Biokez-AD Shampoo: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, or difficulty breathing.
- Severe skin reaction: blistering, peeling, or widespread rash.
- Signs of infection: increased redness, swelling, pus, or pain.
- No improvement after 4 weeks of regular use.
- Hair loss that is sudden or severe.
- Severe burning or irritation that persists.
If experiencing severe symptoms, call emergency services immediately.
What is dufklin lotion used for?
This medicine is a medicated shampoo containing cetrimide and ketoconazole. It is used to treat dandruff, seborrheic dermatitis, and scalp fungal infections. It works by killing fungi and reducing bacteria on the scalp. Apply to wet hair, lather, leave for 3-5 minutes, and rinse. Use twice weekly initially, then once weekly.
- Generic Name: Cetrimide (0.5% w/v) + Ketoconazole (2% w/v)
- Manufacturer: Blaze Remedies
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dufklin lotion के बारे में (Hindi Summary)
उपयोग: यह दवा एक मेडिकेटेड शैम्पू है जिसमें सेट्रीमाइड और कीटोकोनाज़ोल होते हैं। यह डैंड्रफ, सेबोरहाइक डर्मेटाइटिस और स्कैल्प फंगल इन्फेक्शन के इलाज के लिए उपयोग किया जाता है। यह खुजली, पपड़ी और जलन को कम करने में मदद करता है। इसे गीले बालों और स्कैल्प पर लगाएं, झाग बनाएं, 3-5 मिनट छोड़ें और धो लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में स्कैल्प में हल्की जलन, सूखापन, खुजली या जलन शामिल हैं। कभी-कभी बालों की बनावट बदल सकती है। दुर्लभ मामलों में एलर्जी प्रतिक्रिया हो सकती है। यदि गंभीर या लगातार दुष्प्रभाव हों तो डॉक्टर से सलाह लें।
सुरक्षा सलाह: केवल बाहरी उपयोग के लिए। आंखों, नाक, मुंह और अन्य श्लेष्म झिल्ली के संपर्क से बचें। 12 वर्ष से कम उम्र के बच्चों में बिना डॉक्टर की सलाह के उपयोग न करें। यदि आपको किसी भी घटक से एलर्जी है तो उपयोग न करें। टूटी या संक्रमित त्वचा पर न लगाएं। यदि स्थिति बिगड़ती है या 4 सप्ताह में सुधार नहीं होता है, तो डॉक्टर से सलाह लें।
💊 dufklin lotion Uses & Benefits
[{"condition":"Dandruff","description":"Reduces flaking and itching of the scalp caused by Malassezia yeast.","evidence":"Well-established"},{"condition":"Seborrheic dermatitis","description":"Helps control scaling, redness, and itching on the scalp and other oily areas.","evidence":"Well-established"},{"condition":"Tinea versicolor","description":"May be used to treat this fungal skin infection when it affects the scalp or adjacent areas.","evidence":"Moderate"},{"condition":"Scalp psoriasis","description":"May help reduce scaling and itching, though it is not a primary treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Fungal infections of the skin (other than scalp)","description":"Sometimes used off-label for body fungal infections due to ketoconazole content.","evidence":"Limited"}]
Primary treatment for: Dandruff and seborrheic dermatitis
Also treats: Tinea versicolor, Scalp psoriasis
📋 Drug Information
| Generic Name(s) | Cetrimide (0.5% w/v) + Ketoconazole (2% w/v) |
| Brand Name | dufklin lotion |
| Manufacturer | Blaze Remedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Keep away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ketoconazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This leads to increased permeability and leakage of cellular contents, ultimately causing fungal cell death. Cetrimide is a quaternary ammonium compound that acts as a surfactant and antiseptic. It disrupts bacterial cell membranes and helps remove debris and oil from the scalp, enhancing the antifungal effect.
Mechanism Steps
💡 How to Take dufklin lotion
Strength: Shampoo containing Cetrimide 0.5% w/v and Ketoconazole 2% w/v.
