Ocupol DX Eye Ointment: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden vision loss or severe eye pain
- Swelling of the face, lips, or throat, or difficulty breathing
- Severe eye redness or discharge that worsens
- Eye injury or foreign body in the eye
- Signs of allergic reaction such as rash, itching, or hives
- Unusual tiredness, pale skin, easy bruising, or fever
- Increased eye pressure symptoms like halos around lights or headaches
If experiencing severe symptoms, call emergency services immediately.
What is dexa pc eye drop used for?
This medicine is an eye ointment that combines an antibiotic (chloramphenicol) and a steroid (dexamethasone) to treat bacterial eye infections with inflammation. It is applied inside the lower eyelid as directed by a doctor. It should not be used for viral or fungal eye infections.
- Generic Name: Chloramphenicol (10mg) + Dexamethasone (1mg)
- Manufacturer: Calibre Pharmaceutical
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dexa pc eye drop के बारे में (Hindi Summary)
उपयोग: यह दवा एक आंखों की मरहम है जिसमें क्लोरैम्फेनिकॉल (एक एंटीबायोटिक) और डेक्सामेथासोन (एक स्टेरॉयड) शामिल हैं। यह बैक्टीरियल आंखों के संक्रमण के इलाज के लिए इस्तेमाल की जाती है जिसमें सूजन, लालिमा और दर्द भी होता है। यह आंखों की सूजन को कम करने और बैक्टीरिया को मारने में मदद करती है। इसे डॉक्टर के निर्देशानुसार आंख की निचली पलक के अंदर लगाया जाता है। यह दवा वायरल, फंगल या पैरासाइटिक आंखों के संक्रमण के लिए नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मरहम लगाने के बाद धुंधली दृष्टि, हल्की जलन, आंखों में खुजली या लालिमा शामिल हैं। कुछ लोगों को आंखों में कुछ महसूस हो सकता है। गंभीर दुष्प्रभावों में आंखों का बढ़ा हुआ दबाव, मोतियाबिंद, और दूसरा संक्रमण शामिल हैं। लंबे समय तक उपयोग से ये जोखिम बढ़ सकते हैं। यदि आंखों में तेज दर्द, दृष्टि में बदलाव, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा का उपयोग केवल अपने नेत्र रोग विशेषज्ञ के निर्देशानुसार करें। लगाने से पहले और बाद में हाथ धोएं। ट्यूब की नोक को आंख या किसी सतह से न छुएं। निर्धारित मात्रा से अधिक या लंबे समय तक उपयोग न करें। आंखों में लगाने के बाद कुछ मिनट तक धुंधली दृष्टि हो सकती है, इसलिए तब तक वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को ठंडी और सूखी जगह पर रखें।
💊 dexa pc eye drop Uses & Benefits
[{"condition":"Bacterial conjunctivitis with inflammation","description":"This medicine is used to treat bacterial infection of the conjunctiva when inflammation and redness are also present.","evidence":"Well-established"},{"condition":"Bacterial blepharitis","description":"It helps control bacterial infection of the eyelids and reduces associated swelling and irritation.","evidence":"Well-established"},{"condition":"Bacterial keratitis with inflammation","description":"It may be used for certain bacterial corneal infections when a doctor decides that the anti-inflammatory effect is needed.","evidence":"Limited"},{"condition":"Post-operative eye inflammation and infection prevention","description":"Sometimes prescribed after eye surgery to prevent bacterial infection and reduce post-surgical inflammation.","evidence":"Limited"},{"condition":"Ocular inflammation with suspected bacterial infection","description":"Used when a doctor suspects both bacterial infection and significant inflammation are contributing to the eye problem.","evidence":"Limited"}]
Off-label uses: [{"condition":"Allergic conjunctivitis with secondary bacterial infection","description":"Occasionally used when allergic eye inflammation is complicated by a bacterial infection.","evidence":"Limited"},{"condition":"Chronic meibomian gland dysfunction with infection","description":"May be prescribed in some cases when infection and inflammation of the meibomian glands coexist.","evidence":"Limited"}]
Primary treatment for: Bacterial eye infections with inflammation
Also treats: Bacterial conjunctivitis, Bacterial blepharitis, Bacterial keratitis, Post-operative eye inflammation
📋 Drug Information
| Generic Name(s) | Chloramphenicol (10mg) + Dexamethasone (1mg) |
| Brand Name | dexa pc eye drop |
| Manufacturer | Calibre Pharmaceutical |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | |
| Route of Administration | Ophthalmic |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the tube tightly closed when not in use. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. The World Health Organization does not have a specific guideline for this combination product for ocular use. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research does not have a specific guideline for this combination product for ocular use. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Chloramphenicol is a broad-spectrum antibiotic that binds to the 50S ribosomal subunit of susceptible bacteria and blocks the peptidyl transferase reaction, preventing the formation of peptide bonds and thereby stopping bacterial protein synthesis. This action is usually bacteriostatic, meaning it stops bacteria from multiplying, and the body's immune system then clears the infection. Dexamethasone is a potent synthetic glucocorticoid that binds to glucocorticoid receptors in the cytoplasm, enters the nucleus, and modifies gene transcription. It increases the production of anti-inflammatory proteins such as lipocortin-1 and decreases the production of pro-inflammatory mediators like prostaglandins, leukotrienes, and cytokines. This reduces swelling, redness, and itching in the eye. The combination is designed to treat bacterial infection while simultaneously calming the inflammatory response.
