dinfla gel - Diclofenac (NA) medicine

Activa Plus Tablet: Comprehensive Medicine Guide

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🏭 Wanbury Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Avoid use in the third trimester due to risk of premature closure of the ductus arteriosus. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising
  • Severe dizziness or fainting

If experiencing severe symptoms, call emergency services immediately.

What is dinfla gel used for?

This medicine is a non-steroidal anti-inflammatory drug (NSAID) containing diclofenac. It is used to relieve pain, swelling, and stiffness in conditions like arthritis, gout, and musculoskeletal injuries. It works by blocking COX enzymes and reducing prostaglandins. Take it with food to avoid stomach upset.

  • Generic Name: Diclofenac (NA)
  • Manufacturer: Wanbury Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dinfla gel के बारे में (Hindi Summary)

उपयोग: यह दवा डाइक्लोफेनाक नामक सक्रिय तत्व वाली एक प्रिस्क्रिप्शन दर्द निवारक और सूजन-रोधी दवा है। यह गठिया, जोड़ों के दर्द, सूजन, अकड़न, गाउट, और मांसपेशियों की चोटों में राहत देने के लिए इस्तेमाल की जाती है। यह शरीर में प्रोस्टाग्लैंडिन नामक रसायनों को कम करके दर्द और सूजन को कम करती है। इसे डॉक्टर के निर्देशानुसार ही लें। इसे खाने के साथ लें ताकि पेट में जलन न हो। गर्भवती महिलाओं, दिल, किडनी या लीवर की बीमारी वाले मरीजों को इसका सेवन डॉक्टर की सलाह के बिना नहीं करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट दर्द, जलन, मतली, उल्टी, दस्त, कब्ज, सिरदर्द, चक्कर आना और त्वचा पर हल्के दाने शामिल हैं। ये आमतौर पर हल्के होते हैं और ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन हो सकते हैं, जैसे पेट में रक्तस्राव, किडनी या लीवर की समस्या, गंभीर एलर्जी, और दिल का दौरा। अगर आपको काला मल, खून की उल्टी, सांस लेने में तकलीफ, या चेहरे पर सूजन हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा खाने या दूध के साथ लें ताकि पेट में जलन न हो। निर्धारित मात्रा से ज्यादा न लें और डॉक्टर की सलाह के बिना लंबे समय तक न लें। इस दवा के साथ शराब न पिएं। अगर आपको पेट के अल्सर, दिल, किडनी या लीवर की बीमारी है, तो डॉक्टर को बताएं। गर्भावस्था, स्तनपान या गर्भधारण की योजना बनाते समय डॉक्टर से सलाह लें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। चक्कर आने पर वाहन न चलाएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 dinfla gel Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps relieve back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute gout","description":"Provides rapid relief from pain and inflammation during acute gout attacks.","evidence":"Well-established"},{"condition":"Musculoskeletal injuries","description":"Used for short-term relief of pain and swelling in sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"May be used to manage mild to moderate pain after surgery.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Pericarditis","description":"May be used off-label for pain and inflammation in pericarditis, under specialist care.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation associated with musculoskeletal and joint conditions

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute gout, Dysmenorrhea, Postoperative pain

📋 Drug Information

Generic Name(s)Diclofenac (NA)
Brand Namedinfla gel
ManufacturerWanbury Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Use the lowest effective dose for the shortest duration to minimize side effects.
3
Avoid alcohol while taking this medicine to prevent stomach bleeding.
4
Do not take other NSAIDs concurrently without consulting your doctor.
5
If you have a history of stomach ulcers, heart disease, or kidney problems, inform your doctor before starting this medicine.
6
Report any unusual bleeding, bruising, or black stools immediately.
7
Stay well hydrated throughout the day to support kidney function.
8
Do not drive or operate heavy machinery if you experience dizziness.
9
Consult your doctor if pain persists beyond 7 days or worsens.
10
Keep a record of your symptoms to help your doctor assess the effectiveness of the treatment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Acute gout
This medicine is used for acute gout attacks.
Likely Use
Menstrual cramps
This medicine can relieve dysmenorrhea.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and completely absorbed from the gastrointestinal tract after oral administration. Food may delay the rate but not the extent of absorption. Peak plasma concentrations are typically reached within 1 to 2 hours after ingestion.
DistributionThis medicine is highly bound to plasma proteins, primarily albumin. It distributes widely into body tissues, including synovial fluid, where it can reach concentrations comparable to plasma levels. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingGreater than 99% bound to plasma proteins, mainly albumin.
MetabolismThis medicine undergoes extensive hepatic metabolism, primarily by cytochrome P450 enzymes, including CYP2C9. It is metabolized to several hydroxylated metabolites, which are then conjugated and excreted.
Half-LifeThe elimination half-life of this medicine is approximately 1 to 2 hours. However, the therapeutic effect may last longer due to tissue distribution.
ExcretionThis medicine and its metabolites are excreted primarily in the urine (about 65%) and bile/feces (about 35%).
BioavailabilityThe oral bioavailability of this medicine is approximately 50% to 60% due to first-pass metabolism.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 1 to 2 hours after oral intake.
Duration of ActionThe analgesic and anti-inflammatory effects of this medicine usually last for 4 to 6 hours, although the anti-inflammatory effect may persist longer with regular dosing.

