Sinarest Linctus: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swallowing
- Swelling of face, lips, or throat
- Severe dizziness or fainting
- Irregular heartbeat or palpitations
- Hallucinations or confusion
- Seizures
- Blood in cough or vomit
If experiencing severe symptoms, call emergency services immediately.
What is evodex dmr syrup used for?
This medicine is a combination of chlorpheniramine (an antihistamine) and dextromethorphan (a cough suppressant) used to treat dry cough and allergic symptoms. It works by blocking histamine and suppressing the cough reflex. It may cause drowsiness, so avoid driving. Do not use for more than 7 days without consulting a doctor.
- Generic Name: Chlorpheniramine Maleate (2mg) + Dextromethorphan Hydrobromide (10mg)
- Manufacturer: Casca Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 evodex dmr syrup के बारे में (Hindi Summary)
उपयोग: यह दवा सूखी खांसी और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना और आंखों में पानी आना के इलाज के लिए उपयोग की जाती है। यह खांसी को दबाने और एलर्जी को कम करने में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, जी मिचलाना और धुंधली दृष्टि शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, मतिभ्रम और अनियमित दिल की धड़कन हो सकती है।
सुरक्षा सलाह: दवा की खुराक से अधिक न लें। शराब और अन्य नींद लाने वाली दवाओं से बचें। गाड़ी चलाने या मशीन चलाने से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 evodex dmr syrup Uses & Benefits
[{"condition":"Dry cough","description":"Suppresses non-productive cough by acting on the cough center in the brain.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, and watery eyes due to allergic reactions.","evidence":"Well-established"},{"condition":"Common cold symptoms","description":"Provides symptomatic relief from cough and nasal congestion associated with colds.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Dry cough and allergic rhinitis
Also treats: Common cold, Allergic conjunctivitis, Sneezing
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate (2mg) + Dextromethorphan Hydrobromide (10mg) |
| Brand Name | evodex dmr syrup |
| Manufacturer | Casca Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing allergic symptoms. Dextromethorphan Hydrobromide is a centrally acting cough suppressant that acts on the cough center in the medulla oblongata to raise the threshold for coughing.
Mechanism Steps
💡 How to Take evodex dmr syrup
Strength: Each 5 ml contains Chlorpheniramine Maleate 2mg and Dextromethorphan Hydrobromide 10mg.
Dosage Information
| Adult Dosage | The usual adult dose is 5-10 ml (1-2 teaspoons) every 4-6 hours as needed, not to exceed 60 ml in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in renal impairment. Dose adjustment may be necessary. Consult a clinician. |
| Hepatic Impairment | Use with caution in hepatic impairment. Dose adjustment may be necessary. Consult a clinician. |
| Maximum Daily Dose | 60 ml in 24 hours for adults. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of evodex dmr syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| CNS depressants | Major | |
| Anticholinergics | Moderate | |
| CYP2D6 inhibitors | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, benztropine)
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
🍷 Alcohol Interaction
Alcohol increases the sedative effects of chlorpheniramine and dextromethorphan, leading to excessive drowsiness, dizziness, and impaired judgment. Avoid alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, dextromethorphan, or any component of the formulation.","Concurrent use with MAO inhibitors or within 14 days of stopping MAO inhibitor therapy.","Chronic cough associated with asthma, COPD, or smoking.","Productive cough with excessive mucus.","Children under 12 years of age (unless directed by a physician)."]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, urinary retention, or prostatic hypertrophy.","Do not use for persistent or chronic cough unless directed by a doctor.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever, rash, or persistent headache."]
🤱 Lactation Safety
Chlorpheniramine and dextromethorphan may pass into breast milk. Consult your doctor before use if you are breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, dizziness, hallucinations, rapid heartbeat, and seizures. Seek emergency medical attention immediately. Treatment is supportive and symptomatic. Gastric lavage may be considered if within 1-2 hours of ingestion. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Do not exceed the recommended dose. Avoid alcohol and other central nervous system depressants while taking this medicine. Do not drive or operate heavy machinery until you know how this medicine affects you. Consult your doctor before use if you are pregnant, breastfeeding, or have a chronic medical condition such as asthma, glaucoma, or difficulty urinating. Keep out of reach of children. Do not use for persistent or chronic cough unless directed by a doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects. Use with caution and consider lower doses. Monitor for confusion, dizziness, and urinary retention.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are pregnant or planning to become pregnant. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with anesthetics and other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine due to potential drowsiness and dizziness. Light activities are fine if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also reduce your alertness at work.
🛑 When to Stop This Medicine
Stop taking this medicine if your cough persists beyond 7 days, or if you experience severe side effects. Consult your doctor before stopping if you have been on it for a prolonged period.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance, dependence, and increased risk of side effects. Consult your doctor if symptoms persist beyond 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can soothe dry cough and throat irritation.
Evidence: Well-establishedHelps relieve nasal congestion and cough.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, consult your doctor before vaccination if you are unwell.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from light. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying liquid medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 15-30 minutes after oral administration.
A: Do not take with other cough and cold medicines without consulting your doctor, as it may lead to overdose.
A: Pediatric dosing is not established. Consult a pediatrician before giving to children.
🤔 Common Patient Concerns
🔄 Substitutes for evodex dmr syrup
View AllAlternative brands with exact same active ingredient:
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flugone suspensionLA Grande Pvt Ltd ₹28.59 59.3% CHEAPER
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kuffery-dx dry syrupZeelab Pharmacy Pvt Ltd ₹30.00 57.3% CHEAPER
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atminic dca tabletAtopic Laboratories ₹30.94 56% CHEAPER
-
jtus-c soft gelatin capsuleJunifer Pharmaceuticals ₹32.81 53.3% CHEAPER
-
Stopper P SyrupZenon Healthcare Ltd ₹33.00 53.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure a cold.
Fact: It only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take with alcohol.
Fact: Alcohol increases drowsiness and other side effects; avoid combining.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine + Dextromethorphan oral liquid