dersol 12% ointment - Salicylic Acid (12% w/w) medicine

Dersol 12% Ointment: A Complete Guide to Uses, Benefits, and Safety

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🏭 East West Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for keratolytic uses.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe burning, blistering, or swelling at the application site.
  • Signs of infection such as pus, increased pain, or fever.
  • Symptoms of salicylate toxicity: nausea, vomiting, dizziness, ringing in the ears, rapid breathing.
  • Allergic reaction: rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing.
  • No improvement after several weeks of treatment.
  • Skin becomes unusually dry, cracked, or bleeds.

If experiencing severe symptoms, call emergency services immediately.

What is dersol 12% ointment used for?

This medicine is a topical ointment containing 12% salicylic acid. It is used to treat skin conditions like psoriasis, seborrheic dermatitis, and warts by softening and removing thick, scaly skin. Apply a thin layer to the affected area as directed by your doctor, usually once or twice daily. Avoid contact with eyes and broken skin.

  • Generic Name: Salicylic Acid
  • Manufacturer: East West Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dersol 12% ointment के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से त्वचा की समस्याओं जैसे सोरायसिस, सेबोरहाइक डर्मेटाइटिस, और इक्थियोसिस के इलाज के लिए उपयोग की जाती है। यह त्वचा की मोटी और पपड़ीदार परत को नरम करके हटाने में मदद करती है। यह दवा मस्सों और कॉलस को हटाने में भी प्रभावी है। इसका उपयोग केवल त्वचा पर बाहरी रूप से किया जाता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में त्वचा पर हल्की जलन, खुजली, लालिमा और सूखापन शामिल हैं। कभी-कभी त्वचा का छिलना भी हो सकता है। यदि आपको गंभीर जलन, छाले, या सूजन हो, तो दवा का उपयोग बंद करें और तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर के निर्देशों का पालन करें। इसे केवल प्रभावित त्वचा पर पतली परत में लगाएं। आंखों, होंठों और म्यूकस मेम्ब्रेन के संपर्क से बचें। बच्चों की पहुंच से दूर रखें। गर्भावस्था या स्तनपान के दौरान उपयोग से पहले डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 dersol 12% ointment Uses & Benefits

[{"condition":"Psoriasis","description":"Helps to soften and remove thick scales on the skin, reducing roughness and improving the appearance of psoriatic plaques.","evidence":"Well-established"},{"condition":"Seborrheic dermatitis","description":"Used to treat scaling and flaking on the scalp and other oily areas of the skin.","evidence":"Well-established"},{"condition":"Ichthyosis","description":"Provides symptomatic relief by hydrating and exfoliating dry, scaly skin associated with ichthyosis.","evidence":"Well-established"},{"condition":"Calluses and corns","description":"Softens thickened skin on the feet and hands, making it easier to remove.","evidence":"Well-established"},{"condition":"Warts","description":"Can be used as part of wart treatment to peel away infected skin layers.","evidence":"Well-established"},{"condition":"Keratosis pilaris","description":"Helps to smooth rough bumps on the arms, thighs, and other areas by exfoliating the skin.","evidence":"Limited"}]

Off-label uses: [{"condition":"Acne vulgaris","description":"Sometimes used off-label to help unclog pores and reduce mild acne, though other treatments are more commonly prescribed.","evidence":"Limited"},{"condition":"Hyperkeratosis of the feet","description":"May be used to reduce thick, hardened skin on the soles of the feet not caused by calluses or corns.","evidence":"Limited"}]

Primary treatment for: Psoriasis

Also treats: Seborrheic dermatitis, Ichthyosis, Calluses and corns, Warts, Keratosis pilaris

