Esocard 100mg Injection (esmolol): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Difficulty breathing or wheezing
- Chest pain or tightness
- Very slow heart rate (less than 50 beats per minute)
- Swelling of face, lips, or throat
- Confusion or hallucinations
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is esmocard 100mg injection used for?
This medicine is an intravenous beta-blocker used in hospitals to rapidly control heart rate and blood pressure in conditions like supraventricular tachycardia and during surgery. It works within minutes and wears off quickly.
- Generic Name: Esmolol (100mg)
- Manufacturer: Troikaa Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 esmocard 100mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एस्मोलोल 100 मिलीग्राम इंजेक्शन है, जिसका उपयोग अस्पताल में डॉक्टर की देखरेख में दिल की धड़कन को तेजी से नियंत्रित करने और रक्तचाप को कम करने के लिए किया जाता है। यह सुपरवेंट्रिकुलर टैचीकार्डिया, एट्रियल फिब्रिलेशन, और सर्जरी के दौरान होने वाली तेज धड़कन और उच्च रक्तचाप के इलाज में प्रभावी है। यह दवा नस के माध्यम से दी जाती है और इसका असर बहुत जल्दी शुरू होता है और जल्दी ही खत्म भी हो जाता है। इसे घर पर स्वयं नहीं लगाया जा सकता।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में निम्न रक्तचाप, चक्कर आना, मतली, उल्टी, पसीना आना और इंजेक्शन लगाने की जगह पर दर्द या लालिमा शामिल हैं। गंभीर दुष्प्रभावों में हृदय गति का बहुत धीमा होना, हृदय में रुकावट, सांस लेने में कठिनाई, और हृदय विफलता का बढ़ना शामिल है। यदि आपको सांस लेने में तकलीफ, सीने में दर्द, या बहुत अधिक चक्कर आ रहे हैं, तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसे घर पर स्वयं न लगाएं। यदि आपको अस्थमा, हृदय की समस्या, गुर्दे की बीमारी, या मधुमेह है, तो डॉक्टर को पहले बताएं। इस दवा को देते समय आपकी हृदय गति, रक्तचाप और हृदय की धड़कन की लगातार निगरानी की जाएगी। अपने डॉक्टर को बताएं कि आप कौन-कौन सी अन्य दवाएं ले रहे हैं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर को सूचित करें।
💊 esmocard 100mg injection Uses & Benefits
[{"condition":"Supraventricular tachycardia (SVT)","description":"Used for rapid control of heart rate in patients with SVT, including atrial fibrillation and atrial flutter with rapid ventricular response.","evidence":"Well-established"},{"condition":"Intraoperative and perioperative tachycardia and hypertension","description":"Administered to control heart rate and blood pressure during surgery and in the immediate postoperative period.","evidence":"Well-established"},{"condition":"Acute myocardial ischemia with tachycardia","description":"May be used to reduce heart rate and myocardial oxygen demand in patients with acute coronary syndrome when beta-blockade is appropriate.","evidence":"Moderate"},{"condition":"Thyroid storm","description":"Used as an adjunct to control heart rate in thyrotoxicosis or thyroid storm.","evidence":"Limited"}]
Off-label uses: [{"condition":"Adjunct in electroconvulsive therapy (ECT)","description":"Sometimes used to blunt the hypertensive and tachycardic response during ECT.","evidence":"Limited"},{"condition":"Adjunct in pheochromocytoma management","description":"May be used after alpha-blockade to control tachycardia.","evidence":"Limited"}]
Primary treatment for: Supraventricular tachycardia
Also treats: Atrial fibrillation, Atrial flutter, Intraoperative tachycardia, Perioperative hypertension, Thyroid storm
📋 Drug Information
| Generic Name(s) | Esmolol (100mg) |
| Brand Name | esmocard 100mg injection |
| Manufacturer | Troikaa Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Beta blocker- Cardioselective |
| Route of Administration | Intravenous (IV) injection or infusion |
| Storage | Store at 20°C to 25°C (68°F to 77°F). Do not freeze. Protect from light. Keep in the original container until ready to use. Once diluted, the solution should be used within 24 hours if stored at room temperature or 48 hours if refrigerated. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a cardioselective beta-1 adrenergic receptor blocker. It competitively blocks beta-1 receptors located primarily in the heart, which reduces the effects of catecholamines such as epinephrine and norepinephrine. This leads to a decrease in heart rate, myocardial contractility, and cardiac output, thereby lowering blood pressure and myocardial oxygen demand. At higher doses, it may also block beta-2 receptors in the lungs and blood vessels, but its selectivity for beta-1 receptors is greater than that of non-selective beta-blockers. The rapid onset and short duration of action are due to its rapid hydrolysis by esterases in red blood cells, which allows for quick titration and rapid reversal of effects.
