duvent-pd syrup - Theophylline (50mg/5ml) + Ambroxol (15mg/5ml) medicine

Duvent-PD Syrup: Complete Medicine Guide

No reviews yet
🏭 Hygeia Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for combination.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe palpitations or irregular heartbeat
  • Seizures or convulsions
  • Difficulty breathing or worsening asthma
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Blood in vomit or black stools
  • Severe abdominal pain

If experiencing severe symptoms, call emergency services immediately.

What is duvent-pd syrup used for?

This medicine is a combination of theophylline and ambroxol used to treat bronchospasm and thick mucus in asthma, COPD, and bronchitis. It relaxes airways and thins mucus, making breathing easier.

  • Generic Name: Theophylline + Ambroxol
  • Manufacturer: Hygeia Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 duvent-pd syrup के बारे में (Hindi Summary)

उपयोग: यह दवा थियोफिलिन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग अस्थमा, सीओपीडी और ब्रोंकाइटिस में श्वसन मार्ग की रुकावट और बलगम को कम करने के लिए किया जाता है। यह वायुमार्ग को फैलाकर सांस लेना आसान बनाती है और गाढ़े बलगम को पतला करके बाहर निकालने में मदद करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, सिरदर्द, बेचैनी और दिल की धड़कन बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन, दौरे और गंभीर एलर्जी प्रतिक्रियाएं हो सकती हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक बढ़ाने से पहले डॉक्टर से सलाह लें। शराब और कैफीन युक्त पदार्थों से बचें। यदि आपको हृदय, यकृत, गुर्दे या दौरे की समस्या है तो डॉक्टर को बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 duvent-pd syrup Uses & Benefits

[{"condition":"Bronchial asthma","description":"Helps relieve bronchospasm and loosen mucus to improve breathing.","evidence":"Established for theophylline; ambroxol used as adjunct."},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Used to reduce airway obstruction and facilitate mucus clearance.","evidence":"Established for theophylline; ambroxol used as adjunct."},{"condition":"Bronchitis","description":"Provides symptomatic relief from cough and chest congestion.","evidence":"Limited for combination; individual components used."}]

Off-label uses: []

Primary treatment for: Bronchial asthma

Also treats: COPD, Bronchitis

📋 Drug Information

Generic Name(s)Theophylline + Ambroxol
Brand NameAmbrolite ST 100 mg/30 mg/2 mg Tablet
ManufacturerHygeia Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassBronchodilator (Xanthine) + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid caffeine and alcohol while taking this medicine.
3
Do not exceed the prescribed dose; theophylline has a narrow therapeutic window.
4
Inform your doctor if you have heart, liver, kidney, or seizure disorders.
5
Report any palpitations, restlessness, or nausea to your doctor.
6
Keep regular follow-up appointments for monitoring.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Wheezing
This medicine is commonly prescribed for this.
Likely Use
Chest congestion with thick mucus
This medicine helps thin and clear mucus.
Likely Use
Dry cough
This medicine is not for dry cough.
Not Primary
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTheophylline is well absorbed from the gastrointestinal tract. Ambroxol is rapidly absorbed after oral administration. Food may affect the rate but not the extent of absorption.
DistributionTheophylline distributes widely into body tissues and fluids, including the central nervous system. Ambroxol distributes into lung tissue and bronchial secretions.
Protein BindingTheophylline is approximately 40% bound to plasma proteins. Ambroxol is approximately 90% bound to plasma proteins.
MetabolismTheophylline is metabolized in the liver by cytochrome P450 enzymes (CYP1A2, CYP2E1, CYP3A4). Ambroxol is metabolized in the liver by glucuronidation and some oxidation.
Half-LifeTheophylline half-life varies (3-12 hours in adults). Ambroxol half-life is approximately 7-12 hours.
ExcretionTheophylline and its metabolites are excreted primarily in urine. Ambroxol and its metabolites are excreted mainly in urine.
BioavailabilityTheophylline oral bioavailability is approximately 96%. Ambroxol oral bioavailability is about 70-80%.
Onset of ActionBronchodilation occurs within 30 minutes to 2 hours after oral theophylline. Ambroxol's mucolytic effect may take several hours to days.
Peak Plasma TimeTheophylline peak plasma levels occur 1-2 hours after oral administration (immediate release). Ambroxol peak levels occur within 1-3 hours.
Duration of ActionTheophylline bronchodilation lasts 6-12 hours. Ambroxol's effect lasts several hours.

How It Works

Theophylline inhibits phosphodiesterase enzymes, increasing cyclic AMP levels, which leads to relaxation of bronchial smooth muscle. It also blocks adenosine receptors, contributing to bronchodilation and mild anti-inflammatory effects. Ambroxol increases serous bronchial secretion, reduces mucus viscosity, and stimulates surfactant production, enhancing mucociliary clearance.

Mechanism Steps

1
Phosphodiesterase inhibition: Theophylline inhibits phosphodiesterase, increasing cyclic AMP in bronchial smooth muscle cells, causing relaxation.
2
Adenosine receptor blockade: Theophylline blocks adenosine receptors, preventing adenosine-induced bronchoconstriction.
3
Mucolytic action of ambroxol: Ambroxol breaks down acidic mucopolysaccharides in mucus, reducing its viscosity and making it easier to cough out.
4
Surfactant stimulation: Ambroxol stimulates surfactant production in type II pneumocytes, improving airway lubrication and clearance.

💡 How to Take duvent-pd syrup

Strength: Each 5 ml contains Theophylline 50 mg and Ambroxol 15 mg.

