etized plus tablet - Etizolam (0.5mg) + Propranolol (20mg) medicine

Etilaam Pro 20 Tablet: Complete Medicine Guide

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🏭 Mediez Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
🤰 Pregnancy Category This medicine is not recommended during pregnancy unless clearly needed. Both Etizolam and Propranolol may pose risks to the fetus. Etizolam may cause sedation and withdrawal symptoms in the newborn if used near term. Propranolol may cause fetal bradycardia, growth restriction, and hypoglycemia. Consult your doctor immediately if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for the combination in anxiety; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness, fainting, or slow heartbeat
  • Difficulty breathing, wheezing, or chest tightness
  • Swelling of face, lips, tongue, or throat
  • Confusion, hallucinations, or extreme drowsiness
  • Unusual bruising or bleeding
  • Yellowing of skin or eyes (jaundice)
  • Seizures or tremors

If experiencing severe symptoms, call emergency services immediately.

What is etized plus tablet used for?

This medicine is a combination of Etizolam and Propranolol used for short-term treatment of anxiety. Etizolam calms the mind, while Propranolol controls physical symptoms like fast heartbeat and trembling. It is a prescription drug and should be taken exactly as directed by a doctor.

  • Generic Name: Etizolam (0.5mg) + Propranolol (20mg)
  • Manufacturer: Mediez Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 etized plus tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एटिजोलम और प्रोप्रानोलोल का संयोजन है, जिसका उपयोग चिंता विकारों के अल्पकालिक उपचार के लिए किया जाता है। एटिजोलम मन को शांत करता है और प्रोप्रानोलोल दिल की धड़कन और कंपन जैसे शारीरिक लक्षणों को नियंत्रित करता है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर के निर्देशानुसार ही लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, थकान, हाथ-पैर ठंडे होना और हृदय गति धीमी होना शामिल है। कुछ लोगों को मतली, मुँह सूखना या धुंधली दृष्टि भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, बेहोशी या तेज धड़कन हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अपने आप बंद न करें, क्योंकि इससे withdrawal symptoms हो सकते हैं। दवा लेते समय शराब न पिएं। गाड़ी चलाने या मशीन चलाने से बचें जब तक कि आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 etized plus tablet Uses & Benefits

[{"condition":"Anxiety disorders with prominent physical symptoms","description":"This combination helps reduce both the psychological worry and the physical symptoms of anxiety such as palpitations, tremors, and sweating.","evidence":"Moderate"},{"condition":"Short-term management of acute stress reactions","description":"May be used for a brief period to manage severe stress-related symptoms under medical supervision.","evidence":"Limited"},{"condition":"Anxiety associated with cardiovascular symptoms","description":"Propranolol component helps control heart rate and blood pressure, which can be beneficial when anxiety causes cardiovascular overactivity.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Performance anxiety","description":"Sometimes prescribed off-label for situational anxiety such as public speaking or stage fright, but only under medical guidance.","evidence":"Limited"},{"condition":"Essential tremor with anxiety","description":"Propranolol is used for essential tremor, and the combination may help when anxiety coexists, but this is not a standard approved use.","evidence":"Limited"}]

Primary treatment for: Anxiety disorders

Also treats: Stress-related disorders, Cardiovascular symptoms of anxiety, Essential tremor with anxiety

