 to 3 hours in adults with normal renal function.
ExcretionBeclometasone metabolites are excreted mainly in bile and urine. Gentamicin is excreted unchanged by the kidneys via glomerular filtration.
BioavailabilityNot established from the available information for topical application.
Onset of ActionAnti-inflammatory effects may begin within hours to days; antibacterial effects depend on bacterial susceptibility and may take 24 to 48 hours to show improvement.
Peak Plasma TimeNot established from the available information for topical application.
Duration of ActionAnti-inflammatory effect lasts several hours after application; antibacterial effect persists as long as adequate concentrations are maintained at the site.

How It Works

This medicine combines a corticosteroid and an aminoglycoside antibiotic. Beclometasone binds to glucocorticoid receptors inside skin cells, leading to reduced production of inflammatory chemicals like prostaglandins and leukotrienes. This decreases redness, swelling, itching, and pain. Gentamicin works by binding to bacterial ribosomal subunits, causing misreading of genetic code and blocking protein synthesis, which kills susceptible bacteria. Together, they reduce inflammation and treat bacterial infection.

Mechanism Steps

1
Beclometasone binds to glucocorticoid receptor: Beclometasone enters skin cells and binds to cytoplasmic glucocorticoid receptors.
2
Reduction of inflammatory mediators: The receptor-ligand complex moves into the nucleus and inhibits transcription of pro-inflammatory genes, reducing cytokines and enzymes like COX-2.
3
Gentamicin binds to bacterial ribosome: Gentamicin penetrates bacterial cells and binds irreversibly to the 30S ribosomal subunit.
4
Inhibition of protein synthesis: This binding causes misreading of mRNA and blocks protein synthesis, leading to bacterial cell death.

💡 How to Take fubac cream

Strength: Cream containing beclometasone 0.025% w/w and gentamicin 0.1% w/w.

1Wash your hands thoroughly before and after applying the cream.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected area.
4Rub it in gently until it disappears.
5Do not cover the area with a bandage unless instructed.
6Avoid contact with eyes, nose, and mouth.
7Use exactly as prescribed by your doctor.

Dosage Information

Adult DosageApply a thin layer to the affected area 1 to 2 times daily, or as directed by your doctor. The frequency and duration depend on the condition being treated and your response. Do not use for more than 2 weeks without medical advice. Dose must be individualized by a qualified clinician based on indication, age, and severity of the condition.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. Use in children should be limited to the lowest effective dose for the shortest duration.
Elderly DosageNo specific dosage adjustments are established for elderly patients. Use with caution and monitor for skin thinning and systemic effects.
Renal ImpairmentNo specific dosage adjustments are established for topical use. Use with caution in patients with renal impairment due to potential systemic absorption of gentamicin.
Hepatic ImpairmentNo specific dosage adjustments are established for topical use. Use with caution in patients with hepatic impairment.
Maximum Daily DoseNot established from the available information. Do not exceed the prescribed frequency and duration.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of fubac cream

✅ Common Side Effects

Application site burning (Common (1-10%))
Usually resolves with continued use. If severe, stop and consult doctor.
Application site itching (Common (1-10%))
Avoid scratching. Consult doctor if persistent.
Skin redness (Common (1-10%))
May be due to the condition or cream. Consult doctor if worsens.
Dryness or peeling (Common (1-10%))
Use a moisturizer if recommended by doctor.

🚨 Serious Side Effects

Skin thinning (atrophy) (Uncommon (0.1-1%))
Stop use and consult doctor. Avoid long-term use without supervision.
Stretch marks (striae) (Uncommon (0.1-1%))
Stop use and consult doctor. Usually irreversible.
Allergic contact dermatitis (Rare (<0.1%))
Stop use and seek medical advice. May need allergy testing.
Nephrotoxicity (kidney damage) from systemic absorption (Rare (<0.1%))
Seek immediate medical attention if decreased urine output or swelling occurs.
Ototoxicity (hearing loss) from systemic absorption (Rare (<0.1%))
Seek immediate medical attention if hearing changes or ringing in ears occurs.

⚠️ Rare Side Effects

HPA axis suppression
Consult doctor if you experience fatigue, weakness, or weight loss.
Cushing's syndrome
Seek medical advice if you notice rapid weight gain, moon face, or easy bruising.
Secondary infection
Consult doctor if new infection signs appear.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other aminoglycosides Major
Loop diuretics Major
CYP3A4 inhibitors Moderate
Other topical corticosteroids Moderate

🚨 Major Interactions

  • Other aminoglycosides (e.g., neomycin, streptomycin)
  • Loop diuretics (e.g., furosemide)

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • Other topical corticosteroids

