clenorush oral gel - Clotrimazole (NA) + Choline Salicylate (NA) medicine

clenorush oral gel

4.6 (15 reviews)
๐Ÿญ DWD Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is clenorush oral gel used for?

Clenorush Oral Gel (Clotrimazole + Choline Salicylate) is used to treat ANTI INFECTIVES. It contains Clotrimazole (NA) + Choline Salicylate (NA), which Clotrimazole inhibits fungal cytochrome P450 14ฮฑ-demethylase, disrupting ergost. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clotrimazole + Choline Salicylate
  • Manufacturer: DWD Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š clenorush oral gel Uses & Benefits

Oral candidiasis, aphthous ulcers, denture stomatitis, oral inflammatory conditions

Off-label uses: Angular cheilitis, oral lichen planus

๐Ÿ“‹ Drug Information

Generic Name(s)Clotrimazole + Choline Salicylate
Brand NameClenorush Oral Gel
ManufacturerDWD Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntifungal + NSAID
Route of AdministrationTopical (oral gel)
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionClotrimazole: Poorly absorbed from oral mucosa; Choline Salicylate: Absorbed through oral mucosa
DistributionClotrimazole: Localized to oral cavity; Choline Salicylate: Distributed systemically
Protein BindingClotrimazole: 90-95%; Choline Salicylate: 80-90%
MetabolismClotrimazole: Hepatic via CYP3A4; Choline Salicylate: Hepatic via conjugation
Half-LifeClotrimazole: 3-6 hours; Choline Salicylate: 2-3 hours
ExcretionClotrimazole: Feces (biliary); Choline Salicylate: Renal
BioavailabilityClotrimazole: <1% systemic; Choline Salicylate: High via oral mucosa
Onset of ActionClotrimazole: 1-2 days; Choline Salicylate: 15-30 minutes
Peak Plasma TimeClotrimazole: Not applicable (local); Choline Salicylate: 1-2 hours
Duration of ActionClotrimazole: 3-4 hours; Choline Salicylate: 4-6 hours

How It Works

Clotrimazole inhibits fungal cytochrome P450 14ฮฑ-demethylase, disrupting ergosterol synthesis; Choline Salicylate inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis

Mechanism Steps

1Clotrimazole binds to fungal CYP51, inhibiting 14ฮฑ-demethylase
2Reduced ergosterol synthesis disrupts fungal cell membrane integrity
3Choline Salicylate inhibits COX-1 and COX-2 enzymes

๐Ÿ’ก How to Take clenorush oral gel

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clenorush oral gel

โœ… Common Side Effects

  • Bitter taste
  • Mild burning sensation
  • Nausea
  • Vomiting
  • Diarrhea

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Salicylate toxicity
  • Hepatotoxicity
  • Renal impairment
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Blood dyscrasias

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
Valproic Acid Major Increased valproate toxicity
ACE Inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
NSAIDs Moderate Increased GI side effects
Corticosteroids Moderate Increased GI ulceration risk
Aspirin Moderate Increased bleeding risk
Antacids Minor Reduced absorption of clotrimazole
Alcohol Minor Increased GI irritation
Caffeine Minor No significant interaction

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Anticoagulants
  • Lithium
  • Valproic Acid

โšก Moderate Interactions

  • ACE Inhibitors
  • Diuretics
  • NSAIDs
  • Corticosteroids
  • Aspirin

โ„น๏ธ Minor Interactions

  • Antacids
  • Alcohol
  • Caffeine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Increased risk of gastrointestinal irritation and bleeding

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, active GI bleeding, severe hepatic impairment, children <12 years (salicylate risk), third trimester of pregnancy

๐Ÿ“Š Monitoring Parameters

Oral lesion resolution, signs of salicylate toxicity (tinnitus, hyperventilation), liver function tests if prolonged use

๐Ÿคฑ Lactation Safety

Clotrimazole: Safe; Choline Salicylate: Use with caution

๐Ÿ’Š Overdose Management

Gastric lavage if ingested, supportive care, monitor for salicylate toxicity

โฐ Missed Dose

Apply as soon as remembered, skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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