1Shake the bottle well before use.
2Measure the dose using the provided measuring cup or spoon.
3Take the medicine with or after food to reduce stomach upset.
4Swallow the syrup directly; do not mix with other liquids unless advised.
5Follow the prescribed schedule consistently.

Dosage Information

Adult DosageThe usual adult dose is 5-10 ml (1-2 teaspoons) three to four times daily, or as directed by a physician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced clearance. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be needed in renal impairment. Consult a doctor.
Hepatic ImpairmentDose adjustment may be needed in hepatic impairment. Consult a doctor.
Maximum Daily DoseThe maximum daily dose should not exceed 40 ml (8 teaspoons) in adults, or as prescribed. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine-containing foods and drinks
Limit
May increase restlessness and heart rate.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of duvent-pd syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persistent, consult doctor.
Vomiting (Common (5-10%))
Stay hydrated. Consult doctor if severe.
Headache (Common (5-10%))
Rest and hydrate. Consult if severe.
Restlessness (Common (5-10%))
Avoid caffeine. Consult if bothersome.
Increased heart rate (Common (5-10%))
Monitor. Consult if persistent or symptomatic.

🚨 Serious Side Effects

Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if palpitations, dizziness, or fainting occur.
Seizures (Rare (<0.1%))
Seek emergency care immediately.
Severe allergic reactions (Rare (<0.1%))
Seek emergency care if rash, swelling, or difficulty breathing occurs.
Peptic ulcer exacerbation (Rare (<0.1%))
Consult doctor if severe stomach pain or black stools occur.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bleeding or bruising to doctor.
Severe skin reactions (e.g., Stevens-Johnson syndrome)
Seek immediate medical attention if rash with blisters or peeling skin occurs.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Erythromycin Major
Propranolol Major
Phenytoin Moderate
Rifampicin Moderate
Cimetidine Moderate
Caffeine Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Ciprofloxacin
  • Erythromycin
  • Propranolol

⚡ Moderate Interactions

  • Phenytoin
  • Rifampicin
  • Cimetidine

🍷 Alcohol Interaction

Alcohol may increase the risk of gastrointestinal side effects and may affect theophylline metabolism. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to theophylline or ambroxol","Active peptic ulcer","Severe cardiac arrhythmias","Uncontrolled seizure disorders","Children under 2 years (unless prescribed)"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease, hypertension, or seizure disorders.","Avoid in patients with active peptic ulcer.","May impair ability to drive or operate machinery.","Do not exceed prescribed dose.","Monitor theophylline levels to avoid toxicity."]

🤱 Lactation Safety

Theophylline and ambroxol may pass into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, restlessness, palpitations, seizures, and cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed. Do not increase the dose without consulting your doctor. Avoid alcohol and caffeine-containing products as they may worsen side effects. Inform your doctor if you have heart, liver, kidney, or seizure disorders. Do not use this medicine for sudden severe breathing attacks without medical advice. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects and may require lower doses. Monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. Use only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Stay well hydrated to help thin mucus.
😴
Use a humidifier to keep airways moist.
💧
Practice breathing exercises as advised.
🧘
Get adequate rest and avoid triggers.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience palpitations or dizziness. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit caffeine and alcohol.
Stay hydrated.
Avoid heavy, fatty meals if they worsen symptoms.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or restlessness. Avoid driving or operating machinery until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Stopping suddenly may worsen your condition.

📅 Long-Term Use Effects

Long-term use requires monitoring of theophylline levels, heart rate, and liver function. Toxicity may occur if levels become too high. Regular follow-up is essential.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and ease breathing.

Evidence: Supportive
Chest physiotherapy

Assists in clearing mucus from airways.

Evidence: Supportive

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Consult your doctor about appropriate vaccinations (e.g., influenza, pneumococcal) as they can prevent respiratory infections.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with chronic bronchitis
He was prescribed this medicine for persistent cough with thick mucus. After taking it regularly with food, he noticed significant relief in chest congestion and easier breathing within a week. He was advised to avoid caffeine and to report any palpitations.
💡 Lesson: Consistent use with food and avoiding caffeine improves tolerability and effectiveness.
👤 A 50-year-old woman with COPD
She started this medicine as part of her COPD management. She experienced mild nausea initially, which subsided after taking it with meals. Her breathing improved, and she was able to perform daily activities with less breathlessness.
💡 Lesson: Taking the medicine with food helps minimize gastrointestinal side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Bronchodilation may start within 30 minutes to 2 hours, but full effects on mucus may take a few days.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you take, as interactions can occur.

Q: Is it safe during pregnancy?

A: Consult your doctor; use only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for duvent-pd syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any cough.
    Fact: It is specifically for bronchospasm and thick mucus; not for dry cough or common cold.
  • Myth: It is safe to double the dose if you miss one.
    Fact: Doubling the dose can cause serious side effects. Follow missed dose instructions.

🔄 Alternative Options

Generic Alternatives

  • Theophylline + Ambroxol syrup (generic)

Brand Alternatives

  • Duvent-PD

📊 Comparison with Similar Medicines

[{"medicine":"Theophylline + Ambroxol","composition":"Theophylline 50mg/5ml + Ambroxol 15mg/5ml","uses":"Bronchospasm with thick mucus","notes":"Combination product"},{"medicine":"Salbutamol + Ambroxol","composition":"Salbutamol 2mg/5ml + Ambroxol 15mg/5ml","uses":"Bronchospasm with thick mucus","notes":"Alternative bronchodilator"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory