Clovolac 500mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe dizziness or fainting
- Rapid heartbeat or palpitations
If experiencing severe symptoms, call emergency services immediately.
What is diasdac-er tablet used for?
This medicine is a prescription NSAID containing Etodolac 500 mg, used to relieve pain and inflammation in conditions like osteoarthritis and rheumatoid arthritis. It works by selectively inhibiting COX-2 enzymes. Take it with food to reduce stomach upset, and avoid alcohol. Do not use it if you have active ulcers, severe kidney or liver disease, or are in late pregnancy.
- Generic Name: Etodolac
- Manufacturer: Jupiter Biolabs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 diasdac-er tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोडोलैक 500 मिलीग्राम युक्त एक प्रिस्क्रिप्शन ओरल टैबलेट है, जिसका उपयोग ऑस्टियोआर्थराइटिस और रूमेटॉइड आर्थराइटिस जैसी स्थितियों में जोड़ों के दर्द, सूजन और अकड़न को कम करने के लिए किया जाता है। यह एक नॉनस्टेरॉइडल एंटी-इंफ्लेमेटरी ड्रग (NSAID) है जो शरीर में सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। यह दवा अल्सर, गुर्दे या यकृत की गंभीर बीमारी, या गर्भावस्था के अंतिम चरण में नहीं लेनी चाहिए। इसे हमेशा डॉक्टर के परामर्श से ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट खराब होना, जी मिचलाना, सिरदर्द, चक्कर आना, दस्त या कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट या आंतों में रक्तस्राव, दिल का दौरा, स्ट्रोक, गुर्दे की समस्या और यकृत विषाक्तता शामिल हो सकते हैं। यदि आपको काला मल, उल्टी में खून, तेज पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। शराब का सेवन न करें क्योंकि इससे रक्तस्राव का खतरा बढ़ सकता है। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे, यकृत, या हृदय की समस्या है, तो डॉक्टर को बताएं। लंबे समय तक उपयोग के दौरान नियमित जांच कराएं।
💊 diasdac-er tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in joints affected by osteoarthritis, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation, and swelling associated with rheumatoid arthritis, helping to maintain joint function.","evidence":"Well-established"},{"condition":"Juvenile idiopathic arthritis","description":"May be used in children above a certain age under specialist supervision for juvenile idiopathic arthritis.","evidence":"Limited"},{"condition":"Acute pain","description":"Short-term management of mild to moderate acute pain, such as musculoskeletal pain or post-operative pain.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain in some women.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, though evidence is limited.","evidence":"Limited"},{"condition":"Ankylosing spondylitis","description":"May be used off-label to reduce pain and stiffness in ankylosing spondylitis.","evidence":"Limited"},{"condition":"Bursitis and tendinitis","description":"Occasionally used off-label for inflammatory conditions of bursae and tendons.","evidence":"Limited"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Juvenile idiopathic arthritis, Acute pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Etodolac |
| Brand Name | Arthadol 400mg Tablet |
| Manufacturer | Jupiter Biolabs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme, which is responsible for producing prostaglandins that cause pain and inflammation. By blocking COX-2, it reduces the levels of these inflammatory mediators at the site of injury or inflammation. Unlike non-selective NSAIDs, it has less effect on COX-1, which helps protect the stomach lining, potentially reducing gastrointestinal side effects. However, it still carries some risk of stomach irritation and bleeding. The analgesic and anti-inflammatory effects are achieved without significantly affecting platelet function or bleeding time in most individuals.
Mechanism Steps
💡 How to Take diasdac-er tablet
Strength: 500 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for osteoarthritis and rheumatoid arthritis is 300 mg to 500 mg taken orally two to three times daily, not to exceed 1000 mg per day. For acute pain, a dose of 200 mg to 400 mg every 6 to 8 hours may be used as needed, with a maximum of 1000 mg per day. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Always follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal and cardiovascular side effects. The lowest effective dose should be used for the shortest duration. Dose adjustment may be necessary based on kidney and liver function. Consult your doctor for appropriate dosing. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no dose adjustment is usually necessary. However, in severe kidney impairment (creatinine clearance less than 30 mL/min), this medicine is not recommended. Consult your doctor for dose adjustment and monitoring. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, no dose adjustment is usually necessary. In severe liver impairment, this medicine is not recommended. Consult your doctor for dose adjustment and monitoring. |
| Maximum Daily Dose | 1000 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of diasdac-er tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Corticosteroids
- Lithium
- Methotrexate
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Beta-blockers
- SSRIs
- Cyclosporine
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulceration, and liver toxicity. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Etodolac or other NSAIDs","Active peptic ulcer or history of recurrent peptic ulcer","Active gastrointestinal bleeding or history of bleeding disorders","Severe kidney impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["This medicine may increase the risk of serious cardiovascular events. Use with caution in patients with heart disease, high blood pressure, or risk factors for heart disease.","Gastrointestinal bleeding, ulceration, and perforation can occur at any time without warning. Use with caution in patients with a history of ulcer or bleeding.","Kidney function may be impaired. Use with caution in patients with kidney disease, dehydration, or those taking diuretics or ACE inhibitors.","Liver function may be affected. Monitor liver enzymes during long-term use.","This medicine may cause fluid retention and edema. Use with caution in patients with heart failure or hypertension.","May cause drowsiness or dizziness. Avoid driving or operating machinery until you know how it affects you.","Do not use this medicine for pain relief before or after CABG surgery.","Elderly patients are at higher risk of serious gastrointestinal and cardiovascular side effects. Use the lowest effective dose.","This medicine may mask signs of infection, such as fever.","Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
This medicine is excreted in breast milk. Consult your doctor before using this medicine while breastfeeding. Alternative medications may be preferred.