Mechanism Steps
💡 How to Take esmocard 100mg injection
Strength: Injection: 100 mg in 10 mL (10 mg/mL) single-dose vial.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, patient's age, weight, renal function, and clinical response. For supraventricular tachycardia, a typical loading dose is 500 mcg/kg administered over 1 minute, followed by a maintenance infusion of 50 mcg/kg/min for 4 minutes. If the response is inadequate, a second loading dose of 500 mcg/kg may be given over 1 minute, followed by a maintenance infusion of 100 mcg/kg/min for 4 minutes. The infusion may be titrated up to 200 mcg/kg/min as needed. For intraoperative tachycardia and hypertension, a loading dose of 80 mg (approximately 1 mg/kg) may be given over 30 seconds, followed by an infusion of 150 mcg/kg/min, titrated to effect. Continuous monitoring is mandatory. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, particularly bradycardia and hypotension. Dose selection should be cautious, and monitoring should be intensified. No specific dose adjustment is established, but lower doses may be appropriate. |
| Renal Impairment | No dose adjustment is required for esmolol itself in patients with renal impairment. However, the acid metabolite is excreted renally and may accumulate. Monitor for adverse effects and adjust infusion rate as needed. |
| Hepatic Impairment | No dose adjustment is required for hepatic impairment because esmolol is metabolized by red blood cell esterases, not by the liver. |
| Maximum Daily Dose | The maximum recommended maintenance infusion rate is 200 mcg/kg/min. Higher doses have not been studied and may increase the risk of adverse effects. The maximum duration of therapy is typically 24 to 48 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of esmocard 100mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Diltiazem | Major | |
| Digoxin | Major | |
| Clonidine | Major | |
| Other beta-blockers | Major | |
| Insulin | Moderate | |
| NSAIDs | Moderate | |
| Anesthetics | Moderate | |
| Diuretics | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Calcium channel blockers (verapamil, diltiazem)
- Other beta-blockers
- Clonidine
- Digoxin
- Sympathomimetic agents (e.g., epinephrine, norepinephrine)
⚡ Moderate Interactions
- Insulin and oral hypoglycemic agents
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Anesthetic agents
🍷 Alcohol Interaction
Alcohol may enhance the hypotensive and sedative effects of this medicine. Patients should avoid alcohol during treatment and for at least 24 hours after discontinuation, as it can increase the risk of dizziness, fainting, and falls.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Second- or third-degree heart block without a functioning pacemaker","Cardiogenic shock","Decompensated heart failure","Severe bronchospasm or asthma","Known hypersensitivity to esmolol or any component of the formulation","Pulmonary hypertension"]
⚠️ Warnings & Precautions
["Administer only in a monitored setting with continuous cardiac monitoring.","Use with caution in patients with asthma or COPD; may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients.","May mask symptoms of hyperthyroidism.","Use with caution in patients with renal impairment; metabolite may accumulate.","Avoid abrupt discontinuation of other beta-blockers when starting this medicine.","May cause hypotension; monitor blood pressure closely.","Not for home use; must be administered by healthcare professionals."]
🤱 Lactation Safety
It is not known whether esmolol is excreted in human breast milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose of this medicine can cause severe bradycardia, hypotension, heart block, and heart failure. Treatment is supportive and symptomatic. Discontinue the infusion immediately. For severe bradycardia, administer atropine or isoproterenol. For hypotension, use intravenous fluids and vasopressors. For bronchospasm, use beta-2 agonists. Glucagon may be considered for refractory bradycardia or hypotension. Hemodialysis is not effective in removing esmolol due to its rapid metabolism.
⏰ Missed Dose
This medicine is administered by healthcare professionals in a controlled setting. Missed doses are not applicable for patients. If a scheduled dose is missed in a hospital setting, the medical team will determine the appropriate action based on the clinical situation.
Additional Safety Advice
This medicine must only be administered by a qualified healthcare professional in a hospital or monitored setting. Do not attempt to use this medicine at home. Inform your doctor if you have asthma, chronic obstructive pulmonary disease, heart failure, kidney problems, or diabetes, as this medicine may not be suitable for you. Your heart rate, blood pressure, and heart rhythm will be closely monitored during and after administration. Tell your doctor about all other medicines you are taking, especially calcium channel blockers, digoxin, clonidine, and other beta-blockers, as interactions can occur. Do not stop or change any other heart medicines without your doctor's advice. If you experience severe dizziness, difficulty breathing, or chest pain during or after the injection, inform the medical staff immediately. Pregnant or breastfeeding women should inform their doctor before receiving this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially bradycardia and hypotension. Close monitoring of heart rate and blood pressure is essential. Dose selection should be cautious, and lower doses may be appropriate. Renal function should be assessed as the metabolite may accumulate.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before receiving this medicine. It is not known whether this medicine affects fertility. Use during pregnancy only if clearly needed. Effective contraception is recommended during treatment if you are of childbearing potential.