Dosage Information
| Adult Dosage | Wet hair and scalp thoroughly. Apply a sufficient amount to cover the scalp and hair, lather, and leave on for 3-5 minutes. Rinse thoroughly with water. Use twice weekly for 2-4 weeks, then once weekly or as directed by a doctor. Dose must be individualized by a qualified clinician based on indication, age, and response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients. Use as directed by a doctor. |
| Renal Impairment | No dose adjustment is required for renal impairment when used topically. |
| Hepatic Impairment | No dose adjustment is required for hepatic impairment when used topically. |
| Maximum Daily Dose | Not applicable for topical use. Use as directed by a doctor. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dufklin lotion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cetrimide, ketoconazole, or any component of the formulation.","Not for use in children under 12 years without medical advice.","Do not use on broken or inflamed skin."]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes and mucous membranes.","If accidental contact with eyes occurs, rinse thoroughly with water.","Do not use for vaginal infections.","If condition worsens or persists after 4 weeks, consult a doctor.","Keep out of reach of children.","Pregnant or breastfeeding women should consult a doctor before use."]
🤱 Lactation Safety
It is not known whether ketoconazole or cetrimide pass into breast milk after topical application. Consult a doctor before use. Avoid applying to the breast area to prevent infant exposure.
💊 Overdose Management
Overdose is unlikely due to topical application. If swallowed, seek medical attention immediately. Symptoms of ingestion may include nausea, vomiting, and abdominal pain. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use on children under 12 years without medical advice. Do not use if you are allergic to cetrimide, ketoconazole, or any other ingredients. Do not apply to broken or infected skin. If your condition worsens or does not improve after 4 weeks, consult a doctor. Keep out of reach of children. Do not use for vaginal infections. Avoid using other topical products on the same area unless advised. Pregnant or breastfeeding women should consult a doctor before use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
No specific dose adjustment is required for elderly patients. Use as directed by a doctor. Monitor for any signs of skin irritation.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. Topical absorption is minimal, but safety is not fully established.
🏥 Post-Surgery Considerations
No specific precautions after surgery. Avoid applying to surgical wounds or broken skin.
🦷 Dental Procedures
No specific considerations for dental procedures. This medicine is for scalp use only.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise precautions are needed while using this medicine. However, avoid swimming immediately after application to prevent washing it off.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine has no impact on your ability to drive or operate machinery. It is applied topically and does not cause drowsiness.
🛑 When to Stop This Medicine
Stop using this medicine and consult a doctor if your condition worsens, if you experience severe side effects, or if there is no improvement after 4 weeks of regular use. Do not stop without consulting your doctor if you are using it for a chronic condition.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when used as directed. However, prolonged use may lead to scalp dryness or irritation. If you need to use it continuously for more than 4 weeks, consult a doctor. Regular monitoring for any signs of irritation or allergic reaction is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another medicated shampoo for dandruff and seborrheic dermatitis.
Evidence: Well-establishedOver-the-counter shampoo for mild dandruff.
Evidence: Well-establishedUsed for scalp psoriasis and seborrheic dermatitis.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interaction with vaccines. You can receive vaccines while using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. No time zone adjustments are needed for topical use. Declare it at customs if required. Keep it in your carry-on luggage if traveling by air.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice improvement in symptoms within 1-2 weeks of regular use. Full benefit may take up to 4 weeks.
A: This product is formulated for the scalp. Using it on the face may cause irritation. Consult a doctor for facial seborrheic dermatitis.
A: It is not recommended for children under 12 years without medical advice. Consult a pediatrician.
A: Consult your doctor before use. Topical absorption is minimal, but safety is not fully established.
A: Apply as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for dufklin lotion
View AllAlternative brands with exact same active ingredient:
-
biokez-ad shampooEright Healthcare ₹173.40 13.3% CHEAPER
-
ketodac plus shampooIkon Remedies Pvt Ltd ₹210.94 5.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This shampoo can cure dandruff permanently.
Fact: It controls symptoms but does not cure the underlying condition. Regular maintenance may be needed. - Myth: More frequent use gives faster results.
Fact: Using more often than directed may irritate the scalp. Follow the recommended schedule. - Myth: It can be used on the face for acne.
Fact: This product is formulated for the scalp. Using it on the face may cause irritation.
🔄 Alternative Options
Generic Alternatives
- Cetrimide + Ketoconazole shampoo (generic)