burnosaf plus cream - Silver Sulfadiazine (1% w/w) medicine

burnosaf plus cream

4.7 (14 reviews)
๐Ÿญ SAF Fermion Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is burnosaf plus cream used for?

Burnosaf Plus Cream (Silver Sulfadiazine) is used to treat DERMA. It contains Silver Sulfadiazine (1% w/w), which Silver ions bind to microbial DNA and cell wall, inhibiting replication and caus. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Silver Sulfadiazine
  • Manufacturer: SAF Fermion Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š burnosaf plus cream Uses & Benefits

Prevention and treatment of wound infections in second- and third-degree burns.

Off-label uses: Treatment of chronic wounds, pressure ulcers, diabetic foot ulcers.

๐Ÿ“‹ Drug Information

Generic Name(s)Silver Sulfadiazine
Brand NameBurnosaf Plus Cream
ManufacturerSAF Fermion Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassSulphonamides
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption through intact skin; absorption increases with damaged skin or burns.
DistributionDistributes locally in skin; systemic distribution negligible.
Protein BindingNot applicable due to minimal systemic absorption.
MetabolismNot significantly metabolized systemically.
Half-LifeNot applicable due to minimal systemic absorption.
ExcretionExcreted primarily in urine if absorbed, but negligible.
BioavailabilityNegligible systemic bioavailability.
Onset of ActionRapid local effect; within hours.
Peak Plasma TimeNot applicable due to minimal systemic absorption.
Duration of Action12-24 hours after application.

How It Works

Silver ions bind to microbial DNA and cell wall, inhibiting replication and causing cell death.

Mechanism Steps

1Silver ions dissociate from sulfadiazine in wound exudate.
2Silver ions bind to microbial DNA and cell wall proteins.
3Inhibition of microbial replication and cell wall synthesis.

๐Ÿ’ก How to Take burnosaf plus cream

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of burnosaf plus cream

โœ… Common Side Effects

  • Local burning
  • itching
  • rash

๐Ÿšจ Serious Side Effects

  • Leukopenia
  • Stevens-Johnson syndrome
  • Renal toxicity

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cimetidine Major Increased risk of silver toxicity
Probenecid Major Decreased renal excretion of silver
Topical enzymes Major Inactivation of enzymes
Anticoagulants Moderate Potential increased anticoagulant effect
Oral hypoglycemics Moderate Potential enhanced hypoglycemic effect

๐Ÿšจ Major Interactions

  • Cimetidine
  • Probenecid
  • Topical enzymes

โšก Moderate Interactions

  • Anticoagulants
  • Oral hypoglycemics

โ„น๏ธ Minor Interactions

  • None known

๐Ÿฝ๏ธ Food Interactions

None known

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to silver sulfadiazine or sulfonamides; pregnant women at term; premature infants; neonates.

๐Ÿ“Š Monitoring Parameters

Monitor for signs of infection, allergic reactions, renal function in extensive burns.

๐Ÿคฑ Lactation Safety

Caution; minimal systemic absorption but avoid application to breast area.

๐Ÿ’Š Overdose Management

Unlikely due to topical use; if ingested, symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for burnosaf plus cream

View All

Alternative brands with exact same active ingredient (Silver Sulfadiazine (1% w/w)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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