📋 Drug Information

Generic Name(s)Salicylic Acid
Brand NameAkralic 6% Ointment
ManufacturerEast West Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassKeratoplastic and keratolytic agents
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Keep away from direct sunlight and moisture. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine only to the affected area and avoid surrounding healthy skin.
2
Wash your hands thoroughly after applying the ointment to prevent spreading it to other areas.
3
Do not use airtight dressings over the treated area unless your doctor specifically instructs you to.
4
If you are using other topical medicines, apply them at different times to avoid interactions.
5
Stop using this medicine and consult your doctor if you develop severe irritation or signs of infection.
6
Keep a record of your application schedule to ensure you do not miss doses.
7
Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before using this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Thick, scaly patches on skin
This medicine is commonly prescribed for psoriasis and other scaling conditions.
Likely Use
✅
Warts on hands or feet
This medicine can help soften and remove warts.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Acne
This medicine is not a primary acne treatment, though it may be used off-label.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSalicylic acid is absorbed through the skin. The extent of absorption depends on the concentration, the area of application, the duration of contact, and the condition of the skin. Damaged or inflamed skin absorbs more than intact skin. Systemic absorption can occur, especially when applied to large areas or under occlusion.
DistributionOnce absorbed, salicylic acid is distributed throughout the body. It is known to cross the placenta and is excreted in breast milk. It may also accumulate in tissues with high metabolic activity.
Protein BindingSalicylic acid is approximately 80-90% bound to plasma proteins, primarily albumin.
MetabolismSalicylic acid is metabolized in the liver by conjugation with glycine to form salicyluric acid, and by glucuronidation and oxidation. The metabolites are inactive.
Half-LifeThe elimination half-life of salicylic acid is dose-dependent. At low doses, it is about 2-3 hours, but at higher doses, it can increase to 15-30 hours due to saturation of metabolic pathways.
ExcretionSalicylic acid and its metabolites are excreted primarily in the urine. The rate of excretion is influenced by urine pH; alkaline urine increases excretion.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of action for this medicine is not immediate. It may take several days to weeks of regular use to see noticeable improvement in skin scaling and thickening.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effects of this medicine last as long as it is used regularly. Once stopped, the skin may gradually return to its previous state.

How It Works

This medicine works by softening and breaking down the keratin in the outer layer of the skin. Salicylic acid is a beta-hydroxy acid that penetrates the skin and disrupts the bonds between dead skin cells, causing them to shed more easily. This process is known as keratolysis. By reducing the thickness of the stratum corneum, this medicine helps to relieve scaling, roughness, and thickening. It also has mild antimicrobial properties that can help prevent secondary infections in damaged skin.

Mechanism Steps

1
Penetration into the skin: Salicylic acid penetrates the outer layer of the skin, especially when the skin is hydrated.
2
Disruption of keratin bonds: It breaks the bonds between dead skin cells by dissolving the intercellular cement that holds them together.
3
Exfoliation: The loosened dead skin cells are shed, reducing scaling and thickening.
4
Improved skin texture: As the outer layer is removed, the skin becomes smoother and softer.

💡 How to Take dersol 12% ointment

Strength: Ointment containing Salicylic Acid 12% w/w.

1Wash your hands thoroughly before and after applying the medicine.
2Clean and dry the affected area gently.
3Apply a thin layer of the ointment to the affected skin.
4Rub it in gently until it is absorbed.
5Do not cover the area with a bandage unless your doctor tells you to.
6Wash your hands immediately after use, unless your hands are the treated area.
7Avoid getting the medicine in your eyes, nose, or mouth.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area once or twice daily, or as directed by your doctor. The frequency and duration of treatment depend on the condition being treated and your response to therapy. For psoriasis, it may be used once daily. For warts, it may be applied once or twice daily for several weeks. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use more than the prescribed amount or for longer than recommended without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to the effects of salicylic acid, especially if they have kidney or liver problems. Use with caution and under medical supervision. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is provided for topical use. However, use with caution in patients with renal impairment due to the potential for systemic absorption and reduced clearance of salicylates. Consult your doctor.
Hepatic ImpairmentNo specific dose adjustment is provided for topical use. However, use with caution in patients with hepatic impairment due to the potential for systemic absorption and altered metabolism of salicylates. Consult your doctor.
Maximum Daily DoseNot established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of dersol 12% ointment

✅ Common Side Effects

Mild burning or stinging (Common (5-10%))
This usually goes away with continued use. If it persists, consult your doctor.
Redness (Common (5-10%))
Apply less frequently or use a lower strength if advised by your doctor.
Peeling or flaking (Common (5-10%))
This is often a sign that the medicine is working. Moisturize the area if needed.
Itching (Common (5-10%))
Avoid scratching. If itching is severe, stop use and consult your doctor.
Dryness (Common (5-10%))
Use a gentle moisturizer after the medicine has dried.