💊 Overdose Management
Overdose of this medicine may cause symptoms such as severe abdominal pain, nausea, vomiting, drowsiness, and gastrointestinal bleeding. In case of suspected overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be administered if the overdose is recent. Monitor vital signs, kidney function, and liver function. Hemodialysis is not effective for removing this medicine from the body.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take each dose with a full glass of water and preferably with food or milk to minimize stomach upset. Avoid alcohol while taking this medicine, as it can increase the risk of gastrointestinal bleeding. Do not take other NSAIDs, including over-the-counter pain relievers like ibuprofen or naproxen, without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, heart disease, high blood pressure, kidney or liver problems, or asthma. This medicine may interact with blood thinners, antidepressants, diuretics, and certain blood pressure medications. Regular monitoring of kidney function, liver function, and blood counts may be required during long-term therapy. If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor before using this medicine. Do not drive or operate heavy machinery if you experience dizziness or drowsiness. Store this medicine at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Regular monitoring of kidney and liver function is recommended. Avoid concomitant use of other NSAIDs or blood thinners.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may affect ovulation and implantation. Avoid use during pregnancy, especially in the third trimester, unless clearly needed and prescribed by a doctor.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain management under medical supervision. However, it is contraindicated before or after coronary artery bypass graft (CABG) surgery. Inform your surgeon about all medications you are taking before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. This medicine may increase the risk of bleeding during dental work. Your dentist may advise temporary discontinuation or adjust your treatment plan.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may engage in light to moderate exercise as tolerated. However, avoid high-impact activities that can strain your joints. If you experience dizziness or drowsiness, avoid exercises that require balance or coordination. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some individuals. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take regular breaks and maintain good posture. Inform your employer if you need any accommodations.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as gastrointestinal bleeding, chest pain, or allergic reactions, seek immediate medical attention. Your doctor may advise stopping the medicine or switching to an alternative based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of serious cardiovascular events, gastrointestinal bleeding, kidney impairment, and liver toxicity. Regular monitoring of kidney function, liver function, and blood counts is recommended. Use the lowest effective dose for the shortest duration possible. Discuss with your doctor if you need to use this medicine for more than a few weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedReducing weight can decrease stress on joints and improve symptoms of osteoarthritis.
Evidence: Well-establishedMay help relieve chronic pain in some patients.
Evidence: ModerateMay provide localized pain relief with fewer systemic side effects.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust your dosing schedule gradually to avoid missing doses. Check local customs regulations regarding prescription medications. Always carry enough supply for your entire trip, and keep it in your carry-on luggage if flying. Inform airport security about your medication if necessary.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 30 to 60 minutes after oral administration. Peak effects occur within 1 to 2 hours.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset and gastrointestinal irritation.
A: Long-term use should be under strict medical supervision. Regular monitoring of kidney and liver function, as well as blood counts, is recommended. Use the lowest effective dose for the shortest duration.
A: No, alcohol should be avoided while taking this medicine as it increases the risk of gastrointestinal bleeding and liver toxicity.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Yes, this medicine can interact with blood thinners like warfarin, increasing the risk of bleeding. Inform your doctor if you are taking blood thinners.
A: This medicine should be avoided during pregnancy, especially in the third trimester, unless clearly needed and prescribed by a doctor. Consult your doctor for guidance.
A: This medicine may not be safe for patients with severe kidney disease. Consult your doctor for dose adjustment and monitoring.
🤔 Common Patient Concerns
🔄 Substitutes for diasdac-er tablet
View AllAlternative brands with exact same active ingredient:
-
etura 500mg tabletDr Reddy's Laboratories Ltd ₹105.00 52.3% CHEAPER
-
etoswift 500mg tablet erOrchid Chemicals & Pharmaceuticals Ltd ₹107.81 51.1% CHEAPER
-
etobling 500mg tablet erNusmith Pharma Pvt. Ltd ₹139.69 36.6% CHEAPER
-
clovolac 500mg tabletMediclove Biotech Pvt Ltd ₹156.50 29% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a steroid.
Fact: This medicine is a nonsteroidal anti-inflammatory drug (NSAID), not a steroid. It does not contain corticosteroids. - Myth: This medicine can cure arthritis.
Fact: This medicine helps manage pain and inflammation but does not cure arthritis. It is used for symptomatic relief. - Myth: This medicine is safe to take on an empty stomach.
Fact: This medicine should be taken with food or milk to reduce the risk of stomach upset and gastrointestinal bleeding. - Myth: This medicine can be taken with other pain relievers without any risk.
Fact: Taking this medicine with other NSAIDs can increase the risk of serious side effects. Always consult your doctor before combining pain relievers.
🔄 Alternative Options
Generic Alternatives
- Etodolac 500 mg tablet
Brand Alternatives
- Clovolac 500mg Tablet