duraject 30mg tablet - Dapoxetine (30mg) medicine

Duralast 30 Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Akumentis Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for premature ejaculation
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Agitation, hallucinations, fast heartbeat, fever, or muscle twitching
  • Fainting or loss of consciousness
  • Severe dizziness or lightheadedness upon standing
  • Signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing
  • Changes in mood or behaviour, especially thoughts of self-harm
  • Chest pain or irregular heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is duraject 30mg tablet used for?

This medicine is a prescription oral tablet containing dapoxetine 30 mg, used to treat premature ejaculation in adult men. It works by increasing serotonin levels in the brain to delay ejaculation.

  • Generic Name: Dapoxetine
  • Manufacturer: Akumentis Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 duraject 30mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा दपोक्सेटीन 30 मिलीग्राम युक्त एक प्रिस्क्रिप्शन टैबलेट है, जिसका उपयोग वयस्क पुरुषों में शीघ्रपतन के इलाज के लिए किया जाता है। यह मस्तिष्क में सेरोटोनिन के स्तर को बढ़ाकर स्खलन में देरी करने और नियंत्रण में सुधार करने में मदद करती है। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, सिरदर्द, चक्कर आना, मुँह सूखना और अनिद्रा शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें बेहोशी, मनोदशा में बदलाव और सेरोटोनिन सिंड्रोम शामिल हो सकते हैं। यदि आपको घबराहट, मतिभ्रम, तेज़ धड़कन, बुखार या मांसपेशियों में ऐंठन का अनुभव हो तो तुरंत चिकित्सा सहायता लें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। 24 घंटे में एक से अधिक खुराक न लें। टैबलेट को पानी के साथ पूरा निगलें, चबाएं नहीं। इस दवा के साथ शराब का सेवन न करें। यदि आपको दौरे, ग्लूकोमा या रक्तस्राव विकार का इतिहास है तो अपने डॉक्टर को बताएं। इस दवा को अचानक बंद न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 duraject 30mg tablet Uses & Benefits

[{"condition":"Premature ejaculation","description":"This medicine is used to treat premature ejaculation in adult men by delaying ejaculation and improving control.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Not established from the available information.","description":"Not established from the available information.","evidence":"Not established from the available information."}]

Primary treatment for: Premature ejaculation

📋 Drug Information

Generic Name(s)Dapoxetine
Brand NameAppynite
ManufacturerAkumentis Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassSelective Seretonin Reuptake inhibitors (SSRIs)
Route of AdministrationOral
StorageStore at room temperature (15-30°C), away from moisture and direct sunlight.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine approximately 1 to 3 hours before anticipated sexual activity.
2
Do not take more than one dose in 24 hours.
3
Avoid alcohol while taking this medicine to reduce the risk of dizziness.
4
Inform your doctor about all other medicines you are taking, especially MAO inhibitors and thioridazine.
5
Do not drive or operate heavy machinery until you know how this medicine affects you.
6
Report any mood changes or unusual thoughts to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Premature ejaculation
This medicine is commonly prescribed for this condition.
Likely Use
❌
Erectile dysfunction
This medicine is not a primary treatment for erectile dysfunction.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 1 to 2 hours.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 enzymes CYP2D6, CYP3A4, and CYP2B6.
Half-LifeThe initial half-life is approximately 1.5 hours, and the terminal half-life is about 19 hours.
ExcretionThis medicine is excreted mainly in the urine as metabolites.
BioavailabilityThe absolute bioavailability of this medicine is approximately 42%.
Onset of ActionThe onset of action is typically within 1 to 2 hours after taking the tablet.
Peak Plasma TimePeak plasma concentration is reached in about 1 to 2 hours.
Duration of ActionThe effect of this medicine lasts for approximately 24 hours.

How It Works

This medicine works by selectively inhibiting the reuptake of serotonin in the brain. Serotonin is a neurotransmitter that plays a key role in mood and sexual function. By blocking its reuptake, this medicine increases serotonin levels in the synaptic cleft, which helps to delay ejaculation and improve control over ejaculation.

Mechanism Steps

1
Inhibition of serotonin reuptake: This medicine binds to the serotonin transporter and blocks the reuptake of serotonin into presynaptic neurons.
2
Increased serotonin levels: As a result, serotonin accumulates in the synaptic cleft, enhancing serotonergic neurotransmission.
3
Delayed ejaculation: The increased serotonin activity in the brain helps to delay ejaculation and improve control.

💡 How to Take duraject 30mg tablet

Strength: 30 mg immediate-release tablet

1Take this medicine orally with a glass of water.
2Take it approximately 1 to 3 hours before anticipated sexual activity.
3Do not take more than one dose in 24 hours.
4Swallow the tablet whole; do not crush or chew it.
5Take it with or without food, but taking it with food may reduce nausea.

Dosage Information

Adult DosageThe recommended dose of this medicine is 30 mg taken orally once daily, approximately 1 to 3 hours before anticipated sexual activity. The dose may be increased to 60 mg if needed, but the maximum recommended dose is 60 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageThis medicine is not recommended for use in elderly patients due to limited data and increased risk of side effects.
Renal ImpairmentThis medicine is not recommended for use in patients with moderate to severe renal impairment.
Hepatic ImpairmentThis medicine is not recommended for use in patients with severe hepatic impairment.
Maximum Daily Dose60 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Grapefruit
Avoid
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of duraject 30mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Dry mouth (Common (5-10%))
Drink plenty of water and chew sugar-free gum.
Insomnia (Common (5-10%))
Practice good sleep hygiene. Consult doctor if it persists.