Mechanism Steps
💡 How to Take dexa pc eye drop
Strength: Ophthalmic ointment containing chloramphenicol 10 mg and dexamethasone 1 mg per gram.
Dosage Information
| Adult Dosage | The usual adult dose is a small ribbon of ointment (about 1 cm) applied inside the lower eyelid of the affected eye one to three times daily, or as directed by your eye doctor. The frequency and duration depend on the type and severity of the infection. For some conditions, it may be applied every 3 to 4 hours initially, then less often. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for longer than prescribed without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician or eye specialist for appropriate use in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of corticosteroids, especially increased intraocular pressure and cataract formation. Use with caution and monitor eye pressure regularly. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for ocular use in patients with renal impairment. However, if systemic absorption is significant, chloramphenicol may accumulate. Use with caution in severe renal impairment and consult your doctor. |
| Hepatic Impairment | No specific dose adjustment is established for ocular use in patients with hepatic impairment. Since chloramphenicol and dexamethasone are metabolized in the liver, use with caution in severe liver disease and consult your doctor. |
| Maximum Daily Dose | The maximum daily dose for ocular use is not established from the available information. Follow your doctor's prescription exactly. Do not exceed the recommended frequency or duration. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dexa pc eye drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other corticosteroids | Major | |
| Live vaccines | Major | |
| CYP3A4 inhibitors | Moderate | |
| CYP3A4 inducers | Moderate | |
| Anticholinergic drugs | Moderate | |
| Other eye medications | Minor |
🚨 Major Interactions
- Other corticosteroids (oral, topical, inhaled)
- Live vaccines
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)
- CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
- Anticholinergic drugs
🍷 Alcohol Interaction
No specific interaction between alcohol and this eye ointment is established from the available information. However, alcohol may worsen certain eye conditions and can interact with other medicines you may be taking. It is best to avoid excessive alcohol while treating an eye infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chloramphenicol, dexamethasone, or any component of the ointment","Viral infections of the eye, including herpes simplex keratitis, vaccinia, and varicella","Fungal or parasitic eye infections","Untreated purulent ocular infections","History of herpes simplex keratitis","Glaucoma (unless specifically directed by an eye doctor)","Use in children under 2 years of age (unless directed by a doctor)"]
⚠️ Warnings & Precautions
["Prolonged use may increase the risk of increased intraocular pressure, glaucoma, and cataracts.","The steroid component can mask signs of infection and worsen existing infections.","Do not use this medicine for viral, fungal, or parasitic eye infections.","If symptoms do not improve within a few days, consult your eye doctor.","Do not touch the tip of the tube to any surface to avoid contamination.","Contact lenses should not be worn during treatment unless advised by your doctor.","Systemic absorption may occur, especially if the eye surface is damaged; use with caution in patients with liver or kidney disease.","Chloramphenicol can rarely cause aplastic anemia; report any signs of infection, bleeding, or fatigue.","Use with caution in patients with diabetes, as steroids can raise blood sugar.","Do not use this medicine after the expiry date."]
🤱 Lactation Safety
It is not known whether chloramphenicol or dexamethasone from this eye ointment passes into breast milk in significant amounts. Systemically absorbed chloramphenicol does pass into breast milk. Because of the potential for serious adverse reactions in a nursing infant, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose from ocular use is unlikely because the amount of medicine absorbed systemically is very small. If someone accidentally swallows the ointment, seek medical attention immediately. Symptoms of systemic chloramphenicol overdose may include nausea, vomiting, and diarrhea. Systemic dexamethasone overdose may cause increased blood sugar, high blood pressure, and fluid retention. Treatment is supportive and symptomatic. Contact a poison control center or emergency room if ingestion occurs.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Use this medicine only as prescribed by your eye doctor. Wash your hands thoroughly before and after applying the ointment. Do not touch the tip of the tube to your eye, eyelid, or any surface, because this can contaminate the ointment. Apply a thin ribbon of ointment inside the lower eyelid as directed. Close your eye gently and roll your eyeball to spread the medicine. Do not use this medicine for longer than your doctor recommends, because prolonged use can increase the risk of side effects. Do not share this medicine with anyone else. If you wear contact lenses, ask your doctor when you can wear them again. Do not drive or operate machinery until your vision is clear. Keep the tube tightly closed when not in use. Store it at room temperature and protect it from light and moisture. If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor before using this medicine. Do not use this medicine if the seal is broken or if the ointment looks discolored or has particles in it.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of corticosteroid-induced side effects, including increased intraocular pressure, glaucoma, and cataracts. They should be monitored closely by an eye doctor during treatment. The ointment may also cause more pronounced blurred vision in older adults, increasing the risk of falls. Use with caution and ensure proper application technique.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss the use of this medicine with your doctor. The safety of this combination during pregnancy is not well established. Systemic corticosteroids may be used in pregnancy when the benefit outweighs the risk, but ocular use should be evaluated by your doctor. Chloramphenicol should be used with caution, especially near term, due to potential risk to the newborn.