📋 Drug Information

Generic Name(s)Etizolam (0.5mg) + Propranolol (20mg)
Brand Nameetized plus tablet
ManufacturerMediez Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Keep away from moisture, heat, and direct sunlight. Store in the original container to protect from light.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed. Do not increase or decrease the dose without consulting your doctor.
2
Avoid driving or operating heavy machinery until you know how this medicine affects your alertness.
3
Do not stop this medicine abruptly; your doctor will gradually reduce the dose to prevent withdrawal symptoms.
4
Inform your doctor if you have asthma, heart problems, diabetes, or liver/kidney disease before starting this medicine.
5
Avoid alcohol and other sedatives while taking this medicine to prevent excessive drowsiness and low blood pressure.
6
Keep all follow-up appointments so your doctor can monitor your response and adjust the dose if needed.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Anxiety with palpitations
This medicine is commonly prescribed for this.
Likely Use
✅
Tremors
Propranolol component helps reduce tremors.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not typically used for headache relief.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionEtizolam is rapidly absorbed from the gastrointestinal tract after oral administration. Propranolol is also well absorbed but undergoes significant first-pass metabolism. Food may affect the absorption of Propranolol, so it is best taken consistently with or without food as advised by your doctor.
DistributionEtizolam is highly lipophilic and distributes widely into body tissues, including the brain. Propranolol is also highly lipophilic and crosses the blood-brain barrier. Both drugs have large volumes of distribution.
Protein BindingEtizolam is approximately 93% bound to plasma proteins. Propranolol is about 90% bound to plasma proteins, primarily albumin.
MetabolismEtizolam is metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4 and CYP2C19. Propranolol undergoes extensive first-pass metabolism in the liver, mainly via CYP2D6 and CYP1A2.
Half-LifeThe elimination half-life of Etizolam is approximately 6 hours, while that of Propranolol ranges from 3 to 6 hours. However, these values can vary based on individual factors.
ExcretionEtizolam and its metabolites are primarily excreted in the urine. Propranolol metabolites are also excreted in the urine, with small amounts in feces.
BioavailabilityThe oral bioavailability of Etizolam is approximately 90%. Propranolol has a variable oral bioavailability of about 30% due to first-pass metabolism.
Onset of ActionEtizolam typically begins to act within 30 to 60 minutes after oral administration. Propranolol's effects on heart rate can be noticed within 1 to 2 hours.
Peak Plasma TimePeak plasma concentrations of Etizolam are reached in about 1 to 2 hours. Propranolol peaks in about 1 to 2 hours after oral administration.
Duration of ActionThe anxiolytic effect of Etizolam lasts about 6 to 8 hours. Propranolol's effect on heart rate lasts about 6 to 12 hours, depending on the dose and individual factors.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Etizolam enhances the inhibitory neurotransmitter GABA at GABA-A receptors, leading to sedation, anxiety relief, and muscle relaxation. Propranolol blocks beta-adrenergic receptors, reducing the physical manifestations of anxiety such as rapid heart rate, tremors, and sweating. Together, they address both the central and peripheral components of anxiety.

Mechanism Steps

1
Etizolam binds to GABA-A receptors: Etizolam binds to the benzodiazepine site on GABA-A receptors, enhancing the inhibitory effect of GABA and reducing neuronal excitability.
2
Enhanced chloride channel opening: This binding increases the frequency of chloride channel opening, leading to hyperpolarization of neurons and a calming effect.
3
Propranolol blocks beta-adrenergic receptors: Propranolol competitively blocks beta-1 and beta-2 adrenergic receptors, reducing the effects of adrenaline and noradrenaline.
4
Reduced sympathetic outflow effects: This blockade decreases heart rate, contractility, and renin secretion, which lowers blood pressure and reduces physical anxiety symptoms like tremors and palpitations.

💡 How to Take etized plus tablet

Strength: Each tablet contains Etizolam 0.5 mg and Propranolol 20 mg.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole. Do not crush, chew, or break it.
3Take it with or without food, but be consistent.
4If it upsets your stomach, take it with a meal or snack.
5Follow your doctor's instructions exactly regarding dose and timing.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once or twice daily, or as directed by your doctor. The dose depends on the condition being treated, your response to therapy, and your kidney and liver function. Do not adjust the dose without consulting your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Regular monitoring for sedation, falls, and cognitive impairment is recommended. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with renal impairment, dose reduction may be necessary. Monitor renal function and adjust dose as advised by your doctor. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with hepatic impairment, the clearance of both drugs may be reduced. Use with caution and consider dose reduction. Regular monitoring of liver function is advised. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum daily dose should not exceed what is prescribed by your doctor. Typically, the maximum recommended dose is 2 tablets per day, but this may vary based on individual factors. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Alcohol
Avoid
Increases sedation and risk of low blood pressure.
Grapefruit juice
Avoid
May increase drug levels by affecting liver enzymes.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of etized plus tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dizziness (Common (5-15%))
Rise slowly from sitting or lying position. Stay hydrated.
Fatigue (Common (5-10%))
Get adequate rest. If severe, consult your doctor.
Cold extremities (Common (5-10%))
Keep hands and feet warm. Report if severe or painful.
Nausea (Uncommon (1-5%))
Take with food to reduce stomach upset.