🚨 Serious Side Effects

Serotonin syndrome (Rare (<0.1%))
Seek immediate medical attention if you experience agitation, hallucinations, fast heartbeat, fever, or muscle twitching.
Syncope (fainting) (Rare (<0.1%))
Sit or lie down immediately and seek medical help if you faint.
Orthostatic hypotension (Uncommon (0.1-1%))
Stand up slowly. Consult doctor if you feel dizzy or lightheaded.

⚠️ Rare Side Effects

Mood changes
Consult doctor if you notice changes in mood or behaviour.
Allergic reactions
Seek immediate medical help if you experience rash, itching, swelling, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Thioridazine Major
Other SSRIs Major
CYP2D6 inhibitors Moderate
CYP3A4 inhibitors Moderate
NSAIDs Minor

🚨 Major Interactions

  • MAO inhibitors
  • Thioridazine
  • Other SSRIs

⚡ Moderate Interactions

  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine, as it can increase the risk of dizziness, drowsiness, and other side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to dapoxetine","History of mania or bipolar disorder","Severe hepatic impairment","Moderate to severe renal impairment","Concomitant use with MAO inhibitors","Concomitant use with thioridazine","History of syncope","History of seizures"]

⚠️ Warnings & Precautions

["Do not use in women or children.","Avoid alcohol while taking this medicine.","Use with caution in patients with a history of bleeding disorders.","Use with caution in patients with glaucoma.","Do not drive or operate machinery until you know how this medicine affects you.","Do not stop taking this medicine suddenly without consulting your doctor."]

🤱 Lactation Safety

Not established from the available information. This medicine is not intended for use in women.

💊 Overdose Management

Seek immediate medical attention in case of overdose. Symptoms may include nausea, vomiting, dizziness, and serotonin syndrome. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than one dose in 24 hours. Swallow the tablet whole with a glass of water; do not crush or chew it. Avoid drinking alcohol while taking this medicine, as it can increase the risk of dizziness and other side effects. Inform your doctor if you have a history of seizures, glaucoma, or bleeding disorders. Do not stop taking this medicine suddenly without consulting your doctor, as this can cause withdrawal symptoms. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

This medicine is not recommended for use in elderly patients due to limited data and increased risk of side effects.

🤰 Pregnancy Planning (TTC)

This medicine is not intended for use in women. If you are planning pregnancy, consult your doctor.

🏥 Post-Surgery Considerations

Consult your doctor before resuming this medicine after surgery, especially if you have been advised to avoid certain medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the risk of sexual dysfunction.
🥗
Regular exercise can improve overall sexual health.
😴
Practice stress-reduction techniques like meditation or yoga.
💧
Get adequate sleep to support overall well-being.
🧘
Communicate openly with your partner about your condition.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience dizziness or lightheadedness while taking this medicine. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also affect your ability to concentrate.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or if your condition does not improve, your doctor may adjust or stop the treatment.

📅 Long-Term Use Effects

Long-term use of this medicine should be under the supervision of a doctor. Regular monitoring for mood changes, blood pressure, and signs of serotonin syndrome is recommended. Do not stop the medicine abruptly without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Behavioural therapy

Techniques such as the squeeze technique and start-stop method can help manage premature ejaculation.

Evidence: Well-established
Couples counselling

Can help address relationship issues and improve communication.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, consult your doctor about dosing adjustments. Check local customs regulations regarding prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with premature ejaculation
He was prescribed this medicine by his doctor. He took it 2 hours before sexual activity and noticed a significant improvement in control and satisfaction. He experienced mild nausea initially, which subsided after taking it with food.
💡 Lesson: Taking this medicine with food can reduce nausea and improve tolerability.
👤 A 42-year-old man with a history of dizziness
He started this medicine but experienced dizziness and lightheadedness. He consulted his doctor, who advised him to stand up slowly and avoid driving. His symptoms improved after a few days.
💡 Lesson: Report any dizziness to your doctor; dose adjustment or precautions may be needed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts working within 1 to 2 hours after taking the tablet.

Q: Can I take this medicine every day?

A: This medicine is usually taken as needed, 1 to 3 hours before sexual activity, and not more than once daily. Consult your doctor for personalized advice.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for duraject 30mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a treatment for erectile dysfunction.
    Fact: This medicine is specifically for premature ejaculation and does not treat erectile dysfunction.
  • Myth: This medicine can be taken daily like a vitamin.
    Fact: This medicine should only be taken as needed, 1 to 3 hours before sexual activity, and not more than once daily.

🔄 Alternative Options

Generic Alternatives

  • Dapoxetine 30 mg tablet

Brand Alternatives

  • Duralast 30 tablet

📊 Comparison with Similar Medicines

[{"medicine":"Dapoxetine 30 mg","strength":"30 mg","dosage_form":"Tablet","route":"Oral","release_type":"Immediate release"},{"medicine":"Dapoxetine 60 mg","strength":"60 mg","dosage_form":"Tablet","route":"Oral","release_type":"Immediate release"}]

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