dorikem 500mg kit - Doripenem (500mg) medicine

dorikem 500mg kit

4.4 (14 reviews)
๐Ÿญ Alkem Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is dorikem 500mg kit used for?

Carbador (Doripenem) is used to treat ANTI INFECTIVES. It contains Doripenem (500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Doripenem
  • Manufacturer: Alkem Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š dorikem 500mg kit Uses & Benefits

Complicated intra-abdominal infections, complicated urinary tract infections, nosocomial pneumonia.

Off-label uses: Febrile neutropenia, Bacterial meningitis

๐Ÿ“‹ Drug Information

Generic Name(s)Doripenem
Brand NameCarbador
ManufacturerAlkem Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCell wall active agent -Carbapenems
Route of AdministrationIntravenous
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability.
DistributionWidely distributed into tissues and body fluids, including lung, bile, and CSF.
Protein BindingApproximately 8-9%
MetabolismPrimarily metabolized by dehydropeptidase-I to an inactive metabolite.
Half-LifeApproximately 1 hour
ExcretionPrimarily excreted unchanged in urine (70-80%) via glomerular filtration and tubular secretion.
Bioavailability100% (intravenous)
Onset of ActionRapid (within 30 minutes)
Peak Plasma TimeEnd of infusion
Duration of ActionApproximately 8 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis.

Mechanism Steps

1Doripenem binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall.
2Inhibition of transpeptidase activity prevents cross-linking of peptidoglycan chains.
3Autolytic enzymes are activated, leading to cell wall degradation and bacterial lysis.

๐Ÿ’ก How to Take dorikem 500mg kit

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of dorikem 500mg kit

โœ… Common Side Effects

  • Headache
  • Nausea
  • Diarrhea
  • Phlebitis at injection site

๐Ÿšจ Serious Side Effects

  • Seizures
  • Anaphylaxis
  • Clostridioides difficile colitis

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Probenecid Major Decreased renal clearance of doripenem, increased plasma levels
Valproic acid Major Decreased valproic acid levels, increased seizure risk
Aminoglycosides Moderate Additive nephrotoxicity
Loop diuretics Moderate Increased nephrotoxicity risk

๐Ÿšจ Major Interactions

  • Probenecid
  • Valproic acid

โšก Moderate Interactions

  • Aminoglycosides
  • Loop diuretics

โ„น๏ธ Minor Interactions

  • Oral contraceptives

๐Ÿฝ๏ธ Food Interactions

None known

๐Ÿท Alcohol Interaction

No specific interaction reported

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to doripenem or other carbapenems, anaphylactic reactions to beta-lactams.

๐Ÿ“Š Monitoring Parameters

Renal function, signs of hypersensitivity, superinfection, and bleeding.

๐Ÿคฑ Lactation Safety

Caution advised; excreted in breast milk in small amounts.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Administer as soon as possible; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for dorikem 500mg kit

View All

Alternative brands with exact same active ingredient (Doripenem (500mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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