How It Works

This medicine works by inhibiting the cyclooxygenase enzymes, primarily COX-1 and COX-2, which are responsible for converting arachidonic acid into prostaglandins and thromboxane. Prostaglandins are chemicals that promote pain, inflammation, and fever. By blocking their production, this medicine reduces pain, swelling, and stiffness. The inhibition is reversible and non-selective, meaning it affects both COX-1 and COX-2 enzymes. This dual inhibition explains both its therapeutic effects and some of its side effects, such as stomach irritation and increased bleeding risk.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: This medicine binds reversibly to both COX-1 and COX-2 enzymes, preventing them from converting arachidonic acid into prostaglandin H2.
2
Reduced prostaglandin synthesis: As a result of COX inhibition, the production of prostaglandins, prostacyclin, and thromboxane is decreased.
3
Decreased pain and inflammation: Lower levels of prostaglandins lead to reduced sensitization of pain receptors and less vasodilation and edema at sites of injury.
4
Antipyretic effect: Prostaglandin reduction in the hypothalamus helps reset the body's temperature set point, reducing fever.
5
Platelet effects: Inhibition of thromboxane A2 production in platelets impairs platelet aggregation, which can increase bleeding risk.

💡 How to Take dinfla gel

Strength: This medicine is available as an immediate-release tablet. The strength is not specified in the provided information.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it with food or milk to reduce stomach upset.
4Do not crush, chew, or break the tablet unless instructed.
5Take it at the same times each day to maintain consistent levels.
6Do not take more than the prescribed dose.
7If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 50 mg two to three times daily, or 75 mg two times daily, depending on the condition being treated. For acute gout, a higher initial dose may be used. The maximum daily dose is generally 150 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine and are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with mild to moderate kidney impairment, no dose adjustment is usually necessary, but caution is advised. In severe kidney impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with mild to moderate liver impairment, no dose adjustment is usually necessary, but caution is advised. In severe liver impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician.
Maximum Daily Dose150 mg per day in divided doses.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dinfla gel

✅ Common Side Effects

Stomach pain or heartburn (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Nausea (Common (5-10%))
Take with food. If vomiting occurs, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Diarrhea or constipation (Common (5-10%))
Stay hydrated. Consult doctor if severe or persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding or ulceration (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver damage (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, or throat, or difficulty breathing.
Cardiovascular events (heart attack, stroke) (Rare (<0.1%))
Seek immediate medical help if you experience chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, or sensitivity to light.
Pancreatitis
Seek immediate medical attention if you experience severe upper abdominal pain radiating to the back.
Severe skin reactions (Stevens-Johnson syndrome)
Stop the medicine and seek immediate medical help if you develop a rash with blisters or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
Diuretics Moderate
SSRIs Moderate
Antacids Minor
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • ACE inhibitors and ARBs
  • Diuretics
  • Beta-blockers
  • SSRIs

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of stomach bleeding, ulcers, and liver problems. It may also worsen dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney impairment","Severe liver impairment","Allergy to diclofenac or other NSAIDs","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Third trimester of pregnancy","Coronary artery bypass graft (CABG) surgery perioperative period"]

⚠️ Warnings & Precautions

["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use for longer than prescribed without medical advice.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, heart disease, kidney or liver disease.","Do not drive or operate machinery if you feel dizzy or drowsy.","This medicine may increase the risk of serious cardiovascular events.","Do not use this medicine if you are pregnant or planning pregnancy without consulting your doctor."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. It is generally considered safe for short-term use during breastfeeding, but consult your doctor before use. Monitor the infant for any unusual symptoms.