🚨 Serious Side Effects

Severe skin irritation or blistering (Rare (<0.1%))
Stop using the medicine and seek medical attention if you develop blisters or severe redness.
Salicylate toxicity (Rare (<0.1%))
Seek immediate medical help if you experience nausea, vomiting, dizziness, ringing in the ears, or rapid breathing.
Allergic reaction (Rare (<0.1%))
Seek emergency care if you notice swelling of the face, lips, tongue, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Systemic salicylism
Requires immediate medical attention. Symptoms include confusion, headache, and rapid breathing.
Contact dermatitis
Discontinue use and consult a dermatologist.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Topical retinoids Moderate
Topical corticosteroids Moderate
Other topical salicylates Major

🚨 Major Interactions

  • Other topical salicylates
  • Oral anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Topical retinoids
  • Topical corticosteroids

🍷 Alcohol Interaction

No known interaction between this medicine and alcohol when used topically. However, if you consume alcohol excessively, it may increase the risk of stomach irritation if the medicine is absorbed systemically. It is always best to consult your doctor about alcohol use while on any medication.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Allergy to salicylic acid or any other ingredient in the ointment.","Application to broken, inflamed, or infected skin.","Use on large areas of the body without medical supervision.","Use in children under 2 years of age unless prescribed by a doctor.","Use on the face, genitals, or mucous membranes unless directed by a doctor."]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on moles, birthmarks, warts with hair, or genital warts without medical advice.","Do not use on irritated or broken skin.","Do not cover the treated area with airtight dressings unless instructed.","Consult a doctor before use if you are pregnant, breastfeeding, or have diabetes, poor circulation, or kidney or liver disease.","Keep out of reach of children.","If symptoms persist or worsen, discontinue use and consult a doctor."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk in significant amounts when used topically. However, salicylic acid is excreted in breast milk when taken orally. To be safe, avoid applying this medicine to the breast area, and consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose from topical use is unlikely unless large amounts are applied over a long period or the medicine is ingested. If you accidentally swallow this medicine, seek emergency medical attention immediately. Symptoms of salicylate toxicity include nausea, vomiting, dizziness, ringing in the ears, rapid breathing, and confusion. Treatment is supportive and may include activated charcoal, intravenous fluids, and correction of electrolyte imbalances.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before using this medicine, read the label carefully and follow your doctor's instructions exactly. Apply a thin layer only to the affected area and avoid contact with the eyes, lips, inside the nose, and other mucous membranes. Wash your hands thoroughly before and after applying the ointment, unless your hands are the treated area. Do not cover the treated area with airtight dressings unless your doctor tells you to, as this can increase absorption and the risk of side effects. Avoid using this medicine on large areas of the body, on broken skin, or for prolonged periods without medical supervision. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine on children unless a doctor has specifically prescribed it. Keep this medicine out of the reach of children. If you accidentally swallow this medicine, seek emergency medical help immediately. Do not use this medicine after the expiry date, and store it as directed on the packaging. If your condition does not improve or gets worse after a few weeks of treatment, stop using the medicine and consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of salicylic acid and may be at higher risk of systemic absorption. Use with caution and under medical supervision. Monitor for signs of irritation or toxicity.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

🏥 Post-Surgery Considerations

Avoid applying this medicine to surgical wounds or areas of broken skin unless specifically instructed by your surgeon. Consult your doctor before using it after surgery.