🏥 Post-Surgery Considerations
After surgery, this medicine may be continued if needed to control heart rate and blood pressure. Your doctor will monitor your vital signs and transition you to oral medication when appropriate. Follow your surgeon's instructions for postoperative care, including activity restrictions and wound care.
🦷 Dental Procedures
Inform your dentist if you have received this medicine recently. It may interact with local anesthetics containing epinephrine, potentially causing hypertension or bradycardia. Your dentist may need to adjust the anesthetic used. Generally, routine dental procedures can be performed after your condition is stable.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
After receiving this medicine, you may feel dizzy or lightheaded. Avoid strenuous exercise or heavy lifting until your doctor says it is safe. Start with light activities and gradually increase as tolerated. If you experience chest pain, shortness of breath, or severe dizziness during exercise, stop immediately and seek medical attention.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital setting, so it does not directly impact your daily work routine. However, after receiving it, you may feel dizzy or tired for a few hours. Avoid driving or operating heavy machinery until you feel fully alert. Your doctor will advise when you can resume normal activities.
🛑 When to Stop This Medicine
This medicine is stopped by your healthcare provider based on your clinical response. Do not attempt to stop or adjust the infusion yourself. If you are transitioning to oral medication, your doctor will guide you. If you experience severe side effects, the medical team will discontinue the infusion immediately.
📅 Long-Term Use Effects
This medicine is intended for short-term use, typically not exceeding 24 to 48 hours. Long-term effects are not well studied because it is not used chronically. Prolonged infusion may lead to accumulation of the acid metabolite, especially in renal impairment, and may increase the risk of adverse effects. Monitoring of heart rate, blood pressure, and renal function is recommended during prolonged use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For long-term heart rate control after acute management.
Evidence: Well-establishedAlternative for rate control in patients who cannot take beta-blockers.
Evidence: Well-establishedUsed for acute termination of supraventricular tachycardia.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor that you received this medicine. In general, vaccinations can be given as per schedule unless contraindicated for other reasons.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in direct sunlight
✅ DO
Use diluted solution within 24 hours at room temperature
❌ DON'T
Do not use if solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is administered in a hospital setting and is not for self-administration during travel. If you are traveling after receiving this medicine, carry a copy of your prescription and medical records. Inform your doctor before travel, especially if you are transitioning to oral medication. Store the injection in its original packaging, protected from light and extreme temperatures. Do not freeze. If you need to carry it, use a cooler bag and ensure it remains at room temperature (20-25°C). Check customs regulations for carrying prescription medicines across borders.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1 to 2 minutes after intravenous administration.
A: The effects last for about 10 to 20 minutes after the infusion is stopped.
A: No, this medicine must be given by a healthcare professional in a hospital or monitored setting.
A: It should be used during pregnancy only if clearly needed. Consult your doctor.
A: Common side effects include low blood pressure, dizziness, nausea, and injection site pain.
🤔 Common Patient Concerns
🔄 Substitutes for esmocard 100mg injection
View AllAlternative brands with exact same active ingredient:
-
miniblock 100mg injectionUSV Ltd ₹45.00 80.2% CHEAPER
-
cardesmo 100mg injectionSG Pharma ₹180.00 21% CHEAPER
-
esocard 100mg injectionSamarth Life Sciences Pvt Ltd ₹276.90 21.5% COSTLIER
-
neotach 100mg injectionNeon Laboratories Ltd ₹276.90 21.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Esmolol can be taken at home for palpitations.
Fact: Esmolol is an intravenous medicine that must be given in a hospital or monitored setting. It is not for home use. - Myth: Esmolol is a long-acting beta-blocker.
Fact: Esmolol is ultra-short-acting, with effects lasting only 10-20 minutes after stopping the infusion. - Myth: Esmolol is safe for everyone with high blood pressure.
Fact: Esmolol is contraindicated in certain conditions like severe bradycardia, heart block, and decompensated heart failure.
🔄 Alternative Options
Generic Alternatives
- Esmolol hydrochloride injection
Brand Alternatives
- Esocard 100mg injection
- Brevibloc