💊 Overdose Management

Overdose of this medicine can cause symptoms such as severe abdominal pain, vomiting, bleeding, drowsiness, and kidney failure. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and may include activated charcoal, gastric lavage, and monitoring of vital signs and kidney function. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine with food or milk to reduce the chance of stomach upset. Do not take more than the prescribed dose or for longer than recommended. Avoid alcohol while taking this medicine, as it can increase the risk of stomach bleeding. If you have a history of stomach ulcers, heart disease, kidney problems, or liver disease, inform your doctor before starting this medicine. Do not use this medicine if you are allergic to diclofenac, aspirin, or other NSAIDs. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. This medicine may interact with blood thinners, blood pressure medicines, and other pain relievers. Always tell your doctor about all medicines you are taking. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Store this medicine at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly. Avoid concurrent use with other NSAIDs or blood thinners unless directed by a doctor.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. NSAIDs like this medicine may interfere with ovulation and are generally avoided during conception and early pregnancy. Use alternative pain relief options as advised by your doctor.

🏥 Post-Surgery Considerations

After surgery, this medicine may be used for pain management, but it can increase the risk of bleeding. Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before certain surgeries. Follow your doctor's instructions carefully.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure, as it can increase the risk of bleeding. Your dentist may advise you to stop it temporarily before surgery. Do not stop without consulting your doctor.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture to prevent back and neck pain.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables in your diet.
🧘
Get adequate sleep to help your body recover.
🌞
Manage stress through relaxation techniques like yoga or meditation.

🏋️ Exercise Considerations

While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Low-impact exercises like swimming or walking are generally safe, but consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Stay well hydrated by drinking plenty of water.
Eat a balanced diet rich in fruits and vegetables.
Limit alcohol consumption.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. If your work involves physical labor, consult your doctor about modifications. Generally, it helps improve pain and mobility, allowing you to perform daily activities more comfortably.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor immediately if you experience serious side effects such as black stools, vomiting blood, severe abdominal pain, chest pain, difficulty breathing, or signs of an allergic reaction. Do not stop taking this medicine abruptly if you have been on long-term therapy without consulting your doctor, as your condition may worsen.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver damage, and cardiovascular events such as heart attack and stroke. Regular monitoring of kidney and liver function, blood pressure, and signs of bleeding is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor regularly to assess the need for continued therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Heat and cold therapy

Applying heat or cold packs can help reduce pain and inflammation.

Evidence: Well-established
Acupuncture

May provide pain relief for some individuals.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, if you are scheduled for vaccination, inform your healthcare provider that you are taking this medicine. It is generally safe to receive vaccines while on this medicine, but consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking it as prescribed, but consult your doctor if you need to adjust the timing. Check customs regulations for carrying prescription medicines. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with acute gout attack
Experienced severe pain and swelling in his big toe. His doctor prescribed this medicine. He took it with food and noticed relief within a few hours. He was advised to avoid alcohol and follow up for monitoring.
💡 Lesson: Prompt use of this medicine during a gout attack can provide rapid relief, but lifestyle modifications and monitoring are essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other pain relievers?

A: Do not take other NSAIDs concurrently without consulting your doctor, as it increases the risk of side effects.

Q: Can I take it if I am pregnant?

A: Consult your doctor before taking this medicine during pregnancy, especially in the third trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for dinfla gel

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a steroid.
    Fact: This medicine is a non-steroidal anti-inflammatory drug (NSAID), not a steroid.
  • Myth: This medicine can be taken on an empty stomach.
    Fact: This medicine should be taken with food or milk to reduce stomach upset.
  • Myth: This medicine is safe to take indefinitely without monitoring.
    Fact: Long-term use requires monitoring of kidney and liver function and may increase cardiovascular risk.
  • Myth: This medicine can be taken with other pain relievers without risk.
    Fact: Combining with other NSAIDs increases the risk of side effects and should be avoided unless directed by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac sodium

Brand Alternatives

  • Voveran
  • Voltaren
  • Cataflam

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"NSAID","half_life":"1-2 hours","common_uses":"Arthritis, gout, musculoskeletal pain"},{"medicine":"Ibuprofen","class":"NSAID","half_life":"2-4 hours","common_uses":"Pain, fever, inflammation"},{"medicine":"Naproxen","class":"NSAID","half_life":"12-17 hours","common_uses":"Arthritis, pain, inflammation"}]

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