🦷 Dental Procedures

No specific precautions are required for dental procedures. However, inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep your skin well moisturized to prevent excessive dryness.
🥗
Avoid scratching or picking at treated areas.
😴
Wear loose-fitting clothing to reduce friction on treated skin.
💧
Use gentle, fragrance-free cleansers and moisturizers.
🧘
Protect treated skin from sun exposure by wearing protective clothing.
🌞
Maintain a healthy diet and stay hydrated to support skin health.

🏋️ Exercise Considerations

No specific exercise restrictions are required while using this medicine. However, if you have skin irritation or open sores, avoid activities that may cause friction or sweating on the affected area. Consult your doctor if you experience discomfort during exercise.

🥗 Diet Recommendations

Include foods rich in omega-3 fatty acids, such as fish and flaxseeds, to support skin health.
Eat plenty of fruits and vegetables rich in antioxidants.
Stay well hydrated by drinking adequate water.
Limit intake of processed foods and added sugars.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience skin irritation or discomfort, you may want to avoid activities that require concentration until you know how it affects you.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your condition does not improve after several weeks, if it worsens, or if you experience severe side effects. Do not stop suddenly if you are using it for a chronic condition without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to skin irritation, dryness, and increased sensitivity. Prolonged use over large areas may increase the risk of systemic absorption and salicylate toxicity. It is important to use it only as directed and to have regular follow-ups with your doctor to monitor for any adverse effects. Do not use continuously for more than 6 weeks without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Moisturizers

Can help soothe dry, scaly skin and complement the effects of this medicine.

Evidence: Well-established
Phototherapy

For psoriasis, light therapy may be used in addition to topical treatments.

Evidence: Well-established
Oral medications

For severe cases, systemic treatments may be prescribed by a specialist.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue applying it according to your usual schedule. Keep it in your carry-on luggage to avoid loss or temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with chronic plaque psoriasis on his elbows and knees.
He was prescribed this medicine to apply twice daily. After two weeks, he noticed significant reduction in scaling and itching. He also used a moisturizer to combat dryness. He was advised to avoid using it on his face.
💡 Lesson: Consistent application and moisturizing can improve outcomes and reduce side effects.
👤 A 35-year-old woman with a painful corn on her foot.
She applied this medicine once daily after soaking her foot in warm water. After 10 days, the corn softened and could be gently removed. She was careful not to apply it to the surrounding healthy skin.
💡 Lesson: Soaking the area before application can enhance the keratolytic effect.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: It may take several days to weeks of regular use to see noticeable improvement. For warts, it may take several weeks.

Q: Can I use this medicine on my face?

A: Only if your doctor has specifically instructed you to. It can cause irritation on sensitive skin.

Q: What if I miss a dose?

A: Apply it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Q: Is it safe during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long can I use this medicine continuously?
  • Will this medicine stain my clothes?
  • Can I use this medicine with other skin products?
  • Is this medicine safe for children?
  • What should I do if I get this medicine in my eyes?

🔄 Substitutes for dersol 12% ointment

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Dersol 12% ointment can cure skin conditions permanently.
    Fact: This medicine helps manage symptoms but does not cure chronic skin conditions. It should be used as part of a comprehensive treatment plan.
  • Myth: More ointment means faster results.
    Fact: Applying more than the recommended amount can increase the risk of side effects and does not speed up healing.
  • Myth: It is safe to use on any skin problem.
    Fact: This medicine should only be used for conditions it is prescribed for. Using it on other skin problems can cause irritation or harm.

🔄 Alternative Options

Generic Alternatives

  • Salicylic acid 12% ointment

Brand Alternatives

  • Dersol 12% Ointment

📊 Comparison with Similar Medicines

[{"medicine":"Salicylic acid 12% ointment","strength":"12% w/w","form":"Ointment","primary_use":"Psoriasis, seborrheic dermatitis, warts"},{"medicine":"Salicylic acid 6% ointment","strength":"6% w/w","form":"Ointment","primary_use":"Mild scaling, acne"},{"medicine":"Urea 10% cream","strength":"10% w/w","form":"Cream","primary_use":"Dry, rough skin, keratosis"}]

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