🍷 Alcohol Interaction

No known interaction between this topical medicine and alcohol. However, alcohol may worsen certain skin conditions. Consult your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to beclometasone, gentamicin, or any component of the cream","Untreated bacterial, viral, or fungal skin infections without appropriate therapy","Acne vulgaris, rosacea, and perioral dermatitis","Use on the face, groin, or axillae unless directed by a doctor","Use in children under 1 year of age"]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes, mucous membranes, and broken skin.","Do not use under occlusive dressings unless instructed.","Prolonged use can cause skin thinning, stretch marks, and systemic effects.","Gentamicin may cause allergic contact dermatitis.","Use in pregnancy and breastfeeding only if clearly needed.","Keep out of reach of children.","Do not use for more than 2 weeks without medical advice."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Overdose from topical application is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and diarrhea. In case of excessive topical use, wash the area with water and consult a doctor.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Do not apply to the eyes, face, groin, or underarms unless directed by a doctor. Do not cover the treated area with airtight dressings unless instructed. Wash your hands before and after applying the cream. Avoid contact with the eyes, nose, and mouth. Do not use this medicine for longer than prescribed, as prolonged use can cause skin thinning and other side effects. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use on children under 1 year of age unless prescribed by a doctor. Keep out of reach of children. Do not use if the tube is damaged or if the cream has changed color or consistency.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to skin thinning and systemic effects. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy or if you become pregnant while using this medicine. Use only if clearly needed.

🏥 Post-Surgery Considerations

Consult your surgeon before using this cream on or near surgical wounds. It may interfere with wound healing or mask infection.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid scratching the affected area to prevent worsening infection.
😴
Wear loose, breathable clothing over the treated area.
💧
Avoid sharing towels or personal items to prevent spreading infection.
🧘
Follow a healthy diet to support skin healing.
🌞
Manage stress as it can worsen skin conditions.

🏋️ Exercise Considerations

No specific exercise restrictions. However, avoid activities that cause excessive sweating or friction on the treated area until healed.

🥗 Diet Recommendations

Include foods rich in vitamin C and zinc to support skin healing.
Stay well hydrated.
Avoid excessive sugar and processed foods that may worsen inflammation.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or allergic reaction, avoid these activities.

🛑 When to Stop This Medicine

Stop using this medicine when the infection and inflammation have resolved, or as directed by your doctor. Do not use for more than 2 weeks without medical advice. If you experience severe side effects, stop and consult your doctor immediately.

📅 Long-Term Use Effects

Prolonged use of this medicine can lead to skin thinning, stretch marks, and increased hair growth. Systemic absorption of gentamicin can rarely cause kidney damage or hearing loss. Regular monitoring by a doctor is advised if long-term use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical calcineurin inhibitors

Non-steroidal anti-inflammatory creams for eczema, but they do not treat bacterial infection.

Evidence: Well-established
Oral antibiotics

For more severe or widespread skin infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. However, consult your doctor before vaccination if you have an active skin infection.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription. Store at room temperature, away from direct sunlight and moisture. If traveling to a different climate, keep the tube tightly closed. No time zone adjustments are needed for topical use. Declare it at customs if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with infected eczema on her hands
She was prescribed this cream to apply twice daily. After 5 days, her itching and redness reduced significantly, and the infection cleared. She was advised to stop after 10 days and use a moisturizer.
💡 Lesson: Short-term use as prescribed is effective and safe. Do not extend use without medical advice.
👤 A 60-year-old man with an infected insect bite on his leg
He applied the cream for 3 days and noticed improvement. However, he continued using it for 3 weeks and developed skin thinning. He was advised to stop and use a milder cream.
💡 Lesson: Prolonged use can cause skin thinning. Always follow the prescribed duration.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice improvement in itching and redness within a few days. The antibacterial effect may take 24-48 hours. If no improvement after 1 week, consult your doctor.

Q: Can I use this cream on my face?

A: No, unless specifically prescribed by your doctor. It can cause skin thinning and other side effects on the face.

Q: Is it safe during pregnancy?

A: Consult your doctor before use. Topical corticosteroids should be used only if clearly needed.

Q: What if I miss a dose?

A: Apply as soon as you remember. If it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this cream on my face?
  • How long can I use this cream?
  • Is it safe for children?
  • Can I use it during pregnancy?
  • What if I miss a dose?
  • Does it interact with other medicines?

🔄 Substitutes for fubac cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This cream can be used for any skin rash.
    Fact: It is only for specific infected inflammatory skin conditions. Using it for other rashes can worsen them.
  • Myth: More cream means faster healing.
    Fact: Applying more than prescribed increases risk of side effects without added benefit.
  • Myth: It is safe to use for months.
    Fact: Prolonged use can cause skin thinning and other serious effects. Use only as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Beclometasone + Gentamicin cream (generic)

Brand Alternatives

  • Derminol cream

📊 Comparison with Similar Medicines

[{"medicine":"Beclometasone + Gentamicin","strength":"0.025% + 0.1%","potency":"Moderate","use":"Infected dermatitis"},{"medicine":"Betamethasone + Gentamicin","strength":"0.05% + 0.1%","potency":"Potent","use":"Infected dermatitis"},{"medicine":"Hydrocortisone + Gentamicin","strength":"1% + 0.1%","potency":"Mild","use":"Mild infected dermatitis"}]

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