🏥 Post-Surgery Considerations
This medicine may be prescribed after eye surgery to prevent infection and reduce inflammation. Use it exactly as directed by your surgeon. Do not stop using it without consulting your surgeon. Follow all post-operative instructions, including avoiding rubbing your eyes and attending follow-up appointments.
🦷 Dental Procedures
There are no specific considerations for dental procedures while using this eye ointment. However, inform your dentist about all medicines you are taking, including eye medicines, as part of your medical history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There is no specific exercise restriction while using this medicine. However, if you have blurred vision after applying the ointment, avoid activities that require clear vision, such as swimming or contact sports, until your vision is clear. If you have an eye infection, avoid swimming pools and hot tubs to prevent spreading the infection.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause temporary blurred vision after application, which can affect driving, operating machinery, or performing tasks that require clear vision. It is best to apply the ointment when you do not need to drive or work for a few minutes. You can continue most daily activities, but avoid touching your eyes and maintain good hand hygiene to prevent spreading infection. If you work in a dusty environment, protect your eyes.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your symptoms do not improve within a few days, if they worsen, or if you experience any serious side effects such as eye pain, vision changes, or signs of allergic reaction. Do not stop using the medicine abruptly without consulting your doctor, especially if you have been using it for a long time, as the inflammation may return. Always complete the full course as prescribed.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of increased intraocular pressure, which may lead to glaucoma, and can cause cataracts. Prolonged use of the antibiotic component may lead to secondary infections with resistant bacteria or fungi. The steroid can also suppress the immune response in the eye, making it easier for infections to develop. Regular eye examinations, including measurement of intraocular pressure, are recommended if long-term use is necessary. Do not use this medicine for longer than prescribed without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Applying a warm, clean compress to the affected eye can help relieve discomfort and loosen crusts in blepharitis.
Evidence: Well-establishedGentle cleaning of the eyelids with a mild shampoo or commercial eyelid cleanser can help manage blepharitis.
Evidence: Well-establishedFor bacterial infections without significant inflammation, a doctor may prescribe antibiotic-only eye drops.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Corticosteroids can reduce the immune response to vaccines. If you are scheduled to receive a live vaccine, inform your doctor that you are using this medicine. Live vaccines should generally be avoided during treatment with corticosteroids, especially with prolonged use. Inactivated vaccines are generally safe but may be less effective.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep the cap tightly closed
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and heat. If you are crossing time zones, continue applying it at the same intervals as prescribed, but you may adjust the timing gradually. Check the customs regulations of your destination country regarding prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start noticing improvement in redness and irritation within 1 to 2 days. However, it is important to complete the full course as prescribed by your doctor.
A: No, you should not wear contact lenses while using this eye ointment unless your doctor specifically says it is okay. The ointment can cause blurred vision and may interact with the lenses.
A: If the tube tip touches your eye or any surface, it may become contaminated. Wipe the tip with a clean tissue and continue using it. If you are concerned, consult your pharmacist or doctor.
A: Pediatric dosing is not established from available information. Consult a pediatrician or eye specialist for appropriate use in children.
🤔 Common Patient Concerns
🔄 Substitutes for dexa pc eye drop
View AllAlternative brands with exact same active ingredient:
-
pychlor dexa eye ointmentMac Laboratories Ltd ₹10.62 52.8% CHEAPER
-
ocupol d eye ointmentCentaur Pharmaceuticals Pvt Ltd ₹11.13 50.5% CHEAPER
-
decol p eye ointmentIntas Pharmaceuticals Ltd ₹15.00 33.3% CHEAPER
-
eyclor-dexa eye dropUltramark Healthcare Pvt Ltd ₹23.44 4.2% COSTLIER
-
deximon p eye ointmentEntod Pharmaceuticals Ltd ₹24.26 7.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any red eye.
Fact: This medicine is only for bacterial eye infections with inflammation. It can worsen viral or fungal infections. - Myth: Steroid eye ointments are safe for long-term use.
Fact: Prolonged use can increase eye pressure, cause cataracts, and increase infection risk. Use only as prescribed. - Myth: You can stop using this medicine as soon as symptoms improve.
Fact: You should complete the full course as prescribed to prevent the infection from returning. - Myth: This medicine is safe to share with family members.
Fact: Never share eye medicines. This can spread infection and cause harm.
🔄 Alternative Options
Generic Alternatives
- Chloramphenicol and Dexamethasone Ophthalmic Ointment
Brand Alternatives
- Ocupol DX Eye Ointment