dothitab 25mg tablet - Uses, Price, Side Effects & Substitutes
What is dothitab 25mg tablet used for?
Arpin 25mg Tablet (Dosulepin) is used to treat NEURO CNS. It contains Dosulepin (25mg), which Increases the levels of serotonin and norepinephrine in the synaptic cleft by in. Always consult your doctor before use. Take as prescribed.
- Generic Name: Dosulepin
- Manufacturer: Psycormedies
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ dothitab 25mg tablet Uses & Benefits
Major depressive disorder, anxiety disorders, neuropathic pain.
Off-label uses: Insomnia, chronic pain, migraine prophylaxis.
๐ Drug Information
| Generic Name(s) | Dosulepin |
| Brand Name | Arpin 25mg Tablet |
| Manufacturer | Psycormedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Tricyclic antidepressants |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Increases the levels of serotonin and norepinephrine in the synaptic cleft by inhibiting their reuptake.
Mechanism Steps
๐ก How to Take dothitab 25mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dothitab 25mg tablet
โ Common Side Effects
- Dry mouth
- Sedation
- Constipation
- Blurred vision
- Urinary retention
๐จ Serious Side Effects
- QT prolongation
- Seizures
- Serotonin syndrome
- Suicidal ideation
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Hepatitis
- Hypomania
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Risk of serotonin syndrome |
| Linezolid | Major | Risk of serotonin syndrome |
| Methylene blue | Major | Risk of serotonin syndrome |
| CNS depressants | Moderate | Increased sedation |
| Anticholinergics | Moderate | Additive anticholinergic effects |
| Sympathomimetics | Moderate | Risk of hypertension |
| Cimetidine | Minor | Increased dosulepin levels |
| Fluoxetine | Minor | Increased dosulepin levels |
| Paroxetine | Minor | Increased dosulepin levels |
๐จ Major Interactions
- MAOIs
- Linezolid
- Methylene blue
โก Moderate Interactions
- CNS depressants
- Anticholinergics
- Sympathomimetics
โน๏ธ Minor Interactions
- Cimetidine
- Fluoxetine
- Paroxetine
๐ฝ๏ธ Food Interactions
Avoid alcohol; may increase sedation.
๐ท Alcohol Interaction
Enhanced CNS depression; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Recent myocardial infarction, arrhythmias, severe liver disease, mania, hypersensitivity.
๐ Monitoring Parameters
ECG, liver function tests, blood pressure, mental status.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Supportive care; activated charcoal, ECG monitoring, sodium bicarbonate for arrhythmias.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip if close to next dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for dothitab 25mg tablet
View AllAlternative brands with exact same active ingredient (Dosulepin (25mg)):
-
othipen 25mg tabletZee Laboratories โน13.13 45.9% CHEAPER
-
exodep 25mg tabletSun Pharmaceutical Industries Ltd โน14.14 41.8% CHEAPER
-
elden 25mg tabletElite Pharma Pvt Ltd โน15.94 34.3% CHEAPER
-
zedip 25mg tabletZenith Healthcare Ltd โน17.58 27.6% CHEAPER
-
druthip 25mg tabletLifecare Innovations Pvt Ltd โน17.81 26.6% CHEAPER
-
thipin 25mg tabletVGR Bio Lab โน17.81 26.6% CHEAPER
-
trisun 25mg tabletSunrise Remedies Pvt Ltd โน18.75 22.8% CHEAPER
-
arpin 25mg tabletRKG Pharma โน20.63 15% CHEAPER
-
dothivin 25mg tabletKelvin Pharmaceutical Laboratories Pvt Ltd โน20.63 15% CHEAPER
-
dotipin 25mg tabletCyril Pharmaceuticals โน20.63 15% CHEAPER
Medical Note: Always consult your doctor before switching medications.