🚨 Serious Side Effects

Severe bradycardia (slow heart rate) (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or unusual weakness.
Bronchospasm (Rare (<0.1%))
Seek emergency care if you develop difficulty breathing, wheezing, or chest tightness.
Severe hypotension (Rare (<0.1%))
Lie down and seek medical help if you feel faint or have very low blood pressure.
Allergic reactions (Rare (<0.1%))
Seek emergency care if you notice rash, swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Hallucinations
Contact your doctor immediately if you experience hallucinations.
Blood dyscrasias
Report unusual bruising, bleeding, or infections to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Verapamil Major
Ketoconazole Major
Opioids Moderate
Alcohol Moderate
Insulin Moderate
NSAIDs Moderate
Antacids Minor
Thyroid hormones Minor
Cimetidine Moderate

🚨 Major Interactions

  • MAO inhibitors
  • Calcium channel blockers (e.g., verapamil, diltiazem)
  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)

⚡ Moderate Interactions

  • CNS depressants (e.g., opioids, alcohol, barbiturates)
  • Antidiabetic drugs
  • NSAIDs

🍷 Alcohol Interaction

Alcohol should be strictly avoided while taking this medicine. It can intensify the sedative effects of Etizolam and the blood pressure-lowering effect of Propranolol, leading to dangerous drowsiness, dizziness, and fainting. It also increases the risk of respiratory depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Etizolam, Propranolol, or any component of the formulation","Severe bradycardia, heart block greater than first degree, or cardiogenic shock","Decompensated heart failure","Asthma or severe chronic obstructive pulmonary disease","Pheochromocytoma (unless alpha-blockade is established first)","Severe liver disease","Myasthenia gravis","Pregnancy and breastfeeding (unless clearly needed)"]

⚠️ Warnings & Precautions

["This medicine can cause drowsiness and dizziness. Avoid driving or operating machinery until you know how it affects you.","Do not stop this medicine abruptly, as it can cause withdrawal symptoms such as anxiety, insomnia, and tremors.","Use with caution in elderly patients due to increased risk of falls, confusion, and cognitive impairment.","Propranolol may mask the symptoms of hypoglycemia in diabetic patients. Monitor blood sugar regularly.","Avoid alcohol and other CNS depressants while taking this medicine.","Inform your doctor if you have a history of asthma, heart disease, diabetes, or thyroid disorders.","This medicine may cause dependence and should be used for the shortest duration possible."]

🤱 Lactation Safety

Both Etizolam and Propranolol pass into breast milk. Etizolam may cause sedation in the nursing infant, and Propranolol may accumulate in breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor. If breastfeeding is essential, monitor the infant for drowsiness, poor feeding, or slow heart rate.

💊 Overdose Management

Overdose of this medicine can cause severe drowsiness, confusion, slow heart rate, low blood pressure, difficulty breathing, and loss of consciousness. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include gastric lavage, activated charcoal, intravenous fluids, and medications to support heart rate and blood pressure. Flumazenil may be used cautiously for Etizolam overdose, but it can precipitate seizures in dependent patients. Propranolol overdose may require glucagon, atropine, or pacemaker insertion.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose on your own. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Do not consume alcohol while taking this medicine because it can intensify sedation and dangerously lower blood pressure. Inform your doctor if you have a history of asthma, heart problems, diabetes, liver disease, or kidney disease. Do not stop this medicine suddenly, especially if you have been taking it for more than a few weeks, as this can cause withdrawal symptoms. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Regular follow-up with your doctor is important to monitor your response and adjust the dose if needed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and cardiovascular effects of this medicine. They are at higher risk of falls, confusion, and cognitive impairment. Start with a lower dose and monitor closely. Regular review of the need for continued therapy is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Both Etizolam and Propranolol may harm the developing fetus. Your doctor may switch you to a safer alternative or adjust the treatment plan.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with anesthetic agents and affect heart rate and blood pressure during and after surgery. Your doctor may advise you to stop the medicine temporarily before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with local anesthetics containing epinephrine and affect heart rate and blood pressure. Your dentist may take precautions or adjust the anesthetic used.

