dersol 3% ointment - Salicylic Acid (3% w/w) medicine

dersol 3% ointment - Uses, Price, Side Effects & Substitutes

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๐Ÿญ East West Pharma ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is dersol 3% ointment used for?

Akralic 6% Ointment (Salicylic Acid) is used to treat DERMA. It contains Salicylic Acid (3% w/w), which Dissolves intercellular cement in stratum corneum, causing desquamation; also ha. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Salicylic Acid
  • Manufacturer: East West Pharma
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š dersol 3% ointment Uses & Benefits

Treatment of warts, calluses, corns, psoriasis, seborrheic dermatitis, acne, and other hyperkeratotic conditions.

Off-label uses: Treatment of ichthyosis, Dandruff, Fungal infections

๐Ÿ“‹ Drug Information

Generic Name(s)Salicylic Acid
Brand NameAkralic 6% Ointment
ManufacturerEast West Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassKeratoplastic and keratolytic agents
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC); keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed percutaneously; systemic absorption increases with larger surface area, higher concentration, and prolonged use.
DistributionDistributed widely; crosses placenta and enters breast milk.
Protein Binding50-80% bound to plasma proteins, primarily albumin.
MetabolismMetabolized in the liver via conjugation with glycine to form salicyluric acid and oxidation.
Half-Life2-3 hours at low doses; 15-30 hours at high doses.
ExcretionRenal excretion of salicylates and metabolites; excretion is pH-dependent.
BioavailabilitySystemic bioavailability is low with topical application but increases with damaged skin.
Onset of ActionWithin 1-2 hours for keratolytic effect.
Peak Plasma TimeNot well-defined for topical use; systemic peak may occur after several hours.
Duration of ActionUp to 6-8 hours depending on formulation and application.

How It Works

Dissolves intercellular cement in stratum corneum, causing desquamation; also has anti-inflammatory and antifungal properties.

Mechanism Steps

1Penetrates stratum corneum
2Dissolves intercellular cement (desmosomes) by breaking hydrogen bonds
3Causes shedding of corneocytes (desquamation)

๐Ÿ’ก How to Take dersol 3% ointment

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of dersol 3% ointment

โœ… Common Side Effects

  • Skin irritation
  • Redness
  • Peeling
  • Dryness
  • Stinging

๐Ÿšจ Serious Side Effects

  • Salicylism (tinnitus, hearing loss, dizziness, confusion)
  • Severe skin burns
  • Reye's syndrome in children

โš ๏ธ Rare Side Effects

  • Allergic contact dermatitis
  • Anaphylaxis
  • Metabolic acidosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Methotrexate Major Increased methotrexate toxicity due to reduced renal clearance
Warfarin Major Increased anticoagulant effect and bleeding risk
Probenecid Major Decreased uricosuric effect of probenecid
Sulfinpyrazone Major Decreased uricosuric effect of sulfinpyrazone
NSAIDs Moderate Increased risk of gastrointestinal ulceration
Corticosteroids Moderate Increased salicylate elimination
Antidiabetic agents Moderate Enhanced hypoglycemic effect
Uricosuric agents Moderate Decreased uricosuric effect
Acetazolamide Minor Increased salicylate toxicity due to acidosis
Antacids Minor Decreased salicylate absorption
Alcohol Minor Increased gastrointestinal irritation

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Probenecid
  • Sulfinpyrazone

โšก Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Antidiabetic agents
  • Uricosuric agents

โ„น๏ธ Minor Interactions

  • Acetazolamide
  • Antacids
  • Alcohol

๐Ÿฝ๏ธ Food Interactions

None known

๐Ÿท Alcohol Interaction

May increase risk of gastrointestinal irritation if ingested, but topical use minimal systemic effect.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to salicylates, children with viral infections (Reye's syndrome risk), severe renal impairment.

๐Ÿ“Š Monitoring Parameters

Monitor skin irritation, signs of salicylism (tinnitus, nausea, vomiting) with extensive use.

๐Ÿคฑ Lactation Safety

Caution; avoid application to breast area.

๐Ÿ’Š Overdose Management

Remove excess ointment; treat symptoms; for severe systemic toxicity, consider hemodialysis.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for dersol 3% ointment

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Alternative brands with exact same active ingredient (Salicylic Acid (3% w/w)):

Medical Note: Always consult your doctor before switching medications.

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