dsorolen lotion - Uses, Price, Side Effects & Substitutes
What is dsorolen lotion used for?
Amosan 25mg Tablet (Trioxasalen) is used to treat DERMA. It contains Trioxasalen (0.2% w/v), which Intercalates into DNA and upon UVA exposure forms cross-links, inhibiting DNA sy. Always consult your doctor before use. Take as prescribed.
- Generic Name: Trioxasalen
- Manufacturer: DWD Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ dsorolen lotion Uses & Benefits
Psoriasis, vitiligo, mycosis fungoides, and other photosensitive dermatoses.
Off-label uses: Eczema, alopecia areata, lichen planus.
๐ Drug Information
| Generic Name(s) | Trioxasalen |
| Brand Name | Amosan 25mg Tablet |
| Manufacturer | DWD Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Psoralen & derivatives |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Intercalates into DNA and upon UVA exposure forms cross-links, inhibiting DNA synthesis and cell proliferation.
Mechanism Steps
๐ก How to Take dsorolen lotion
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dsorolen lotion
โ Common Side Effects
- Nausea
- Dizziness
- Headache
- Pruritus
- Erythema
๐จ Serious Side Effects
- Severe phototoxicity
- Skin cancer
- Cataracts
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Allergic reactions
- Peripheral neuropathy
- Pulmonary fibrosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Photosensitizing agents | Major | Enhanced photosensitivity |
| Corticosteroids | Major | Increased risk of skin atrophy |
| Antihistamines | Moderate | Possible additive sedation |
| Sulfonamides | Moderate | Increased photosensitivity |
| Tetracyclines | Moderate | Increased photosensitivity |
| Alcohol | Minor | Increased photosensitivity |
| Caffeine | Minor | Possible increased CNS stimulation |
๐จ Major Interactions
- Anticoagulants
- Photosensitizing agents
- Corticosteroids
โก Moderate Interactions
- Antihistamines
- Sulfonamides
- Tetracyclines
โน๏ธ Minor Interactions
- Alcohol
- Caffeine
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase absorption.
๐ท Alcohol Interaction
May increase photosensitivity and risk of adverse effects.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to trioxasalen; porphyria; melanoma; severe hepatic or renal impairment; pregnancy.
๐ Monitoring Parameters
Liver function tests, renal function, skin examination for phototoxicity, eye examination.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Induce emesis or gastric lavage; symptomatic and supportive care; avoid UVA exposure.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for dsorolen lotion
View AllAlternative brands with exact same active ingredient (Trioxasalen (0.2% w/v)):
-
neosoralen lotionMac Laboratories Ltd โน50.86 43.5% CHEAPER
-
troid lotionResilient Cosmecueticals Pvt Ltd โน52.78 41.4% CHEAPER
-
q on lotionTetramed Biotek Pvt Ltd โน74.25 17.5% CHEAPER
-
trikare 0.2% lotionDermakare Pharmaceuticals Pvt Ltd โน84.38 6.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.