dologen tablet
What is dologen tablet used for?
Anadol P (Tramadol + Paracetamol) is used to treat PAIN ANALGESICS. It contains Tramadol (37.5mg) + Paracetamol (325mg), which Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reu. Always consult your doctor before use. Take as prescribed.
- Generic Name: Tramadol + Paracetamol
- Manufacturer: Zerico Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ dologen tablet Uses & Benefits
Moderate to severe pain, acute pain, postoperative pain
Off-label uses: Chronic pain, neuropathic pain
๐ Drug Information
| Generic Name(s) | Tramadol + Paracetamol |
| Brand Name | Anadol P |
| Manufacturer | Zerico Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Opioid analgesic + Non-opioid analgesic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reuptake; Paracetamol: Inhibits COX enzymes in the CNS, reducing prostaglandin synthesis
Mechanism Steps
๐ก How to Take dologen tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dologen tablet
โ Common Side Effects
- Nausea
- Dizziness
- Drowsiness
- Constipation
- Headache
- Sweating
๐จ Serious Side Effects
- Respiratory depression
- Seizures
- Serotonin syndrome
- Hepatotoxicity
- Hypotension
โ ๏ธ Rare Side Effects
- QT prolongation
- Adrenal insufficiency
- Anaphylaxis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Risk of serotonin syndrome |
| SSRIs | Major | Increased serotonin levels, risk of serotonin syndrome |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Alcohol | Moderate | Enhanced CNS depression and hepatotoxicity |
๐จ Major Interactions
- MAOIs
- SSRIs
- SNRIs
- TCAs
- CNS depressants
- Carbamazepine
- Rifampin
โก Moderate Interactions
- Warfarin
- Anticoagulants
- Alcohol
- Antiepileptics
- CYP2D6 inhibitors
โน๏ธ Minor Interactions
- Cimetidine
- Metoclopramide
๐ฝ๏ธ Food Interactions
No significant food interactions; avoid grapefruit juice (CYP3A4 inhibition)
๐ท Alcohol Interaction
Increased CNS depression and hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, acute opioid intoxication, severe respiratory depression, MAOI use within 14 days, severe hepatic impairment
๐ Monitoring Parameters
Pain relief, respiratory rate, liver function, renal function, signs of serotonin syndrome
๐คฑ Lactation Safety
Use with caution; tramadol excreted in breast milk
๐ Overdose Management
Naloxone for tramadol; N-acetylcysteine for paracetamol; supportive care
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.