💚 Lifestyle Tips for Better Results

🏃
Practice relaxation techniques such as deep breathing and meditation.
🥗
Maintain a regular sleep schedule.
😴
Engage in regular physical activity as advised by your doctor.
💧
Avoid caffeine and other stimulants that can worsen anxiety.
🧘
Stay connected with friends and family for emotional support.
🌞
Keep a symptom diary to track your progress and share with your doctor.

🏋️ Exercise Considerations

This medicine can cause dizziness and slow heart rate, which may affect your exercise capacity. Avoid strenuous exercise until you know how the medicine affects you. Stay hydrated and avoid overheating. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit caffeine and alcohol intake.
Include omega-3 fatty acids from fish or flaxseed.
Stay well hydrated throughout the day.
Avoid skipping meals to prevent dizziness.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves safety-sensitive tasks.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Your doctor will gradually reduce the dose to prevent withdrawal symptoms. If you experience severe side effects or allergic reactions, seek immediate medical attention.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to tolerance, dependence, and withdrawal symptoms. Etizolam carries a significant risk of dependence, and Propranolol may cause reduced heart rate and blood pressure over time. Regular monitoring and periodic evaluation by your doctor are essential. The medicine should be used for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cognitive behavioral therapy (CBT)

A psychological therapy that helps manage anxiety without medication.

Evidence: Well-established
Mindfulness and meditation

Techniques to reduce stress and anxiety.

Evidence: Moderate
Regular exercise

Physical activity can reduce anxiety symptoms.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations regarding controlled substances before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with generalized anxiety disorder
She was prescribed this medicine for severe anxiety with palpitations. After starting treatment, she noticed significant reduction in her anxiety and physical symptoms within a week. She was advised to take it with food to avoid stomach upset and to avoid driving until she knew how it affected her. She attended regular follow-ups, and her doctor gradually tapered the dose after three months.
💡 Lesson: This medicine can be effective for short-term anxiety management when taken as prescribed and with regular monitoring.
👤 A 50-year-old man with anxiety and hypertension
He was started on this medicine for anxiety and mild hypertension. His blood pressure improved, but he experienced drowsiness initially. His doctor advised him to take the dose at bedtime and to avoid alcohol. Over time, his body adjusted, and the drowsiness decreased. He was monitored for heart rate and blood pressure regularly.
💡 Lesson: Dose timing and regular monitoring help manage side effects and improve tolerability.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Etizolam starts working within 30 to 60 minutes, while Propranolol's effects on heart rate can be noticed within 1 to 2 hours.

Q: Can I take this medicine every day?

A: This medicine is usually prescribed for short-term use. Long-term use should be under strict medical supervision due to the risk of dependence.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe to drive while taking this medicine?

A: This medicine can cause drowsiness and dizziness. Avoid driving or operating machinery until you know how it affects you.

Q: Can I stop this medicine suddenly?

A: No, do not stop this medicine abruptly as it can cause withdrawal symptoms. Consult your doctor for a gradual tapering plan.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for etized plus tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe for long-term use.
    Fact: This medicine is meant for short-term use only. Prolonged use can lead to dependence and withdrawal symptoms.
  • Myth: I can stop this medicine whenever I want.
    Fact: Abrupt discontinuation can cause withdrawal symptoms. Always consult your doctor before stopping.
  • Myth: It is safe to drink alcohol while taking this medicine.
    Fact: Alcohol increases the sedative and blood pressure-lowering effects, which can be dangerous.

🔄 Alternative Options

Generic Alternatives

  • Etizolam + Propranolol combination generics may be available. Consult your pharmacist.

Brand Alternatives

  • Etilaam Pro 20 Tablet is a brand of Intas Pharmaceuticals Ltd. Other brands may exist. Consult your doctor or pharmacist for alternatives.

📊 Comparison with Similar Medicines

[{"medicine":"Etizolam alone","difference":"Lacks Propranolol; does not control physical symptoms like palpitations."},{"medicine":"Propranolol alone","difference":"Lacks Etizolam; does not provide rapid anxiolytic effect."},{"medicine":"Alprazolam","difference":"Another benzodiazepine; may have different onset and duration."}]

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