dresin powder - Povidone Iodine (5% w/w) + Tinidazole (1% w/w) medicine

dresin powder

4.8 (8 reviews)
๐Ÿญ SAF Fermion Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is dresin powder used for?

Abdine Ointment (Povidone Iodine + Tinidazole) is used to treat DERMA. It contains Povidone Iodine (5% w/w) + Tinidazole (1% w/w), which Povidone iodine releases free iodine which oxidizes microbial proteins and enzym. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Povidone Iodine + Tinidazole
  • Manufacturer: SAF Fermion Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š dresin powder Uses & Benefits

Treatment of infected wounds, ulcers, burns; prevention of infection in minor cuts and abrasions; mixed infections including anaerobic bacteria and protozoa.

Off-label uses: Prevention of surgical site infections, Treatment of diabetic foot ulcers

๐Ÿ“‹ Drug Information

Generic Name(s)Povidone Iodine + Tinidazole
Brand NameAbdine Ointment
ManufacturerSAF Fermion Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntiseptic + Antiprotozoal
Route of AdministrationTopical.
StorageStore at room temperature (15-30ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption through intact skin; absorption may increase through broken skin or mucous membranes.
DistributionLimited distribution; mainly local at application site.
Protein BindingNot applicable for topical use.
MetabolismPovidone iodine releases iodine which is metabolized to iodide; tinidazole is metabolized in liver via CYP450.
Half-LifeNot applicable for topical use; systemic half-life of tinidazole is 12-14 hours.
ExcretionIodide excreted renally; tinidazole excreted in urine and feces.
BioavailabilityNegligible systemic bioavailability via topical route.
Onset of ActionRapid (within minutes for antiseptic effect).
Peak Plasma TimeNot applicable for topical use.
Duration of ActionUp to 24 hours with single application.

How It Works

Povidone iodine releases free iodine which oxidizes microbial proteins and enzymes, causing cell death. Tinidazole inhibits DNA synthesis in anaerobic bacteria and protozoa.

Mechanism Steps

1Povidone iodine complex dissociates on contact with skin, releasing free iodine.
2Free iodine penetrates microbial cell walls and oxidizes proteins, enzymes, and nucleic acids.
3Tinidazole enters microbial cells and undergoes reduction by bacterial nitroreductases.

๐Ÿ’ก How to Take dresin powder

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of dresin powder

โœ… Common Side Effects

  • Local irritation
  • Burning sensation
  • Dryness
  • Redness

๐Ÿšจ Serious Side Effects

  • Allergic contact dermatitis
  • Thyroid dysfunction (with prolonged use on large areas)
  • Metabolic acidosis (with systemic absorption)

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Acute generalized exanthematous pustulosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk due to inhibition of warfarin metabolism.
Lithium Major Possible lithium toxicity due to decreased renal clearance.
Disulfiram Moderate Psychotic reactions reported with concurrent use.
Alcohol Moderate Disulfiram-like reaction (nausea, vomiting, flushing).
Cimetidine Minor May increase tinidazole levels.

๐Ÿšจ Major Interactions

  • Warfarin
  • Lithium

โšก Moderate Interactions

  • Disulfiram
  • Alcohol

โ„น๏ธ Minor Interactions

  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Avoid alcohol during and 3 days after tinidazole treatment due to disulfiram-like reaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to iodine or tinidazole; thyroid disorders (e.g., Hashimoto's thyroiditis); use on large areas of broken skin or burns.

๐Ÿ“Š Monitoring Parameters

Monitor for signs of local irritation, allergic reactions, thyroid function in prolonged use.

๐Ÿคฑ Lactation Safety

Use with caution; iodine can be absorbed and excreted in breast milk; tinidazole excreted in breast

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, induce vomiting and seek medical attention; symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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